KR20060006048A - 카나비노이드 수용체 리간드 및 그의 용도 - Google Patents
카나비노이드 수용체 리간드 및 그의 용도 Download PDFInfo
- Publication number
- KR20060006048A KR20060006048A KR1020057020010A KR20057020010A KR20060006048A KR 20060006048 A KR20060006048 A KR 20060006048A KR 1020057020010 A KR1020057020010 A KR 1020057020010A KR 20057020010 A KR20057020010 A KR 20057020010A KR 20060006048 A KR20060006048 A KR 20060006048A
- Authority
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- South Korea
- Prior art keywords
- compound
- alkyl
- pharmaceutically acceptable
- substituted
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- Health & Medical Sciences (AREA)
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- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Rheumatology (AREA)
- Reproductive Health (AREA)
- Hospice & Palliative Care (AREA)
- Emergency Medicine (AREA)
- Psychology (AREA)
- Nutrition Science (AREA)
- Gynecology & Obstetrics (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| KR20200139751A (ko) * | 2018-04-02 | 2020-12-14 | 케모센트릭스, 인크. | 융합된-바이사이클릭 C5aR 길항제의 프로드러그 |
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| US7268133B2 (en) | 2003-04-23 | 2007-09-11 | Pfizer, Inc. Patent Department | Cannabinoid receptor ligands and uses thereof |
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| WO2004099157A1 (en) * | 2003-05-07 | 2004-11-18 | Pfizer Products Inc. | Cannabinoid receptor ligands and uses thereof |
| US7232823B2 (en) * | 2003-06-09 | 2007-06-19 | Pfizer, Inc. | Cannabinoid receptor ligands and uses thereof |
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| CA2544191A1 (en) * | 2003-11-04 | 2005-05-26 | Merck & Co., Inc. | Substituted naphthyridinone derivatives |
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| DE602005026037D1 (de) * | 2004-10-27 | 2011-03-03 | Janssen Pharmaceutica Nv | Tetrahydro pyridinyl pyrazole cannabinoid modulatoren |
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| AR055601A1 (es) * | 2005-08-09 | 2007-08-29 | Glaxo Group Ltd | Compuestos derivados de imidazopiridina como ligandos de receptores canabinoides |
| EP1951678A1 (en) * | 2005-10-21 | 2008-08-06 | Mitsubishi Tanabe Pharma Corporation | Pyrazole compounds having cannabinoid receptor (cb1) antagonizing activity |
| US20090264470A1 (en) * | 2006-02-21 | 2009-10-22 | Bennett Teresa A | CB1 Antagonists and Inverse Agonists |
| BRPI0715160A2 (pt) | 2006-08-08 | 2013-06-11 | Sanofi Aventis | imidazolidina-2,4-dionas substituÍdas por arilamimoaril-alquil-, processo para preparÁ-las, medicamentos compeendendo estes compostos, e seu uso |
| US20080108574A1 (en) * | 2006-09-27 | 2008-05-08 | Braincells, Inc. | Melanocortin receptor mediated modulation of neurogenesis |
| PE20090142A1 (es) * | 2007-04-11 | 2009-02-19 | Merck & Co Inc | Derivados de furo[2,3-b] piridina sustituidos como moduladores del receptor canabinoide-1 |
| EP2025674A1 (de) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| EP2242745A1 (de) * | 2008-02-07 | 2010-10-27 | Sanofi-Aventis | Neue phenyl-substituierte imidazolidine, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
| US8470841B2 (en) | 2008-07-09 | 2013-06-25 | Sanofi | Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof |
| JO2870B1 (en) | 2008-11-13 | 2015-03-15 | ميرك شارب اند دوهم كورب | Amino Tetra Hydro Pirans as Inhibitors of Peptide Dipeptide IV for the Treatment or Prevention of Diabetes |
| WO2010068601A1 (en) | 2008-12-08 | 2010-06-17 | Sanofi-Aventis | A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof |
| ES2443016T3 (es) | 2009-08-26 | 2014-02-17 | Sanofi | Nuevos hidratos cristalinos de fluoroglicósidos heteroaromáticos, productos farmacéuticos que comprenden estos compuestos, y su empleo |
| WO2011037793A1 (en) | 2009-09-25 | 2011-03-31 | Merck Sharp & Dohme Corp. | Substituted aminopiperidines as dipeptidyl peptidase-iv inhibitors for the treatment of diabetes |
| EP2582709B1 (de) | 2010-06-18 | 2018-01-24 | Sanofi | Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen |
| EP2683704B1 (de) | 2011-03-08 | 2014-12-17 | Sanofi | Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| EP2683701B1 (de) | 2011-03-08 | 2014-12-24 | Sanofi | Mit benzyl- oder heteromethylengruppen substituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| US8809325B2 (en) | 2011-03-08 | 2014-08-19 | Sanofi | Benzyl-oxathiazine derivatives substituted with adamantane and noradamantane, medicaments containing said compounds and use thereof |
| WO2012120052A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
| EP2683705B1 (de) | 2011-03-08 | 2015-04-22 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| US8871758B2 (en) | 2011-03-08 | 2014-10-28 | Sanofi | Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof |
| WO2012120050A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
| EP2683703B1 (de) | 2011-03-08 | 2015-05-27 | Sanofi | Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
| US8710050B2 (en) | 2011-03-08 | 2014-04-29 | Sanofi | Di and tri- substituted oxathiazine derivatives, method for the production, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
| CN104321325B (zh) | 2012-05-24 | 2016-11-16 | 诺华股份有限公司 | 吡咯并吡咯烷酮化合物 |
| US9403827B2 (en) | 2013-01-22 | 2016-08-02 | Novartis Ag | Substituted purinone compounds |
| US9556180B2 (en) | 2013-01-22 | 2017-01-31 | Novartis Ag | Pyrazolo[3,4-d]pyrimidinone compounds as inhibitors of the P53/MDM2 interaction |
| EA029312B1 (ru) * | 2013-05-27 | 2018-03-30 | Новартис Аг | Производные имидазопирролидинона и их применение при лечении заболеваний |
| KR20160012197A (ko) | 2013-05-28 | 2016-02-02 | 노파르티스 아게 | 피라졸로-피롤리딘-4-온 유도체 및 질환의 치료에서의 그의 용도 |
| MX2015016421A (es) | 2013-05-28 | 2016-03-03 | Novartis Ag | Derivados de pirazolo-pirrolidin-4-ona como inhibidores de bet y su uso en el tratamiento de enfermedades. |
| AU2014351413B2 (en) | 2013-11-21 | 2017-06-01 | Novartis Ag | Pyrrolopyrrolone derivatives and their use as BET inhibitors |
| RU2766139C2 (ru) * | 2016-03-11 | 2022-02-08 | Ац Иммуне Са | Бициклические соединения для диагностики и лечения |
| CN105878251B (zh) * | 2016-04-22 | 2019-04-09 | 上海市同济医院 | 帕金森病动物模型的制备方法及其用途 |
| EP3630775B1 (en) * | 2017-05-31 | 2022-12-14 | ChemoCentryx, Inc. | 6-5 FUSED RINGS AS C5a INHIBITORS |
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| EP3728203B1 (en) | 2017-12-22 | 2024-03-13 | ChemoCentryx, Inc. | DIARYL SUBSTITUTED 6,5-FUSED RING COMPOUNDS AS C5aR INHIBITORS |
| US10759807B2 (en) | 2017-12-22 | 2020-09-01 | Chemocentryx, Inc. | Diaryl substituted 5,5-fused ring compounds as C5aR inhibitors |
| CA3175602A1 (en) * | 2020-05-07 | 2021-11-11 | Jerome Molette | Novel compounds for diagnosis |
| CN117460731A (zh) * | 2021-06-11 | 2024-01-26 | 劲方医药科技(上海)有限公司 | 杂环内酰胺类化合物，其制法与医药上的用途 |
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2004
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- 2004-04-13 CN CNA2004800175674A patent/CN1809566A/zh active Pending
- 2004-04-13 AT AT04727076T patent/ATE409700T1/de not_active IP Right Cessation
- 2004-04-13 AU AU2004232552A patent/AU2004232552A1/en not_active Abandoned
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- 2004-04-13 EA EA200501504A patent/EA200501504A1/ru unknown
- 2004-04-13 MX MXPA05011454A patent/MXPA05011454A/es unknown
- 2004-04-13 KR KR1020057020010A patent/KR20060006048A/ko not_active Ceased
- 2004-04-13 BR BRPI0409791-2A patent/BRPI0409791A/pt not_active IP Right Cessation
- 2004-04-13 WO PCT/IB2004/001357 patent/WO2004094421A1/en not_active Ceased
- 2004-04-13 OA OA1200500291A patent/OA13047A/en unknown
- 2004-04-13 CA CA002521538A patent/CA2521538A1/en not_active Abandoned
- 2004-04-13 AP AP2005003427A patent/AP2005003427A0/xx unknown
- 2004-04-16 CL CL200400827A patent/CL2004000827A1/es unknown
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- 2004-04-20 PE PE2004000389A patent/PE20050419A1/es not_active Application Discontinuation
- 2004-04-20 PA PA20048600601A patent/PA8600601A1/es unknown
- 2004-04-21 AR ARP040101339A patent/AR044037A1/es unknown
- 2004-04-21 UY UY28276A patent/UY28276A1/es not_active Application Discontinuation
- 2004-04-22 TW TW093111297A patent/TW200510419A/zh unknown
- 2004-04-23 NL NL1026027A patent/NL1026027C2/nl not_active IP Right Cessation
-
2005
- 2005-09-29 IS IS8054A patent/IS8054A/is unknown
- 2005-10-21 TN TNP2005000272A patent/TNSN05272A1/fr unknown
- 2005-10-21 ZA ZA200508568A patent/ZA200508568B/en unknown
- 2005-10-21 MA MA28565A patent/MA27766A1/fr unknown
- 2005-10-21 EC EC2005006117A patent/ECSP056117A/es unknown
- 2005-10-21 CO CO05106974A patent/CO5640084A2/es not_active Application Discontinuation
- 2005-11-22 NO NO20055516A patent/NO20055516L/no not_active Application Discontinuation
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20200139751A (ko) * | 2018-04-02 | 2020-12-14 | 케모센트릭스, 인크. | 융합된-바이사이클릭 C5aR 길항제의 프로드러그 |
Also Published As
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|---|---|
| AU2004232552A1 (en) | 2004-11-04 |
| DE602004016839D1 (de) | 2008-11-13 |
| ZA200508568B (en) | 2007-04-25 |
| TNSN05272A1 (fr) | 2007-07-10 |
| JP2006524225A (ja) | 2006-10-26 |
| MA27766A1 (fr) | 2006-02-01 |
| UY28276A1 (es) | 2004-11-30 |
| NL1026027A1 (nl) | 2004-10-27 |
| EA200501504A1 (ru) | 2006-04-28 |
| AP2005003427A0 (en) | 2005-12-31 |
| ES2309517T3 (es) | 2008-12-16 |
| IS8054A (is) | 2005-09-29 |
| GT200400076A (es) | 2004-12-16 |
| CL2004000827A1 (es) | 2005-03-04 |
| EP1622903B1 (en) | 2008-10-01 |
| US20040214856A1 (en) | 2004-10-28 |
| EP1622903A1 (en) | 2006-02-08 |
| ECSP056117A (es) | 2006-03-01 |
| PE20050419A1 (es) | 2005-06-18 |
| CN1809566A (zh) | 2006-07-26 |
| OA13047A (en) | 2006-11-10 |
| TW200510419A (en) | 2005-03-16 |
| NL1026027C2 (nl) | 2005-07-05 |
| NO20055516L (no) | 2005-11-22 |
| MXPA05011454A (es) | 2005-12-12 |
| PA8600601A1 (es) | 2005-05-24 |
| AR044037A1 (es) | 2005-08-24 |
| CO5640084A2 (es) | 2006-05-31 |
| BRPI0409791A (pt) | 2006-05-30 |
| CA2521538A1 (en) | 2004-11-04 |
| ATE409700T1 (de) | 2008-10-15 |
| WO2004094421A1 (en) | 2004-11-04 |
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