KR20120089623A - 정맥내 투여용 이부프로펜을 이용한 환자의 치료 - Google Patents

정맥내 투여용 이부프로펜을 이용한 환자의 치료 Download PDF

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Publication number
KR20120089623A
KR20120089623A KR1020127001218A KR20127001218A KR20120089623A KR 20120089623 A KR20120089623 A KR 20120089623A KR 1020127001218 A KR1020127001218 A KR 1020127001218A KR 20127001218 A KR20127001218 A KR 20127001218A KR 20120089623 A KR20120089623 A KR 20120089623A
Authority
KR
South Korea
Prior art keywords
ibuprofen
patients
dose
severe
intravenous administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1020127001218A
Other languages
English (en)
Korean (ko)
Inventor
레오 파브리브
에미 딕스 락
Original Assignee
큠버랜드 파마슈티컬즈 인코포레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US12/570,912 external-priority patent/US20110028556A1/en
Priority claimed from US12/646,499 external-priority patent/US8871810B2/en
Application filed by 큠버랜드 파마슈티컬즈 인코포레이티드 filed Critical 큠버랜드 파마슈티컬즈 인코포레이티드
Publication of KR20120089623A publication Critical patent/KR20120089623A/ko
Withdrawn legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
KR1020127001218A 2009-07-15 2010-05-25 정맥내 투여용 이부프로펜을 이용한 환자의 치료 Withdrawn KR20120089623A (ko)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US22577809P 2009-07-15 2009-07-15
US61/225,778 2009-07-15
US23034209P 2009-07-31 2009-07-31
US23032409P 2009-07-31 2009-07-31
US61/230,324 2009-07-31
US61/230,342 2009-07-31
US12/570,912 2009-09-30
US12/570,912 US20110028556A1 (en) 2009-07-31 2009-09-30 Treating critically ill patients with intravenous ibuprofen
US12/646,499 2009-12-23
US12/646,499 US8871810B2 (en) 2009-07-15 2009-12-23 Treating critically ill patients with intravenous ibuprofen
US12/699,595 US8735452B2 (en) 2009-07-15 2010-02-03 Treating patients with intravenous ibuprofen
US12/699,595 2010-02-03
PCT/US2010/036015 WO2011008347A1 (en) 2009-07-15 2010-05-25 Treating patients with intravenous ibuprofen

Publications (1)

Publication Number Publication Date
KR20120089623A true KR20120089623A (ko) 2012-08-13

Family

ID=45773652

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020127001218A Withdrawn KR20120089623A (ko) 2009-07-15 2010-05-25 정맥내 투여용 이부프로펜을 이용한 환자의 치료

Country Status (9)

Country Link
US (2) US8735452B2 (enExample)
EP (1) EP2453742A4 (enExample)
JP (1) JP5837877B2 (enExample)
KR (1) KR20120089623A (enExample)
CN (1) CN102469781A (enExample)
AU (1) AU2010274030B2 (enExample)
BR (1) BR112012000773A2 (enExample)
CA (1) CA2767971A1 (enExample)
WO (1) WO2011008347A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012523377A (ja) * 2009-03-12 2012-10-04 カンバーランド ファーマスーティカルズ インコーポレイテッド 静脈内イブプロフェンの投与
US9072661B2 (en) 2012-03-16 2015-07-07 Cumberland Pharmaceuticals Inc. Injectable ibuprofen formulation
US9072710B2 (en) 2012-03-16 2015-07-07 Cumberland Pharmaceuticals Inc. Injectable ibuprofen formulation
CN110693822A (zh) * 2019-09-29 2020-01-17 山东罗欣药业集团股份有限公司 一种布洛芬注射液及制备方法
CN111214467A (zh) * 2020-03-05 2020-06-02 南京巴傲得生物科技有限公司 吲哚布洛芬在抵抗hmgb1促炎活性中的应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1497044A (en) * 1974-03-07 1978-01-05 Prodotti Antibiotici Spa Salts of phenyl-alkanoic acids
DE2914788A1 (de) * 1979-04-11 1980-10-16 Nattermann A & Cie Parenteral applizierbare, stabile arzneimittelloesungen mit entzuendungshemmender wirkung
US4861797A (en) * 1987-10-15 1989-08-29 Oratech Pharmaceutical Development Corporation Liquid ibuprofen compositions and methods of making them
US4859704A (en) * 1987-10-15 1989-08-22 Oratech Pharmaceutical Development Corporation Water soluble ibuprofen compositions and methods of making them
US5200558A (en) * 1989-10-17 1993-04-06 Merck & Co., Inc. S(+)-ibuprofen-L-amino acid and S(+)-ibuprofen-D-amino acid as onset-hastened enhanced analgesics
IT1264857B1 (it) * 1993-06-21 1996-10-17 Zambon Spa Composizione farmaceutica liquida per uso orale contenente acido 2-(4-isobutilfenil) propionico
IT1266583B1 (it) * 1993-07-30 1997-01-09 Zambon Spa Processo per la preparazione di sali dell'acido 2-(4-isobutilfenil)- propionico
US6423746B1 (en) * 1999-07-03 2002-07-23 The William M. Yarbrough Foundation Urushiol induced contact dermatitis and method of use
US6342530B1 (en) * 2000-11-14 2002-01-29 Farmacon-Il, Llc Composition and method for parenteral administration of ibuprofen d,l- or l-lysine salt
US20040132823A1 (en) 2001-11-02 2004-07-08 Leo Pavliv Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid
DE60114249T2 (de) * 2001-11-02 2006-05-18 Cumberland Pharmaceuticals Inc., Nashville Pharmazeutische zusammensetzung mit 2-(4-isobutylphenyl) propionsäure
US6727286B2 (en) * 2001-11-02 2004-04-27 Cumberland Pharmaceuticals Inc. Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid
US8229903B2 (en) * 2002-12-19 2012-07-24 International Business Machines Corporation Suggesting data interpretations and patterns for updating policy documents
JP5345620B2 (ja) * 2007-08-15 2013-11-20 マクニール−ピーピーシー・インコーポレーテツド 即時放出及び徐放型イブプロフェンの投与法
CN101265178A (zh) * 2008-04-25 2008-09-17 北京阜康仁生物制药科技有限公司 一种右旋布洛芬的氨基酸盐及其药用组合物

Also Published As

Publication number Publication date
US20140235720A1 (en) 2014-08-21
AU2010274030B2 (en) 2015-04-23
CA2767971A1 (en) 2011-01-20
US20110028557A1 (en) 2011-02-03
US9114068B2 (en) 2015-08-25
JP2012533542A (ja) 2012-12-27
JP5837877B2 (ja) 2015-12-24
AU2010274030A1 (en) 2012-01-19
WO2011008347A1 (en) 2011-01-20
EP2453742A4 (en) 2012-09-05
CN102469781A (zh) 2012-05-23
US8735452B2 (en) 2014-05-27
BR112012000773A2 (pt) 2017-08-29
EP2453742A1 (en) 2012-05-23

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Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20120116

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid