KR20090109587A - 녹내장 또는 고안압 처리를 위한 감마-락탐 - Google Patents
녹내장 또는 고안압 처리를 위한 감마-락탐 Download PDFInfo
- Publication number
- KR20090109587A KR20090109587A KR1020097018979A KR20097018979A KR20090109587A KR 20090109587 A KR20090109587 A KR 20090109587A KR 1020097018979 A KR1020097018979 A KR 1020097018979A KR 20097018979 A KR20097018979 A KR 20097018979A KR 20090109587 A KR20090109587 A KR 20090109587A
- Authority
- KR
- South Korea
- Prior art keywords
- substituted
- another embodiment
- phenyl
- compound
- carbon atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
- C07D207/267—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US89018107P | 2007-02-15 | 2007-02-15 | |
| US60/890,181 | 2007-02-15 | ||
| PCT/US2008/053386 WO2008100809A1 (en) | 2007-02-15 | 2008-02-08 | Gamma-lactams for the treatment of glaucoma or elevated intraocular pressure |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20090109587A true KR20090109587A (ko) | 2009-10-20 |
Family
ID=39511007
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020097018979A Ceased KR20090109587A (ko) | 2007-02-15 | 2008-02-08 | 녹내장 또는 고안압 처리를 위한 감마-락탐 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8362054B2 (https=) |
| EP (1) | EP2118094B1 (https=) |
| JP (1) | JP5566696B2 (https=) |
| KR (1) | KR20090109587A (https=) |
| CN (1) | CN101657445B (https=) |
| AU (1) | AU2008216499B2 (https=) |
| BR (1) | BRPI0807600A2 (https=) |
| CA (1) | CA2678191A1 (https=) |
| ES (1) | ES2404169T3 (https=) |
| MX (1) | MX2009008734A (https=) |
| NZ (1) | NZ598945A (https=) |
| WO (1) | WO2008100809A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009055289A2 (en) * | 2007-10-23 | 2009-04-30 | Allergan, Inc. | Therapeutic substituted lactams |
| CN117500791A (zh) * | 2021-03-08 | 2024-02-02 | 阿比奥尼克斯制药公司 | 可用于治疗肝脏疾病的化合物 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2451392A1 (en) * | 2001-07-16 | 2003-01-30 | F. Hoffmann-La Roche Ag | Prostaglandin analogues as ep4 receptor agonists |
| KR100437972B1 (ko) * | 2001-10-27 | 2004-07-02 | 한국과학기술연구원 | 피롤리디논 유도체, 이의 제조 방법 및 이를 포함하는제약 조성물 |
| AU2003211574A1 (en) * | 2002-03-05 | 2003-09-16 | Ono Pharmaceutical Co., Ltd. | 8-azaprostaglandin derivative compounds and drugs containing the compounds as the active ingredient |
| US6573294B1 (en) * | 2002-05-14 | 2003-06-03 | Allergan, Inc. | 8-azaprostaglandin analogs as agents for lowering intraocular pressure |
| JP4754820B2 (ja) * | 2002-06-10 | 2011-08-24 | メルク セローノ ソシエテ アノニム | プロスタグランジン作動薬としてのγラクタムおよびその使用 |
| WO2004037813A1 (en) * | 2002-10-25 | 2004-05-06 | Merck Frosst Canada & Co. | Pyrrolidin-2-on derivatives as ep4 receptor agonists |
| US7091231B2 (en) | 2004-12-10 | 2006-08-15 | Allergan, Inc. | 12-Aryl prostaglandin analogs |
| JP2008538547A (ja) | 2005-03-09 | 2008-10-30 | ロジャー・ウィリアムズ・ホスピタル | 甲状腺刺激ホルモン放出ホルモン類縁体及び使用方法 |
| CA2599425C (en) * | 2005-03-10 | 2013-04-30 | Allergan, Inc. | Substituted gamma lactams as therapeutic agents |
| WO2007109578A2 (en) * | 2006-03-20 | 2007-09-27 | Allergan, Inc. | Substituted gamma lactams as prostaglandin ep2 agonists |
-
2008
- 2008-02-08 ES ES08729358T patent/ES2404169T3/es active Active
- 2008-02-08 US US12/527,155 patent/US8362054B2/en not_active Expired - Fee Related
- 2008-02-08 NZ NZ598945A patent/NZ598945A/xx not_active IP Right Cessation
- 2008-02-08 AU AU2008216499A patent/AU2008216499B2/en not_active Ceased
- 2008-02-08 JP JP2009549670A patent/JP5566696B2/ja not_active Expired - Fee Related
- 2008-02-08 EP EP08729358.5A patent/EP2118094B1/en not_active Not-in-force
- 2008-02-08 WO PCT/US2008/053386 patent/WO2008100809A1/en not_active Ceased
- 2008-02-08 MX MX2009008734A patent/MX2009008734A/es active IP Right Grant
- 2008-02-08 BR BRPI0807600-6A patent/BRPI0807600A2/pt not_active IP Right Cessation
- 2008-02-08 CN CN2008800120472A patent/CN101657445B/zh not_active Expired - Fee Related
- 2008-02-08 CA CA002678191A patent/CA2678191A1/en not_active Abandoned
- 2008-02-08 KR KR1020097018979A patent/KR20090109587A/ko not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| JP5566696B2 (ja) | 2014-08-06 |
| MX2009008734A (es) | 2009-08-25 |
| CN101657445B (zh) | 2013-06-05 |
| EP2118094A1 (en) | 2009-11-18 |
| AU2008216499B2 (en) | 2014-04-17 |
| AU2008216499A1 (en) | 2008-08-21 |
| ES2404169T3 (es) | 2013-05-24 |
| WO2008100809A1 (en) | 2008-08-21 |
| NZ598945A (en) | 2013-08-30 |
| CN101657445A (zh) | 2010-02-24 |
| CA2678191A1 (en) | 2008-08-21 |
| US8362054B2 (en) | 2013-01-29 |
| JP2010519208A (ja) | 2010-06-03 |
| BRPI0807600A2 (pt) | 2014-07-22 |
| US20100168189A1 (en) | 2010-07-01 |
| EP2118094B1 (en) | 2013-04-17 |
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| US7960381B2 (en) | Substituted gamma lactams as therapeutic agents | |
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| EP2029518A2 (en) | Cyclopentane-derivatives and their use as ocular hypotensive agents | |
| KR20090109587A (ko) | 녹내장 또는 고안압 처리를 위한 감마-락탐 | |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
Patent event date: 20090911 Patent event code: PA01051R01D Comment text: International Patent Application |
|
| PG1501 | Laying open of application | ||
| A201 | Request for examination | ||
| PA0201 | Request for examination |
Patent event code: PA02012R01D Patent event date: 20130122 Comment text: Request for Examination of Application |
|
| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 20140127 Patent event code: PE09021S01D |
|
| E601 | Decision to refuse application | ||
| PE0601 | Decision on rejection of patent |
Patent event date: 20140729 Comment text: Decision to Refuse Application Patent event code: PE06012S01D Patent event date: 20140127 Comment text: Notification of reason for refusal Patent event code: PE06011S01I |