JP2012503985A - ループスの治療、診断、モニタリング方法 - Google Patents

ループスの治療、診断、モニタリング方法 Download PDF

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JP2012503985A
JP2012503985A JP2011529281A JP2011529281A JP2012503985A JP 2012503985 A JP2012503985 A JP 2012503985A JP 2011529281 A JP2011529281 A JP 2011529281A JP 2011529281 A JP2011529281 A JP 2011529281A JP 2012503985 A JP2012503985 A JP 2012503985A
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lupus
locus
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JP2012503985A5 (enExample
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ティモシー ダブリュ. ベーレンス,
ロバート アール. グラハム,
ジェフリー ホム,
ワード エー. オートマン,
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ジェネンテック, インコーポレイテッド
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Transplantation (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2011529281A 2008-09-26 2009-09-25 ループスの治療、診断、モニタリング方法 Pending JP2012503985A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10065908P 2008-09-26 2008-09-26
US61/100,659 2008-09-26
PCT/US2009/058478 WO2010036960A2 (en) 2008-09-26 2009-09-25 Methods for treating, diagnosing, and monitoring lupus

Publications (2)

Publication Number Publication Date
JP2012503985A true JP2012503985A (ja) 2012-02-16
JP2012503985A5 JP2012503985A5 (enExample) 2012-11-15

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JP2011529281A Pending JP2012503985A (ja) 2008-09-26 2009-09-25 ループスの治療、診断、モニタリング方法

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US (1) US20100099101A1 (enExample)
EP (1) EP2344674A4 (enExample)
JP (1) JP2012503985A (enExample)
KR (1) KR20110081161A (enExample)
CN (1) CN102224258A (enExample)
AU (1) AU2009296393A1 (enExample)
BR (1) BRPI0913778A2 (enExample)
CA (1) CA2736373A1 (enExample)
IL (1) IL211462A0 (enExample)
MX (1) MX2011003273A (enExample)
WO (1) WO2010036960A2 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103298950B (zh) * 2007-05-21 2015-01-21 健泰科生物技术公司 用于鉴定和治疗狼疮的方法和组合物
EP2486152B1 (en) 2009-10-07 2017-12-06 F. Hoffmann-La Roche AG Methods for diagnosing lupus
HUE041426T2 (hu) 2009-11-02 2019-05-28 Univ Washington Terápiás nukleáz-készítmények és eljárások
CN102465170A (zh) * 2010-11-05 2012-05-23 复旦大学附属华山医院 一种检测bank1基因单核苷酸多态性的方法
BR112013020498A2 (pt) * 2011-02-10 2016-08-09 Genqual Corp método para determinar a capacidade de resposta a inibidores e para tratamento de um sujeito
CA2834626A1 (en) 2011-04-29 2012-11-01 University Of Washington Therapeutic nuclease compositions and methods
CN102360016A (zh) * 2011-07-21 2012-02-22 南京工业大学 流式微球法对SLE的Sm-RNP抗体检测试剂盒的制备
WO2014056813A1 (en) * 2012-10-08 2014-04-17 F. Hoffmann-La Roche Ag Cell penetrating peptides which bind irf5
WO2014058254A1 (ko) * 2012-10-10 2014-04-17 가톨릭대학교 산학협력단 1q25.1(RABGAP1L) 위치, 6P21.32 (C4) 위치 및 10q21.3위치의 DNA 복제 수 변이 검출용 프라이머를 포함하는 전신성 홍반성 루푸스 발병 위험도 예측용 조성물
KR101491214B1 (ko) * 2012-10-10 2015-02-06 가톨릭대학교 산학협력단 1q25.1(RABGAP1L) 위치, 6p21.32 (C4) 위치 및 10q21.3위치의 DNA 복제 수 변이 검출용 프라이머를 포함하는 전신성 홍반성 루푸스 발병 위험도 예측용 조성물
RU2019103573A (ru) * 2013-02-08 2019-03-15 Аллегени-Сингер Рисерч Инститьют Клеточно-связанные продукты активации комплемента в качестве диагностических биомаркеров волчанки в доклинической стадии
US20140278133A1 (en) * 2013-03-15 2014-09-18 Advanced Throughput, Inc. Systems and methods for disease associated human genomic variant analysis and reporting
CN103397103B (zh) * 2013-08-26 2016-04-20 中国人民解放军第三军医大学第三附属医院 一种检测socs家族基因标签单核甘酸多态性位点的方法及试剂盒
SI3063275T1 (sl) 2013-10-31 2020-02-28 Resolve Therapeutics, Llc Terapevtske fuzije nukleaza-albumin in postopki
EP2886140A1 (en) 2013-12-17 2015-06-24 University of Limerick An apparatus for the extracorporeal treatment of blood
US20170269075A1 (en) * 2014-05-12 2017-09-21 Biogen Ma Inc. Biomarkers predictive of lupus progression and uses thereof
MA45554A (fr) 2016-07-01 2019-05-08 Resolve Therapeutics Llc Fusions de binucléase optimisées.
CN111315767B (zh) 2017-08-22 2025-03-18 萨纳生物有限责任公司 可溶性干扰素受体及其用途
JP2024536558A (ja) * 2021-10-18 2024-10-04 カーステン マニュファクチュアリング コーポレーション ゴルフクラブセンサハウジング

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7022476B2 (en) * 2002-02-26 2006-04-04 New York Society For Ruptured And Crippled Maintaining The Hospital For Special Surgery Human FcγRIIB gene polymorphisms for assessing development of systemic lupus erythematosus and compositions for use thereof
US20070269827A1 (en) * 2006-05-18 2007-11-22 Oklahoma Medical Research Foundation Predicting and Diagnosing Patients With Autoimmune Disease
CN103298950B (zh) * 2007-05-21 2015-01-21 健泰科生物技术公司 用于鉴定和治疗狼疮的方法和组合物
JP2012519009A (ja) * 2009-03-03 2012-08-23 メルク セローノ ソシエテ アノニム Bank1関連snp及びsle並びに/又はms感受性

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Publication number Publication date
AU2009296393A1 (en) 2010-04-01
BRPI0913778A2 (pt) 2015-10-20
CN102224258A (zh) 2011-10-19
IL211462A0 (en) 2011-05-31
EP2344674A2 (en) 2011-07-20
KR20110081161A (ko) 2011-07-13
CA2736373A1 (en) 2010-04-01
WO2010036960A2 (en) 2010-04-01
WO2010036960A3 (en) 2010-09-30
WO2010036960A8 (en) 2011-04-28
EP2344674A4 (en) 2012-11-07
MX2011003273A (es) 2011-04-28
US20100099101A1 (en) 2010-04-22

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