KR20070107756A - 슈도모나스 애루기노사 혈청형 ｉａｔｓ ｏ１１의지질다당류에 특이적인 인간 단일 클론 항체 - Google Patents

슈도모나스 애루기노사 혈청형 ｉａｔｓ ｏ１１의지질다당류에 특이적인 인간 단일 클론 항체 Download PDF

Info

Publication number
KR20070107756A
KR20070107756A KR1020077020669A KR20077020669A KR20070107756A KR 20070107756 A KR20070107756 A KR 20070107756A KR 1020077020669 A KR1020077020669 A KR 1020077020669A KR 20077020669 A KR20077020669 A KR 20077020669A KR 20070107756 A KR20070107756 A KR 20070107756A
Authority
KR
South Korea
Prior art keywords
monoclonal antibody
human monoclonal
antibody
human
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020077020669A
Other languages
English (en)
Korean (ko)
Inventor
알로이스 비 랑
마이클 피. 호른
마틴 에이. 임보덴
아드라인 쭈에르체르
Original Assignee
켄타 바이오테크 아게
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 켄타 바이오테크 아게 filed Critical 켄타 바이오테크 아게
Publication of KR20070107756A publication Critical patent/KR20070107756A/ko
Ceased legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Gram-negative bacteria
    • C07K16/1214—Pseudomonadaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/40—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum bacterial
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77—Internalization into the cell

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Plant Pathology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
KR1020077020669A 2005-02-14 2006-02-13 슈도모나스 애루기노사 혈청형 ｉａｔｓ ｏ１１의지질다당류에 특이적인 인간 단일 클론 항체 Ceased KR20070107756A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05003095A EP1690875A1 (en) 2005-02-14 2005-02-14 Human monoclonal antibody specific for lipopolysaccharides (LPS) of the pseudomonas aeruginosa IATS O11 serotype
EP05003095.6 2005-02-14

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020137000972A Division KR20130018991A (ko) 2005-02-14 2006-02-13 슈도모나스 애루기노사 혈청형 ｉａｔｓ ｏ１１의 지질다당류에 특이적인 인간 단일 클론 항체

Publications (1)

Publication Number Publication Date
KR20070107756A true KR20070107756A (ko) 2007-11-07

Family

ID=34933741

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020077020669A Ceased KR20070107756A (ko) 2005-02-14 2006-02-13 슈도모나스 애루기노사 혈청형 ｉａｔｓ ｏ１１의지질다당류에 특이적인 인간 단일 클론 항체
KR1020137000972A Ceased KR20130018991A (ko) 2005-02-14 2006-02-13 슈도모나스 애루기노사 혈청형 ｉａｔｓ ｏ１１의 지질다당류에 특이적인 인간 단일 클론 항체

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020137000972A Ceased KR20130018991A (ko) 2005-02-14 2006-02-13 슈도모나스 애루기노사 혈청형 ｉａｔｓ ｏ１１의 지질다당류에 특이적인 인간 단일 클론 항체

Country Status (11)

Country Link
US (1) US8197816B2 (https=)
EP (2) EP1690875A1 (https=)
JP (1) JP4944799B2 (https=)
KR (2) KR20070107756A (https=)
CN (1) CN101120018B (https=)
AT (1) ATE480563T1 (https=)
CA (1) CA2597701C (https=)
DE (1) DE602006016736D1 (https=)
ES (1) ES2348263T3 (https=)
IL (1) IL184774A (https=)
WO (1) WO2006084758A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2571673A1 (en) * 2004-06-28 2006-01-05 Proteome Systems Intellectual Property Pty Ltd Novel methods of diagnosis of treatment of p. aeruginosa infection and reagents therefor
EP2417157A1 (en) * 2009-04-09 2012-02-15 Kenta Biotech AG Human monoclonal antibody specific for lipolysaccarides (lps) of serotype lats 01 of pseudomonas aeruginosa
KR20120128686A (ko) * 2010-02-18 2012-11-27 심포젠 에이/에스 녹농균의 혈청형 ａ 지질다당류에 대한 항체
EP2361989A1 (en) * 2010-02-26 2011-08-31 Kenta Biotech AG Assays and kits for serotyping Pseudomonas aeruginosa and oligonucleotide sequences useful in such methods and kits
CA2925897A1 (en) * 2013-09-30 2015-04-02 Daiichi Sankyo Company, Limited Anti-lps o11 antibody
WO2017083515A2 (en) 2015-11-10 2017-05-18 Visterra, Inc. Antibody molecule-drug conjugates and uses thereof
JP7303110B2 (ja) 2017-01-18 2023-07-04 ビステラ， インコーポレイテッド 抗体分子－薬物コンジュゲートおよびその使用
KR20240085798A (ko) 2020-04-03 2024-06-17 비스테라, 인크. 항체 분자-약물 접합체 및 이의 용도
EP4512826A3 (en) 2021-07-09 2025-04-02 Luxembourg Institute Of Health (LIH) Dimeric protein complexes and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ218499A (en) * 1985-12-10 1990-04-26 Genetic Systems Corp Monoclonal antibodies against pseudomonas aeruginosa, pharmaceutical compositions and detection methods
JP4398620B2 (ja) 2000-02-03 2010-01-13 ミレニアム・ファーマシューティカルズ・インコーポレイテッド ヒト化抗ｃｃｒ−２抗体およびその使用方法
EP1319025A2 (en) * 2000-09-07 2003-06-18 John R. Schreiber Human antibodies against pseudomonas aeruginosa lps derived from transgenic xenomouse

Also Published As

Publication number Publication date
EP1690875A1 (en) 2006-08-16
JP2008530988A (ja) 2008-08-14
DE602006016736D1 (de) 2010-10-21
ATE480563T1 (de) 2010-09-15
IL184774A0 (en) 2007-12-03
EP1848741A1 (en) 2007-10-31
US20090068191A1 (en) 2009-03-12
EP1848741B1 (en) 2010-09-08
ES2348263T3 (es) 2010-12-02
KR20130018991A (ko) 2013-02-25
JP4944799B2 (ja) 2012-06-06
CA2597701A1 (en) 2006-08-17
CN101120018B (zh) 2012-07-25
CN101120018A (zh) 2008-02-06
IL184774A (en) 2012-01-31
US8197816B2 (en) 2012-06-12
CA2597701C (en) 2012-01-10
WO2006084758A1 (en) 2006-08-17

Similar Documents

Publication Publication Date Title
IL184774A (en) Human monoclonal antibody specific for lipopolysaccharides (lps) of the pseudomonas aeruginosa iats 011 serotype
KR20220128332A (ko) Lilrb2에 대항하는 단일-도메인 항체
KR100910097B1 (ko) 슈도모나스 애루기노사 혈청형 ｉａｔｓ ｏ６의지질다당류에 특이적인 사람 단일 클론 항체
JPH07501806A (ja) ヒトｐｄｇｆベータ・レセプタに対する阻害性免疫グロブリン・ポリペプチド
JP2012523221A (ja) 緑膿菌（Ｐｓｅｕｄｏｍｏｎａｓａｅｒｕｇｉｎｏｓａ）のＩＡＴＳＯ１血清型のリポ多糖類（ＬＰＳ）に対して特異的なヒトモノクローナル抗体
US20240059764A1 (en) ANTIGEN-BINDING PROTEIN TARGETING STAPHYLOCOCCUS AUREUS a-HEMOLYSIS AND APPLICATION THEREOF
CN114957460A (zh) 交叉中和金黄色葡萄球菌毒素的抗原结合蛋白及其用途
CN120040587B (zh) 抗liv-1抗体或其抗原结合片段及其用途
US20240317885A1 (en) Anti-tax interacting protein-1 (tip1) binding molecules
WO2004020574A2 (en) Scfv fragment to human cathepsin l and methods of use
WO2022199527A1 (zh) 靶向肺炎链球菌溶血素的抗原结合蛋白及其用途
US7250164B2 (en) Vaccine composition for preventing meningococcal disease
CN121851178A (zh) 靶向pvrig和pdl1的双特异性抗体及其应用

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20070910

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
A201 Request for examination
AMND Amendment
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20100730

Comment text: Request for Examination of Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20120612

Patent event code: PE09021S01D

AMND Amendment
E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 20121122

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 20120612

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I

J201 Request for trial against refusal decision
PJ0201 Trial against decision of rejection

Patent event date: 20121221

Comment text: Request for Trial against Decision on Refusal

Patent event code: PJ02012R01D

Patent event date: 20121122

Comment text: Decision to Refuse Application

Patent event code: PJ02011S01I

Appeal kind category: Appeal against decision to decline refusal

Decision date: 20131021

Appeal identifier: 2012101010740

Request date: 20121221

AMND Amendment
A107 Divisional application of patent
PA0104 Divisional application for international application

Comment text: Divisional Application for International Patent

Patent event code: PA01041R01D

Patent event date: 20130114

PB0901 Examination by re-examination before a trial

Comment text: Amendment to Specification, etc.

Patent event date: 20130109

Patent event code: PB09011R02I

Comment text: Request for Trial against Decision on Refusal

Patent event date: 20121221

Patent event code: PB09011R01I

Comment text: Amendment to Specification, etc.

Patent event date: 20120731

Patent event code: PB09011R02I

Comment text: Amendment to Specification, etc.

Patent event date: 20100730

Patent event code: PB09011R02I

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20130206

Patent event code: PE09021S01D

B601 Maintenance of original decision after re-examination before a trial
PB0601 Maintenance of original decision after re-examination before a trial

Comment text: Report of Result of Re-examination before a Trial

Patent event code: PB06011S01D

Patent event date: 20131004

J121 Written withdrawal of request for trial
PC1202 Submission of document of withdrawal before decision of registration

Comment text: [Withdrawal of Procedure relating to Patent, etc.] Withdrawal (Abandonment)

Patent event code: PC12021R01D

Patent event date: 20131021

PJ1201 Withdrawal of trial

Patent event code: PJ12011R01D

Patent event date: 20131021

Comment text: Written Withdrawal of Request for Trial

Appeal identifier: 2012101010740

Request date: 20121221

Appeal kind category: Appeal against decision to decline refusal

Decision date: 20131021

WITB Written withdrawal of application