JP2012503985A - ループスの治療、診断、モニタリング方法 - Google Patents

ループスの治療、診断、モニタリング方法 Download PDF

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JP2012503985A
JP2012503985A JP2011529281A JP2011529281A JP2012503985A JP 2012503985 A JP2012503985 A JP 2012503985A JP 2011529281 A JP2011529281 A JP 2011529281A JP 2011529281 A JP2011529281 A JP 2011529281A JP 2012503985 A JP2012503985 A JP 2012503985A
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lupus
locus
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JP2012503985A5 (enExample
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ティモシー ダブリュ. ベーレンス,
ロバート アール. グラハム,
ジェフリー ホム,
ワード エー. オートマン,
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ジェネンテック, インコーポレイテッド
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15Medicinal preparations ; Physical properties thereof, e.g. dissolubility
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    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q2600/00Oligonucleotides characterized by their use
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    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

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  • Health & Medical Sciences (AREA)
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  • Biotechnology (AREA)
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  • General Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2011529281A 2008-09-26 2009-09-25 ループスの治療、診断、モニタリング方法 Pending JP2012503985A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10065908P 2008-09-26 2008-09-26
US61/100,659 2008-09-26
PCT/US2009/058478 WO2010036960A2 (en) 2008-09-26 2009-09-25 Methods for treating, diagnosing, and monitoring lupus

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JP2012503985A true JP2012503985A (ja) 2012-02-16
JP2012503985A5 JP2012503985A5 (enExample) 2012-11-15

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JP2011529281A Pending JP2012503985A (ja) 2008-09-26 2009-09-25 ループスの治療、診断、モニタリング方法

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US (1) US20100099101A1 (enExample)
EP (1) EP2344674A4 (enExample)
JP (1) JP2012503985A (enExample)
KR (1) KR20110081161A (enExample)
CN (1) CN102224258A (enExample)
AU (1) AU2009296393A1 (enExample)
BR (1) BRPI0913778A2 (enExample)
CA (1) CA2736373A1 (enExample)
IL (1) IL211462A0 (enExample)
MX (1) MX2011003273A (enExample)
WO (1) WO2010036960A2 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008144761A2 (en) * 2007-05-21 2008-11-27 Genentech, Inc. Methods and compositions for identifying and treating lupus
US20130034544A1 (en) 2009-10-07 2013-02-07 Genentech, Inc. Methods for treating, diagnosing, and monitoring lupus
MX341084B (es) 2009-11-02 2016-08-05 Univ Washington Composiciones de nucleasas terapéuticas y métodos.
CN102465170A (zh) * 2010-11-05 2012-05-23 复旦大学附属华山医院 一种检测bank1基因单核苷酸多态性的方法
WO2012109427A1 (en) * 2011-02-10 2012-08-16 Genqual Corporation Methods of prognosing and administering treatment for inflammatory disorders
PE20141172A1 (es) * 2011-04-29 2014-09-22 Univ Washington Composiciones de nucleasa terapeuticas y metodos
CN102360016A (zh) * 2011-07-21 2012-02-22 南京工业大学 流式微球法对SLE的Sm-RNP抗体检测试剂盒的制备
MX2015004145A (es) * 2012-10-08 2015-07-06 Hoffmann La Roche Peptidos de penetracion celular que se unen a factor regulador de interferon 5.
WO2014058254A1 (ko) * 2012-10-10 2014-04-17 가톨릭대학교 산학협력단 1q25.1(RABGAP1L) 위치, 6P21.32 (C4) 위치 및 10q21.3위치의 DNA 복제 수 변이 검출용 프라이머를 포함하는 전신성 홍반성 루푸스 발병 위험도 예측용 조성물
KR101491214B1 (ko) * 2012-10-10 2015-02-06 가톨릭대학교 산학협력단 1q25.1(RABGAP1L) 위치, 6p21.32 (C4) 위치 및 10q21.3위치의 DNA 복제 수 변이 검출용 프라이머를 포함하는 전신성 홍반성 루푸스 발병 위험도 예측용 조성물
CN105051210B (zh) * 2013-02-08 2020-07-28 阿勒格尼-辛格研究所 细胞结合的补体激活产物作为狼疮前期的诊断性生物标志物
US20140278133A1 (en) * 2013-03-15 2014-09-18 Advanced Throughput, Inc. Systems and methods for disease associated human genomic variant analysis and reporting
CN103397103B (zh) * 2013-08-26 2016-04-20 中国人民解放军第三军医大学第三附属医院 一种检测socs家族基因标签单核甘酸多态性位点的方法及试剂盒
WO2015066550A1 (en) 2013-10-31 2015-05-07 Resolve Therapeutics, Llc Therapeutic nuclease-albumin fusions and methods
EP2886140A1 (en) 2013-12-17 2015-06-24 University of Limerick An apparatus for the extracorporeal treatment of blood
WO2015175424A1 (en) * 2014-05-12 2015-11-19 Biogen Ma Inc. Biomarkers predictive of lupus progression and uses thereof
CN109790526A (zh) 2016-07-01 2019-05-21 分解治疗有限责任公司 优化的二核酸酶融合体和方法
KR102777015B1 (ko) 2017-08-22 2025-03-10 사나바이오, 엘엘씨 가용성 인터페론 수용체 및 그의 용도
JP2024536558A (ja) * 2021-10-18 2024-10-04 カーステン マニュファクチュアリング コーポレーション ゴルフクラブセンサハウジング

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7022476B2 (en) * 2002-02-26 2006-04-04 New York Society For Ruptured And Crippled Maintaining The Hospital For Special Surgery Human FcγRIIB gene polymorphisms for assessing development of systemic lupus erythematosus and compositions for use thereof
US20070269827A1 (en) * 2006-05-18 2007-11-22 Oklahoma Medical Research Foundation Predicting and Diagnosing Patients With Autoimmune Disease
WO2008144761A2 (en) * 2007-05-21 2008-11-27 Genentech, Inc. Methods and compositions for identifying and treating lupus
CA2749869A1 (en) * 2009-03-03 2010-09-10 Merck Serono S.A. Bank1 related snps and sle and/or ms susceptibility

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US20100099101A1 (en) 2010-04-22
CA2736373A1 (en) 2010-04-01
EP2344674A4 (en) 2012-11-07
BRPI0913778A2 (pt) 2015-10-20
WO2010036960A8 (en) 2011-04-28
AU2009296393A1 (en) 2010-04-01
KR20110081161A (ko) 2011-07-13
IL211462A0 (en) 2011-05-31
MX2011003273A (es) 2011-04-28
WO2010036960A3 (en) 2010-09-30
CN102224258A (zh) 2011-10-19
EP2344674A2 (en) 2011-07-20
WO2010036960A2 (en) 2010-04-01

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