KR20110081161A - 루푸스의 치료, 진단 및 모니터링 방법 - Google Patents

루푸스의 치료, 진단 및 모니터링 방법 Download PDF

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KR20110081161A
KR20110081161A KR1020117006867A KR20117006867A KR20110081161A KR 20110081161 A KR20110081161 A KR 20110081161A KR 1020117006867 A KR1020117006867 A KR 1020117006867A KR 20117006867 A KR20117006867 A KR 20117006867A KR 20110081161 A KR20110081161 A KR 20110081161A
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South Korea
Prior art keywords
lupus
subject
loci
mutation
locus
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English (en)
Korean (ko)
Inventor
티모시 더블유. 버렌스
로버트 알. 그래햄
제프리 홈
워드 에이. 오트만
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제넨테크, 인크.
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Withdrawn legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/112Disease subtyping, staging or classification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/136Screening for pharmacological compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
KR1020117006867A 2008-09-26 2009-09-25 루푸스의 치료, 진단 및 모니터링 방법 Withdrawn KR20110081161A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10065908P 2008-09-26 2008-09-26
US61/100,659 2008-09-26

Publications (1)

Publication Number Publication Date
KR20110081161A true KR20110081161A (ko) 2011-07-13

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ID=42060417

Family Applications (1)

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KR1020117006867A Withdrawn KR20110081161A (ko) 2008-09-26 2009-09-25 루푸스의 치료, 진단 및 모니터링 방법

Country Status (11)

Country Link
US (1) US20100099101A1 (enExample)
EP (1) EP2344674A4 (enExample)
JP (1) JP2012503985A (enExample)
KR (1) KR20110081161A (enExample)
CN (1) CN102224258A (enExample)
AU (1) AU2009296393A1 (enExample)
BR (1) BRPI0913778A2 (enExample)
CA (1) CA2736373A1 (enExample)
IL (1) IL211462A0 (enExample)
MX (1) MX2011003273A (enExample)
WO (1) WO2010036960A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014058254A1 (ko) * 2012-10-10 2014-04-17 가톨릭대학교 산학협력단 1q25.1(RABGAP1L) 위치, 6P21.32 (C4) 위치 및 10q21.3위치의 DNA 복제 수 변이 검출용 프라이머를 포함하는 전신성 홍반성 루푸스 발병 위험도 예측용 조성물
KR101491214B1 (ko) * 2012-10-10 2015-02-06 가톨릭대학교 산학협력단 1q25.1(RABGAP1L) 위치, 6p21.32 (C4) 위치 및 10q21.3위치의 DNA 복제 수 변이 검출용 프라이머를 포함하는 전신성 홍반성 루푸스 발병 위험도 예측용 조성물

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108753946A (zh) * 2007-05-21 2018-11-06 健泰科生物技术公司 用于鉴定和治疗狼疮的方法和组合物
BR112012007778A2 (pt) * 2009-10-07 2020-08-11 Genentech, Inc. método para identificar lúpus, método para avaliar se um sujeito está em risco de desenvolver lúpus, medicamentos para tratar uma condição de lupus, método e usos de um agente terapêutico.
LT2496691T (lt) 2009-11-02 2017-06-12 University Of Washington Terapinės nukleazės kompozicijos ir būdai
CN102465170A (zh) * 2010-11-05 2012-05-23 复旦大学附属华山医院 一种检测bank1基因单核苷酸多态性的方法
CA2827102A1 (en) * 2011-02-10 2012-08-16 Genqual Corporation Methods of prognosing and administering treatment for inflammatory disorders
HRP20180564T1 (hr) 2011-04-29 2018-06-01 University of Washington, UW Center for Commercialization Terapijski pripravci nukleaze i postupci
CN102360016A (zh) * 2011-07-21 2012-02-22 南京工业大学 流式微球法对SLE的Sm-RNP抗体检测试剂盒的制备
HK1211602A1 (en) * 2012-10-08 2016-05-27 F. Hoffmann-La Roche Ag Cell penetrating peptides which bind irf5
JP6400604B2 (ja) * 2013-02-08 2018-10-03 アレゲーニー・シンガー リサーチ インスティチュート プレループス診断用バイオマーカーとしての細胞結合性補体活性産物
US20140278133A1 (en) * 2013-03-15 2014-09-18 Advanced Throughput, Inc. Systems and methods for disease associated human genomic variant analysis and reporting
CN103397103B (zh) * 2013-08-26 2016-04-20 中国人民解放军第三军医大学第三附属医院 一种检测socs家族基因标签单核甘酸多态性位点的方法及试剂盒
EP3063275B1 (en) 2013-10-31 2019-09-25 Resolve Therapeutics, LLC Therapeutic nuclease-albumin fusions and methods
EP2886140A1 (en) 2013-12-17 2015-06-24 University of Limerick An apparatus for the extracorporeal treatment of blood
US20170269075A1 (en) * 2014-05-12 2017-09-21 Biogen Ma Inc. Biomarkers predictive of lupus progression and uses thereof
DK3478830T3 (da) 2016-07-01 2024-05-21 Resolve Therapeutics Llc Optimerede binucleasefusioner og metoder
MX2020002070A (es) 2017-08-22 2020-03-24 Sanabio Llc Receptores solubles de interferon y usos de los mismos.
US20230123898A1 (en) * 2021-10-18 2023-04-20 Karsten Manufacturing Corporation Golf club sensor housing

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7022476B2 (en) * 2002-02-26 2006-04-04 New York Society For Ruptured And Crippled Maintaining The Hospital For Special Surgery Human FcγRIIB gene polymorphisms for assessing development of systemic lupus erythematosus and compositions for use thereof
US20070269827A1 (en) * 2006-05-18 2007-11-22 Oklahoma Medical Research Foundation Predicting and Diagnosing Patients With Autoimmune Disease
CN108753946A (zh) * 2007-05-21 2018-11-06 健泰科生物技术公司 用于鉴定和治疗狼疮的方法和组合物
CA2749869A1 (en) * 2009-03-03 2010-09-10 Merck Serono S.A. Bank1 related snps and sle and/or ms susceptibility

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014058254A1 (ko) * 2012-10-10 2014-04-17 가톨릭대학교 산학협력단 1q25.1(RABGAP1L) 위치, 6P21.32 (C4) 위치 및 10q21.3위치의 DNA 복제 수 변이 검출용 프라이머를 포함하는 전신성 홍반성 루푸스 발병 위험도 예측용 조성물
KR101491214B1 (ko) * 2012-10-10 2015-02-06 가톨릭대학교 산학협력단 1q25.1(RABGAP1L) 위치, 6p21.32 (C4) 위치 및 10q21.3위치의 DNA 복제 수 변이 검출용 프라이머를 포함하는 전신성 홍반성 루푸스 발병 위험도 예측용 조성물

Also Published As

Publication number Publication date
CA2736373A1 (en) 2010-04-01
BRPI0913778A2 (pt) 2015-10-20
WO2010036960A2 (en) 2010-04-01
WO2010036960A8 (en) 2011-04-28
CN102224258A (zh) 2011-10-19
IL211462A0 (en) 2011-05-31
US20100099101A1 (en) 2010-04-22
JP2012503985A (ja) 2012-02-16
AU2009296393A1 (en) 2010-04-01
EP2344674A2 (en) 2011-07-20
EP2344674A4 (en) 2012-11-07
MX2011003273A (es) 2011-04-28
WO2010036960A3 (en) 2010-09-30

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PA0105 International application

Patent event date: 20110325

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid