KR20110020903A - 키메라 나트륨이뇨성 폴리펩티드 및 심장 리모델링 억제 방법 - Google Patents
키메라 나트륨이뇨성 폴리펩티드 및 심장 리모델링 억제 방법 Download PDFInfo
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- A61K38/22—Hormones
- A61K38/2242—Atrial natriuretic factor complex: Atriopeptins, atrial natriuretic protein [ANP]; Cardionatrin, Cardiodilatin
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- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
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| WO2010078325A2 (en) | 2008-12-29 | 2010-07-08 | Mayo Foundation For Medical Education And Research | Natriuretic polypeptides for reducing or preventing restenosis |
| WO2011005939A2 (en) | 2009-07-09 | 2011-01-13 | Mayo Foundation For Medical Education And Research | Long acting atrial natriuretic peptide (la-anp) and methods for use thereof |
| CA2823066A1 (en) | 2010-12-27 | 2012-07-05 | Alexion Pharma International Sarl | Compositions comprising natriuretic peptides and methods of use thereof |
| WO2012115772A2 (en) * | 2011-02-25 | 2012-08-30 | Medtronic, Inc. | Therapy for kidney disease and/or heart failure |
| US20120220528A1 (en) * | 2011-02-25 | 2012-08-30 | Medtronic, Inc. | Systems and methods for therapy of kidney disease and/or heart failure using chimeric natriuretic peptides |
| CN103906761B (zh) | 2011-08-30 | 2016-12-21 | 梅约医学教育与研究基金会 | 利钠多肽 |
| EP2750697A4 (en) * | 2011-09-02 | 2015-03-25 | Medtronic Inc | CHIMERIC NATRIURETIC PEPTIDE COMPOSITIONS AND METHOD FOR THE PRODUCTION THEREOF |
| US9611305B2 (en) | 2012-01-06 | 2017-04-04 | Mayo Foundation For Medical Education And Research | Treating cardiovascular or renal diseases |
| US10052366B2 (en) | 2012-05-21 | 2018-08-21 | Alexion Pharmaceuticsl, Inc. | Compositions comprising alkaline phosphatase and/or natriuretic peptide and methods of use thereof |
| US10822596B2 (en) | 2014-07-11 | 2020-11-03 | Alexion Pharmaceuticals, Inc. | Compositions and methods for treating craniosynostosis |
| CA2967851C (en) | 2014-12-05 | 2024-02-27 | Alexion Pharmaceuticals, Inc. | Treating seizure with recombinant alkaline phosphatase |
| US10603361B2 (en) | 2015-01-28 | 2020-03-31 | Alexion Pharmaceuticals, Inc. | Methods of treating a subject with an alkaline phosphatase deficiency |
| RU2745528C2 (ru) | 2015-08-17 | 2021-03-26 | Алексион Фармасьютикалз, Инк. | Производство щелочных фосфатаз |
| WO2017058822A1 (en) | 2015-09-28 | 2017-04-06 | Alexion Pharmaceuticals, Inc. | Identifying effective dosage regimens for tissue non-specific alkaline phosphatase (tnsalp)-enzyme replacement therapy of hypophosphatasia |
| WO2017074466A1 (en) | 2015-10-30 | 2017-05-04 | Alexion Pharmaceuticals, Inc. | Methods for treating craniosynostosis in a patient |
| EP3426286A4 (en) | 2016-03-08 | 2019-12-04 | Alexion Pharmaceuticals, Inc. | PROCESS FOR TREATING HYPOPHOSPHATASIA IN CHILDREN |
| EP3436020A4 (en) | 2016-04-01 | 2019-12-25 | Alexion Pharmaceuticals, Inc. | METHOD FOR TREATING HYPOPHOSPHATASIE IN TEENS AND ADULTS |
| JP7613826B2 (ja) | 2016-04-01 | 2025-01-15 | アレクシオン ファーマシューティカルズ， インコーポレイテッド | アルカリホスファターゼによって筋力低下を治療すること |
| US10988744B2 (en) | 2016-06-06 | 2021-04-27 | Alexion Pharmaceuticals, Inc. | Method of producing alkaline phosphatase |
| EP3500289B1 (en) | 2016-08-18 | 2024-10-09 | Alexion Pharmaceuticals, Inc. | Asfotase alfa for use in treating tracheobronchomalacia |
| SG10202101479PA (en) * | 2016-08-18 | 2021-03-30 | Nat Univ Singapore | Peptides with vasodilatory and/or diuretic functions |
| CA3057502A1 (en) | 2017-03-31 | 2018-10-04 | Alexion Pharmaceuticals, Inc. | Methods for treating hypophosphatasia (hpp) in adults and adolescents |
| JP2021519590A (ja) | 2018-03-30 | 2021-08-12 | アレクシオン ファーマシューティカルズ， インコーポレイテッド | 糖タンパク質の製造 |
| JP2021534111A (ja) | 2018-08-10 | 2021-12-09 | アレクシオン ファーマシューティカルズ， インコーポレイテッド | アルカリホスファターゼを用いて神経線維腫症１型および関連状態を治療する方法 |
| US12433938B2 (en) | 2019-12-09 | 2025-10-07 | Alexion Pharmaceuticals, Inc. | Alkaline phosphatase polypeptides and methods of use thereof |
| WO2021183928A1 (en) * | 2020-03-13 | 2021-09-16 | Mayo Foundation For Medical Education And Research | Assessing and treating acute decompensated heart failure |
| AU2022218782A1 (en) | 2021-02-12 | 2023-08-17 | Alexion Pharmaceuticals, Inc. | Alkaline phosphatase polypeptides and methods of use thereof |
| AR130935A1 (es) | 2022-11-02 | 2025-02-05 | Novo Nordisk As | Compuestos de cnp |
| WO2025054172A1 (en) | 2023-09-05 | 2025-03-13 | E-Star Biotech, LLC | Formulations of manp and uses thereof |
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| US4161521A (en) * | 1975-08-08 | 1979-07-17 | Merck & Co., Inc. | Somatostatin analogs |
| US4757048A (en) * | 1985-11-05 | 1988-07-12 | Biotechnology Research Associates J.V. | Synthetic analogs of atrial natriuretic peptides |
| US4935492A (en) * | 1987-12-24 | 1990-06-19 | California Biotechnology Inc. | Cyclic analogs of atrial natriuretic peptides |
| AU5043900A (en) * | 1999-05-24 | 2000-12-12 | Mayo Foundation For Medical Education And Research | Adenovirus vectors encoding brain natriuretic peptide |
| US6407211B1 (en) * | 1999-12-17 | 2002-06-18 | Mayo Foundation For Medical Education And Research | Chimeric natriuretic peptides |
| US20060019890A1 (en) * | 2004-01-15 | 2006-01-26 | Kapoun Ann M | Method for treating cardiac remodeling following myocardial injury |
| US20070042957A1 (en) * | 2005-08-19 | 2007-02-22 | Mayo Foundation For Medical Education And Research | Type v phosphodiesterase inhibitors and natriuretic polypeptides |
| US7803901B2 (en) * | 2005-09-16 | 2010-09-28 | Mayo Foundation For Medical Education And Research | Polypeptides with natriuresis activity |
| TW200817431A (en) * | 2006-08-08 | 2008-04-16 | Mayo Foundation | Diuretic and natriuretic polypeptides |
| BRPI0716228A2 (pt) * | 2006-09-08 | 2013-10-15 | Mayo Foundation | Polipeptídeos aquaréticos e natriuréticos carecendo de atividade vasodilatadora |
| PT2765139T (pt) * | 2007-07-20 | 2017-07-14 | Mayo Foundation | Polipéptidos natriuréticos |
| DK2307447T3 (da) * | 2008-07-02 | 2016-06-20 | Mayo Foundation | Natriuretiske polypeptider med unikke farmakologiske profiler |
| WO2010048308A2 (en) * | 2008-10-24 | 2010-04-29 | Deborah Dickey | Natriuretic polypeptides |
| WO2010078325A2 (en) * | 2008-12-29 | 2010-07-08 | Mayo Foundation For Medical Education And Research | Natriuretic polypeptides for reducing or preventing restenosis |
| US20120053123A1 (en) * | 2009-05-05 | 2012-03-01 | Mayo Foundation For Medical Education And Research | Natriuretic polypeptides having mutations within their disulfide rings |
| WO2011005939A2 (en) * | 2009-07-09 | 2011-01-13 | Mayo Foundation For Medical Education And Research | Long acting atrial natriuretic peptide (la-anp) and methods for use thereof |
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- 2009-06-03 CA CA2727085A patent/CA2727085A1/en not_active Abandoned
- 2009-06-03 EP EP09759320A patent/EP2303305A4/en not_active Withdrawn
- 2009-06-03 US US12/996,500 patent/US20110152194A1/en not_active Abandoned
- 2009-06-03 WO PCT/US2009/046095 patent/WO2009149161A2/en not_active Ceased
- 2009-06-03 KR KR1020117000303A patent/KR20110020903A/ko not_active Withdrawn
- 2009-06-03 JP JP2011512608A patent/JP2011522824A/ja active Pending
- 2009-06-03 AU AU2009256222A patent/AU2009256222A1/en not_active Abandoned
- 2009-06-03 CN CN2009801289321A patent/CN102143757A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2727085A1 (en) | 2009-12-10 |
| CN102143757A (zh) | 2011-08-03 |
| WO2009149161A9 (en) | 2010-04-08 |
| JP2011522824A (ja) | 2011-08-04 |
| AU2009256222A1 (en) | 2009-12-10 |
| EP2303305A2 (en) | 2011-04-06 |
| WO2009149161A2 (en) | 2009-12-10 |
| US20110152194A1 (en) | 2011-06-23 |
| EP2303305A4 (en) | 2012-07-04 |
| WO2009149161A3 (en) | 2010-06-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
Patent event date: 20110106 Patent event code: PA01051R01D Comment text: International Patent Application |
|
| PG1501 | Laying open of application | ||
| PC1203 | Withdrawal of no request for examination | ||
| WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |