CN102224258A - 用于治疗、诊断和监测狼疮的方法 - Google Patents

用于治疗、诊断和监测狼疮的方法 Download PDF

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Publication number
CN102224258A
CN102224258A CN200980146949XA CN200980146949A CN102224258A CN 102224258 A CN102224258 A CN 102224258A CN 200980146949X A CN200980146949X A CN 200980146949XA CN 200980146949 A CN200980146949 A CN 200980146949A CN 102224258 A CN102224258 A CN 102224258A
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locus
variation
lupus
experimenter
snp
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CN200980146949XA
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Chinese (zh)
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T·W·伯伦斯
R·R·格拉姆
G·霍姆
W·A·奥特曼
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F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN200980146949XA 2008-09-26 2009-09-25 用于治疗、诊断和监测狼疮的方法 Pending CN102224258A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10065908P 2008-09-26 2008-09-26
US61/100,659 2008-09-26
PCT/US2009/058478 WO2010036960A2 (en) 2008-09-26 2009-09-25 Methods for treating, diagnosing, and monitoring lupus

Publications (1)

Publication Number Publication Date
CN102224258A true CN102224258A (zh) 2011-10-19

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CN200980146949XA Pending CN102224258A (zh) 2008-09-26 2009-09-25 用于治疗、诊断和监测狼疮的方法

Country Status (11)

Country Link
US (1) US20100099101A1 (enExample)
EP (1) EP2344674A4 (enExample)
JP (1) JP2012503985A (enExample)
KR (1) KR20110081161A (enExample)
CN (1) CN102224258A (enExample)
AU (1) AU2009296393A1 (enExample)
BR (1) BRPI0913778A2 (enExample)
CA (1) CA2736373A1 (enExample)
IL (1) IL211462A0 (enExample)
MX (1) MX2011003273A (enExample)
WO (1) WO2010036960A2 (enExample)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102360016A (zh) * 2011-07-21 2012-02-22 南京工业大学 流式微球法对SLE的Sm-RNP抗体检测试剂盒的制备
CN104736556A (zh) * 2012-10-08 2015-06-24 弗·哈夫曼-拉罗切有限公司 结合irf5的细胞穿透肽
CN105229649A (zh) * 2013-03-15 2016-01-06 百世嘉（上海）医疗技术有限公司 用于疾病关联的人类基因组变异分析和报告的系统及方法
CN108753946A (zh) * 2007-05-21 2018-11-06 健泰科生物技术公司 用于鉴定和治疗狼疮的方法和组合物
CN111965358A (zh) * 2013-02-08 2020-11-20 阿勒格尼-辛格研究所 细胞结合的补体激活产物作为狼疮前期诊断性生物标志物

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112012007778A2 (pt) * 2009-10-07 2020-08-11 Genentech, Inc. método para identificar lúpus, método para avaliar se um sujeito está em risco de desenvolver lúpus, medicamentos para tratar uma condição de lupus, método e usos de um agente terapêutico.
LT2496691T (lt) 2009-11-02 2017-06-12 University Of Washington Terapinės nukleazės kompozicijos ir būdai
CN102465170A (zh) * 2010-11-05 2012-05-23 复旦大学附属华山医院 一种检测bank1基因单核苷酸多态性的方法
CA2827102A1 (en) * 2011-02-10 2012-08-16 Genqual Corporation Methods of prognosing and administering treatment for inflammatory disorders
HRP20180564T1 (hr) 2011-04-29 2018-06-01 University of Washington, UW Center for Commercialization Terapijski pripravci nukleaze i postupci
WO2014058254A1 (ko) * 2012-10-10 2014-04-17 가톨릭대학교 산학협력단 １ｑ２５．１(RABGAP1L) 위치, 6P21.32 (C4) 위치 및 １０ｑ２１．３위치의 ＤＮＡ 복제 수 변이 검출용 프라이머를 포함하는 전신성 홍반성 루푸스 발병 위험도 예측용 조성물
KR101491214B1 (ko) * 2012-10-10 2015-02-06 가톨릭대학교 산학협력단 １ｑ２５．１(RABGAP1L) 위치, 6p21.32 (C4) 위치 및 １０ｑ２１．３위치의 ＤＮＡ 복제 수 변이 검출용 프라이머를 포함하는 전신성 홍반성 루푸스 발병 위험도 예측용 조성물
CN103397103B (zh) * 2013-08-26 2016-04-20 中国人民解放军第三军医大学第三附属医院 一种检测socs家族基因标签单核甘酸多态性位点的方法及试剂盒
EP3063275B1 (en) 2013-10-31 2019-09-25 Resolve Therapeutics, LLC Therapeutic nuclease-albumin fusions and methods
EP2886140A1 (en) 2013-12-17 2015-06-24 University of Limerick An apparatus for the extracorporeal treatment of blood
US20170269075A1 (en) * 2014-05-12 2017-09-21 Biogen Ma Inc. Biomarkers predictive of lupus progression and uses thereof
DK3478830T3 (da) 2016-07-01 2024-05-21 Resolve Therapeutics Llc Optimerede binucleasefusioner og metoder
MX2020002070A (es) 2017-08-22 2020-03-24 Sanabio Llc Receptores solubles de interferon y usos de los mismos.
US20230123898A1 (en) * 2021-10-18 2023-04-20 Karsten Manufacturing Corporation Golf club sensor housing

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7022476B2 (en) * 2002-02-26 2006-04-04 New York Society For Ruptured And Crippled Maintaining The Hospital For Special Surgery Human FcγRIIB gene polymorphisms for assessing development of systemic lupus erythematosus and compositions for use thereof
US20070269827A1 (en) * 2006-05-18 2007-11-22 Oklahoma Medical Research Foundation Predicting and Diagnosing Patients With Autoimmune Disease
CN108753946A (zh) * 2007-05-21 2018-11-06 健泰科生物技术公司 用于鉴定和治疗狼疮的方法和组合物
CA2749869A1 (en) * 2009-03-03 2010-09-10 Merck Serono S.A. Bank1 related snps and sle and/or ms susceptibility

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108753946A (zh) * 2007-05-21 2018-11-06 健泰科生物技术公司 用于鉴定和治疗狼疮的方法和组合物
CN102360016A (zh) * 2011-07-21 2012-02-22 南京工业大学 流式微球法对SLE的Sm-RNP抗体检测试剂盒的制备
CN104736556A (zh) * 2012-10-08 2015-06-24 弗·哈夫曼-拉罗切有限公司 结合irf5的细胞穿透肽
CN111965358A (zh) * 2013-02-08 2020-11-20 阿勒格尼-辛格研究所 细胞结合的补体激活产物作为狼疮前期诊断性生物标志物
CN105229649A (zh) * 2013-03-15 2016-01-06 百世嘉（上海）医疗技术有限公司 用于疾病关联的人类基因组变异分析和报告的系统及方法

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Publication number Publication date
CA2736373A1 (en) 2010-04-01
BRPI0913778A2 (pt) 2015-10-20
WO2010036960A2 (en) 2010-04-01
WO2010036960A8 (en) 2011-04-28
IL211462A0 (en) 2011-05-31
US20100099101A1 (en) 2010-04-22
JP2012503985A (ja) 2012-02-16
AU2009296393A1 (en) 2010-04-01
EP2344674A2 (en) 2011-07-20
EP2344674A4 (en) 2012-11-07
MX2011003273A (es) 2011-04-28
WO2010036960A3 (en) 2010-09-30
KR20110081161A (ko) 2011-07-13

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Application publication date: 20111019