KR20100037031A - 유전자 녹아웃 중온성 및 호열성 생물체, 및 이의 사용 방법 - Google Patents
유전자 녹아웃 중온성 및 호열성 생물체, 및 이의 사용 방법 Download PDFInfo
- Publication number
- KR20100037031A KR20100037031A KR1020097025740A KR20097025740A KR20100037031A KR 20100037031 A KR20100037031 A KR 20100037031A KR 1020097025740 A KR1020097025740 A KR 1020097025740A KR 20097025740 A KR20097025740 A KR 20097025740A KR 20100037031 A KR20100037031 A KR 20100037031A
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- South Korea
- Prior art keywords
- genetically modified
- microorganism
- thermophilic
- mesophilic
- gene
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/06—Ethanol, i.e. non-beverage
- C12P7/08—Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate
- C12P7/10—Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate substrate containing cellulosic material
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1217—Phosphotransferases with a carboxyl group as acceptor (2.7.2)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
- C12N9/92—Glucose isomerase (5.3.1.5; 5.3.1.9; 5.3.1.18)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/06—Ethanol, i.e. non-beverage
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/06—Ethanol, i.e. non-beverage
- C12P7/065—Ethanol, i.e. non-beverage with microorganisms other than yeasts
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01002—Alcohol dehydrogenase (NADP+) (1.1.1.2), i.e. aldehyde reductase
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01027—L-Lactate dehydrogenase (1.1.1.27)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/02—Oxidoreductases acting on the CH-OH group of donors (1.1) with a cytochrome as acceptor (1.1.2)
- C12Y101/02003—L-Lactate dehydrogenase (cytochrome) (1.1.2.3)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y203/00—Acyltransferases (2.3)
- C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
- C12Y203/01008—Phosphate acetyltransferase (2.3.1.8)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/01—Phosphotransferases with an alcohol group as acceptor (2.7.1)
- C12Y207/01017—Xylulokinase (2.7.1.17)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/02—Phosphotransferases with a carboxy group as acceptor (2.7.2)
- C12Y207/02001—Acetate kinase (2.7.2.1)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y503/00—Intramolecular oxidoreductases (5.3)
- C12Y503/01—Intramolecular oxidoreductases (5.3) interconverting aldoses and ketoses (5.3.1)
- C12Y503/01005—Xylose isomerase (5.3.1.5)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P2203/00—Fermentation products obtained from optionally pretreated or hydrolyzed cellulosic or lignocellulosic material as the carbon source
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US91697807P | 2007-05-09 | 2007-05-09 | |
| US60/916,978 | 2007-05-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20100037031A true KR20100037031A (ko) | 2010-04-08 |
Family
ID=40002867
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020097025740A Ceased KR20100037031A (ko) | 2007-05-09 | 2008-05-09 | 유전자 녹아웃 중온성 및 호열성 생물체, 및 이의 사용 방법 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US8435770B2 (enExample) |
| EP (5) | EP2511285A3 (enExample) |
| JP (1) | JP2010526536A (enExample) |
| KR (1) | KR20100037031A (enExample) |
| CN (1) | CN101848924A (enExample) |
| AU (1) | AU2008251465B2 (enExample) |
| BR (1) | BRPI0811556A2 (enExample) |
| CA (1) | CA2685879A1 (enExample) |
| IL (1) | IL201824A0 (enExample) |
| NZ (2) | NZ581493A (enExample) |
| RU (1) | RU2541785C2 (enExample) |
| WO (1) | WO2008141174A2 (enExample) |
| ZA (1) | ZA200908721B (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8163516B2 (en) * | 2008-02-08 | 2012-04-24 | Algenol Biofuels Inc. | Selection of ADH in genetically modified cyanobacteria for the production of ethanol |
| WO2009109630A1 (en) * | 2008-03-07 | 2009-09-11 | Dsm Ip Assets B.V. | A pentose sugar fermenting cell |
| DE102008031350B4 (de) * | 2008-07-02 | 2011-02-10 | Johann Wolfgang Goethe-Universität Frankfurt am Main | Prokaryotische Xylose-Isomerase zur Konstruktion Xylose-vergärender Hefen |
| WO2010014632A2 (en) | 2008-07-28 | 2010-02-04 | University Of Massachusetts | Methods and compositions for improving the production of products in microorganisms |
| US20120094343A1 (en) * | 2008-11-12 | 2012-04-19 | Mascoma Corporation | Gene Knockout Mesophilic and Thermophilic Organisms, and Methods of Use Thereof |
| EP2194120A1 (en) * | 2008-12-02 | 2010-06-09 | Total S.A. | Bioprocessing ligno-cellulose into ethanol with recombinant clostridium |
| US20120107892A1 (en) * | 2008-12-22 | 2012-05-03 | Frank Agbogbo | Production of ethanol from lignocellulosic biomass |
| WO2011059314A1 (en) * | 2009-11-12 | 2011-05-19 | Stichting Voor De Technische Wetenschappen | Pentose transporters and uses thereof |
| WO2011092638A2 (en) | 2010-01-26 | 2011-08-04 | Scale Biofuel Aps | Methods for producing and harvesting ethanol and apparatus for producing and harvesting the same |
| GB2478791A (en) * | 2010-03-19 | 2011-09-21 | Qteros Inc | Ethanol production by genetically-modified bacteria |
| US8927254B2 (en) | 2010-09-29 | 2015-01-06 | University Of Georgia Research Foundation, Inc. | Pyrococcus furiosus strains and methods of using same |
| CA2822654A1 (en) * | 2010-12-22 | 2012-06-28 | Mascoma Corporation | Genetically modified clostridium thermocellum engineered to ferment xylose |
| CA2864086C (en) | 2011-02-28 | 2018-07-10 | Midori Renewables, Inc. | Polymeric acid catalysts and uses thereof |
| US8962333B2 (en) | 2011-04-04 | 2015-02-24 | University Of Georgia Research Foundation, Inc. | Restriction/modification polypeptides, polynucleotides, and methods |
| EP2710308A1 (en) | 2011-05-18 | 2014-03-26 | Scale Biofuel APS | Solar-assisted volatile fermentation products production processes |
| WO2013041668A1 (en) * | 2011-09-22 | 2013-03-28 | Direvo Industrial Biotechnology Gmbh | Single-step bioconversion of lignocellulosic biomass to biofuels using extreme thermophilic bacteria |
| US9803221B2 (en) | 2011-09-30 | 2017-10-31 | Enchi Corporation | Engineering microorganisms to increase ethanol production by metabolic redirection |
| CA2857498A1 (en) * | 2011-11-30 | 2013-09-26 | Mascoma Corporation | Engineering an increase in ethanol production by altering cofactor specificity |
| US9309542B2 (en) | 2012-08-17 | 2016-04-12 | University Of Georgia Research Foundation, Inc. | Recombinant Caldicellulosiruptor bescii and methods of use |
| US9238845B2 (en) | 2012-08-24 | 2016-01-19 | Midori Usa, Inc. | Methods of producing sugars from biomass feedstocks |
| US9587256B2 (en) | 2012-09-06 | 2017-03-07 | University Of Georgia Research Foundation, Inc. | Sequestration of carbon dioxide with hydrogen to useful products |
| US9850512B2 (en) | 2013-03-15 | 2017-12-26 | The Research Foundation For The State University Of New York | Hydrolysis of cellulosic fines in primary clarified sludge of paper mills and the addition of a surfactant to increase the yield |
| US9951363B2 (en) | 2014-03-14 | 2018-04-24 | The Research Foundation for the State University of New York College of Environmental Science and Forestry | Enzymatic hydrolysis of old corrugated cardboard (OCC) fines from recycled linerboard mill waste rejects |
| GB2528177B (en) | 2014-06-11 | 2019-08-28 | Univ Duke | Compositions and methods for rapid and dynamic flux control using synthetic metabolic valves |
| CN104263680B (zh) * | 2014-09-05 | 2017-02-01 | 华南理工大学 | 一种嗜热厌氧杆菌及利用其生产乙醇的方法 |
| CN105154465A (zh) * | 2015-07-23 | 2015-12-16 | 昆明理工大学 | 一种敲除乙酸激酶基因的重组质粒及其应用 |
| CN106893745A (zh) * | 2017-04-12 | 2017-06-27 | 浙江畯和生物科技有限公司 | 一种木质纤维素生物质的高效转化利用方法 |
| TWI664286B (zh) * | 2017-08-02 | 2019-07-01 | 國立清華大學 | 生產醋酸的基因轉殖藍綠菌及其應用 |
| WO2019246488A1 (en) | 2018-06-21 | 2019-12-26 | Duke University | Compositions and methods for the production of pyruvic acid and related products using dynamic metabolic control |
| KR20220025884A (ko) | 2019-07-02 | 2022-03-03 | 코덱시스, 인코포레이티드 | 조작된 아세테이트 키나제 변이체 효소 |
| CN110484466B (zh) * | 2019-08-15 | 2023-04-21 | 华南理工大学 | 一种提高嗜热厌氧杆菌发酵性能的方法 |
| CN111423256A (zh) * | 2020-04-23 | 2020-07-17 | 上海国璨环境科技有限公司 | 一种有机垃圾热解方法 |
| CN117343885A (zh) * | 2022-07-04 | 2024-01-05 | 宁波牛形山生物科技合伙企业(有限合伙) | 一种通过代谢工程改造提高嗜热厌氧乙醇杆菌生物合成乳酸的方法 |
| WO2025240457A1 (en) * | 2024-05-13 | 2025-11-20 | North Carolina State University | Conversion of biomass into industrial chemicals using engineered bacteria |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6027895A (en) | 1995-09-12 | 2000-02-22 | The Ohio State University Research Foundation | Methods for cleaving DNA with nucleotide integrases |
| US5698421A (en) | 1995-09-12 | 1997-12-16 | The Ohio State Research Foundation | Ribonucleoprotein particles for cleaving double-stranded DNA and inserting an RNA/DNA molecule into the cleavage site |
| ES2231835T3 (es) * | 1996-09-27 | 2005-05-16 | Dsm Ip Assets B.V. | Genes biosinteticos ii de biotina. |
| US5804418A (en) | 1996-11-19 | 1998-09-08 | The Ohio State University Research Foundation | Methods for preparing nucleotide integrases |
| AU2973799A (en) | 1998-02-26 | 1999-09-15 | Ohio State Research Foundation, The | Methods for cleaving single-stranded and double-stranded dna substrates with nucleotide integrase |
| GB0000185D0 (en) | 2000-01-06 | 2000-03-01 | Agrol Limited | Ethanol production |
| GB0011186D0 (en) | 2000-05-09 | 2000-06-28 | Agrol Limited | Modification of bacteria |
| CN1336432A (zh) * | 2000-07-31 | 2002-02-20 | 武汉迪普生物技术有限公司 | 重组枯激酶的生产方法及其生物活性 |
| BR0114477A (pt) | 2000-10-06 | 2004-01-13 | Elsworth Biotech Ltd | Produção de etanol |
| US20030165859A1 (en) * | 2001-10-23 | 2003-09-04 | Invitrogen Corporation | Primers and methods for the detection and discrimination of nucleic acids |
| US7026464B2 (en) * | 2002-10-21 | 2006-04-11 | E. I. Du Pont De Nemours And Company | Natural promoters for gene expression in C1 metabolizing bacteria |
| EP1769092A4 (en) | 2004-06-29 | 2008-08-06 | Europ Nickel Plc | IMPROVED LIXIVIATION OF BASE METALS |
| US20060105348A1 (en) | 2004-11-15 | 2006-05-18 | Lee Jun E | Compositions and methods for the detection and discrimination of nucleic acids |
| WO2006099615A2 (en) | 2005-03-16 | 2006-09-21 | The Johns Hopkins University | Adenoviral fiber exchange shuttle system |
| KR20080012934A (ko) | 2005-05-04 | 2008-02-12 | 티엠오 리뉴어블스 리미티드 | 에탄올 생산을 위해 락테이트 디하이드로게나제 유전자가비활성화된 호열성 미생물 |
| GB0511602D0 (en) | 2005-06-07 | 2005-07-13 | Tmo Biotec Ltd | Microorganisms |
| ATE498358T1 (de) | 2005-06-29 | 2011-03-15 | Compumedics Ltd | Sensoranordnung mit leitfähiger brücke |
| US20090070896A1 (en) | 2005-08-30 | 2009-03-12 | Phyllom Llc | Insect resistant transgenic turf grass |
| GB0520344D0 (en) | 2005-10-06 | 2005-11-16 | Tmo Biotec Ltd | Microoganisms |
| CA2627191A1 (en) * | 2005-10-31 | 2007-05-10 | The Trustees Of Dartmouth College | Thermophilic organisms for conversion of lignocellulosic biomass to ethanol |
| TW200801513A (en) | 2006-06-29 | 2008-01-01 | Fermiscan Australia Pty Ltd | Improved process |
| ATE485370T1 (de) | 2006-09-14 | 2010-11-15 | Tmo Renewables Ltd | Lipase |
| EA017548B1 (ru) | 2006-09-28 | 2013-01-30 | Тмо Реньюаблз Лимитед | Термофильный микроорганизм, модифицированный для повышенной выработки этанола, и способ получения этанола при его использовании |
-
2008
- 2008-05-09 EP EP12164671A patent/EP2511285A3/en not_active Withdrawn
- 2008-05-09 WO PCT/US2008/063237 patent/WO2008141174A2/en not_active Ceased
- 2008-05-09 RU RU2009145274/10A patent/RU2541785C2/ru not_active IP Right Cessation
- 2008-05-09 EP EP08769395A patent/EP2064225A4/en not_active Withdrawn
- 2008-05-09 CN CN200880024031A patent/CN101848924A/zh active Pending
- 2008-05-09 KR KR1020097025740A patent/KR20100037031A/ko not_active Ceased
- 2008-05-09 BR BRPI0811556A patent/BRPI0811556A2/pt not_active IP Right Cessation
- 2008-05-09 AU AU2008251465A patent/AU2008251465B2/en not_active Ceased
- 2008-05-09 JP JP2010507693A patent/JP2010526536A/ja active Pending
- 2008-05-09 NZ NZ581493A patent/NZ581493A/en not_active IP Right Cessation
- 2008-05-09 US US12/599,458 patent/US8435770B2/en not_active Expired - Fee Related
- 2008-05-09 EP EP12164670A patent/EP2511284A3/en not_active Withdrawn
- 2008-05-09 EP EP12164672A patent/EP2511286A3/en not_active Withdrawn
- 2008-05-09 EP EP12164673A patent/EP2511287A3/en not_active Withdrawn
- 2008-05-09 CA CA002685879A patent/CA2685879A1/en not_active Abandoned
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2009
- 2009-10-29 IL IL201824A patent/IL201824A0/en unknown
- 2009-12-08 ZA ZA200908721A patent/ZA200908721B/xx unknown
-
2012
- 2012-04-20 NZ NZ599526A patent/NZ599526A/xx not_active IP Right Cessation
-
2013
- 2013-05-07 US US13/888,610 patent/US20150024450A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008141174A2 (en) | 2008-11-20 |
| CN101848924A (zh) | 2010-09-29 |
| AU2008251465B2 (en) | 2013-01-10 |
| IL201824A0 (en) | 2010-06-16 |
| NZ599526A (en) | 2013-07-26 |
| CA2685879A1 (en) | 2008-11-20 |
| EP2511286A2 (en) | 2012-10-17 |
| NZ581493A (en) | 2012-05-25 |
| US20150024450A1 (en) | 2015-01-22 |
| RU2009145274A (ru) | 2011-06-20 |
| EP2064225A4 (en) | 2010-03-03 |
| EP2511287A3 (en) | 2012-11-28 |
| BRPI0811556A2 (pt) | 2017-05-02 |
| JP2010526536A (ja) | 2010-08-05 |
| US20100297721A1 (en) | 2010-11-25 |
| ZA200908721B (en) | 2010-08-25 |
| RU2541785C2 (ru) | 2015-02-20 |
| WO2008141174A9 (en) | 2012-07-05 |
| EP2511285A3 (en) | 2012-11-28 |
| EP2511287A2 (en) | 2012-10-17 |
| WO2008141174A3 (en) | 2009-03-12 |
| EP2511284A2 (en) | 2012-10-17 |
| EP2064225A2 (en) | 2009-06-03 |
| AU2008251465A1 (en) | 2008-11-20 |
| EP2511286A3 (en) | 2012-11-28 |
| EP2511284A3 (en) | 2012-11-28 |
| EP2511285A2 (en) | 2012-10-17 |
| US8435770B2 (en) | 2013-05-07 |
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