KR20110124477A - The manufacturing method tablet become improves solubility - Google Patents

Abstract

PURPOSE: A producing method of tablets with improved solubility is provided to enable users to easily and simply intake the tablets by containing starch, and to improve the palatability of the users. CONSTITUTION: A producing method of tablets with improved solubility comprises the following steps: powdering one composition selected from fruits, medical herbs, or glucose by freeze-drying or spray-drying; mixing 89.5-93.5wt% of glucose powder, 0.5-1wt% of starch syrup, 1.5-2.5wt% of citric acid, 1.5-2wt% of flavoring agent, 1.5-3wt% of corn starch, and 1.5-2wt% of sucrose fatty acid ester, and stirring the mixture for 30 minutes; granulating the mixture into granules having the size of 0.5-4mm; aging the granules at 20-25 deg for 12 hours in an aging chamber; drying the aged granules at 60 deg C for 1 hour; assorting the dried granules, and mixing the granules with a lubricant; and molding the granules with a tableting machine, and packing the obtained tablets.

Description

The manufacturing method tablet become improves solubility

The present invention relates to a method for producing a tablet having good solubility by mixing starch in glucose powder used for edible, and more particularly, by selecting a sugar consisting of glucose, fructose and the like, mixing the starch and stirring the granules in a granulator state. Method for manufacturing tablets with improved solubility that is formed into tablet candy by molding, drying, screening to uniform size, screening metal detector, mixing lubricant, tableting, and screening to uniform size. will be.

In general, vitamins, nutrients, candy and the like in the form of tablets to facilitate the easy to eat.

That is, when the health food is prepared in the form of liquid, granules, not only have inconveniences for consumers when they are orally administered, but also have inconveniences when carrying out when they go out.

Therefore, it is common to take tablets with uncomfortable foods. Conventional tablets do not melt easily in the mouth, so bite the teeth, or have to discomfort in the mouth until melted.

Looking at the prior art in this field, "Tablet-type vitamin and calcium combination therapy and its preparation method and use as a unit herbal formulation" of Patent No. 0373393 is a combination therapy of calcium, the tablet of the herbal formulation suitable for chewing At least one first dry and wet binder in an amount necessary for synergy, and at least one diluent, at least one second binder, and at least one lubricant associated therewith, the diluent and the second binder At least one of them is a polyol-type sweetener, and the combination therapy has been disclosed in which the ratio of calcium to vitamin D is expressed in mg value of calcium element per IU of vitamin D.

The prior art relates to a combination therapy, it can be seen that the herbal medicines are formed in a tablet suitable for chewing. However, when the tablet is manufactured by mixing a wet binder and a dry binder into a tablet and then drying the tablet, the tablet is hardened in a molding and drying process, and thus, the tablet is not easily dissolved.

The present invention is to solve the above problems as the main component and the additive material in the form of granules, and then mixed and dried to make the moisture content of 1 ~ 1.5% and then by molding it into a tablet using a tableting machine Regardless of the type, it is easy to take, and the tablet is easily dissolved by saliva in the mouth, so that the absorption is quickened by the body, and the nutrients of the tablet candy mainly composed of glucose or vitamins are absorbed into the body. The present invention relates to a tablet manufacturing method with improved solubility for the purpose of easily taking a dietary supplement.

The present invention relates to a tablet manufacturing method having good solubility by mixing starch with glucose used for food. In particular, in order to prepare tablets, the main ingredients of glucose and sugar alcohols, syrup, citric acid, corn starch, flavorings, pigments, and lubricants as additives to form tablets with good solubility so that they can be dissolved quickly. It is. The tablet of the present invention molded as described above is to provide a health supplement food that is easy to take as well as candy. In other words, health foods such as blueberries, dandelions, vitamins, thorny ginseng, ganoderma lucidum and red ginseng, which are functional foods, are first made into granules, and then made into tablets with good solubility and provided to consumers by providing them with convenient solubility. It is to provide a tablet manufacturing method improved solubility to take a dietary supplement.

The present invention has a convenient effect by containing starch when preparing a tablet to improve the solubility, in particular, by taking a dietary supplement prepared by taking X, pill, etc. made with a good solubility tablet candy, both young and old Has the effect that can be taken easily and easily without rejection.

In particular, the tablet of the present invention is improved in solubility and easy to take, as well as the usual tablet candy, as well as herbal medicine candy, blueberry candy, dietary supplement candy, vitamin candy and the like to supply to consumers with weak stomach, Children who do not want to take medicine can easily take it.

1 is a tablet manufacturing process of the present invention.
Figure 2 is an experimental photograph prepared for testing the starch-containing tablets and tablets containing no starch of the present invention.
Figure 3 is an experimental photograph showing a state in which the starch-containing tablet and starch-containing tablet of the present invention dissolved for 48 minutes to dissolve.
Figure 4 is a photograph of a 12-minute stirring experiment of the tablet containing the starch of the present invention.
Figure 5 is a photograph of a 12-minute stirring experiment of the tablet containing no starch of the present invention.

Hereinafter, an embodiment of the present invention will be described in detail.

Powdering and milling the composition of any one of fruits, berries, medicinal herbs and glucose by screening, freeze-drying or spray-drying;

Glucose powdered in the form of milling 89.5-93.5%, starch syrup 05-1.0%, citric acid 1.5-2.5%, flavor 1.5-2.0%, corn starch 1.5-3%, sucrose fatty acid ester 1.5-2.0% Mixing the% and stirring it for 30 minutes to mix the water content to 4.5 to 5%;

Preparing the mixed mixture into granules having a size of 0.5 to 4 mm through a granulator;

Aging the prepared granules in a aging chamber at a temperature of 20-25 ° C. and a humidity of 45 ± 5% for 12 hours;

Drying the aged granules in a dryer at a temperature of 60 ° C. for 1 hour;

Detecting the dried granules in a size of 1 to 3 mm using a sorting machine and using a metal detector;

Mixing a lubricant (emulsifier) to the granules detected by the metal detector at 40 rpm for 5 minutes;

Shaping the tablet with the tablets of the granules mixed with the lubricant;

The tablet is manufactured by screening and packaging the molded tablet to a uniform size.

When explaining the embodiment of the tablet manufacturing process of the present invention prepared as described in detail as follows.

First step: milling the main composition

There are various kinds of materials for preparing the tablet of the present invention, such as fruit, fruit, medicinal herbs, glucose, etc., and the powder is powdered by freeze drying or spray drying.

That is, fruits, red ginseng, ganoderma lucidum, medicinal herbs, etc. are extracted and powdered by freeze drying or spray drying. In this case, the freeze-drying or spray-drying method may be lost in the cost and powdering process specific, but the method of powdering can be selected by the manufacturer as needed, freeze-drying or spray drying is conventional It is using the method performed by.

In addition, glucose in the composition of the present invention can be used to purchase a powdered product.

Therefore, in the embodiment of the present invention will be described with glucose as the main raw material.

Second Process: Mixing Cast and Additives

Glucose powdered in the form of milling 89.5-93.5%, starch syrup 05-1.0%, citric acid 1.5-2.5%, flavor 1.5-2.0%, corn starch 1.5-3%, sucrose fatty acid ester 1.5-2.0% % Is added to the stirrer and mixed, followed by stirring for 30 minutes to mix to 4.5 to 5% moisture content.

At this time, mixing and mixing in the stirrer may be mixed and stirred all at once, but due to the nature of the composition, powdered glucose is added to the stirrer and dissolved in water, citric acid, starch syrup, spices and mixed for 5 minutes and then corn starch Mix for 25 minutes to make the moisture content 4.5-5%. At this time, the heater is installed in the stirrer and the water is evaporated while stirring to check with a tester to complete the stirring when the water content is 4.5-5%.

Third Step: Granulation Step

The mixed mixture is placed in a granulator to prepare granules of 0.5 to 4 mm in size.

At this time, the granulation machine takes 15 to 20 minutes to granulate, and the size of the granulated granules is 0.5 to 4 mm as the granulator is rotated.

Fourth Process: Aging and Drying

The granules prepared above are aged for 12 hours in a aging chamber with a temperature of 20-25 ° C. and a humidity of 45 ± 5%. At this time, the granules are stabilized in the aging process.

When aging is done as described above, the granules are dried in a dryer at a temperature of 60 ° C. for 1 hour.

Granules matured in the drying process can be naturally dried, but drying in a short time using a dryer in order to increase the efficiency of the work because it takes a lot of drying time if the natural drying.

5th process: screening process and metal detection

The dried granules are selected using a sorting machine in a size of 1 to 3 mm. Since the granules formed in the granulator are formed to have a size of 0.5 to 4 mm, the granules are sorted to a size of 1 to 3 mm using a sorting machine to uniformize them.

The granules selected as described above are detected by a metal component using a metal detector composed of magnets or electromagnets.

While manufacturing granules, the hygiene management and external foreign matters are thoroughly blocked, so that the preparation is made, but the food is finally selected using a metal detector to detect the metal.

Step 6: Glidant Blending and Tablet Molding

A lubricant (emulsifier) is mixed with the granules detected by the metal detector and mixed at 40 rpm for 5 minutes. In the present step, the step of mixing the emulsifier is carried out in the same manner as in the conventional method for producing a tablet.

The granules in which the lubricant is mixed are molded into tablets using a separate tableting machine.

The tableting machine performed by this fixing is also shape | molding the tablet using what is normally used.

Process 7: sorting and packaging

The molded tablet is screened into a product having a uniform shape and size by selecting poorly molded or broken product, and then packaging the tablet to a predetermined standard and providing the same to a consumer.

Referring to the embodiment of the present invention manufactured as described above are as follows.

≪ Example 1 >

1) composition

Prepare 91.61 wt% glucose, 0.9161 wt% starch syrup, 2.1070 wt% citric acid, 1.6118 wt% flavoring, 2.2903 wt% cornstarch, 1.4648 wt% sucrose fatty acid ester.

2) mixing and stirring

According to the manufacturing process, the composition is added to the stirrer and mixed, but the starch is preferably put in the last because of the nature, the metered glucose powder is first put into the stirrer.

 Citric acid, syrup, flavoring, sucrose fatty acid ester dissolved in water was added to the added glucose powder, and stirred for 5 minutes, and then cornstarch was added and stirred for about 25 minutes.

3) The mixture mixed in the stirrer is put into a granulator and granulation is performed.

4) The granules granulated in the granulator are aged in a aging room for 12 hours.

5) The aged granules are dried in a drier at a temperature of 60 ° C. for 1 hour.

6) The dried granules are sorted through a sorting machine and then the metal particles are removed from the detector.

7) Mix the lubricant to the dried granules. At this time, the fragrance may be further mixed as needed.

8) The granules mixed with the lubricant are put into a tablet press and molded into a tablet.

9) The molded tablet is packaged after screening inspection.

The tablet prepared as above obtained a product having a weight of 0.7 g / ea and a hardness of 13 kg / mm 2.

<Comparative Example>

1) Composition

93.903% glucose, 0.9161% starch syrup, 2.1070% citric acid, 1.6118% fragrance, 1.4648% sucrose fatty acid ester, and the tablet was molded in the same process as described above. At this time, the starch is not mixed.

In the comparative example of this process, a product having a weight of 0.7 g / ea and a hardness of 13 kg / mm 2 was prepared to prepare under the same conditions as the tablet containing the starch among the molded tablets.

A tablet sample containing the starch prepared in Example 1 and a tablet sample containing no starch prepared in Comparative Example were prepared.

Since the tablet of the present invention is to provide a tablet with improved solubility, it was prepared as follows to carry out the experiment.

Experiment 1

Preparation: Two beakers, general purified water, three tablets containing starch prepared in Example 1 and three tablets containing no starch prepared in Comparative Example were prepared (see FIG. 2).

Two prepared beakers contained 50 kPa of water (water temperature of 20 ° C), and one starch-containing tablet and one starch-containing tablet were added to each beaker. 45 minutes after each tablet was added, starch-containing tablets were completely dissolved, but beaker-free tablets of beakers were about 1/3 dissolved and much less soluble than starch-containing tablets. (See Figure 3).

 Experiment 2

In this experiment, two transparent containers were prepared as a stirring experiment by a hot plate, and purified water having the same temperature was added to each transparent container in the same amount. In one transparent container, three tablets containing starch were added and the other transparent The container contained three tablets containing no starch.

Put the tablet in each transparent container as described above was stirred for 12 minutes.

At this time, the tablet in the transparent container containing starch was completely dissolved, but the tablet of the transparent container containing no starch could be confirmed to remain as the size grain of 1/3 conductivity at the initial size. It was found that the tablets were completely dissolved in 12 minutes, and the tablets containing no starch remained as small grains (see Figs. 4 and 5).

As can be seen from the above experiments, ① products containing starch have better solubility in aqueous solution at room temperature than products containing no starch, and ② products containing starch have better solubility in lukewarm water than products containing no starch. , ③ It can be seen from the above experiment that the product containing starch has the effect of texture as the solubility in the oral cavity is increased.

   As can be seen from the above experiments, it was confirmed that the tablet containing the starch of the present invention was superior in solubility compared to the tablet containing no starch.

Therefore, the present invention has the advantage of easy dissolution due to the rapid dissolution of the tablet by containing starch during the preparation of glucose-based tablets, fruit-based tablets, functional foods as a main ingredient tablets.

As described above, the tablet of the present invention has improved solubility and is easy to take, as well as conventional tablet candy, as well as herbal medicine candy, blueberry candy, dietary supplement candy, vitamin candy, etc. Children who do not want to take medicine can easily take it.

In addition, it has a feature that can be easily taken at home, office, school, travel, etc. by manufacturing a variety of dietary supplements with a tablet.

The tablet of the present invention carried out as described above is 89.5-93.5% by weight of functional foods consisting of one or two or more of red ginseng, thorny ginseng, dandelion, vitamins, blueberries, Chinese medicine powdered in the form of milling, 05-1.0% by weight of starch syrup. , 1.5 to 2.5 wt% citric acid, 1.5 to 2.0 wt% fragrance, 1.5 to 3 wt% corn starch, characterized in that the composition is composed of 1.5 to 2.0 wt% sucrose fatty acid ester. The functional food can be powdered by conventional methods.

Brief description of the accompanying drawings of the present invention as follows.

1 is a process chart of the tablet manufacturing process of the present invention, showing a step-by-step process chart from powder to granules and tablet molding to produce a tablet containing the starch of the present invention.

FIG. 2 is an experimental photograph prepared for experimenting a starch-containing tablet and a starch-free tablet of the present invention, showing a state prepared for solubility testing of a tablet containing starch and a tablet containing no starch.

FIG. 3 is an experimental photograph showing a state in which a starch-containing tablet and a starch-containing tablet are dissolved for 48 minutes, and dissolved according to the present invention, and a tablet containing starch and a tablet containing no starch to test solubility. Starch-containing tablets took 48 minutes to dissolve naturally in the same amount of water and temperature, while starch-free starches were 1 / 3-conductive dissolved and 2/3 of their original size remained. It can be seen that there is. Therefore, it can be seen that the tablet containing the starch is better dissolved even when left untreated as compared to the tablet containing no starch.

Figure 4 is a photograph of a 12-minute stirring experiment of the tablet containing the starch of the present invention, Figure 5 is a photograph of a 12-minute stirring experiment of the tablet containing no starch of the present invention, which is a transparent of the same size In each transparent container under the same water and the same temperature conditions, the container containing starch was contained in one container and the tablet containing no starch in another container was continuously stirred using a stick. Results The starch-containing tablets were completely dissolved at 12 minutes from the start of agitation, while the tablets containing no starch remained 1/3 of the size.

As can be seen in the above experiment, it can be seen that the tablet containing starch is superior in solubility to the tablet containing no starch.

Therefore, the tablet of the present invention is characterized by being able to provide convenience of taking by providing a tablet candy by applying to a variety of food.

Claims (3)

Powdering and milling the composition of any one of fruits, berries, medicinal herbs and glucose by screening, freeze-drying or spray-drying;
Glucose powdered in the form of milling 89.5-93.5%, starch syrup 05-1.0%, citric acid 1.5-2.5%, flavor 1.5-2.0%, corn starch 1.5-3%, sucrose fatty acid ester 1.5-2.0% Mixing the% and stirring it for 30 minutes to mix the water content to 4.5 to 5%;
Preparing the mixed mixture into granules having a size of 0.5 to 4 mm through a granulator;
Aging the prepared granules in a aging chamber at a temperature of 20-25 ° C. and a humidity of 45 ± 5% for 12 hours;
Drying the aged granules in a dryer at a temperature of 60 ° C. for 1 hour;
Detecting the dried granules in a size of 1 to 3 mm using a sorting machine and using a metal detector;
Mixing a lubricant (emulsifier) to the granules detected by the metal detector at 40 rpm for 5 minutes;
Shaping the tablet with the tablets of the granules mixed with the lubricant;
Solubility improved tablet manufacturing method characterized in that it is produced by the step of sorting and packaging the molded tablet in a uniform size. Tablets are powdered in the form of milled glucose 89.5-93.5%, starch syrup 05-1.0%, citric acid 1.5-2.5%, flavor 1.5-2.0%, corn starch 1.5-3%, sucrose fatty acid ester 1.5-2.0 Solubility improved tablet, characterized in that the composition by weight. Tablets are powdered in the form of milled red ginseng, brambles, dandelions, vitamins, blueberries, 89.5-93.5% by weight of functional foods consisting of one or more of Chinese medicine, 05-1.0% by weight syrup, 1.5-2.5% by weight citric acid , Fragrance 1.5 to 2.0% by weight, corn starch 1.5 to 3% by weight, sucrose fatty acid ester 1.5 to 2.0% by weight composition, characterized in that the improved solubility.

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