KR20080086523A - 물질대사 장애의 치료용 화합물 - Google Patents
물질대사 장애의 치료용 화합물 Download PDFInfo
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- KR20080086523A KR20080086523A KR1020087018398A KR20087018398A KR20080086523A KR 20080086523 A KR20080086523 A KR 20080086523A KR 1020087018398 A KR1020087018398 A KR 1020087018398A KR 20087018398 A KR20087018398 A KR 20087018398A KR 20080086523 A KR20080086523 A KR 20080086523A
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- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
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- 229940096701 plain lipid modifying drug hmg coa reductase inhibitors Drugs 0.000 description 1
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- VVWRJUBEIPHGQF-UHFFFAOYSA-N propan-2-yl n-propan-2-yloxycarbonyliminocarbamate Chemical compound CC(C)OC(=O)N=NC(=O)OC(C)C VVWRJUBEIPHGQF-UHFFFAOYSA-N 0.000 description 1
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- 238000012216 screening Methods 0.000 description 1
- 125000002914 sec-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 1
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- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- ILMRJRBKQSSXGY-UHFFFAOYSA-N tert-butyl(dimethyl)silicon Chemical group C[Si](C)C(C)(C)C ILMRJRBKQSSXGY-UHFFFAOYSA-N 0.000 description 1
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- 150000001467 thiazolidinediones Chemical class 0.000 description 1
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- 239000003440 toxic substance Substances 0.000 description 1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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- Bioinformatics & Cheminformatics (AREA)
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- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
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- Neurology (AREA)
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- Gastroenterology & Hepatology (AREA)
- Dermatology (AREA)
- Vascular Medicine (AREA)
- Reproductive Health (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US76206806P | 2006-01-25 | 2006-01-25 | |
| US60/762,068 | 2006-01-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20080086523A true KR20080086523A (ko) | 2008-09-25 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| KR1020087018398A Ceased KR20080086523A (ko) | 2006-01-25 | 2007-01-22 | 물질대사 장애의 치료용 화합물 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7947735B2 (https=) |
| EP (1) | EP1976378A4 (https=) |
| JP (1) | JP2009528275A (https=) |
| KR (1) | KR20080086523A (https=) |
| CN (1) | CN101374415A (https=) |
| AU (1) | AU2007208127A1 (https=) |
| CA (1) | CA2636290A1 (https=) |
| IL (1) | IL192852A (https=) |
| NZ (1) | NZ569729A (https=) |
| WO (1) | WO2007087506A2 (https=) |
| ZA (1) | ZA200805645B (https=) |
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| MXPA05008600A (es) * | 2003-02-13 | 2005-11-04 | Wellstat Therapeutics Corp | Compuestos para el tratamiento de desordenes metabolicos. |
| CN1774244A (zh) * | 2003-04-15 | 2006-05-17 | 维尔斯达医疗公司 | 用于治疗代谢紊乱的化合物 |
| MXPA05011592A (es) * | 2003-04-30 | 2005-12-15 | Wellstat Therapeutics Corp | Compuestos para el tratamiento de trastornos metabolicos. |
| US20090176885A1 (en) * | 2006-02-02 | 2009-07-09 | Wellstat Therapeutics Corporation | Compounds for the treatment of metabolic disorders |
| KR20080106455A (ko) * | 2006-03-31 | 2008-12-05 | 웰스태트 테러퓨틱스 코포레이션 | 대사장애의 조합치료 |
| US7935689B2 (en) * | 2006-05-18 | 2011-05-03 | Wellstat Therapeutics Corporation | Compounds for the treatment of metabolic disorders |
| JP5252585B2 (ja) * | 2006-06-09 | 2013-07-31 | ウェルスタット セラピューティクス コーポレイション | 代謝障害の治療のための化合物 |
| WO2008022267A2 (en) * | 2006-08-17 | 2008-02-21 | Wellstat Therapeutics Corporation | Combination treatment for metabolic disorders |
| DE102007058842A1 (de) * | 2007-12-05 | 2009-06-10 | Grünenthal GmbH | Arzneimittel |
| JP5496913B2 (ja) * | 2008-01-15 | 2014-05-21 | ウェルスタット セラピューティクス コーポレイション | 代謝異常の治療のための化合物 |
| JP5339545B2 (ja) | 2008-03-13 | 2013-11-13 | ウェルスタット セラピューティクス コーポレイション | 尿酸を減少させる化合物及び方法 |
| WO2012033720A1 (en) | 2010-09-08 | 2012-03-15 | Wellstat Therapeutics Corporation | Benzoic acid compounds for reducing uric acid |
Family Cites Families (11)
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| FR5035M (https=) | 1964-07-28 | 1967-05-02 | ||
| US4080335A (en) * | 1975-07-28 | 1978-03-21 | Beecham Group Limited | Anorexic chromans |
| FR2653119B1 (fr) | 1989-10-18 | 1994-08-05 | Lipha | Nouveaux aryloxy alcoyl benzenes, leurs procedes de preparation et les compositions pharmaceutiques en renfermant. |
| MXPA03011558A (es) | 2001-06-12 | 2004-03-26 | Wellstat Therapeutics Corp | Compuestos para el tratamiento de desordenes metabolicos. |
| CA2502297C (en) | 2002-11-01 | 2011-12-13 | Wellstat Therapeutics Corporation | Compounds for the treatment of metabolic disorders |
| MXPA05008600A (es) | 2003-02-13 | 2005-11-04 | Wellstat Therapeutics Corp | Compuestos para el tratamiento de desordenes metabolicos. |
| CN1774244A (zh) | 2003-04-15 | 2006-05-17 | 维尔斯达医疗公司 | 用于治疗代谢紊乱的化合物 |
| CN1777576A (zh) | 2003-04-22 | 2006-05-24 | 维尔斯达医疗公司 | 用于治疗代谢紊乱的化合物 |
| MXPA05011592A (es) | 2003-04-30 | 2005-12-15 | Wellstat Therapeutics Corp | Compuestos para el tratamiento de trastornos metabolicos. |
| DE602004031954D1 (de) | 2003-08-20 | 2011-05-05 | Wellstat Therapeutics Corp | Verbindungen zur behandlung von stoffwechselstörungen |
| CA2547430A1 (en) * | 2003-11-26 | 2005-06-09 | Takeda Pharmaceutical Company Limited | Receptor function regulating agent |
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2007
- 2007-01-22 NZ NZ569729A patent/NZ569729A/en not_active IP Right Cessation
- 2007-01-22 EP EP07717341A patent/EP1976378A4/en not_active Withdrawn
- 2007-01-22 KR KR1020087018398A patent/KR20080086523A/ko not_active Ceased
- 2007-01-22 JP JP2008552537A patent/JP2009528275A/ja not_active Withdrawn
- 2007-01-22 CA CA002636290A patent/CA2636290A1/en not_active Abandoned
- 2007-01-22 AU AU2007208127A patent/AU2007208127A1/en not_active Abandoned
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- 2007-01-22 WO PCT/US2007/060833 patent/WO2007087506A2/en not_active Ceased
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2008
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- 2008-07-16 IL IL192852A patent/IL192852A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1976378A4 (en) | 2010-06-09 |
| IL192852A0 (en) | 2009-02-11 |
| CN101374415A (zh) | 2009-02-25 |
| WO2007087506A3 (en) | 2007-11-22 |
| EP1976378A2 (en) | 2008-10-08 |
| CA2636290A1 (en) | 2007-08-02 |
| WO2007087506A2 (en) | 2007-08-02 |
| US20080306150A1 (en) | 2008-12-11 |
| US7947735B2 (en) | 2011-05-24 |
| IL192852A (en) | 2012-03-29 |
| NZ569729A (en) | 2011-07-29 |
| AU2007208127A1 (en) | 2007-08-02 |
| ZA200805645B (en) | 2009-09-30 |
| JP2009528275A (ja) | 2009-08-06 |
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