IT1266583B1 - Processo per la preparazione di sali dell'acido 2-(4-isobutilfenil)- propionico - Google Patents

Processo per la preparazione di sali dell'acido 2-(4-isobutilfenil)- propionico

Info

Publication number
IT1266583B1
IT1266583B1 IT93MI001721A ITMI931721A IT1266583B1 IT 1266583 B1 IT1266583 B1 IT 1266583B1 IT 93MI001721 A IT93MI001721 A IT 93MI001721A IT MI931721 A ITMI931721 A IT MI931721A IT 1266583 B1 IT1266583 B1 IT 1266583B1
Authority
IT
Italy
Prior art keywords
isobutylphenyl
salts
preparation
propionic acid
propionic
Prior art date
Application number
IT93MI001721A
Other languages
English (en)
Inventor
Federico Stroppolo
Daniele Bonadeo
Annibale Gazzaniga
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Spa filed Critical Zambon Spa
Priority to IT93MI001721A priority Critical patent/IT1266583B1/it
Publication of ITMI931721A0 publication Critical patent/ITMI931721A0/it
Priority to US08/281,670 priority patent/US5463117A/en
Publication of ITMI931721A1 publication Critical patent/ITMI931721A1/it
Application granted granted Critical
Publication of IT1266583B1 publication Critical patent/IT1266583B1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/26—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41—Preparation of salts of carboxylic acids
    • C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT93MI001721A 1993-07-30 1993-07-30 Processo per la preparazione di sali dell'acido 2-(4-isobutilfenil)- propionico IT1266583B1 (it)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IT93MI001721A IT1266583B1 (it) 1993-07-30 1993-07-30 Processo per la preparazione di sali dell'acido 2-(4-isobutilfenil)- propionico
US08/281,670 US5463117A (en) 1993-07-30 1994-07-29 Process for the preparation of salts of 2-(4-isobutylphenyl)propionic acid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT93MI001721A IT1266583B1 (it) 1993-07-30 1993-07-30 Processo per la preparazione di sali dell'acido 2-(4-isobutilfenil)- propionico

Publications (3)

Publication Number Publication Date
ITMI931721A0 ITMI931721A0 (it) 1993-07-30
ITMI931721A1 ITMI931721A1 (it) 1995-01-30
IT1266583B1 true IT1266583B1 (it) 1997-01-09

Family

ID=11366737

Family Applications (1)

Application Number Title Priority Date Filing Date
IT93MI001721A IT1266583B1 (it) 1993-07-30 1993-07-30 Processo per la preparazione di sali dell'acido 2-(4-isobutilfenil)- propionico

Country Status (2)

Country Link
US (1) US5463117A (it)
IT (1) IT1266583B1 (it)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6727286B2 (en) 2001-11-02 2004-04-27 Cumberland Pharmaceuticals Inc. Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid
US20070265344A1 (en) * 2006-02-06 2007-11-15 Pharmaceutical Solutions, Inc. Non-steroidal anti-inflammatory oral powder and liquid preparations for administration to animals
WO2011001228A1 (en) * 2008-08-14 2011-01-06 Shasun Chemicals And Drugs Limited Aryl alkyl carboxylic acid salts, process for preparation and dosage forms
KR20140014350A (ko) 2009-03-12 2014-02-06 큠버랜드 파마슈티컬즈 인코포레이티드 정맥 내 투여용 이부프로펜의 투여
US8871810B2 (en) * 2009-07-15 2014-10-28 Cumberland Pharmaceuticals Inc. Treating critically ill patients with intravenous ibuprofen
US8735452B2 (en) * 2009-07-15 2014-05-27 Cumberland Pharmaceuticals Inc. Treating patients with intravenous ibuprofen
WO2011014208A1 (en) * 2009-07-31 2011-02-03 Leo Pavliv Treating critically ill patients with intravenous ibuprofen
WO2013112456A1 (en) 2012-01-24 2013-08-01 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Controlled release formulations for the induction and proliferation of blood cells
US9072661B2 (en) 2012-03-16 2015-07-07 Cumberland Pharmaceuticals Inc. Injectable ibuprofen formulation
US9072710B2 (en) 2012-03-16 2015-07-07 Cumberland Pharmaceuticals Inc. Injectable ibuprofen formulation
CA2867477C (en) 2012-03-16 2017-09-26 Cumberland Pharmaceuticals, Inc. Injectable ibuprofen formulation

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1497044A (en) * 1974-03-07 1978-01-05 Prodotti Antibiotici Spa Salts of phenyl-alkanoic acids
IT1059677B (it) * 1974-03-22 1982-06-21 Neopharmed Spa Sale di lisina ad azione terapeutica
IT1209667B (it) * 1985-11-12 1989-08-30 Zambon Spa Composizione effeverscente adattivita' analgesica.
IT1197038B (it) * 1986-08-01 1988-11-25 Zambon Spa Composizione farmaceutica ad attivita' analgesica
US5200558A (en) * 1989-10-17 1993-04-06 Merck & Co., Inc. S(+)-ibuprofen-L-amino acid and S(+)-ibuprofen-D-amino acid as onset-hastened enhanced analgesics
ATE128452T1 (de) * 1989-10-17 1995-10-15 Merck & Co Inc S(+)-ibuprofen-l-aminosäure und s(+)-ibuprofen-d- aminosäure als analgetika mit grösserem pharmakologischem potential.
US5380867A (en) * 1992-12-02 1995-01-10 Hoechst Celanese Corporation Selective precipitation of α-aryl carboxylic acid salts
US5332834A (en) * 1992-12-02 1994-07-26 Hoechst Celanese Corporation Racemization of an enantomerically enriched α-aryl carboxylic acid

Also Published As

Publication number Publication date
ITMI931721A1 (it) 1995-01-30
US5463117A (en) 1995-10-31
ITMI931721A0 (it) 1993-07-30

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Legal Events

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0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970612