KR20170117841A - Improvement or treatment of atopic dermatitis using a purified composition obtained from raw ore powder and charcoal powder - Google Patents

Abstract

The present invention relates to a composition for improving or treating atopic dermatitis, and more particularly, it relates to a composition for improving or treating atopic dermatitis, and more particularly, to a composition for preventing or treating atopic dermatitis by suppressing an hypersensitivity reaction using minerals and plant extracts, And to a composition for improving or treating atopic dermatitis using purified water obtained from an increased raw ore powder and charcoal powder.

Description

TECHNICAL FIELD The present invention relates to a composition for improving or treating atopic dermatitis using purified water obtained from raw ore powder and charcoal powder,

The present invention relates to a composition for improving or treating atopic dermatitis, and more particularly, it relates to a composition for improving or treating atopic dermatitis, and more particularly, to a composition for preventing or treating atopic dermatitis by suppressing an hypersensitivity reaction using minerals and plant extracts, And to a composition for improving or treating atopic dermatitis using purified water obtained from an increased raw ore powder and charcoal powder.

As is well known, atopic dermatitis is a chronic inflammatory skin disease that occurs most often during infancy and childhood, which is repeated with aggravation and aggravation, accompanied by rash and severe itching by external stimulants.

Accelerated urbanization and industrialization, along with the development of industry, have caused environmental pollution, and this environmental pollution has rapidly spread to the occurrence of atopic dermatitis and has become a serious social problem.

The pathogenesis of atopic dermatitis has not yet been elucidated. However, the pathogenesis of atopic dermatitis has not yet been elucidated. However, pathological factors such as a hypersensitivity reaction due to an increase in IgE antibody or a functional deficiency due to a cracking differentiation of T lymphocytes, It is now thought to be a disease in which immunological abnormalities are involved.

In addition, it is reported that extrinsic atopic dermatitis, which accounts for most of atopic dermatitis, is caused by IgE-related immune mechanism, and delayed immune response due to T-cell abnormality is involved rather than immediate type immune response to specific allergens.

Recently, Th2-related cytokines such as IL-4, which induce IgE production from B cells, have been reported to be the cause of atopy (JS Kang et al., Inhibition of atopic dermatitis by topical application of silymarin in NC / Nga mice. Intl Immunopharm (2008) 8 1475-1480).

Meanwhile, in order to improve, treat and manage atopic dermatitis, it is common to prescribe a moisturizing agent that maintains moisture on the surface of the skin and a steroid hormone, that is, a topical corticosteroid preparation, to improve the inflammatory reaction.

However, local adrenocortical hormone is troublesome for long-term use because it causes various skin side effects such as skin atrophy, vasodilatation, pigment desalination, and swelling ancestry.

Therefore, the development of atopic treatments or adjuvants using natural candidate substances with anti-atopic efficacy and very low side effects is proceeding in the fields of pharmaceuticals and cosmetics, but various clinical experiments and development periods are long, .

Accordingly, compositions using natural materials capable of improving or alleviating atopic dermatitis having various therapeutic-auxiliary functions as described below, and further obtaining therapeutic effects, have been disclosed.

Korean Patent Registration No. 10-0682048 (2007.02.06), 'Herbal composition for treating atopy' Korean Patent Registration No. 10-1122163 (Feb. 23, 2012), " Hyaluronic acid derivatives effective for atopic dermatitis and methods for producing the same, Korean Patent Registration No. 10-1257435 (Apr. 17, 2013), 'Cosmetic composition for alleviating atopic skin and skin irritation containing sage extract, lemon balm extract, mugwort extract and onion extract as active ingredients' Korean Patent Registration No. 10-1382115 (Apr. 04, 2014), "Food Composition for Atopic Dermatitis Containing Ginseng Fruit Extract" Korean Patent Registration No. 10-1412500 (Apr. 20, 2014), "Cosmetic Composition for Improving Atopic Skin Containing Bamboo Fermented Herbal Extracts as Active Ingredients and Method for Producing the Same" Korean Patent Laid-Open No. 10-2015-0088154 (Jul. 31, 2015), 'Compositions for alleviating or improving atopic dermatitis including gossam, licorice and white tiger blood extract, Korean Patent Publication No. 10-2015-0092910 (Aug. 17, 2015), "composition for preventing or treating atopy which has antioxidant and anti-inflammatory effect" Korean Patent Laid-Open No. 10-2015-0120741 (Oct. 27, 2015), a composition for prevention or improvement of atopic dermatitis comprising as an active ingredient a mixture of persimmon peel, persimmon leaf, persimmon leaf, Korean Patent Publication No. 10-2015-0129135 (Nov. 19, 2015), "Pharmaceutical composition for prevention or treatment of atopy"

DISCLOSURE OF THE INVENTION The present invention has been made in view of the above-described problems in the prior art, and it is an object of the present invention to provide a cosmetic composition which suppresses the hypersensitivity reaction by using minerals and plant extracts which are natural materials, And a composition for improving or treating atopic dermatitis using purified water obtained from a raw ore powder and a charcoal powder that have improved dermatitis improving effect.

As a means for achieving the above-mentioned object, the present invention provides a method for separating a raw ore powder obtained by grinding a raw ore powder having a particle size of 0.1-0.3 mm and water at a weight ratio of 7: 3 in a mixed state to obtain distilled water, Purified water obtained by filtration through a charcoal powder having a particle size of 0.2 cm; 5-8 parts by weight of calendula extract, 4-6 parts by weight of white mushroom extract, 3-5 parts by weight of elm extract, 5-8 parts by weight of green tea extract, 3-5 parts by weight of an acidic sea extract, 6 to 10 parts by weight of an amodimethicone, 3-6 parts by weight of a mulberry extract, 6 to 10 parts by weight of sodium pcine, 3-6 parts by weight of hyaluronic acid and 4-8 parts by weight of an extract of snowballs The present invention also provides a composition for improving or treating atopic dermatitis using purified water obtained from raw ore powder and charcoal powder.

At this time, 5-10 parts by weight of allantoin is added to 100 parts by weight of the purified water.

Further, the present invention is also characterized in that 4-8 parts by weight of flower extract is added to 100 parts by weight of the purified water.

According to the present invention, by providing a functional composition effective for improvement of atopic treatment by using natural materials which are harmless to the human body rather than being harmless to the human body, there is no skin allergy reaction, have.

Hereinafter, preferred embodiments according to the present invention will be described in detail.

Before describing the present invention, the following specific structural or functional descriptions are merely illustrative for the purpose of describing an embodiment according to the concept of the present invention, and embodiments according to the concept of the present invention may be embodied in various forms, And should not be construed as limited to the embodiments described herein.

In addition, it should be understood that the embodiments according to the concept of the present invention include various modifications, equivalents, and alternatives included in the spirit and technical scope of the present invention, .

The composition for improving or treating atopic dermatitis using purified water obtained from raw ore powder and charcoal powder according to the present invention is one of very important constituents because it is made into a liquid form and can be sprayed directly onto the skin, It is necessary to be able to maintain the fixed state of the skin stably while being able to obtain the soothing effect of the purified water itself, while manifesting the unique characteristics of each material by well mixing the ingredients.

To this end, in the present invention, purified water serving as a basic base is used as raw ore powder and water obtained from charcoal powder.

Here, the raw ore powder can be obtained by pulverizing raw ore with a particle size of 0.1-0.3 mm, and the raw ore is an ore collected from Youngwol in Gangwon-do.

This stone is a mineral that emits far infrared rays in the wavelength range of 8 ~ 12 ㎛ which is beneficial for life. In particular, the stone taken from Yeongwol, Gangwon province is determined as the only stone in the world as a result of the molecular structure analysis by the resource research institute. .

This kind of biotite is a special structure which is completely different from other ore, and it emits bio-cell activation energy without pore inside the rock, so that the water in the air is monomolecularly ionized by the bio-cell activation energy to generate hydroxy anion It is known to provide anion effect semi-permanently by applying anion to oxygen.

In addition, by directly reacting with human living cells, resonance phenomenon of water molecule of living body and vibration phenomenon of cell molecules elevate body temperature to give a sweating effect (sweat effect), thereby giving a very beneficial effect to the living body .

In particular, the Applicant has discovered that the activated ores are more activated and emit a large amount of far-infrared rays. To further facilitate this, the raw ore is pulverized, and then water is added thereto at a temperature of about 800-900 ° C to form 4- After boiling for about 8 hours, steam was collected and cooled to make distilled water.

At this time, the ratio of the water to the raw ore powder was maintained at a weight ratio of 3: 7. When the water was evaporated and collected, the same amount of water was supplemented while heating the water. Respectively.

The distilled water thus obtained was filtered through a barrel containing charcoal powder having a grain size of 0.1-0.2 cm, which is half the size of rice grain, to obtain purified water used in the present invention.

By obtaining purified water in this manner, the purified water itself is configured to have not only the self-purification ability but also the function as the activated water having the cell sedative effect.

The composition according to the present invention comprises purified water obtained by the above-mentioned method and 5-8 parts by weight of calendula extract, 4-6 parts by weight of white mushroom extract, 3-5 parts by weight of elm extract, 5-8 parts by weight of an acidic sea bream extract, 3-5 parts by weight of an acidic sea bream extract, 6-10 parts by weight of amodimethicone, 3-6 parts by weight of a mackerel extract, 6-10 parts by weight of sodium PCAE, 3-6 parts by weight of hyaluronic acid 3-6 And 4 to 8 parts by weight of an eyeball collagen extract.

At this time, the above-mentioned Calendula extract is added in the present invention in order to obtain an effect of soothing the skin, by using an extract obtained by putting calendula leaf which has been mainly used as a medicine for digestive and respiratory diseases in a hot water tank together with ionized water. -8 parts by weight.

In addition, the white mushroom extract is effective for enhancing the immunity, and the dry and atopic skin has a large polysaccharide content, thereby regenerating and repairing damaged cells, thereby exhibiting anti-aging and moisturizing effects.

Moreover, because vitamin D is 20 times more abundant than shiitake mushrooms, it provides nutritional benefits to the skin.

When the amount of the mushroom extract is less than 4 parts by weight, the effect of enhancing the immunity and the effect of regenerating the skin are deteriorated. Therefore, the amount of the mushroom extract should be limited to the above range .

In addition, the elm extract may be used in an extract obtained by fermenting rhizome, but it is effective in releasing heat and toxins inside the skin because it contains tannin, and it may cause acidification of skin when used excessively.

In addition, the green tea extract uses a liquid extracted from green tea leaf. When tea is taken as a tea, it gives mental vitality to refresh the mood, suppresses the growth of various bacteria, prevents poisoning and cold, In the present invention, by spraying in the form of an extract, the effect of decomposing and extinguishing toxic substances is obtained.

It is known to be due to the abundance of polyphenols contained in green tea. Catechin in green tea is combined with heavy metals and nicotine in the body to excrete to the outside of the body. It over-consumes food and digests glycogen to accelerate metabolism. It has also been reported to reduce weight and prevent obesity.

Particularly, in the present invention, it is added in order to prevent skin troubles due to the release of toxic substances, and if it is added in an amount of less than 5 parts by weight, it is difficult to prevent trouble and skin irritation, It should be limited.

In addition, the above-mentioned Cynanchum paniculatum extract is added together with green tea extract to enhance sedation.

This mountain is known as Sejanggyeong, and it grows in the sunny grasses of the mountains. The stems are straight and thin and long between the nodes. The flowering period is around August to September, light yellowish brown, (Xu Xianglong) is used as a medicinal product, is known to have analgesic, sedative, antibacterial effect.

In the present invention, it is added in order to implement an analgesic function, and therefore it is not necessary to add an excessive amount, and it should be added within the above range.

In addition, the above-mentioned amodimicecone is a kind of silicone oil, and purified water according to the present invention is added in order to attract the pharmaceutical ingredient and penetrate into the skin, so as to deposit on the skin surface, Is added in a range of 6 to 10 parts by weight for a function of increasing the dispersibility of the components.

It is known that the mackerel extract is a natural extract extracted from the mackerel leaves. The mackerel leaves have been known to have excellent effects on skin diseases, skin regeneration and hemostasis, and have been used for treating skin diseases. It has been reported that it contains 20 kinds of ingredients such as casinol, glycosides, phenols, organic acids, tannins, and flavonoids and is effective for treating atopy.

In the present invention, when extracting the extract from a mulberry leaf, the mulberry leaves and roots are put into a pot at a weight ratio of 80:20, and the resultant is filtered and added within a range of 3-6 parts by weight.

In addition, the sodium pcine is added to moisturize the skin. It keeps moisturizing properly, suppresses itching, and calms the rash caused by atopy.

In addition, the hyaluronic acid is added in a range of 3-6 parts by weight to protect the skin. The hyaluronic acid enhances skin immunity and detoxifies to minimize skin troubles, And has the property of inhibiting activation.

Particularly, the above-mentioned hyaluronic acid is an acidic polysaccharide in which N-acetylglucosamic acid is bonded to each other in a straight-chain manner, and is responsible for maintaining the moisture metabolism and structure of the tissue in addition to mucous lubrication It is a substance that defends against the invasion of bacteria and is degraded by hyaluronidase.

In addition, the above-mentioned snowball pocket extract can be added in the range of 4-8 parts by weight. The snowball pocket is one year or two year old and grows as a seed. When it is toxic, it causes dyspnea and heart attack When it is applied to the skin, it performs pain relief, detoxification, and bruising relief.

In addition, since the composition according to the present invention has a soothing and alleviating action of the skin, allantoin may be added in an amount of 5 to 10 parts by weight based on 100 parts by weight of the purified water, in order to further enhance the effect of preventing skin troubles.

At this time, the allantoin is a natural substance extracted from places such as oat flour, beetroot, wheat germ, and the like.

In addition, 4-8 parts by weight of flower extract may be added to 100 parts by weight of the purified water in order to nourish the skin to suppress skin swelling and pain, and to alleviate pain.

At this time, the flower bud is a biennial plant belonging to the cruciferous family. It has been used as a juice from a whale, and has been used as a medicine to remove cough, sputum and swelling of the body.

In particular, since the flower bud contains vitamins, minerals, calcium, potassium, saponins, flavonoids and polyphenols, it provides nutrition to the skin as well as antioxidant prevention and is excellent in suppressing pain and swelling of the skin. The extracted extract is used.

The composition according to the present invention composed of this composition is prepared by pouring the additives into a stirrer, pouring the purified water, heating the mixture to 40-50 DEG C in a lukewarm state, stirring the mixture for 20-30 minutes at 100-150 DEG C, So that the liquid phase can be maintained.

Hereinafter, examples will be described.

[Example 1]

To confirm whether the composition according to the present invention is effective in improving atopic treatment, 6 parts by weight of calendula extract, 5 parts by weight of white mushroom extract, 4 parts by weight of elm extract, 4 parts by weight of green tea 6 parts by weight of the extract, 4 parts by weight of the acidic sea bream extract, 7 parts by weight of amodimethicone, 5 parts by weight of the extract of mulberry tree, 8 parts by weight of sodium PCA, 4 parts by weight of hyaluronic acid, The mixture was heated to 42 ° C and heated to 120 ° C for 25 minutes to be completely dispersed.

[Example 2]

8 parts by weight of allantoin was added to 100 parts by weight of purified water in the same manner as in Example 1, except that 100 parts by weight of purified water was added.

[Example 3]

In the same manner as in Example 1, 6 parts by weight of flower extract was added to 100 parts by weight of the purified water.

Analysis of the atypical-associated allergic antigens (35 species) by the GC / SIM analysis of the solutions of Examples 1, 2, and 3 was conducted and all 35 species were not detected.

In addition, 10 children with atopic inflammation rubbed the inflammation site and sprayed the solutions of Examples 1, 2, and 3, and after 1, 2, 3, 4, and 5 hours elapsed, Erythema, and itching were observed.

As a result of evaluation, in Example 1, the time required for inflammation to sink was 4 hours, no itching occurred, and after 5 hours, erythema disappeared and a little bit of stinging was answered.

In the case of Example 2, inflammation, swelling and pain disappeared in 1 hour and 30 minutes, no itching occurred, erythema disappeared in 2 hours, and there was no stinging, indicating that the skin soothing effect was great.

In Example 3, inflammation, swelling and pain disappeared at 3 hours, no itching occurred, and erythema disappeared after 4 hours, and there was no stinging.

From the results of the evaluation, it was confirmed that the composition according to the present invention can not fundamentally effect atopic dermatitis, but is effective for alleviating atopic dermatitis by alleviating inflammation.

Claims (3)

The raw ore powder obtained by pulverization with a particle size of 0.1-0.3 mm and water were mixed at a weight ratio of 7: 3 and evaporated to obtain distilled water. The distilled water was filtered through a charcoal powder having a particle size of 0.1-0.2 cm, Wow;
With respect to 100 parts by weight of the purified water,
5-8 parts by weight of calendula extract, 4-6 parts by weight of white mushroom extract, 3-5 parts by weight of elm extract, 5-8 parts by weight of green tea extract, 3-5 parts by weight of acidic sea bream extract, 3 to 6 parts by weight of hyaluronic acid, and 4-8 parts by weight of an extract of snowballs are contained. A composition for improving or treating atopic dermatitis using purified water obtained from powder and charcoal powder.
The method according to claim 1,
Wherein allantoin is added in an amount of 5-10 parts by weight with respect to 100 parts by weight of the purified water, and purified water obtained from the powder of charcoal and charcoal powder is used for improving or treating atopic dermatitis.
The method according to claim 1,
The composition for improving or treating atopic dermatitis according to claim 1, wherein 4-8 parts by weight of a flower extract is added to 100 parts by weight of the purified water.