CA2767971A1 - Treating patients with intravenous ibuprofen - Google Patents

Treating patients with intravenous ibuprofen Download PDF

Info

Publication number
CA2767971A1
CA2767971A1 CA2767971A CA2767971A CA2767971A1 CA 2767971 A1 CA2767971 A1 CA 2767971A1 CA 2767971 A CA2767971 A CA 2767971A CA 2767971 A CA2767971 A CA 2767971A CA 2767971 A1 CA2767971 A1 CA 2767971A1
Authority
CA
Canada
Prior art keywords
ibuprofen
patients
dose
critically ill
intravenous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2767971A
Other languages
English (en)
French (fr)
Inventor
Leo Pavliv
Amy Dix Rock
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cumberland Pharmaceuticals Inc
Original Assignee
Cumberland Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US12/570,912 external-priority patent/US20110028556A1/en
Priority claimed from US12/646,499 external-priority patent/US8871810B2/en
Application filed by Cumberland Pharmaceuticals Inc filed Critical Cumberland Pharmaceuticals Inc
Publication of CA2767971A1 publication Critical patent/CA2767971A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
CA2767971A 2009-07-15 2010-05-25 Treating patients with intravenous ibuprofen Abandoned CA2767971A1 (en)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US22577809P 2009-07-15 2009-07-15
US61/225,778 2009-07-15
US23032409P 2009-07-31 2009-07-31
US23034209P 2009-07-31 2009-07-31
US61/230,342 2009-07-31
US61/230,324 2009-07-31
US12/570,912 US20110028556A1 (en) 2009-07-31 2009-09-30 Treating critically ill patients with intravenous ibuprofen
US12/570,912 2009-09-30
US12/646,499 US8871810B2 (en) 2009-07-15 2009-12-23 Treating critically ill patients with intravenous ibuprofen
US12/646,499 2009-12-23
US12/699,595 2010-02-03
US12/699,595 US8735452B2 (en) 2009-07-15 2010-02-03 Treating patients with intravenous ibuprofen
PCT/US2010/036015 WO2011008347A1 (en) 2009-07-15 2010-05-25 Treating patients with intravenous ibuprofen

Publications (1)

Publication Number Publication Date
CA2767971A1 true CA2767971A1 (en) 2011-01-20

Family

ID=45773652

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2767971A Abandoned CA2767971A1 (en) 2009-07-15 2010-05-25 Treating patients with intravenous ibuprofen

Country Status (9)

Country Link
US (2) US8735452B2 (enExample)
EP (1) EP2453742A4 (enExample)
JP (1) JP5837877B2 (enExample)
KR (1) KR20120089623A (enExample)
CN (1) CN102469781A (enExample)
AU (1) AU2010274030B2 (enExample)
BR (1) BR112012000773A2 (enExample)
CA (1) CA2767971A1 (enExample)
WO (1) WO2011008347A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2010224063B2 (en) * 2009-03-12 2015-04-16 Cumberland Pharmaceuticals Inc Administration of intravenous ibuprofen
US9072661B2 (en) 2012-03-16 2015-07-07 Cumberland Pharmaceuticals Inc. Injectable ibuprofen formulation
US9072710B2 (en) 2012-03-16 2015-07-07 Cumberland Pharmaceuticals Inc. Injectable ibuprofen formulation
SI3996699T1 (sl) 2019-07-09 2023-10-30 Farmalider, S. A. Kombinacija ibuprofena in tramadola za lajšanje bolečine
CN110693822A (zh) * 2019-09-29 2020-01-17 山东罗欣药业集团股份有限公司 一种布洛芬注射液及制备方法
CN111214467A (zh) * 2020-03-05 2020-06-02 南京巴傲得生物科技有限公司 吲哚布洛芬在抵抗hmgb1促炎活性中的应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1497044A (en) 1974-03-07 1978-01-05 Prodotti Antibiotici Spa Salts of phenyl-alkanoic acids
DE2914788A1 (de) 1979-04-11 1980-10-16 Nattermann A & Cie Parenteral applizierbare, stabile arzneimittelloesungen mit entzuendungshemmender wirkung
US4859704A (en) 1987-10-15 1989-08-22 Oratech Pharmaceutical Development Corporation Water soluble ibuprofen compositions and methods of making them
US4861797A (en) 1987-10-15 1989-08-29 Oratech Pharmaceutical Development Corporation Liquid ibuprofen compositions and methods of making them
US5200558A (en) 1989-10-17 1993-04-06 Merck & Co., Inc. S(+)-ibuprofen-L-amino acid and S(+)-ibuprofen-D-amino acid as onset-hastened enhanced analgesics
IT1264857B1 (it) 1993-06-21 1996-10-17 Zambon Spa Composizione farmaceutica liquida per uso orale contenente acido 2-(4-isobutilfenil) propionico
IT1266583B1 (it) 1993-07-30 1997-01-09 Zambon Spa Processo per la preparazione di sali dell'acido 2-(4-isobutilfenil)- propionico
US6423746B1 (en) 1999-07-03 2002-07-23 The William M. Yarbrough Foundation Urushiol induced contact dermatitis and method of use
US6342530B1 (en) 2000-11-14 2002-01-29 Farmacon-Il, Llc Composition and method for parenteral administration of ibuprofen d,l- or l-lysine salt
US6727286B2 (en) * 2001-11-02 2004-04-27 Cumberland Pharmaceuticals Inc. Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid
US20040132823A1 (en) 2001-11-02 2004-07-08 Leo Pavliv Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid
JP5185488B2 (ja) * 2001-11-02 2013-04-17 カンバーランド ファーマシューティカルズ，インコーポレーテッド ２−（４−イソブチルフェニル）プロピオン酸の医薬組成物
US8229903B2 (en) * 2002-12-19 2012-07-24 International Business Machines Corporation Suggesting data interpretations and patterns for updating policy documents
MX2010001789A (es) 2007-08-15 2010-03-10 Mcneil Ppc Inc Regimen de dosificacion de ibuprofeno de liberacion inmediata y liberacion sostenida.
CN101265178A (zh) * 2008-04-25 2008-09-17 北京阜康仁生物制药科技有限公司 一种右旋布洛芬的氨基酸盐及其药用组合物

Also Published As

Publication number Publication date
CN102469781A (zh) 2012-05-23
US20140235720A1 (en) 2014-08-21
US20110028557A1 (en) 2011-02-03
JP2012533542A (ja) 2012-12-27
EP2453742A1 (en) 2012-05-23
KR20120089623A (ko) 2012-08-13
WO2011008347A1 (en) 2011-01-20
JP5837877B2 (ja) 2015-12-24
US9114068B2 (en) 2015-08-25
BR112012000773A2 (pt) 2017-08-29
AU2010274030B2 (en) 2015-04-23
AU2010274030A1 (en) 2012-01-19
EP2453742A4 (en) 2012-09-05
US8735452B2 (en) 2014-05-27

Similar Documents

Publication Publication Date Title
US9931311B2 (en) Treating critically ill patients with intravenous ibuprofen
US9114068B2 (en) Treating patients with intravenous ibuprofen
JP6353577B2 (ja) 組み合わせ組成物
ES2823249T3 (es) Administración de ibuprofeno por vía intravenosa
US20110028556A1 (en) Treating critically ill patients with intravenous ibuprofen
US20170290793A1 (en) Formulations for treating pain
HK1168734A (en) Treating patients with intravenous ibuprofen
MX2010004974A (es) Combinacion de un aine y un aminoacido.
HK1174493A (en) Treating critically ill patients with intravenous ibuprofen

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20150525

FZDE Discontinued

Effective date: 20171025