KR20060036564A - Body cleanser composition comprising herbal extracts - Google Patents
Body cleanser composition comprising herbal extracts Download PDFInfo
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- KR20060036564A KR20060036564A KR1020040085562A KR20040085562A KR20060036564A KR 20060036564 A KR20060036564 A KR 20060036564A KR 1020040085562 A KR1020040085562 A KR 1020040085562A KR 20040085562 A KR20040085562 A KR 20040085562A KR 20060036564 A KR20060036564 A KR 20060036564A
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- body cleanser
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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Abstract
본 발명은 고삼, 당귀, 석류, 어성초, 우방자, 자몽종자, 황금 추출물 및 천연 올리브 액상 비누를 함유하는 바디클렌저 조성물을 제공한다.The present invention provides a body cleanser composition containing red ginseng, Angelica, pomegranate, eochocho, alligator, grapefruit seed, golden extract and natural olive liquid soap.
본 발명의 바디클렌저 조성물은 조성물 총 중량에 대하여 고삼 추출물 0.01~3.00중량부, 당귀 추출물 0.01~3.00중량부, 석류 추출물 0.01~0.5중량부, 어성초 추출물 0.01~3.00중량부, 우방자 추출물 0.01~3.00중량부, 황금 추출물 0.01~3.00중량부, 자몽 종자 추출물 0.01~2.00중량부 및 천연 올리브 액상비누 0.001~5.00 중량부를 함유한다.The body cleanser composition of the present invention is 0.01-3.00 parts by weight of ginseng extract, 0.01-3.00 parts by weight of Angelica extract, 0.01-3.00 parts by weight of pomegranate extract, 0.01-3.00 parts by weight of pomegranate extract, 0.01-3.00 parts by weight of eojacho extract, 0.01-3.00 weight of allium extract It contains 0.01 to 3.00 parts by weight of golden extract, 0.01 to 2.00 parts by weight of grapefruit seed extract and 0.001 to 5.00 parts by weight of natural olive liquid soap.
본 발명의 바디클렌저 조성물은 생약 추출물과 천연 비누를 함유하여, 바디클렌저가 요구하는 세정, 항균, 피부보습 효과를 나타낼 수 있고, 화학 성분 대신 천연 성분을 함유함으로써 피부 자극을 감소시켜, 피부친화적인 바디클렌저로 사용될 수 있다.The body cleanser composition of the present invention contains a herbal extract and natural soap, and can exhibit the cleansing, antibacterial and skin moisturizing effects required by the body cleanser, and by reducing the skin irritation by containing natural ingredients instead of chemical ingredients, Can be used as a body cleanser.
Description
도 1은 스타필로코커스 아우레우스 균에 대한 각 생약 추출물의 항균활성을 관찰한 사진이다.Figure 1 is a photograph of the antimicrobial activity of each herbal extract against Staphylococcus aureus bacteria.
본 발명은 생약 추출물을 함유하는 바디클렌저 조성물에 관한 것이다.The present invention relates to a body cleanser composition containing a herbal extract.
바디클렌저는 피부표면의 노폐물을 깨끗이 제거하여 청결하고 건강하게 유지시켜주는 세정제로, 사용시 적은 양으로도 기포 발생 정도와 양이 우수하면서 사용시 표면 감촉이 매끄럽고, 피지제거능 및 보습력이 뛰어나며, 물성의 안정성이 우수하고 저자극성인 것이 바람직하다. 특히 인체에 서식하고 있는 Staphylococcus, Streptococcus, Lactobacillus, Escherichia 등과 같은 다양한 세균에 의한 피부감염을 억제할 수 있는 항균작용을 갖는 것이 좋다.Body cleanser is a cleanser that cleans and removes wastes from the surface of the skin and keeps it clean and healthy.It has a high degree of bubble generation and a small amount when using it, and it has a smooth surface feel when using it, and it has excellent sebum removal and moisturizing power, and stability of physical properties. It is preferred that this is excellent and hypoallergenic. In particular , it is good to have an antimicrobial effect that can inhibit skin infection caused by various bacteria such as Staphylococcus, Streptococcus, Lactobacillus, Escherichia inhabiting the human body.
일반적으로 사람의 피부의 염증은 모공 내의 피지에 세균이 침투하거나, 알레르기성 인자에 의해 발생되게 되는데, 바디클렌저를 사용하여 세정할 때, 그 함유 성분에 따라 피부 피지제거 및 살균 효과를 얻음으로써 피부 상태가 개선되도록 한다. In general, inflammation of human skin is caused by bacteria in the sebum in the pores, or caused by allergic factors. When washing with a body cleanser, skin sebum removal and sterilization effects are obtained depending on the ingredients contained therein. Allow the condition to improve.
특히 바디클렌저에서 피지를 제거하는 역할인 계면활성제는 바디클렌저의 주요 성분으로, 화학 합성 물질인 암모늄 라우릴 설페이트 같은 음이온 계면활성제가 많이 사용되고, 또한 세균 감염 방지용 살균제도 화학물질인 합성 항생제, 트리클로산, 트리클로카아반, 파라클로메타크실렌, 디클로로펜, 클로로헥시딘염, 살리실산 등을 사용하나, 피부가 화학 합성 물질에 민감하거나 사용양이 과다하면 오히려 피부와의 직접적인 접촉에 의해 손상을 가져올 수 있다.In particular, the surfactant that removes sebum from the body cleanser is a main component of the body cleanser, and an anionic surfactant such as ammonium lauryl sulfate, which is a chemical synthetic material, is widely used, and a bactericide for preventing bacterial infection is a synthetic antibiotic, triclosan, Triclocaban, paraclomethaxylene, dichlorophene, chlorohexidine salt, salicylic acid, etc. are used, but if the skin is sensitive to chemical synthetic substances or used in excess, it may cause damage by direct contact with the skin.
그래서, 합성물질을 피부에 무해한 천연물질로 대체하기 위해 한약재를 이용한 제품 연구가 예전부터 꾸준히 되어 왔으며, 최근 웰빙산업의 붐과 함께 산업에 본격적으로 이용·부각되고 있다. Therefore, researches on products using herbal medicines have been steadily used to replace synthetic materials with natural substances that are harmless to the skin. Recently, with the boom of the well-being industry, it is being used and highlighted in the industry in earnest.
한편, 고삼(苦蔘, Sophorae Radix)은 콩과에 속하는 다년생초본인 도둑놈의 지팡이(Sophora angustifolia S. et. Z) 뿌리의 코르크층을 제거하여 건조시킨 것으로서(김창민 외, 중약대사전, 1권, pp340-347, 1997, 도서출판 정담, 서울), 예로부터 고미건위약으로 적리, 장출혈, 치질 등에 사용되어 왔다. 또한, 상기 고삼으로부터 다양한 종류의 알칼로이드, 프레닐플라보노이드, 트리테르펜 등의 성분이 분리되었고, 상기 성분들은 항부정맥 작용, 항궤양 활성, 항천식 활성, 항균작용, 항바이러스 활성, 암세포에 대한 세포독성 등의 작용이 보고되어 있다. Meanwhile, Sophorae Radix was dried by removing the cork layer from the root of the cane, Sophora angustifolia S. et.Z , a perennial herb (Kim Chang-min et al., Volume 1, pp340-347, 1997, Jungdam Publishing Co., Ltd., Seoul), and has been used for placebo, intestinal bleeding, and hemorrhoids as a placebo for a long time. In addition, various kinds of alkaloids, prenylflavonoids, triterpenes, and the like were isolated from the ginseng, and the components were antiarrhythmic, antiulcer activity, anti-asthmatic activity, antibacterial activity, antiviral activity, cytotoxicity against cancer cells. The action of the back is reported.
당귀(當歸, Angelica gigas)는 산형과의 이/삼년생 초본으로, 데커신(decursin), 데커시놀(decursinol), 움벨리페론(umbelliferone) 등의 쿠마린계 화합물 및 정유 등을 함유하고, 보혈, 활혈, 거풍, 진통의 효능이 있고, 빈혈, 산후 복통, 월경통, 관절동통, 타박성 동통 등의 치료에 응용한다. Angelica gigas is a two- and three-year-old herb of the mountain family, and contains coumarin-based compounds such as decursin, decursinol, and umbelliferone and essential oils. It is effective in the treatment of the anemia, postpartum pain, postpartum abdominal pain, dysmenorrhea, arthralgia, and bruise pain.
석류(Punica granatum)는 석류과에 속하는 낙엽소목으로, 예부터 열매와 줄기껍질과 뿌리껍질을 건조하여 사용하였으며, 촌충의 구제, 설사, 이질, 구내염, 장출혈 등에 효과가 있고, 이소펠레티에린(isopelletierine)과 같은 알칼로이드, 푸니칼린(punicalin), 푸니칼라진(punicalagin)과 같은 탄닌류, 이눌린(inuline), 만니톨(mannitol), 소르비톨(sorbitol), 말산(malic acid) 등을 함유한다(심선미 등, 한국식품영양과학회지, vol.30(1), pp80~85, 2001).Pomegranate ( Punica granatum ) is a deciduous tree belonging to the pomegranate family, which has been used since dried fruit, stem bark and root bark. Alkaloids such as), tannics such as punicalin, punicalagin, inuline, mannitol, sorbitol, malic acid, etc. , Journal of the Korean Society of Food Science and Nutrition, vol. 30 (1), pp80 ~ 85, 2001).
어성초(魚腥草; Houttuynia cordata)는 삼백초과에 속하는 다년생 초본으로, 흔히 '약모밀'이라고 불리우며, 플라보노이드, 휘발성 정유성분, 비타민 등을 함유하고 있다. 청열(淸熱)), 해독(解毒), 이뇨(利尿), 소염·항염 효과, 살균·항균 효과가 있고, 피부미용에 좋은 효과를 나타내는 것으로 알려져 있다.Eoseongcho (魚腥草; Houttuynia cordata ) is a perennial herb belonging to more than three hundred, commonly called 'weak wheat', and contains flavonoids, volatile essential oils and vitamins. Clear heat, detoxification, diuresis, anti-inflammatory and anti-inflammatory effects, bactericidal and antibacterial effects, and are known to have good effects on skin beauty.
우방자(牛蒡子, Arctii Fructus)는 우엉(Arctium lappa Linne)의 종자로서, 악틴(arctin), 라파올 A, B, C, D, E(lappaol A, B, C, D, E), 악티게닌(arctigenin), 아락티딕 산(aractidic acid) 등을 함유하며, 해독(解毒)·소염(消炎)·배농(排膿)의 효과가 있으며, 화농성(化膿性) 종기, 피부병 등에 쓰이는 경우가 많고, 감기, 인후통, 편도선염 등의 치료에도 응용한다. Arctii Fructus is a seed of the burdock (Arcium lappa Linne), actin, rapaol A, B, C, D, E (lappaol A, B, C, D, E), actinigen (arctigenin) and arcactidic acid, etc., and detoxification, anti-inflammatory, drainage effect, and often used for purulent boils, skin diseases, etc. It is also applied to the treatment of colds, sore throat and tonsillitis.
황금(黃芩, Scutellariae Radix)은 꿀풀과에 속하는 황금(Scutellaria baicallensis Georgi)의 근으로, 바이칼린(Baicalin), 바이칼레인(Baicalein), 우고닌(Woogonin), 우고노시드(Wogonoside), 네오바이칼레인(Neobaicalein), β-시토스테롤(β-Sitosterol) 등을 함유하고 있으며, 해열, 소염, 이뇨, 건위 정장(健胃 整腸), 위액분비억제, 항균작용이 있어, 소염제, 해열제, 진통, 지사, 이담제로 응용되고 있다.Scutellariae Radix is the root of Scutellaria baicallensis Georgi, which belongs to the Lamiaceae family. (Neobaicalein), β-Sitosterol (β-Sitosterol), etc., antipyretic, anti-inflammatory, diuretic, dry stomach, gastric juice secretion, antibacterial, anti-inflammatory, antipyretic, analgesic, branch, It is applied as a bottling agent.
한국 특허출원 제10-2002-73626호에는 항균 및 미용기능을 갖는 감초, 고삼, 백반, 사간, 오배자, 죽순, 천궁, 황금, 황련 또는 황백 추출물과 이를 함유한 제품이 공지되어 있고, 한국 특허출원 제10-2001-5584호에는 의이인, 우방자, 대추, 감초, 어성초, 지각, 황금, 산사, 당귀, 황연, 황백, 청피, 상황 추출물을 함유하는 여드름 균 생장억제용 미용용품 첨가제 조성물이 공지되어 있다.Korean Patent Application No. 10-2002-73626 discloses licorice, red ginseng, white spot, liver, gall, bamboo shoot, cheonggung, golden, yellow lotus or yellow white extract with antibacterial and cosmetic functions and products containing the same. No. 10-2001-5584 discloses a cosmetics additive composition for inhibiting acne bacteria growth, containing Euiin, allies, jujube, licorice, erukcho, crust, golden, hawthorn, Angelica, yellow lead, yellow white, blue skin, and situation extract. .
이에 본 발명자는 피부친화적인 바디클렌저를 제조하기 위해 지속적으로 연구하여, 기존의 항균제, 보습제로 사용되는 화학 약제를 대신할 수 있는, 피부친화적인 생약 추출물을 첨가하여 저자극적이고 피부에 안전성이 우수한 바디클렌저를 개발함으로써 본 발명을 완성하였다.Therefore, the present inventors continue to study to prepare a skin-friendly body cleanser, it is hypoallergenic and excellent in safety to the skin by adding a skin-friendly herbal extract, which can replace the conventional antimicrobial agent, a chemical agent used as a moisturizer The present invention has been completed by developing a body cleanser.
본 발명에서는 고삼, 당귀, 석류, 어성초, 우방자, 황금 추출물, 자몽종자 추출물 및 천연 올리브 액상비누를 함유하여, 화학물질의 사용을 줄이고, 항균 효과가 우수하며, 저자극적인 바디클렌저 조성물을 제공하고자 한다.The present invention contains red ginseng, Angelica, pomegranate, eochocho, allium, golden extract, grapefruit seed extract and natural olive liquid soap, to reduce the use of chemicals, to provide an excellent antibacterial effect, hypoallergenic body cleanser composition .
본 발명은 고삼, 당귀, 석류, 어성초, 우방자, 자몽종자, 황금 추출물 및 천연 올리브 액상 비누를 함유하는 바디클렌저 조성물을 제공한다.The present invention provides a body cleanser composition containing red ginseng, Angelica, pomegranate, eochocho, alligator, grapefruit seed, golden extract and natural olive liquid soap.
본 발명의 바디클렌저 조성물은 조성물 총 중량에 대하여 고삼 추출물 0.01~3.00중량부, 당귀 추출물 0.01~3.00중량부, 석류 추출물 0.01~0.5중량부, 어 성초 추출물 0.01~3.00중량부, 우방자 추출물 0.01~3.00중량부, 황금 추출물 0.01~3.00중량부, 자몽 종자 추출물 0.01~2.00중량부 및 천연 올리브 액상비누 0.001~10.00 중량부, 계면활성제 10~25중량부, 용제 50~95 중량부를 함유한 것이 바람직하며, 생약 추출물 혼합물은 조성물 총 중량에 대하여 1.00~7.00중량부인 것이 바람직하다.The body cleanser composition of the present invention is 0.01-3.00 parts by weight of ginseng extract, 0.01-3.00 parts by weight of Angelica extract, 0.01-0.5 parts by weight of pomegranate extract, 0.01-3.00 parts by weight of fish vinegar extract, 0.01-3.00 parts by weight of allium extract. It is preferable to contain a weight part, 0.01-3.00 weight part of golden extracts, 0.01-2.00 weight part of grapefruit seed extracts, and 0.001-10.00 weight part of natural olive liquid soaps, 10-25 weight part of surfactants, and 50-95 weight part of solvents, The herbal extract mixture is preferably 1.00-7.00 parts by weight based on the total weight of the composition.
또한, 본 발명의 조성물에서 고삼, 당귀, 석류, 어성초, 우방자, 황금, 자몽종자 추출물 및 천연 올리브 액상비누의 혼합비는 1~2 : 2 : 1 : 1~2 : 0.1 : 1 : 0.5~1: 5가 될 수 있다. In addition, in the composition of the present invention, the mixing ratio of red ginseng, Angelica, pomegranate, fish vinegar, allium, golden, grapefruit seed extract and natural olive liquid soap is 1-2: 2: 1: 1: 1-2: 0.1: 1: 10.5-1: 1. It can be five.
본 발명의 조성물에 사용하는 생약은 통상적인 건조 방법에 따라 생약 자체를 건조시켜 건조물 상태 또는 상기 건조물을 세절 또는 분말 형태로 하여, 통상적인 추출 방법, 예를 들면 열수 추출 또는 유기용매로 추출하여 사용한다. The herbal medicine used in the composition of the present invention may be dried and dried in the form of a dried product or the dried product according to a conventional drying method, or in the form of powder, or a conventional extraction method such as hot water extraction or an organic solvent. do.
본 발명의 조성물에 사용하는 생약 추출물의 구체적인 제조방법은, 건조한 생약을 세절한 후, 생약 무게의 약 2배 내지 20배의 물, C1 내지 C4의 탄소수를 갖는 저급 알콜 또는 이들의 혼합용매, 바람직하게는 물 또는 에탄올을 사용하여, 실온 내지 100 ℃의 추출온도에서 약 2시간 내지 10일 동안 열수추출, 냉침추출, 초음파 추출 또는 환류냉각 추출 등의 추출방법에 의하여 1회 내지 5회 반복하여 추출한 후, 추출물을 여과, 감압농축 또는 동결건조하여 제조된다. Specific method for producing a herbal extract used in the composition of the present invention, after cutting the dry herbal medicine, water of about 2 to 20 times the weight of the herbal medicine, lower alcohol having a carbon number of C1 to C4 or a mixed solvent thereof, preferably Preferably, using water or ethanol, extracted repeatedly from 1 to 5 times by extraction methods such as hot water extraction, cold extraction, ultrasonic extraction or reflux cooling extraction for about 2 hours to 10 days at an extraction temperature of room temperature to 100 ℃ The extract is then prepared by filtration, concentrated under reduced pressure or lyophilized.
상기 용매는 생약 무게의 3배 이상을 사용하는 것이 바람직한 추출효과를 나타내며, 20배 이상을 사용할 때는 용매가 추출량에 비하여 많이 소요되는 경향이 있다. The solvent exhibits a preferable extraction effect to use at least three times the weight of the herbal medicine, when using more than 20 times the solvent tends to take a lot compared to the extraction amount.
본 발명의 자몽종자추출물은 직접 상기와 같은 방법으로 제조할 수도 있고, 시판하는 것을 사용할 수 있다.Grapefruit seed extract of the present invention may be prepared by the same method as described above, or may be commercially available.
본 발명의 바디클렌저에 사용된 천연 올리브 액상 비누는 핸드메이드 비누로서, 올리브오일, 코코넛오일, 팜오일, 어성초 엑기스를 비누화한 고형비누를 30일간 숙성한 뒤 액화처리하여 제조될 수 있다. Natural olive liquid soap used in the body cleanser of the present invention is a handmade soap, olive oil, coconut oil, palm oil, can be prepared by liquefying the solid soap soap saponified extract 30 days.
본 발명의 조성물에 함유되는 계면활성제는 음이온 계면활성제, 양이온 계면활성제, 비이온성 계면활성제, 양쪽성계면활성제를 포함한다.Surfactants contained in the composition of the present invention include anionic surfactants, cationic surfactants, nonionic surfactants, and amphoteric surfactants.
계면활성제 중 음이온 계면활성제는 구체적으로 암모늄 라우릴술포숙시네이트, 암모늄 라우릴 설페이트, 소디움 코코일 이세시오네이트, 소디움 라우릴 이세시오네이트, 소디움 라우릴 설페이트, 트리에탄올아민 라우릴 설페이트, 소디움 라우릴 에테르 설페이트(에틸렌옥사이드 1-3개) 등이 될 수 있다.Anionic surfactants among the surfactants are specifically ammonium laurylsulfosuccinate, ammonium lauryl sulfate, sodium cocoyl isionate, sodium lauryl isceionate, sodium lauryl sulfate, triethanolamine lauryl sulfate, sodium lauryl Ether sulfate (1-3 ethylene oxide) and the like.
계면활성제 중 비이온성 계면활성제는 구체적으로 폴리옥시에틸렌알킬에테르, 폴리옥시에틸렌지방산 에스테르, 폴리옥시에틸렌, 폴리소르베이트 80, 경화 피마자유 유도체, 지방산 디에탄올아미드, 글리세릴스테아레이트 등이 될 수 있다.Among the surfactants, the nonionic surfactant may specifically be polyoxyethylene alkyl ether, polyoxyethylene fatty acid ester, polyoxyethylene, polysorbate 80, hardened castor oil derivative, fatty acid diethanolamide, glyceryl stearate, or the like. .
계면활성제 중 양이온성 계면활성제는 구체적으로 3급 지방족 아민염, 알킬트리메칠암모늄클로라이드, 디알킬디메칠암모늄클로라이드 등이 될 수 있다.The cationic surfactant in the surfactant may specifically be a tertiary aliphatic amine salt, alkyltrimethylammonium chloride, dialkyldimethylammonium chloride, or the like.
계면활성제 중 양쪽성 계면활성제는 구체적으로 베타인, 아미드베타인형, 설포베타인형, 스테아르트리모늄클로라이드 등이 될 수 있다.Among the surfactants, the amphoteric surfactant may be specifically betaine, amidebetaine type, sulfobetaine type, steartrimonium chloride, or the like.
pH 조정제는 구체적으로 시트르산, 숙신산, 타르타르산, 락트산, 말산, 푸마르산, 말레산, 글리콜산 등의 유기산, 염산, 황산, 인산, 질산 등의 무기산 중 어 느 것이라도 사용할 수 있으며, 이들 산의 나트륨염, 칼륨염 또는 암모늄염 등을 조합하여 사용할 수 있으며, 트리에탄올아민, 소듐클로라이드, 수산화나트륨, 수산화칼륨 등을 사용할 수도 있다. Specifically, the pH adjusting agent can be used any of organic acids such as citric acid, succinic acid, tartaric acid, lactic acid, malic acid, fumaric acid, maleic acid and glycolic acid, and inorganic acids such as hydrochloric acid, sulfuric acid, phosphoric acid and nitric acid, and sodium salts of these acids. , Potassium salts or ammonium salts and the like can be used in combination, and triethanolamine, sodium chloride, sodium hydroxide, potassium hydroxide and the like can also be used.
보습제는 구체적으로 에틸렌글리콜, 디에틸렌글리콜, 트리에틸렌글리콜, 폴리에틸렌글리콜, 프로필렌글리콜, 디프로필렌글리콜, 1,3-부틸렌글리콜, 글리세린, 솔비톨, 콜라겐 등 기존에 사용되어 온 보습성분 중에서 1종 또는 2종 이상을 혼합하여 사용할 수 있으며, 조성물 총 중량에 대하여 0.1~10 중량부를 함유한다. Specifically, the moisturizing agent may include one or more of moisturizing ingredients previously used such as ethylene glycol, diethylene glycol, triethylene glycol, polyethylene glycol, propylene glycol, dipropylene glycol, 1,3-butylene glycol, glycerin, sorbitol, and collagen. It can mix and use 2 or more types, and contains 0.1-10 weight part with respect to the total weight of a composition.
방부제는 구체적으로 벤조산, 파라옥시안식향산에스테르, 메칠클로로이소치아졸리논의 혼합물, 페녹시에탄올, 디엠디엠 히단토인, 메틸 파라벤(Methyl paraben), 에틸파라벤, 프로필파라벤 등이 될 수 있다.The preservative may specifically be benzoic acid, paraoxybenzoic acid ester, mixture of methylchloroisothiazolinone, phenoxyethanol, DMH hydantoin, methyl paraben, ethyl paraben, propylparaben and the like.
용제는 구체적으로 정제수, 에탄올, 트윈 20, 사이클로메치콘, 미네랄오일, 디메치콘 등이 될 수 있다.The solvent may be specifically purified water, ethanol, Tween 20, cyclomethicone, mineral oil, dimethicone and the like.
착향제 및 색소는 일반적인 피부 세정제에 사용되는 성분들을 사용할 수 있다.Flavoring agents and pigments may use ingredients used in common skin cleansers.
또한, 본 발명의 바디클렌저 조성물은 액상, 고형의 비누, 분말로 제형화할 수 있다.In addition, the body cleanser composition of the present invention can be formulated as a liquid, solid soap, powder.
본 발명의 바디클렌저 조성물이 함유한 고삼, 황금 추출물은 그람 양성균에 대하여 항균활성을 나타내고, 자몽종자 추출물은 그람 양성 및 음성균에 대하여 항균활성을 나타내며, 당귀, 석류, 우방자, 어성초 추출물은 피부보습 등 피부상태 개선 효과를 나타낸다. 또한, 천연 올리브 액상 비누를 함유하는 본 발명의 조성물 은 화학 계면활성제 사용량을 줄이고 천연물질로서 대체하여 환경에 친화적이고, 화학적 성분에 의한 피부 손상을 막을 수 있으며, 필수지방산, 비타민 E, 알파 리놀렌산, 폴리페놀류 등의 인체 유효성분을 다량 함유하여 피부노화방지 효과가 있다.The ginseng and golden extracts contained in the body cleanser composition of the present invention exhibit antimicrobial activity against gram-positive bacteria, grapefruit seed extracts exhibit antimicrobial activity against gram-positive and negative bacteria, and the extracts of Angelica sinensis, pomegranate, allium and estuary are moisturized, etc. It has an effect of improving skin condition. In addition, the composition of the present invention containing a natural olive liquid soap is reduced to the amount of chemical surfactants and replaced with natural substances, environmentally friendly, can prevent skin damage by chemical components, essential fatty acids, vitamin E, alpha linolenic acid, It contains a large amount of active ingredients, such as polyphenols, to prevent skin aging.
이와 같이 본 발명의 바디 클렌저 조성물은 천연 생약 추출물을 함유함으로써 바디클렌저의 필요조건인 세정, 항균, 피부보습 효과를 나타낼 뿐 아니라 피부 자극을 최소화할 수 있다.As such, the body cleanser composition of the present invention may not only exhibit clean, antibacterial and moisturizing effects of the body cleanser, but also minimize skin irritation.
이하, 본 발명의 이해를 돕기 위하여 바람직한 실시예를 제시한다. 그러나 하기의 실시예는 본 발명을 보다 쉽게 이해하기 위하여 제공되는 것일 뿐, 실시예에 의해 본 발명의 내용이 한정되는 것은 아니다.Hereinafter, preferred examples are provided to aid in understanding the present invention. However, the following examples are merely provided to more easily understand the present invention, and the contents of the present invention are not limited by the examples.
[실시예] 본 발명의 바디클렌저 조성물의 제조EXAMPLES Preparation of the Body Cleanser Composition of the Present Invention
1-1) 본 발명의 조성물이 함유하는 생약 추출물 제조예 11-1) Preparation Example 1 of the herbal extract contained in the composition of the present invention
본 발명의 조성물을 제조하기 위해, 고삼(뿌리), 당귀(뿌리), 어성초(전초), 우방자(우엉의 종자), 석류(열매), 황금(뿌리) 추출물을 하기와 같이 제조하였다. In order to prepare the composition of the present invention, red ginseng (root), Angelica (root), eoseongcho (outpost), milkweed (seed of burdock), pomegranate (fruit), golden (root) extract was prepared as follows.
상기 각 건조생약을 100% 에탄올과 1:3(w/w)으로 혼합한 후, 실온에서 저속교반하면서 72시간 동안 추출하였다. 추출물을 유리섬유(GF/C, pore size 1.0㎛ ) 필터를 사용하여 진공 필터한 뒤, 여과된 추출물을 본 발명의 바디클렌저 조성물 제조에 사용하였다.Each dry herbal mixture was mixed with 100% ethanol at 1: 3 (w / w), and then extracted for 72 hours while stirring at room temperature at low speed. The extract was vacuum filtered using a glass fiber (GF / C, pore size 1.0 μm) filter, and the filtered extract was used to prepare the body cleanser composition of the present invention.
1-2) 본 발명의 조성물이 함유하는 생약 추출물 제조예 21-2) Herbal Medicine Extract Preparation Example 2 Contained in the Composition of the Present Invention
상기 각 건조생약을 증류수와 1:10(w/w)으로 혼합한 후, 약탕기를 이용하여 약 80~90 ℃에서 2시간동안 가열하였다. 추출물을 GF/C 필터를 사용하여 진공 필터하고 여과된 추출물을 본 발명의 바디클렌저 조성물 제조에 사용하였다. Each dry herb was mixed with distilled water at 1:10 (w / w), and then heated at about 80-90 ° C. for 2 hours using a medicine bath. The extract was vacuum filtered using a GF / C filter and the filtered extract was used to prepare the body cleanser composition of the present invention.
1-3) 각 생약 추출물의 항균 활성도 측정1-3) Antimicrobial Activity of Each Herb Extract
상기에서 제조된 생약 추출물의 항균 활성을 하기와 같이 측정하였다. The antimicrobial activity of the herbal extract prepared above was measured as follows.
자몽종자 추출물은 브라질산 CITRIC EXTRACT 200(PANGERMEX grapefruit seed extract batch 288)을 사용하여 항균활성을 측정하였다.Grapefruit seed extract was measured for antimicrobial activity using Brazilian CITRIC EXTRACT 200 (PANGERMEX grapefruit seed extract batch 288).
항균력은 바실러스 서브틸리스(Bacillus subtilis), 스타필로코터스 아우레우스(Staphylococcus aureus), 세라티아종(Serratia sp.), 대장균(E.coli), 살모넬라 종(Sallmonella sp.), 쉬겔라 종(Shigella sp.), 스트렙토마이세스 뮤리우스(Streptomyces murius), 아스퍼질러스 니거(Aspergillus niger), 총 8가지 균주를 사용하였다.Antibacterial activity is Bacillus subtilis , Staphylococcus aureus , Serratia sp., E. coli , Salmonella sp., Shigella sp. ( Shigella sp.), Streptomyces Streptomyces murius , Aspergillus niger , A total of eight strains were used.
상기 균들을 액체배지에 배양한 후, 균수를 측정하여 같은 양으로 PCA(Plate Count Agar) 고체배지에 도말하여 접종한 후, 37 ℃의 혐기상태에서 48시간 배양하였다. 각각의 균이 접종된 플레이트에 지름 1cm 정도의 구멍을 만들고, 여기에 상기 1-1)의 방법에 의해 수득된 고삼, 황금, 당귀, 우방자 추출물 및 자몽 종자 추출물을 증류수에 0.5 %, 1 %로 희석하여 100 ㎕의 양으로 떨어뜨린 후, 24시간(세균) 또는 48시간(곰팡이)을 더 배양하여 생긴 투명환(clear zone)의 지름을 측정하여, 항균 활성도를 측정하였다. After incubating the bacteria in a liquid medium, the number of bacteria was measured and plated on the same amount of plate count agar (PCA) solid medium and inoculated, and then incubated for 48 hours at 37 ℃ anaerobic. A hole about 1 cm in diameter was made in each inoculated plate, and the red ginseng, golden, donkey, allium extract and grapefruit seed extract obtained by the method of 1-1) were added to distilled water at 0.5% and 1%. After diluting and dropping to an amount of 100 μl, the diameter of the clear zone generated by further culturing for 24 hours (bacteria) or 48 hours (fungus) was measured to measure the antibacterial activity.
실험결과는 표 1에 나타내었다.The experimental results are shown in Table 1.
투명환은 균 및 곰팡이의 생장이 저해된 부분으로, 투명환(저해환)의 지름크기를 통해 추출물에 의한 항균 및 항곰팡이 활성을 판단할 수 있다Transparent ring is a part which inhibited the growth of fungi and molds, and can determine the antibacterial and antifungal activity by the extract through the diameter of the transparent ring (inhibitory ring).
상기 표 1을 보면 고삼 및 황금 추출물은 그람 양성인 바실러스 서브틸리스, 스타필로코커스 아우레스, 스트렙토마이세스 무리우스에 항균효과를 나타내고, 당귀 추출물도 바실러스 서브틸리스 및 스트렙토 마이세스 무리우스에 약간의 항균활성을 나타냄을 확인할 수 있고, 희석농도가 증가함에 따라 그 항균활성도 증가하였다.Table 1 shows that the ginseng and golden extracts exhibit antimicrobial effects on Gram-positive Bacillus subtilis, Staphylococcus aureus, Streptomyces Murius, and the Angelica extract also slightly to Bacillus subtilis and Streptomyces Murius. It can be seen that it shows antimicrobial activity, and as the dilution concentration increased, the antimicrobial activity also increased.
자몽종자 추출물의 경우 그람 양성 및 그람 음성 균에 대해 강한 항균활성을 나타내었다.Grapefruit seed extract showed strong antimicrobial activity against gram positive and gram negative bacteria.
그리고, 고삼, 황금, 자몽종자 추출물에서 곰팡이인 아스퍼질러스 니거에 대해 항곰팡이 활성을 나타내었다.In addition, the extract showed antifungal activity against Aspergillus niger, a fungus, from the extracts of red ginseng, gold and grapefruit seeds.
도 1은 스타필로코커스 아우레우스 균에 대한 각 생약 추출물의 항균활성을 관찰한 사진이다.Figure 1 is a photograph of the antimicrobial activity of each herbal extract against Staphylococcus aureus bacteria.
표 1의 결과를 보면, 생약 추출물은 그람음성균에 대한 효과는 약하나, 그람양성균에 대한 효과는 농도에 비례하여 억제 효과가 뛰어났다. 그러나 자몽추출물은 그람양성균과 그람음성균 모두 저해효과가 뛰어나며, 곰팡이인 Aspergillus niger에도 또한 뛰어났다.In the results of Table 1, the herbal extracts were weak against Gram-negative bacteria, but the effects on Gram-positive bacteria were excellent in inhibitory proportions. However, grapefruit extracts were also effective against both Gram-positive and Gram-negative bacteria, as well as the fungus Aspergillus niger .
1-4) 본 발명의 바디클렌저 조성물의 제조1-4) Preparation of Body Cleanser Composition of the Present Invention
본 발명의 바디클렌저 조성물 및 비교예 조성물을 하기 표 2의 성분 및 함량으로 혼합하여 제조하였다.The body cleanser composition and the comparative example composition of the present invention were prepared by mixing the components and contents of Table 2 below.
[시험예 1] 생약 추출물 혼합물을 함유한 바디클렌저 조성물의 항균 활성도 측정[Test Example 1] Antibacterial activity of the body cleanser composition containing the herbal extract mixture
본 발명의 바디클렌저 조성물의 항균효과를 다음과 같이 측정하였다.Antibacterial effect of the body cleanser composition of the present invention was measured as follows.
상기 표 2의 실시예 3 조성에 따라 제조한 바디클렌저 조성물을 이용하였고, 이때 함유하는 추출물을 하기 표 3의 조성에 따라 상기 실시예 1-1) 생약 추출물 및 1-2) 생약추출물을 첨가하여 제조하였다. 이 조성물을 증류수에 0.5%, 1.0%, 10.0% 의 농도별로 희석하여 항균, 항곰팡이 활성을 상기 1-3)에서와 같은 방법으로 시험하였다.The body cleanser composition prepared according to the composition of Example 3 of Table 2 was used, and the extract containing the above Example 1-1) herbal extract and 1-2) herbal extracts were added according to the composition of Table 3 below. Prepared. The composition was diluted in distilled water at concentrations of 0.5%, 1.0% and 10.0% to test the antimicrobial and antifungal activity in the same manner as in 1-3).
결과는 표 4에 나타내었다. The results are shown in Table 4.
표 4의 결과를 보면, 본 발명의 바디클렌저 조성물은 희석농도 1 % 내지 10 % 일 때, 각각의 균주에 대해 생장을 억제하여 항균효과를 나타냄을 알 수 있었다.Looking at the results of Table 4, the body cleanser composition of the present invention was found to exhibit an antimicrobial effect by inhibiting growth for each strain when the dilution concentration of 1% to 10%.
[시험예 2] 본 발명의 조성물을 이용한 피부질환 개선 효과 시험[Test Example 2] Skin disease improvement effect test using the composition of the present invention
본 발명의 바디클렌저 조성물의 피부질환 개선 효과 시험을 실시하였다.The skin disease improvement effect test of the body cleanser composition of this invention was done.
시험은 가려움증 등 피부질환이 의심되는 20대에서 30대의 남녀 60명을 대상으로 실시하였다. 상기 실시예 1-6)에서 제조한 7개 조성물에 각각 10명씩 배정하 고, 각 조성물들을 일주일에 걸쳐 하루 1회씩 5 ㎖ 씩을 물 45 ㎖와 혼합하여 목욕용 퍼프에 묻혀 사용하게 하였다. 이후 시험대상자들은 피부질환개선, 피부 저자극성, 가려움증 감소, 피부 보습, 전체적인 사용감에 대하여 평가 기준(표 5 참조)에 따라 평가하였고, 그 결과를 표 6에 나타내었다.The test was conducted on 60 men and women in their 20s and 30s who suspected skin diseases such as itching. Ten people were assigned to each of the seven compositions prepared in Example 1-6), and 5 ml of each composition was mixed with 45 ml of water once a day over a week and buried in a bath puff. The subjects were then evaluated according to the evaluation criteria (see Table 5) for skin disease improvement, skin hypoallergenicity, itching reduction, skin moisturization, and overall feeling of use, and the results are shown in Table 6.
상기의 결과를 보면, 실시예 1, 2, 3 조성물에서 피부질환 개선, 피부저자극성과 같은 피부보호, 가려움증 감소 및 부드러움 등 보습효과가 가장 뛰어남을 확인할 수 있었다. In the above results, it was confirmed that the moisturizing effects such as skin diseases, skin protection, itching reduction and softness, etc. were most excellent in Examples 1, 2, and 3 compositions.
본 발명의 바디클렌저 조성물은 고삼, 당귀, 석류, 어성초, 우방자, 황금 추출물, 자몽종자 추출물, 천연 올리브 액상 비누를 함유함으로써, 바디클렌저의 필요조건인 세정, 항균, 피부보습 효과를 나타낼 뿐만 아니라, 화학 성분 대신 천연 성분을 함유함으로써 피부 자극을 최소화하여, 피부친화적인 바디클렌저로 사용될 수 있다.The body cleanser composition of the present invention by containing red ginseng, Angelica, pomegranate, fish vinegar, allies, golden extract, grapefruit seed extract, natural olive liquid soap, as well as showing the cleansing, antibacterial, skin moisturizing effect of the body cleanser requirements, By containing natural ingredients instead of chemical ingredients, skin irritation can be minimized and used as a skin-friendly body cleanser.
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KR100842169B1 (en) * | 2007-05-10 | 2008-06-27 | 대구보건대학산학협력단 | Preparation method of functional soap containing chajogi and hwanggeum extracts |
KR20150125212A (en) | 2014-04-30 | 2015-11-09 | (주)월드코스텍 | Body cleanser composition comprising lye from eggplant and manufacturing method of the same |
KR102106644B1 (en) | 2018-11-29 | 2020-05-06 | 임정훈 | Body shower for children using natural materials |
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KR100789471B1 (en) | 2006-09-11 | 2008-01-02 | 윤석영 | Soap and method of manufacturing the same |
KR101685686B1 (en) * | 2015-05-29 | 2016-12-12 | 곽민선 | Scrub Cosmetic Composition Comprising Solar Salt |
KR20190095053A (en) | 2018-02-06 | 2019-08-14 | 동강대학교산학협력단 | Body cleanser containing extracts of lycium chnence |
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KR100842169B1 (en) * | 2007-05-10 | 2008-06-27 | 대구보건대학산학협력단 | Preparation method of functional soap containing chajogi and hwanggeum extracts |
KR20150125212A (en) | 2014-04-30 | 2015-11-09 | (주)월드코스텍 | Body cleanser composition comprising lye from eggplant and manufacturing method of the same |
KR102106644B1 (en) | 2018-11-29 | 2020-05-06 | 임정훈 | Body shower for children using natural materials |
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