KR20070062799A - Scalp-care shampoo composition - Google Patents

Abstract

A shampoo composition for scalp care is provided to increase production of coacervate which is capable of preventing and treating scalp troubles including dandruff, scalp stimulation and itching, and improve adsorption of the coacervate to the scalp and hairs. The shampoo composition for scalp care comprises an anionic surfactant, 0.01-5 wt.% of a cationic polymer, 0.001-5 wt.% of an agent for preventing and treating scalp troubles, and 0.1-10 wt.% of a tertiary ammonium cationic surfactant represented by the formula(1), wherein R is C12-C22 linear alkyl group, branched alkyl group, alkenyl group or alkylamide, n is an integer from 0 to 10, and X is halogen element, sulfate group or acetate group; and the agent for preventing and treating scalp troubles is zinc pyrithione, selenium sulfide, climbazole, tar, sulfur, salicylic acid, water-insoluble licorice acid, plant-extracted oil phase component and its derivatives.

Description

Scalp-care shampoo composition

The present invention relates to a shampoo composition for treating scalp problems with an increased amount of coacervate produced by an anionic detergent and a cationic polymer.

In general, the shampoo commonly used to remove the contamination of the hair and scalp to keep clean and beautiful, contains an anionic surfactant having excellent cleaning power as a main component. Recently, the number of people with scalp problems such as dandruff and scalp itch have gradually increased due to various factors such as physical, chemical, and environmental. Therefore, as one of various attempts to solve this problem, anti-dandruff, antibacterial, and scalp irritation were removed. Various products have been studied for adding additional ingredients such as anti-itch, or for use before or after shampooing.

However, in the case of a cleaning product such as a shampoo, the characteristics of the product are strong, so the amount of the active ingredient actually adsorbed to the hair or scalp is extremely small, and therefore, the effect and sustainability are limited.

Therefore, in order to solve these problems, there has been a continuous study of detergents or cosmetics to keep these active ingredients in hair and scalp for a long time after cleaning. Recently, U.S. Patent Publication No. 2003/0199403 attempts to increase the adsorption of solid particle components effective for hair and scalp by coacervates produced by anionic surfactants and cationic polymers. In 2004/0146475, studies have been conducted to enhance the formation of coacervates in conditioning shampoos through the appropriate combination of ethoxy and sulfate levels of cationic cellulose polymers and anionic surfactants.

However, since they produce coacervates by simple combinations of anionic detergents and cationic polymers, there is a limit to the amount of coacervates produced, and thus it is not easy to increase the adsorption of active ingredients to improve the effect and its sustainability.

Accordingly, the technical problem to be achieved by the present invention is to maximize the coacervate formation to enhance the hair and / or scalp adsorption effect of the scalp trouble prevention or treatment of such dandruff, breeding, scalp irritation, itching by coacervate, and continuously The present invention provides a shampoo composition for scalp care that can exert an effect.

In order to achieve the above technical problem, the present invention is a scalp shampoo composition comprising an anionic surfactant and a cationic polymer,

Scalp trouble prevention or treatment; And it provides a shampoo composition for scalp comprising a quaternary ammonium cation surfactant represented by the formula (1).

In Formula 1, R is any one selected from the group consisting of a linear alkyl group having 12 to 22 carbon atoms, branched alkyl group, alkenyl group and alkylamide, n is an integer of 0 to 10, X is a halogen group element, sulfate Any one selected from the group consisting of a group and an acetate group.

More preferably, the present invention provides a shampoo composition for scalp, characterized in that the content of the quaternary ammonium cation surfactant in the aforementioned scalp shampoo composition is 0.1 to 10% by weight based on the total weight of the composition.

More preferably, the present invention, the scalp shampoo composition, the scalp trouble prevention or treatment agent is zinc pyrithione, selenium sulfide, pyroxtonolamine, klimbazole, tar, sulfur, salicylic acid, oil-soluble licorice, plant extract It provides an shampoo composition for scalp, characterized in that any one or more selected from the group consisting of oil phase components, mineral extraction oil phase components and derivatives thereof.

More preferably, the present invention provides a scalp shampoo composition, characterized in that the content of the scalp preventive or therapeutic agent in the scalp shampoo composition is 0.001 to 5% by weight based on the total weight of the composition.

More preferably, the present invention provides a shampoo composition for scalp, characterized in that the content of the cationic polymer in the aforementioned shampoo composition for scalp is 0.01 to 5% by weight relative to the total weight of the composition.

Hereinafter, the shampoo composition for scalp of the present invention will be described in more detail.

Shampoo composition for scalp of the present invention includes a cationic surfactant introduced with a glyceryl group represented by the formula (1) as a base for enhancing coacetate formation.

Referring to Chemical Formula 1, the cationic surfactant used in the present invention is a structure of a quaternary ammonium compound, one of substituents of ammonium ions essentially consisting of alkylamidopropyl groups, and the other is a repeating unit with a hydrophilic group. Glyceryl group having 1 to 11 is condensed to have a hydrophilic group of the repeating structure, the remaining two substituents are composed of a methyl group.

The quaternary ammonium cationic surfactant contains at least one glyceryl group, which is a hydrophilic group, and interacts with anionic surfactants in an aqueous solution commonly referred to as a pseudo-nonionic complex surfactant. Melting mixed micelles can be formed. Since the pseudo-nonionic complex surfactant improves the problems of high viscosity and precipitation that occur when the cationic polymer and the anionic surfactant are used at the same time, the amount of the cationic polymer is increased even in the presence of the anionic surfactant. This can increase the amount of coacervate formed.

In addition, the quaternary ammonium cationic surfactant of Formula 1 includes an alkylamido group having a relatively hydrophilic property instead of a long-chain fatty acid group, so that the mixed micelle-forming ability of a pseudo-nonionic complex surfactant is better. In addition, even in the presence of anionic surfactants, the amount of cationic polymer used may be further increased, and as a result, it may have a special function of generating more coacervates, which are complexes of anionic surfactants and cationic polymers.

The quaternary ammonium cationic surfactant is preferably used 0.1 to 10% by weight based on the total weight of the composition. If the content is less than 0.1% by weight, it is difficult to achieve coacervate formation and stability improvement effect by the quaternary ammonium cation surfactant, and when the content is more than 10% by weight, the hair becomes damp and there is a concern about precipitation and phase stability. May not be suitable for use.

The shampoo composition for scalp according to the present invention essentially comprises a cationic polymer to produce coacervate. Coacervates are affected by various factors, but are known to be most affected by the structure of cationic polymers, in particular the molecular weight and positive charge density (mEq / g) of cationic polymers.

The cationic polymer is not particularly limited as long as it can be used in a conventional shampoo composition, for example, may be used by selecting one or more from the group consisting of natural cationic polymer, synthetic cationic polymer and mixtures thereof. .

Examples of the natural cationic polymer that can be used in the present invention include cationic guar such as guar hydroxypropyltrimonium chloride and hydroxypropyl guar hydroxypropyltrimonium chloride, cellulose (polyquaternium-10), and the like. One or more may be used, but is not limited thereto.

Synthetic cationic polymers that can be used in the present invention include, for example, dimethyldiallylammonium chloride polymer, acrylamide-dimethyldiallylammonium chloride copolymer, PVP-dimethylaminoethylmethacrylate copolymer, acrylic acid-dimethyldi Allyl ammonium chloride copolymer, acrylamide-dimethylamino ethyl methacrylate methyl chloride copolymer, trimethylaminoethyl methacrylate polymer and the like may be used, but are not limited thereto.

In the shampoo composition for scalp of the present invention, the content of the cationic polymer is preferably 0.01 to 5% by weight based on the total weight of the composition. If the content is less than 0.01% by weight, the production of coacervate is low, and the adsorption of the scalp trouble prevention or treatment agent is less, so that the effects of anti-dandruff, antibacterial, scalp itch improvement, and scalp irritation are not sufficiently exhibited. If exceeded, excessive production of coacervate may cause these ingredients to adsorb excessively on the hair and scalp, resulting in a bad shampoo.

Shampoo composition for scalp according to the present invention is a component for preventing or treating scalp irritation such as dandruff, rash and scalp irritation, itching, etc. zinc pyrithione, selenium sulfide, pyroxtonolamine, klimbazole, tar, sulfur, salicylic acid, Oil-soluble licorice, oily components extracted from plants, oily components extracted from minerals or derivatives thereof may be used alone or in combination, but is not limited thereto.

In addition, the content of such scalp trouble prevention or treatment is preferably 0.001 to 5% by weight based on the total weight of the composition. If the content is less than 0.001% by weight, the absolute amount of the active ingredient is small, so that the prevention or treatment effect of the scalp trouble is not sufficiently exerted, and when it exceeds 5% by weight, these ingredients are excessively adsorbed on the hair and the scalp, resulting in bad feeling Because there is a concern.

The shampoo composition for scalp according to the present invention comprises an anionic surfactant as a cleaning component.

The anionic surfactant that can be used in the present invention is not particularly limited as long as it can be used in a conventional shampoo composition, the content of the anionic surfactant is preferably 1 to 50% by weight relative to the total weight of the composition. This is because the content is less than 1% by weight does not exert a cleaning function properly, when the content exceeds 50% by weight is too much cleaning power can give a rough feeling to the hair and scalp.

As the anionic surfactant that can be used in the present invention, for example, sodium lauryl sulfate, ammonium lauryl sulfate, magnesium lauryl sulfate, lauryl triethanolamine, sodium polyoxyethylene lauryl sulfate, polyoxyethylene lauryl sulfate Ammonium and the like may be used one or more, but is not limited thereto.

The shampoo composition for scalp of the present invention may further contain a nonionic surfactant and / or amphoteric surfactant within the scope of not impairing the object of the present invention for the purpose of increasing the cleaning power and the like.

As the nonionic surfactant that may be used in the present invention, for example, lauryl acid diethanolamide, palm oil fatty acid diethanolamide, palm oil fatty acid monoethanolamide, and the like may be used, but are not limited thereto.

As the amphoteric surfactant that can be used in the present invention, for example, betaine, amido propyl betaine, coco amppocarboxy glycinate, sacosinate, and the like may be used, but are not limited thereto. .

Shampoo composition for scalp according to the present invention may further comprise a conditioning component such as silicone compound, oily oil component within the scope that does not impair the object of the present invention.

Silicone compounds that can be used as conditioning ingredients in the present invention are not particularly limited as long as they can be used in shampoo compositions, for example, water insoluble non-volatile dimethicone, cyclomethicone, aminated silicone, trimethylsilyl One or more components commonly referred to as silicones such as moditicone and vinyl silicone and derivatives thereof can be used.

Oily oil components that can be used as conditioning components in the present invention include hydrocarbon oils and synthetic ester oils. Hydrocarbon oils include liquid paraffin (Mineral Oil), isoparaffin, and the like hydrogenated polydecene (Hydrogenated Polydecene), ester oils include myristic acid isopropyl, palmitic acid isopropyl, stearic acid, isostearyl, C _{12 -15-alkyl} benzoate Etc.

In addition, the shampoo composition for scalp according to the present invention may further contain additives such as preservatives, thickeners, viscosity adjusters, pH adjusters, fragrances, dyes, conditioning agents that can be used as a component of the shampoo composition, these, Can be easily purchased and used commercially. Examples of the preservative include methyl paraoxybenzoate, methylchloroisothiazolinone and a mixture of methylisothiazolinone (trade name: Kathon CG, manufactured by Rohm & Haas, USA). Examples of the thickener and the viscosity modifier include hydroxypropyl methyl cellulose, hydroxymethyl cellulose, sodium chloride, ammonium chloride, propylene glycol, hexylene glycol, and the like. Citric acid, sodium hydroxide, triethanolamine, etc. are mentioned as a pH adjuster. Examples of the dyes include water-soluble tar pigments. Conditioning agents include animal and vegetable extracts, proteins and protein variants, and Fatty Acid.

Hereinafter, the present invention will be described in detail with reference to Examples. However, embodiments according to the present invention can be modified in many different forms, the scope of the present invention should not be construed as limited to the embodiments described below. The embodiments of the present invention are provided to more completely explain the present invention to those skilled in the art.

<Synthesis of Quaternary Ammonium Cationic Surfactants of the Present Invention>

As a cationic surfactant in the form of quaternary ammonium, a monotype containing one quaternary ammonium group was synthesized in the following manner. The following examples are intended to illustrate the invention in detail, and these examples do not limit the technical scope of the invention.

N, N-dimethyl-N- Glyceryl Stearyl Amidopropyl Ammonium  Synthesis of Chloride

Isopropyl alcohol and alkylamidopropylamine and the equivalent of 1-chloro-2,3-propanediol were added to a three-necked flask, and sodium iodide was added as a catalyst and then refluxed. The reaction progress was checked by measuring the amine%. The reaction proceeded 95% by raising the temperature of the reactor to 120 ° C. and reacting for 10 hours. The reaction product was poured into acetone, cooled and recrystallized. The result was hygroscopic, and the result obtained through the manure after recrystallization was immediately dried in vacuo.

N, N-dimethyl-N- Diglyceryl Stearyl Amidopropyl Ammonium  Synthesis of Chloride

In order to synthesize the diglyceryl compound in which two glyceryl groups were substituted, the glyceryl group was further introduced in the monoglyceryl compound. Isopropyl alcohol, a monoglyceryl compound, and glycidol were added to a three-necked flask, followed by stirring at 50 ° C. for 1 hour to complete the reaction. Isopropyl alcohol was removed from the mixture by distillation under reduced pressure. Since the result was hygroscopic, the result was stored in distilled water 50% solution.

<Preparation of Examples 1 to 4>

To prepare a shampoo composition for scalp care composition and content shown in Table 1 below. After dissolving and dissolving zinc pyrithione as an anti-dandruff component in distilled water, polyquaternium-10 or guar hydroxypropyltrimonium chloride was dispersed and dissolved as a cationic polymer, respectively, and the quaternary ammonium cation interface represented by the following Chemical Formulas 2 to 5 After adding the active agent, anionic surfactant sodium lauryl sulfate and polyoxyethylene lauryl sulfate as a cleaning surfactant were added, and a palm oil fatty acid diethanolamide as a cleaning surfactant was added, and then dimethicone was added and stirred for 30 minutes. I was. After stirring, a pearl composition, a pigment, a preservative, and a perfume prepared in advance were added, and sodium chloride for forming an appropriate viscosity and citric acid for adjusting pH were added, followed by stirring for 30 minutes to prepare a test shampoo.

The pearl composition included in the shampoo was prepared separately as follows. 50% by weight of 30% ammonium lauryl sulfate as anionic surfactant, 5% by weight of palm oil fatty acid monoethanolamide as a nonionic surfactant, 10% by weight of ethylene glycol distearate as a pearling agent and 35% by weight of distilled water After warming to 75 ° C., the mixture was stirred for 5 minutes to dissolve uniformly, and then cooled to 45 ° C. to prepare a pearl composition.

In Formula 2, R is alkyl having 17 carbon atoms, and n is an integer of 0.

In Formula 3, R is alkyl having 17 carbon atoms, and n is an integer of 5.

In Chemical Formula 4, R is alkyl having 21 carbon atoms, and n is an integer of 0.

In Formula 5, R is alkyl having 21 carbon atoms, n is an integer of 5.

<Preparation of Comparative Examples 1 to 4>

In the compositions and contents shown in Table 1 below, the same method as in Examples 1 to 4 was used, except that no quaternary ammonium cation surfactant was used or a cationic surfactant or cetyltrimethylammonium chloride of Formula 6 was used. To prepare a test shampoo composition of Comparative Examples 1 to 4.

In Chemical Formula 6, R is C ₁₂ H ₂₅ .

Raw material name (% by weight) Example Comparative example One 2 3 4 One 2 3 4 Zinc pyrithione 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.3 Polyquaterny 윰 -10 0.5 0.5 - - 0.5 - 0.5 - Guar hydroxypropyltrimonium chloride - - 0.3 0.3 - 0.3 - 0.3 Quaternary Ammonium Cationic Surfactants of Formula 6 - - - - - - 1.0 - Cetyltrimethylammonium chloride - - - - - - - 1.0 Quaternary Ammonium Cationic Surfactants of Formula 2 1.0 - - - - - - - Quaternary Ammonium Cationic Surfactants of Formula 3 - 1.0 - - - - - - Quaternary Ammonium Cationic Surfactants of Formula 4 - - 1.0 - - - - - Quaternary Ammonium Cationic Surfactants of Formula 5 - - - 1.0 - - - - Sodium Lauryl Sulfate (30%) 20.0 20.0 20.0 20.0 20.0 20.0 20.0 20.0 Sodium polyoxyethylene lauryl sulfate (30%) 30.0 30.0 30.0 30.0 30.0 30.0 30.0 30.0 Palm oil fatty acid diethanolamide 3.0 3.0 3.0 3.0 3.0 3.0 3.0 3.0 Dimethicone 2.0 2.0 2.0 2.0 2.0 2.0 2.0 2.0 Pearl composition 15.0 15.0 15.0 15.0 15.0 15.0 15.0 15.0 Pigment 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 Paraoxybenzoic acid ester 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.20 Spices 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 Sodium chloride 0.50 0.50 0.50 0.50 0.50 0.50 0.50 0.50 Citric acid 0.02 0.20 0.20 0.20 0.20 0.20 0.20 0.20 water Add appropriate amount to 100% by weight.

<Evaluation of coacervate production amount>

In order to measure the amount of coacervate that enhances hair and scalp adsorption of the anti-dandruff component, the concentration using the actual detergent was determined as 10 wt% of the detergent, and 10 g of the sample was diluted in 90 g of water to measure the amount of coacervate at this concentration. The coacervate produced by centrifugation was centrifuged to discard the supernatant and the precipitated portion was taken to determine the amount of coacervate produced. In some cases, when the coacervate production concentration is 10% or less, since it is easy to be washed off when rinsing using an actual detergent, the present invention is based on 10 wt% of the detergent. The results are shown in Table 2 below.

Example 1 Example 2 Example 3 Example 4 Comparative Example 1 Comparative Example 2 Comparative Example 3 Comparative Example 4 Production amount (mg) 60 52 72 65 30 35 43 38

As shown in Table 2, Examples 1 to 4 and quaternary ammonium cationic surfactant compositions containing 1 wt% of quaternary ammonium cationic surfactants (Formula 2 to 5), respectively, based on the total weight of the detergent composition, are not contained. Coacervates of Comparative Examples 1 to 2 containing glyceryl group-containing quaternary ammonium cation surfactant compositions which are simply substituted with alkyl groups and Comparative Examples 4 containing general quaternary cationic surfactants without glyceryl groups Comparing the amount produced, it can be seen that according to the present invention, the compositions of Examples 1 to 4 each containing quaternary ammonium cation surfactants of Formulas 2 to 5 formed more coacervates than Comparative Examples 1 to 4.

In addition, the use of guar hydroxypropyltrimonium chloride as the cationic polymer formed a greater amount of coacervate than the case of using polyquaternib-10, which can be understood as a shape exhibiting relatively strong cationic properties. Comparing Examples 1 to 4 using the quaternary ammonium cationic surfactant according to the present invention, Example 3 using the quaternary ammonium cationic surfactant of Formula 4 having a relatively high molecular weight formed the largest amount of coacervate, and It was confirmed that Example 2 using the quaternary ammonium cation surfactant of formula (3) having a low molecular weight produced the smallest amount of coacervate. This is because coacervates formed by anionic surfactants and cationic polymers are electrically neutralized and exhibit similar behavior to hydrophobic oils. It is judged that a relatively larger amount is incorporated into coacervate phase.

<Measuring Decrease Rate>

160 men and women with relatively high dandruff were selected and 20 people each were used to use the shampoos of Examples 1 to 4 and Comparative Examples 1 to 4 for 1 month. Before the start of the test, the weight of the collected dandruff was collected by using a conventional shampoo and accumulated dandruff for three days, and the weight of the dandruff accumulated every three days with the shampoo of the example or comparative example, and accumulated on the three days after the end of the test. Evaluated. At this time, the collection of accumulated dandruff is to have the experienced tester wash the scalp of the test subjects using about 5 g of the sample, and then rinse with about 2 to 3 liters of water, and then wash the washed water with an 800 micro pore filter medium. The dry weight of the dandruff on the filter medium was measured, and the dandruff reduction rate was calculated by Equation 1, and the results are shown in Table 3.

Example 1 Example 2 Example 3 Example 4 Comparative Example 1 Comparative Example 2 Comparative Example 3 Comparative Example 4 Dandruff reduction rate (%) 36.3 35.2 43.8 39.6 17.9 18.7 23.8 21.0

As shown in Table 3, comparing the results of Examples 1 to 4 and Comparative Examples 1 to 4 containing 1% by weight of the quaternary ammonium cation surfactant of Formulas 2 to 5, respectively, based on the total weight of the detergent composition, It can be seen that the compositions of Examples 1 to 4 containing quaternary ammonium cationic surfactants according to the invention exhibit better anti-dandruff rates. It was also confirmed that this result is directly related to the amount of coacervate formed.

<Evaluation of Anti-dandruff and Itching Reduction>

I think there are a lot of dandruff, 160 men and women who feel itching a lot randomly selected to use the shampoo of the example or comparative example 20 people for each product once every two days for 8 weeks, then through the interview to prevent dandruff effect and Itching effect was evaluated according to the following evaluation criteria and the average value is shown in Table 4 below. Each criterion is as follows.

(Dandruff prevention criteria)

Anti dandruff effect is very good: 5

Good anti-dandruff effect: 4

Anti-dandruff effect is normal: 3

Has some anti-dandruff effects: 2

No anti-dandruff effect: 1

(Itching Reduction Effect Criteria)

Itching effect is very good: 5

Itching effect is good: 4

Itching effect is moderate: 3

Itching effect is slightly reduced: 2

No itching effect at all: 1

Example 1 Example 2 Example 3 Example 4 Comparative Example 1 Comparative Example 2 Comparative Example 3 Comparative Example 4 Anti-dandruff effect (5-point scale) 3.8 3.8 4.3 3.9 3.0 3.1 3.3 3.3 Anti-itch (5-point scale) 3.8 3.6 4.1 4.0 2.8 3.0 3.2 3.1

As shown in Table 4, the dandruff of Examples 1 to 4 and Comparative Examples 1 to 4 each containing 1% by weight of the quaternary ammonium cationic surfactant of Formulas 2 to 5 according to the present invention based on the total weight of the detergent composition Comparing the anti-itch effect, it can be seen that the composition of Examples 1 to 4 containing the quaternary ammonium cationic surfactant according to the present invention shows a better dandruff and anti-itch effect. This was found to be similar to the anti-dandruff rate measurement results.

As described above, the scalp shampoo composition of the present invention contains a cationic surfactant in the form of a quaternary ammonium having a glyceryl group introduced therein to increase the amount of coacervate, and as a result, the scalp contained in the scalp shampoo composition composition Helps to prevent troubles or treatment of the drug to the hair and scalp can be effectively and continuously exhibit excellent effects such as anti-dandruff, antibacterial, stimulation of scalp, itching.

Claims (5)

In the scalp shampoo composition comprising an anionic surfactant and a cationic polymer, Scalp trouble prevention or treatment; And a quaternary ammonium cationic surfactant represented by Formula 1 below: <Formula 1>

In Formula 1, R is any one selected from the group consisting of a linear alkyl group having 12 to 22 carbon atoms, branched alkyl group, alkenyl group and alkylamide, n is an integer of 0 to 10, X is a halogen group element, sulfate Any one selected from the group consisting of a group and an acetate group. The method of claim 1, The content of the quaternary ammonium cationic surfactant is a shampoo composition for scalp, characterized in that 0.1 to 10% by weight relative to the total weight of the composition. The method of claim 1, The scalp trouble prevention or treatment agent is selected from the group consisting of zinc pyrithione, selenium sulfide, pyroxtonolamine, klimbazole, tar, sulfur, salicylic acid, oil-soluble licorice, plant extract oil, mineral extract oil, and derivatives thereof. Shampoo composition for scalp, characterized in that any one or more selected. The method of claim 1, The content of the scalp trouble prevention or treatment agent is a shampoo composition for scalp, characterized in that 0.001 to 5% by weight relative to the total weight of the composition. The method of claim 1, Content of the cationic polymer is a shampoo composition for scalp, characterized in that 0.01 to 5% by weight relative to the total weight of the composition.