KR20120002129A - 면역글로불린 단편을 이용한 제７인자（Ｆａｃｔｏｒ Ⅶａ）약물 결합체 - Google Patents
면역글로불린 단편을 이용한 제７인자（Ｆａｃｔｏｒ Ⅶａ）약물 결합체 Download PDFInfo
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- KR20120002129A KR20120002129A KR1020100062860A KR20100062860A KR20120002129A KR 20120002129 A KR20120002129 A KR 20120002129A KR 1020100062860 A KR1020100062860 A KR 1020100062860A KR 20100062860 A KR20100062860 A KR 20100062860A KR 20120002129 A KR20120002129 A KR 20120002129A
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- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
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- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
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- A61K47/6889—Conjugates wherein the antibody being the modifying agent and wherein the linker, binder or spacer confers particular properties to the conjugates, e.g. peptidic enzyme-labile linkers or acid-labile linkers, providing for an acid-labile immuno conjugate wherein the drug may be released from its antibody conjugated part in an acidic, e.g. tumoural or environment
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- C—CHEMISTRY; METALLURGY
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- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- C07—ORGANIC CHEMISTRY
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- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
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- Biophysics (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Materials For Medical Uses (AREA)
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020100062860A KR20120002129A (ko) | 2010-06-30 | 2010-06-30 | 면역글로불린 단편을 이용한 제７인자（Ｆａｃｔｏｒ Ⅶａ）약물 결합체 |
| ARP110102301A AR082032A1 (es) | 2010-06-30 | 2011-06-29 | Complejo de factor viia en el que se utiliza un fragmento de inmunoglobulina |
| US13/807,572 US20130095090A1 (en) | 2010-06-30 | 2011-06-30 | Factor viia complex using an immunoglobulin fragment |
| TW100123053A TWI443106B (zh) | 2010-06-30 | 2011-06-30 | 使用免疫球蛋白片段之ＶＩＩａ因子錯合物 |
| JP2013518254A JP2013533875A (ja) | 2010-06-30 | 2011-06-30 | 免疫グロブリン断片を用いた第７因子（ＦａｃｔｏｒＶＩＩａ）薬物結合体 |
| PCT/KR2011/004796 WO2012002745A2 (en) | 2010-06-30 | 2011-06-30 | Factor viia complex using an immunoglobulin fragment |
| EP11801151.9A EP2588142A2 (en) | 2010-06-30 | 2011-06-30 | Factor viia complex using an immunoglobulin fragment |
| CN2011800325807A CN103025358A (zh) | 2010-06-30 | 2011-06-30 | 使用免疫球蛋白片段的因子viia复合物 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020100062860A KR20120002129A (ko) | 2010-06-30 | 2010-06-30 | 면역글로불린 단편을 이용한 제７인자（Ｆａｃｔｏｒ Ⅶａ）약물 결합체 |
Publications (1)
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| KR20120002129A true KR20120002129A (ko) | 2012-01-05 |
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Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20130095090A1 (enExample) |
| EP (1) | EP2588142A2 (enExample) |
| JP (1) | JP2013533875A (enExample) |
| KR (1) | KR20120002129A (enExample) |
| CN (1) | CN103025358A (enExample) |
| AR (1) | AR082032A1 (enExample) |
| TW (1) | TWI443106B (enExample) |
| WO (1) | WO2012002745A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| KR101892687B1 (ko) | 2017-05-18 | 2018-08-28 | 세종대학교산학협력단 | 하이드라진 연료전지용 전극과 이를 포함하는 막 전극 접합체 및 연료전지 |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0406606A (pt) * | 2003-11-13 | 2005-12-06 | Hanmi Pharm Ind Co Ltd | Composição farmacêutica compreendendo uma região fc de imunoglobulina como um veìculo |
| CN104774269B (zh) * | 2013-08-16 | 2016-02-24 | 安源生物科技(上海)有限公司 | 改良型人凝血因子FVII-Fc融合蛋白及其制备方法与用途 |
| KR20160143820A (ko) * | 2014-04-11 | 2016-12-14 | 시에스엘 리미티드 | 출혈의 예방 및 치료를 위한 반감기 연장 인자 ｆｖｉｉａ 단백질 및 이의 투약 용법 |
| BR112018014870A2 (pt) * | 2016-01-21 | 2018-12-11 | Protein Dynamic Solutions Llc | método e sistema para análise de dados espectrais |
| CN111849945B (zh) * | 2019-04-25 | 2024-11-29 | 正大天晴药业集团股份有限公司 | 人凝血因子VIIa的纯化方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| RU2388460C2 (ru) * | 2003-08-14 | 2010-05-10 | Ново Нордиск Хелс Кеа Аг | Жидкая водная фармацевтическая композиция, содержащая полипептид фактора vii |
| JP2007509843A (ja) * | 2003-10-07 | 2007-04-19 | ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト | 第ＶＩＩ／ＶＩＩａ因子活性を有するハイブリッド分子 |
| BRPI0406606A (pt) * | 2003-11-13 | 2005-12-06 | Hanmi Pharm Ind Co Ltd | Composição farmacêutica compreendendo uma região fc de imunoglobulina como um veìculo |
| JP2009515508A (ja) * | 2005-08-19 | 2009-04-16 | ネオス テクノロジーズ インコーポレイテッド | グリコｐｅｇ化因子ｖｉｉおよび因子ｖｉｉａ |
| WO2007140282A1 (en) * | 2006-05-24 | 2007-12-06 | Peg Biosciences | Peg linker compounds and biologically active conjugates thereof |
| ES2531934T3 (es) * | 2006-09-01 | 2015-03-20 | Novo Nordisk Health Care Ag | Glicoproteínas modificadas |
| KR101200659B1 (ko) * | 2008-07-23 | 2012-11-12 | 한미사이언스 주식회사 | 세 말단 반응기를 갖는 비펩타이드성 중합체를 이용한 생리활성 폴리펩타이드 약물 결합체 |
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2010
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- 2011-06-30 US US13/807,572 patent/US20130095090A1/en not_active Abandoned
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- 2011-06-30 EP EP11801151.9A patent/EP2588142A2/en not_active Withdrawn
- 2011-06-30 TW TW100123053A patent/TWI443106B/zh not_active IP Right Cessation
- 2011-06-30 WO PCT/KR2011/004796 patent/WO2012002745A2/en not_active Ceased
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101892687B1 (ko) | 2017-05-18 | 2018-08-28 | 세종대학교산학협력단 | 하이드라진 연료전지용 전극과 이를 포함하는 막 전극 접합체 및 연료전지 |
Also Published As
| Publication number | Publication date |
|---|---|
| AR082032A1 (es) | 2012-11-07 |
| JP2013533875A (ja) | 2013-08-29 |
| CN103025358A (zh) | 2013-04-03 |
| WO2012002745A2 (en) | 2012-01-05 |
| TWI443106B (zh) | 2014-07-01 |
| TW201217396A (en) | 2012-05-01 |
| EP2588142A2 (en) | 2013-05-08 |
| US20130095090A1 (en) | 2013-04-18 |
| WO2012002745A3 (en) | 2012-04-26 |
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