KR20120120965A - 자작나무 알레르기에 대한 펩티드백신 - Google Patents

자작나무 알레르기에 대한 펩티드백신 Download PDF

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Publication number
KR20120120965A
KR20120120965A KR1020127024247A KR20127024247A KR20120120965A KR 20120120965 A KR20120120965 A KR 20120120965A KR 1020127024247 A KR1020127024247 A KR 1020127024247A KR 20127024247 A KR20127024247 A KR 20127024247A KR 20120120965 A KR20120120965 A KR 20120120965A
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KR
South Korea
Prior art keywords
polypeptide
gly
variant
ser
peptide
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Ceased
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KR1020127024247A
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English (en)
Korean (ko)
Inventor
마크 라쉬
로드릭 피터 헤프너
폴 레이들러
가이 레이튼
Original Assignee
서카시아 리미티드
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Application filed by 서카시아 리미티드 filed Critical 서카시아 리미티드
Publication of KR20120120965A publication Critical patent/KR20120120965A/ko
Ceased legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/35Allergens
    • A61K39/36Allergens from pollen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/35Allergens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/14Decongestants or antiallergics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5023Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on expression patterns
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047Cells of the immune system
    • G01N33/505Cells of the immune system involving T-cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/577Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 tolerising response
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/04Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Botany (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pulmonology (AREA)
KR1020127024247A 2010-02-15 2011-02-15 자작나무 알레르기에 대한 펩티드백신 Ceased KR20120120965A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1002559.1A GB201002559D0 (en) 2010-02-15 2010-02-15 Birch peptides for vaccine
GB1002559.1 2010-02-15
PCT/GB2011/000206 WO2011098778A2 (en) 2010-02-15 2011-02-15 Peptides for vaccines against birch allergy

Publications (1)

Publication Number Publication Date
KR20120120965A true KR20120120965A (ko) 2012-11-02

Family

ID=42110757

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020127024247A Ceased KR20120120965A (ko) 2010-02-15 2011-02-15 자작나무 알레르기에 대한 펩티드백신

Country Status (20)

Country Link
US (2) US9017689B2 (enExample)
EP (2) EP3056213A1 (enExample)
JP (2) JP5926198B2 (enExample)
KR (1) KR20120120965A (enExample)
CN (1) CN102762225B (enExample)
AU (1) AU2011214104B2 (enExample)
CA (2) CA3139588A1 (enExample)
DK (1) DK2536429T3 (enExample)
EA (1) EA201290792A1 (enExample)
ES (1) ES2573651T3 (enExample)
GB (2) GB201002559D0 (enExample)
HR (1) HRP20160481T1 (enExample)
HU (1) HUE029138T2 (enExample)
IL (1) IL221196A0 (enExample)
MX (1) MX2012009431A (enExample)
NZ (1) NZ602380A (enExample)
PL (1) PL2536429T3 (enExample)
SG (1) SG183198A1 (enExample)
SI (1) SI2536429T1 (enExample)
WO (1) WO2011098778A2 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201002559D0 (en) * 2010-02-15 2010-03-31 Circassia Ltd Birch peptides for vaccine
JP2015509487A (ja) * 2012-02-07 2015-03-30 ラ ホーヤ インスティテュート フォー アレルギー アンド イムノロジーLa Jolla Institute For Allergy And Immunology アレルゲンタンパク質由来のエピトープ並びに免疫応答モジュレーションのための方法及び使用
GB201209862D0 (en) 2012-06-01 2012-07-18 Circassia Ltd Cladosporium peptides
GB201211586D0 (en) * 2012-06-29 2012-08-15 Circassia Ltd Japanese cedar peptides for preventing or treating allergy
US20150088644A1 (en) 2013-09-23 2015-03-26 Facebook, Inc., a Delaware corporation Predicting User Interactions With Objects Associated With Advertisements On An Online System
CN106699584B (zh) * 2016-12-30 2018-06-26 南京农业大学 一种利用花粉作为天然催化剂制备的γ-氨基丁酸及其制备方法和应用
NZ759513A (en) 2017-06-01 2022-01-28 Regeneron Pharma Human antibodies to bet v 1 and methods of use thereof
CN110175468B (zh) * 2019-05-05 2020-12-01 浙江工业大学 一种保留分布特征的姓名脱敏方法
CN115633666B (zh) * 2021-07-19 2025-11-18 四川大学华西医院 人源化双致敏动物模型和系统性过敏动物模型的构建方法及其应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
US5399346A (en) 1989-06-14 1995-03-21 The United States Of America As Represented By The Department Of Health And Human Services Gene therapy
WO1994001560A1 (en) 1991-07-12 1994-01-20 Immulogic Pharmaceutical Corporation Allergenic proteins and peptides from japanese cedar pollen
US5968526A (en) 1994-04-14 1999-10-19 Immulogic Pharamaceutical Corporation T cell epitopes of the major allergens from Dermatophagoides (house dust mite)
WO1999034826A1 (en) 1998-01-09 1999-07-15 Circassia Limited Methods and compositions for desensitisation
FR2788698B1 (fr) 1999-01-27 2001-03-30 Commissariat Energie Atomique Peptides et proteines aptes a desensibiliser les sujets allergiques au venin d'abeille et compositions les contenant
ES2316632T3 (es) 2001-12-05 2009-04-16 Circassia Limited Metodos y sistemas inmunoterapeuticos.
PT1403280E (pt) 2002-09-27 2005-11-30 Biomay Prod & Handel Vacinas hipoalergenicas baseadas no alergenio ph1 p 7 de polen de capim timoteo
US7923209B2 (en) 2003-03-14 2011-04-12 Anergis, S.A. Allergen peptide fragments and use thereof
ES2425486T3 (es) 2007-05-09 2013-10-15 Circassia Limited Análisis de pronóstico para determinar la respuesta de células T a antígenos HLA y uso del mismo en el campo del trasplante de tejidos
GB0710529D0 (en) 2007-06-01 2007-07-11 Circassia Ltd Vaccine
SI2083856T1 (sl) * 2007-08-15 2011-02-28 Circassia Ltd Peptidi za desenzibilizacijo proti alergijam
US8821887B2 (en) 2008-08-15 2014-09-02 Circassia Limited T-cell antigen peptide from allergen for stimulation of IL-10 production
GB201002559D0 (en) * 2010-02-15 2010-03-31 Circassia Ltd Birch peptides for vaccine

Also Published As

Publication number Publication date
MX2012009431A (es) 2012-09-12
GB201102657D0 (en) 2011-03-30
US9017689B2 (en) 2015-04-28
AU2011214104A1 (en) 2012-09-06
CA2789353A1 (en) 2011-08-18
EA201290792A1 (ru) 2013-03-29
GB2481475B (en) 2012-09-19
GB2481475A (en) 2011-12-28
US20130243798A1 (en) 2013-09-19
AU2011214104B2 (en) 2015-05-28
IL221196A0 (en) 2012-10-31
ES2573651T3 (es) 2016-06-09
NZ602380A (en) 2014-10-31
SI2536429T1 (sl) 2016-08-31
WO2011098778A2 (en) 2011-08-18
CA3139588A1 (en) 2011-08-18
JP2016166194A (ja) 2016-09-15
JP2013519717A (ja) 2013-05-30
US20150196635A1 (en) 2015-07-16
WO2011098778A3 (en) 2011-12-15
CN102762225B (zh) 2015-05-13
HUE029138T2 (hu) 2017-02-28
HRP20160481T1 (hr) 2016-06-03
HK1165700A1 (en) 2012-10-12
CN102762225A (zh) 2012-10-31
EP2536429B1 (en) 2016-02-10
SG183198A1 (en) 2012-09-27
DK2536429T3 (en) 2016-05-23
JP5926198B2 (ja) 2016-05-25
GB201002559D0 (en) 2010-03-31
WO2011098778A8 (en) 2012-09-27
EP3056213A1 (en) 2016-08-17
PL2536429T3 (pl) 2016-09-30
EP2536429A2 (en) 2012-12-26

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