KR20120060201A - 기능적으로 분화된 체세포의 연장된 자기재생을 유도하는 방법 - Google Patents

기능적으로 분화된 체세포의 연장된 자기재생을 유도하는 방법 Download PDF

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Publication number
KR20120060201A
KR20120060201A KR1020127003421A KR20127003421A KR20120060201A KR 20120060201 A KR20120060201 A KR 20120060201A KR 1020127003421 A KR1020127003421 A KR 1020127003421A KR 20127003421 A KR20127003421 A KR 20127003421A KR 20120060201 A KR20120060201 A KR 20120060201A
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KR
South Korea
Prior art keywords
myc
cells
gene
group
klf
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Abandoned
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KR1020127003421A
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English (en)
Korean (ko)
Inventor
Michael Sieweke
Original Assignee
인쎄름 (엥스띠뛰 나씨오날 드 라 쌍떼 에 드 라 흐쉐르슈 메디깔)
위니베르시테 데 라 메디테란 엑스마르세이유 2
상뜨로 나쇼날 드 라 러쉐르쉐 샹띠피크
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Publication of KR20120060201A publication Critical patent/KR20120060201A/ko
Abandoned legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/17—Monocytes; Macrophages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
    • A61K40/24—Antigen-presenting cells [APC]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4242—Transcription factors, e.g. SOX or c-MYC
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
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    • A61P3/06—Antihyperlipidemics
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  • General Health & Medical Sciences (AREA)
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  • Veterinary Medicine (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Wood Science & Technology (AREA)
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  • Genetics & Genomics (AREA)
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  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Obesity (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020127003421A 2009-07-08 2010-07-08 기능적으로 분화된 체세포의 연장된 자기재생을 유도하는 방법 Abandoned KR20120060201A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09305661.2 2009-07-08
EP09305661 2009-07-08
PCT/EP2010/059843 WO2011003988A1 (en) 2009-07-08 2010-07-08 A method for inducing extended self-renewal of functionally differentiated somatic cells

Publications (1)

Publication Number Publication Date
KR20120060201A true KR20120060201A (ko) 2012-06-11

Family

ID=41128562

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020127003421A Abandoned KR20120060201A (ko) 2009-07-08 2010-07-08 기능적으로 분화된 체세포의 연장된 자기재생을 유도하는 방법

Country Status (7)

Country Link
US (1) US9175265B2 (https=)
EP (1) EP2451836A1 (https=)
JP (2) JP6091893B2 (https=)
KR (1) KR20120060201A (https=)
CA (1) CA2765504A1 (https=)
SG (1) SG177552A1 (https=)
WO (1) WO2011003988A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012043651A1 (ja) * 2010-09-30 2012-04-05 国立大学法人 熊本大学 ミエロイド系血液細胞の製造方法
WO2013134022A1 (en) * 2012-03-05 2013-09-12 Wake Forest University Health Sciences Regeneration of inner ear cells
CA2884309A1 (en) * 2012-09-07 2014-03-13 Massachusetts Eye And Ear Infirmary Methods and compositions for regenerating hair cells and/or supporting cells from differentiated cochlear cells or differentiated utricular cells by modulation of notch and cmyc activity
WO2015077498A1 (en) * 2013-11-20 2015-05-28 The University Of North Carolina At Chapel Hill Methods and compositions for treating disorders of the eye
KR102013060B1 (ko) * 2018-01-29 2019-08-21 공주대학교 산학협력단 Klf-4를 이용하는 연골세포 분화 촉진 방법
EP4570905A1 (en) * 2022-08-09 2025-06-18 Agc Inc. Method for producing proliferative macrophage-like cells (pmac)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999065910A1 (en) 1998-06-16 1999-12-23 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Fused azepinone cyclin dependent kinase inhibitors
AU2004285522A1 (en) 2003-10-28 2005-05-12 Centre National De La Recherche Scientifique Indirubin-type compounds, compositions, and methods for their use
US8552053B2 (en) 2005-12-23 2013-10-08 Centre National De La Recherche Scientifique 7-substituted indirubin-3′oximes and their applications
EP1944361A1 (en) 2007-01-11 2008-07-16 INSERM (Institut National de la Santé et de la Recherche Médicale) A method for expanding monocytes
WO2009032456A2 (en) * 2007-08-01 2009-03-12 Primegen Biotech Llc Non-viral delivery of transcription factors that reprogram human somatic cells into a stem cell-like state
AU2008297011B2 (en) 2007-08-31 2014-06-12 Whitehead Institute For Biomedical Research Wnt pathway stimulation in reprogramming somatic cells
EP2149553B1 (en) 2008-08-01 2011-10-19 Centre National de la Recherche Scientifique 3', 6-substituted indirubins and their biological applications
US20100130476A1 (en) 2008-11-12 2010-05-27 The Scripps Research Institute Compounds that induce pancreatic beta-cell expansion

Also Published As

Publication number Publication date
JP2016028592A (ja) 2016-03-03
SG177552A1 (en) 2012-03-29
EP2451836A1 (en) 2012-05-16
JP2012532592A (ja) 2012-12-20
US9175265B2 (en) 2015-11-03
WO2011003988A1 (en) 2011-01-13
CA2765504A1 (en) 2011-01-13
JP6091893B2 (ja) 2017-03-08
US20120156179A1 (en) 2012-06-21

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