KR20070104563A - 생물학적 존재의 제어된 방출 - Google Patents
생물학적 존재의 제어된 방출 Download PDFInfo
- Publication number
- KR20070104563A KR20070104563A KR1020077016764A KR20077016764A KR20070104563A KR 20070104563 A KR20070104563 A KR 20070104563A KR 1020077016764 A KR1020077016764 A KR 1020077016764A KR 20077016764 A KR20077016764 A KR 20077016764A KR 20070104563 A KR20070104563 A KR 20070104563A
- Authority
- KR
- South Korea
- Prior art keywords
- emulsion
- particles
- biological presence
- biological
- particle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4826—Trypsin (3.4.21.4) Chymotrypsin (3.4.21.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/50—Hydrolases (3) acting on carbon-nitrogen bonds, other than peptide bonds (3.5), e.g. asparaginase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
- B01J2/02—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
- B01J2/06—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops in a liquid medium
- B01J2/08—Gelation of a colloidal solution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/501—Inorganic compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21001—Chymotrypsin (3.4.21.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21062—Subtilisin (3.4.21.62)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
- C12Y305/01—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amides (3.5.1)
- C12Y305/01005—Urease (3.5.1.5)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Marine Sciences & Fisheries (AREA)
- Zoology (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2004907219 | 2004-12-20 | ||
| AU2004907219A AU2004907219A0 (en) | 2004-12-20 | Controlled release of biological entities |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20070104563A true KR20070104563A (ko) | 2007-10-26 |
Family
ID=36601253
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020077016764A Ceased KR20070104563A (ko) | 2004-12-20 | 2005-12-20 | 생물학적 존재의 제어된 방출 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US8992986B2 (enExample) |
| EP (1) | EP1838289B1 (enExample) |
| JP (2) | JP5593030B2 (enExample) |
| KR (1) | KR20070104563A (enExample) |
| CN (1) | CN101106978A (enExample) |
| BR (1) | BRPI0519139A2 (enExample) |
| CA (1) | CA2591344C (enExample) |
| MX (1) | MX2007007373A (enExample) |
| NZ (1) | NZ556082A (enExample) |
| WO (1) | WO2006066317A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6101683A (en) | 1998-04-02 | 2000-08-15 | Avery Dennison Corporation | Loop fastener, fastener clip including same and loop fastener dispensing tool |
| WO2009132411A1 (en) * | 2008-04-28 | 2009-11-05 | The University Of British Columbia | Polymer-free drug delivery system for implantable medical devices |
| US9222060B2 (en) | 2009-03-27 | 2015-12-29 | Australian Nuclear Science And Technology Organisation | Triggered release |
| KR102369175B1 (ko) * | 2010-08-16 | 2022-03-02 | 오스트레일리안 뉴클리어 사이언스 앤드 테크놀로지 오가니제이션 | 생체분자의 전달을 위한 세라믹 입자를 포함하는 미립자 물질 및 미립자 물질을 포함하는 약학적 조성물 |
| US10001501B2 (en) | 2015-12-31 | 2018-06-19 | Universal Diagnostics, S. L. | Systems and methods for automated, customizable sample preparation for detection of metabolites and lipids |
| CN107522868B (zh) * | 2017-10-16 | 2021-01-08 | 湖北工业大学 | 环氧纳米二氧化硅/嵌段聚合物复合乳液的制备方法 |
| US11541105B2 (en) | 2018-06-01 | 2023-01-03 | The Research Foundation For The State University Of New York | Compositions and methods for disrupting biofilm formation and maintenance |
| EP3831365A4 (en) * | 2018-08-03 | 2023-05-10 | Lemonex Inc. | PHARMACEUTICAL COMPOSITION FOR THE PREVENTION OR TREATMENT OF ATOPIC DISEASES |
| IT202000011803A1 (it) * | 2020-05-20 | 2021-11-20 | Hudson River Biotechnology B V | Particella multistrato incapsulante una molecola biologicamente attiva |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3850751A (en) * | 1973-02-16 | 1974-11-26 | Corning Glass Works | Enzymes immobilized on porous inorganic support materials |
| CH624011A5 (enExample) * | 1977-08-05 | 1981-07-15 | Battelle Memorial Institute | |
| CA1253129A (en) * | 1984-02-09 | 1989-04-25 | Thomas R. Jones | Porous inorganic materials |
| JPH0717371B2 (ja) * | 1986-09-05 | 1995-03-01 | 株式会社資生堂 | 球状の有機複合粘土鉱物及びその製造法 |
| JPH05261274A (ja) * | 1992-03-23 | 1993-10-12 | Lion Corp | 金属化合物の球形粒子の製造方法 |
| EP0672117A4 (en) * | 1992-08-13 | 1996-06-12 | Univ Pennsylvania | MATRIX BASED ON A BIOACTIVE MATERIAL FOR THE SYNTHESIS -i (IN VITRO) OF BONE TISSUE. |
| US5817327A (en) * | 1994-07-27 | 1998-10-06 | The Trustees Of The University Of Pennsylvania | Incorporation of biologically active molecules into bioactive glasses |
| US6096324A (en) * | 1995-06-13 | 2000-08-01 | Laboratory Skin Care | Methods of delivering materials into the skin, and compositions used therein |
| US6764690B2 (en) * | 1996-05-29 | 2004-07-20 | Delsitech Oy | Dissolvable oxides for biological applications |
| US5972384A (en) * | 1997-10-01 | 1999-10-26 | University Of Maryland, Baltimore | Use of biologically active glass as a drug delivery system |
| JP4920132B2 (ja) | 1998-08-13 | 2012-04-18 | ゾル−ゲル テクノロジーズ エルティーディー. | 機能性分子により充填されたオキシドマイクロカプセルの調製のための方法およびそれにより得られた生産物 |
| AU772153B2 (en) * | 1999-02-12 | 2004-04-08 | Molecular Insight Pharmaceuticals, Inc. | Matrices for drug delivery and methods for making and using the same |
| AU775800B2 (en) | 1999-06-24 | 2004-08-19 | Christopher V. W. Hogue | Incorporation and applications of biomolecular interactions within a carrier |
| JP2001038193A (ja) * | 1999-07-28 | 2001-02-13 | Nippon Millipore Kk | 複合シリカマイクロカプセルの製造方法と複合シリカマイクロカプセルの芯物質の固定化と徐放作用の制御方法。 |
| CA2380941A1 (en) | 1999-08-16 | 2001-02-22 | Henceforth Hibernia, Inc. | Therapeutic and prophylactic compositions including catalytic biomimetic solids and methods to prepare and use them |
| AUPQ573300A0 (en) | 2000-02-21 | 2000-03-16 | Australian Nuclear Science & Technology Organisation | Controlled release ceramic particles, compositions thereof, processes of preparation and methods of use |
| US6303290B1 (en) * | 2000-09-13 | 2001-10-16 | The Trustees Of The University Of Pennsylvania | Encapsulation of biomaterials in porous glass-like matrices prepared via an aqueous colloidal sol-gel process |
| US6544497B2 (en) * | 2001-02-15 | 2003-04-08 | Aeropharm Technology Incorporated | Modulated release particles for aerosol delivery |
| US6596262B2 (en) * | 2001-02-15 | 2003-07-22 | Aeropharm Technology Incorporated | Modulated release particles for aerosol delivery |
| US6485707B2 (en) * | 2001-02-15 | 2002-11-26 | Aeropharm Technology Incorporated | Modulated release particles for aerosol delivery |
| JP2005511629A (ja) * | 2001-11-20 | 2005-04-28 | アドバンスト インハレーション リサーチ,インコーポレイテッド | 持続作用生成物送達用組成物 |
| JP4192235B2 (ja) * | 2002-04-30 | 2008-12-10 | 独立行政法人産業技術総合研究所 | 徐放機能を有するメソポーラス無機材料 |
| US7399495B2 (en) * | 2002-04-30 | 2008-07-15 | Solae, Llc | Protein product imparting high water dispersibility |
| US20060127480A1 (en) * | 2002-10-11 | 2006-06-15 | Michael Tobyn | Pharmaceutical excipients comprising inorganic particles in association with an organic polymeric material and forming a solid reticulated matrix, compositions, manufacturing and use thereof |
| US20040180091A1 (en) * | 2003-03-13 | 2004-09-16 | Chang-Yi Lin | Carbonated hydroxyapatite-based microspherical composites for biomedical uses |
| JP2005307120A (ja) * | 2004-04-26 | 2005-11-04 | Mitsubishi Chemicals Corp | 徐放剤及びそれを用いた徐放材 |
| US20090098044A1 (en) * | 2004-11-15 | 2009-04-16 | Australian Nuclear Science And Technology Organisation | Solid particles from controlled destabilisation of microemulsions |
| KR20070097439A (ko) * | 2004-11-15 | 2007-10-04 | 오스트레일리언뉴클리어사이언스앤드테크놀로지오거나이제이션 | 마이크로에멀션의 제어된 비안정화로부터 제조된 고형분입자 |
-
2005
- 2005-12-20 US US11/721,728 patent/US8992986B2/en not_active Expired - Fee Related
- 2005-12-20 NZ NZ556082A patent/NZ556082A/en not_active IP Right Cessation
- 2005-12-20 JP JP2008518535A patent/JP5593030B2/ja not_active Expired - Fee Related
- 2005-12-20 CA CA2591344A patent/CA2591344C/en not_active Expired - Lifetime
- 2005-12-20 WO PCT/AU2005/001915 patent/WO2006066317A1/en not_active Ceased
- 2005-12-20 BR BRPI0519139-4A patent/BRPI0519139A2/pt not_active Application Discontinuation
- 2005-12-20 CN CNA2005800470576A patent/CN101106978A/zh active Pending
- 2005-12-20 MX MX2007007373A patent/MX2007007373A/es active IP Right Grant
- 2005-12-20 KR KR1020077016764A patent/KR20070104563A/ko not_active Ceased
- 2005-12-20 EP EP05818407.8A patent/EP1838289B1/en not_active Expired - Lifetime
-
2012
- 2012-11-05 JP JP2012243686A patent/JP5727445B2/ja not_active Expired - Fee Related
-
2015
- 2015-02-03 US US14/612,739 patent/US9717688B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP5727445B2 (ja) | 2015-06-03 |
| WO2006066317A8 (en) | 2006-08-24 |
| EP1838289A4 (en) | 2011-12-14 |
| BRPI0519139A2 (pt) | 2008-12-30 |
| US9717688B2 (en) | 2017-08-01 |
| MX2007007373A (es) | 2007-08-14 |
| WO2006066317A1 (en) | 2006-06-29 |
| US8992986B2 (en) | 2015-03-31 |
| JP2008538217A (ja) | 2008-10-16 |
| EP1838289A1 (en) | 2007-10-03 |
| JP5593030B2 (ja) | 2014-09-17 |
| US20150147401A1 (en) | 2015-05-28 |
| US20090252808A1 (en) | 2009-10-08 |
| CA2591344A1 (en) | 2006-06-29 |
| CA2591344C (en) | 2015-09-29 |
| EP1838289B1 (en) | 2017-12-13 |
| JP2013047264A (ja) | 2013-03-07 |
| CN101106978A (zh) | 2008-01-16 |
| NZ556082A (en) | 2009-09-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
Patent event date: 20070720 Patent event code: PA01051R01D Comment text: International Patent Application |
|
| PG1501 | Laying open of application | ||
| A201 | Request for examination | ||
| PA0201 | Request for examination |
Patent event code: PA02012R01D Patent event date: 20081222 Comment text: Request for Examination of Application |
|
| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 20110216 Patent event code: PE09021S01D |
|
| AMND | Amendment | ||
| E601 | Decision to refuse application | ||
| PE0601 | Decision on rejection of patent |
Patent event date: 20111025 Comment text: Decision to Refuse Application Patent event code: PE06012S01D Patent event date: 20110216 Comment text: Notification of reason for refusal Patent event code: PE06011S01I |
|
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