KR20110021691A - 메트포르민 메탄설폰산염, 그의 제조방법, 그를 포함하는 약학 조성물 및 그를 포함하는 복합제제 - Google Patents

메트포르민 메탄설폰산염, 그의 제조방법, 그를 포함하는 약학 조성물 및 그를 포함하는 복합제제 Download PDF

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KR20110021691A
KR20110021691A KR1020100082553A KR20100082553A KR20110021691A KR 20110021691 A KR20110021691 A KR 20110021691A KR 1020100082553 A KR1020100082553 A KR 1020100082553A KR 20100082553 A KR20100082553 A KR 20100082553A KR 20110021691 A KR20110021691 A KR 20110021691A
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South Korea
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metformin
cancer
methanesulfonate
diabetes
composition
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KR1020100082553A
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English (en)
Korean (ko)
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김성욱
전성수
민창희
구자성
강민석
김용은
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한올바이오파마주식회사
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Publication of KR20110021691A publication Critical patent/KR20110021691A/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C309/04—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing only one sulfo group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/145—Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/24—Y being a hetero atom
    • C07C279/26—X and Y being nitrogen atoms, i.e. biguanides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
KR1020100082553A 2009-08-25 2010-08-25 메트포르민 메탄설폰산염, 그의 제조방법, 그를 포함하는 약학 조성물 및 그를 포함하는 복합제제 KR20110021691A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020090078549 2009-08-25
KR20090078549 2009-08-25

Related Child Applications (1)

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KR1020120059607A Division KR20120065308A (ko) 2009-08-25 2012-06-04 메트포르민 메탄설폰산염, 그의 제조방법, 그를 포함하는 약학 조성물 및 그를 포함하는 복합제제

Publications (1)

Publication Number Publication Date
KR20110021691A true KR20110021691A (ko) 2011-03-04

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KR1020100082553A KR20110021691A (ko) 2009-08-25 2010-08-25 메트포르민 메탄설폰산염, 그의 제조방법, 그를 포함하는 약학 조성물 및 그를 포함하는 복합제제
KR1020120059607A KR20120065308A (ko) 2009-08-25 2012-06-04 메트포르민 메탄설폰산염, 그의 제조방법, 그를 포함하는 약학 조성물 및 그를 포함하는 복합제제

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KR1020120059607A KR20120065308A (ko) 2009-08-25 2012-06-04 메트포르민 메탄설폰산염, 그의 제조방법, 그를 포함하는 약학 조성물 및 그를 포함하는 복합제제

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KR (2) KR20110021691A (fr)
WO (1) WO2011025267A2 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014182028A1 (fr) * 2013-05-07 2014-11-13 재단법인 통합의료진흥원 Composition pour le traitement du diabète, contenant un extrait d'yukmijihwangtang
WO2017063155A1 (fr) * 2015-10-14 2017-04-20 吉林海格力斯医药生物科技发展有限公司 Composé pour le traitement d'une lésion de la moelle osseuse provoquée par la radiothérapie ou la chimiothérapie

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102886045A (zh) 2005-02-03 2013-01-23 综合医院公司 治疗吉非替尼耐药性癌症的方法
AR057854A1 (es) 2005-11-04 2007-12-19 Wyeth Corp Combinaciones antineoplasicas con inhibidor de mtor, herceptina y/o hki-272 (e)-n-{4-[3-cloro-4-(2-piridinilmetoxi) anilino]-3-ciano-7-etoxi-6-quinolinil}-4-(dimetilamino)-2-butenamida
US8022216B2 (en) 2007-10-17 2011-09-20 Wyeth Llc Maleate salts of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof
EP2915532B1 (fr) 2008-06-17 2016-10-19 Wyeth LLC Combinaisons antinéoplasiques contenant du HKI-272 et de la vinorelbine
JP5681108B2 (ja) 2008-08-04 2015-03-04 ワイス・エルエルシー ４−アニリノ−３−シアノキノリンとカペシタビンの抗新生物薬の組合せ
RU2011139363A (ru) 2009-04-06 2013-05-20 ВАЙЕТ ЭлЭлСи Схема лечения рака молочной железы с использованием нератиниба
CA2780332C (fr) 2009-11-09 2018-01-30 Wyeth Llc Spheroides de medicament enrobes et utilisations de ceux-ci pour eliminer ou reduire des affections telles que le vomissement et la diarrhee
KR101432892B1 (ko) * 2012-09-17 2014-08-21 가톨릭대학교 산학협력단 메트포민을 이용한 루프스를 포함하는 면역질환의 예방 또는 치료용 조성물
CN105330575A (zh) * 2015-10-14 2016-02-17 吉林海格力斯医药生物科技发展有限公司 一种用于治疗放疗、化疗引起的骨髓损伤的化合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1591114A1 (fr) * 2004-03-12 2005-11-02 Fournier Laboratories Ireland Limited Utilisation de la metformine et de l'Orlistat pour le traitement ou la prévention de l'obésité
KR100774774B1 (ko) * 2006-07-20 2007-11-07 일동제약주식회사 메트포르민 서방성 제제 및 그 제조방법
AR065669A1 (es) * 2007-03-09 2009-06-24 Indigene Pharmaceuticals Inc Combinacion de metformina r-(+) lipoato y agentes antihipertensivos para el tratamiento de hiperglucemia diabetica y las complicaciones diabeticas

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014182028A1 (fr) * 2013-05-07 2014-11-13 재단법인 통합의료진흥원 Composition pour le traitement du diabète, contenant un extrait d'yukmijihwangtang
US10765647B2 (en) 2013-05-07 2020-09-08 Comprehensive And Integrative Medicine Institute Composition for treating diabetes, containing extract of yukmijihwangtang
WO2017063155A1 (fr) * 2015-10-14 2017-04-20 吉林海格力斯医药生物科技发展有限公司 Composé pour le traitement d'une lésion de la moelle osseuse provoquée par la radiothérapie ou la chimiothérapie

Also Published As

Publication number Publication date
WO2011025267A3 (fr) 2011-07-21
WO2011025267A2 (fr) 2011-03-03
KR20120065308A (ko) 2012-06-20

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