KR20100101574A - 클라불란산의 제약 제제 - Google Patents
클라불란산의 제약 제제 Download PDFInfo
- Publication number
- KR20100101574A KR20100101574A KR1020107011374A KR20107011374A KR20100101574A KR 20100101574 A KR20100101574 A KR 20100101574A KR 1020107011374 A KR1020107011374 A KR 1020107011374A KR 20107011374 A KR20107011374 A KR 20107011374A KR 20100101574 A KR20100101574 A KR 20100101574A
- Authority
- KR
- South Korea
- Prior art keywords
- clavulanate
- pharmaceutical composition
- clavulanic acid
- mixture
- potassium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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- HZZVJAQRINQKSD-UHFFFAOYSA-N Clavulanic acid Natural products OC(=O)C1C(=CCO)OC2CC(=O)N21 HZZVJAQRINQKSD-UHFFFAOYSA-N 0.000 title claims description 151
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- ABVRVIZBZKUTMK-JSYANWSFSA-M potassium clavulanate Chemical compound [K+].[O-]C(=O)[C@H]1C(=C/CO)/O[C@@H]2CC(=O)N21 ABVRVIZBZKUTMK-JSYANWSFSA-M 0.000 claims abstract description 64
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Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/424—Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
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| US99607907P | 2007-10-26 | 2007-10-26 | |
| US60/996,079 | 2007-10-26 |
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| KR20100101574A true KR20100101574A (ko) | 2010-09-17 |
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| KR1020107011374A Withdrawn KR20100101574A (ko) | 2007-10-26 | 2008-10-24 | 클라불란산의 제약 제제 |
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| US (1) | US20090270358A1 (https=) |
| EP (1) | EP2214680A4 (https=) |
| JP (1) | JP2011500811A (https=) |
| KR (1) | KR20100101574A (https=) |
| CN (1) | CN101918004A (https=) |
| AU (1) | AU2008317315A1 (https=) |
| BR (1) | BRPI0818702A2 (https=) |
| CA (1) | CA2703224A1 (https=) |
| IL (1) | IL205313A0 (https=) |
| MX (1) | MX2010004556A (https=) |
| WO (1) | WO2009055038A1 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102011052288A1 (de) | 2010-10-18 | 2012-04-19 | Hyundai Motor Co. | Einrichtung und Verfahren zum Steuern eines Niederdruck-Abgasrückführungs(EGR)-Systems |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7635773B2 (en) | 2008-04-28 | 2009-12-22 | Cydex Pharmaceuticals, Inc. | Sulfoalkyl ether cyclodextrin compositions |
| BRPI1013901A2 (pt) * | 2009-04-29 | 2019-09-24 | Rexahn Pharmaceuticals Inc | formulação de clavulanato para neuroproteção e tratamento de distúrbios neurodegenerativos |
| CN102058584B (zh) * | 2010-12-30 | 2012-01-25 | 石药集团河北中润制药有限公司 | 克拉维酸钾/微晶纤维素组合物的制备方法 |
| DK3702374T3 (da) | 2012-02-15 | 2022-06-27 | Cydex Pharmaceuticals Inc | Fremsgangsmåde til fremstilling for cyclodextrin-derivater |
| WO2014066274A1 (en) | 2012-10-22 | 2014-05-01 | Cydex Pharmaceuticals, Inc. | Alkylated cyclodextrin compositions and processes for preparing and using the same |
| ES2821528T3 (es) | 2012-11-14 | 2021-04-26 | Grace W R & Co | Composiciones que contienen un material biológicamente activo y un óxido inorgánico no ordenado |
| EP3125873B1 (en) | 2014-04-04 | 2020-06-03 | Pharmaquest International Center, LLC | Disintegrating monolithic modified release tablets containing quadri-layer extended release granules |
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| JO984B1 (en) * | 1977-10-11 | 1979-12-01 | بيتشام غروب ليمتد | A dry pharmaceutical compound with a suitable dosage unit for oral administration |
| NZ189022A (en) * | 1977-12-08 | 1981-11-19 | Beecham Group Ltd | Pharmaceutically acceptable particles of clavulanates dispersed in a polymeric binder |
| NZ198241A (en) * | 1980-09-27 | 1983-12-16 | Beecham Group Ltd | Tablet containing amoxycillin and potassium clavulanate |
| GB9109862D0 (en) | 1991-05-08 | 1991-07-03 | Beecham Lab Sa | Pharmaceutical formulations |
| GB9405856D0 (en) * | 1994-03-24 | 1994-05-11 | Smithkline Beecham Plc | Pharmaceutical formulation |
| GB9518917D0 (en) * | 1995-09-15 | 1995-11-15 | Smithkline Beecham Plc | Compounds |
| IE990159A1 (en) * | 1999-02-26 | 2000-09-20 | Fuisz Internat Ltd | Storage Stable Amoxycillin and Clavulanate Suspension Composition. |
| US6426342B2 (en) | 1999-08-16 | 2002-07-30 | Revaax Pharmaceuticals, Llc | Use of β-lactamase inhibitors as neuroprotectants |
| US6489319B2 (en) * | 1999-08-16 | 2002-12-03 | Revaax Pharmaceuticals, Llc | Neurotherapeutic use of carboxypeptidase inhibitors |
| ES2258980T3 (es) | 1999-08-16 | 2006-09-16 | Revaax Pharmaceuticals Llc | Composiciones farmaceuticas que comprenden acido clavulanico o derivados del mismo para el tratamiento de trastornos del comportamiento. |
| US7166626B2 (en) | 2001-06-18 | 2007-01-23 | Revaax Pharmaceuticals, Llc | Therapeutic treatment for sexual dysfunction |
| IL154370A0 (en) * | 2003-02-10 | 2003-09-17 | Chemagis Ltd | Solid amorphous mixtures, processes for the preparation thereof and pharmaceutical compositions containing the same |
| SI21402A (sl) * | 2003-02-12 | 2004-08-31 | LEK farmacevtska dru�ba d.d. | Obloženi delci in farmacevtske oblike |
| KR101289115B1 (ko) * | 2004-08-13 | 2013-07-23 | 엠에스디 인터내셔널 홀딩즈 게엠베하 | 항생제인 트리아졸 및 코르티코스테로이드를 포함하는약제학적 제형 |
| DE102006007830A1 (de) * | 2006-02-17 | 2007-08-30 | Grünenthal GmbH | Lagerstabile orale Darreichungsform von Amoxicillin und Clavulansäure |
| CA2644911A1 (en) * | 2006-03-24 | 2007-10-04 | Panacea Biotec Ltd. | Antibiotic compositions of modified release and process of production thereof |
| BRPI1013901A2 (pt) * | 2009-04-29 | 2019-09-24 | Rexahn Pharmaceuticals Inc | formulação de clavulanato para neuroproteção e tratamento de distúrbios neurodegenerativos |
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- 2008-10-24 CA CA2703224A patent/CA2703224A1/en not_active Abandoned
- 2008-10-24 EP EP20080842941 patent/EP2214680A4/en not_active Withdrawn
- 2008-10-24 MX MX2010004556A patent/MX2010004556A/es not_active Application Discontinuation
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- 2008-10-24 WO PCT/US2008/012126 patent/WO2009055038A1/en not_active Ceased
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102011052288A1 (de) | 2010-10-18 | 2012-04-19 | Hyundai Motor Co. | Einrichtung und Verfahren zum Steuern eines Niederdruck-Abgasrückführungs(EGR)-Systems |
Also Published As
| Publication number | Publication date |
|---|---|
| US20090270358A1 (en) | 2009-10-29 |
| EP2214680A4 (en) | 2010-12-29 |
| EP2214680A1 (en) | 2010-08-11 |
| WO2009055038A1 (en) | 2009-04-30 |
| CA2703224A1 (en) | 2009-04-30 |
| AU2008317315A1 (en) | 2009-04-30 |
| IL205313A0 (en) | 2010-12-30 |
| BRPI0818702A2 (pt) | 2015-04-22 |
| MX2010004556A (es) | 2010-07-01 |
| CN101918004A (zh) | 2010-12-15 |
| JP2011500811A (ja) | 2011-01-06 |
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