KR20050098876A - 개선된 능력을 갖는 화학적 억제기 및 이의 사용 방법 - Google Patents
개선된 능력을 갖는 화학적 억제기 및 이의 사용 방법 Download PDFInfo
- Publication number
- KR20050098876A KR20050098876A KR1020057014088A KR20057014088A KR20050098876A KR 20050098876 A KR20050098876 A KR 20050098876A KR 1020057014088 A KR1020057014088 A KR 1020057014088A KR 20057014088 A KR20057014088 A KR 20057014088A KR 20050098876 A KR20050098876 A KR 20050098876A
- Authority
- KR
- South Korea
- Prior art keywords
- flow channel
- ion exchange
- ion
- sample stream
- ions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000000034 method Methods 0.000 title claims abstract description 23
- 239000000126 substance Substances 0.000 title description 13
- 150000002500 ions Chemical class 0.000 claims abstract description 204
- 238000005342 ion exchange Methods 0.000 claims abstract description 77
- 239000011159 matrix material Substances 0.000 claims abstract description 70
- 238000012856 packing Methods 0.000 claims abstract description 44
- 239000012491 analyte Substances 0.000 claims abstract description 42
- 239000003014 ion exchange membrane Substances 0.000 claims abstract description 34
- 239000012528 membrane Substances 0.000 claims description 36
- 238000004587 chromatography analysis Methods 0.000 claims description 27
- 239000000463 material Substances 0.000 claims description 11
- 230000007935 neutral effect Effects 0.000 claims description 10
- 238000004891 communication Methods 0.000 claims description 9
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- 239000012530 fluid Substances 0.000 claims description 8
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- 230000000903 blocking effect Effects 0.000 claims description 5
- 238000012545 processing Methods 0.000 claims description 2
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- 239000003480 eluent Substances 0.000 description 36
- 239000003112 inhibitor Substances 0.000 description 33
- 230000001172 regenerating effect Effects 0.000 description 27
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 24
- 238000004458 analytical method Methods 0.000 description 12
- 150000001768 cations Chemical class 0.000 description 12
- 238000004255 ion exchange chromatography Methods 0.000 description 11
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 10
- 238000005341 cation exchange Methods 0.000 description 10
- 150000001450 anions Chemical class 0.000 description 9
- 239000003792 electrolyte Substances 0.000 description 9
- 239000000243 solution Substances 0.000 description 9
- HNSDLXPSAYFUHK-UHFFFAOYSA-N 1,4-bis(2-ethylhexyl) sulfosuccinate Chemical compound CCCCC(CC)COC(=O)CC(S(O)(=O)=O)C(=O)OCC(CC)CCCC HNSDLXPSAYFUHK-UHFFFAOYSA-N 0.000 description 8
- -1 hydroxide ions Chemical class 0.000 description 8
- 238000000926 separation method Methods 0.000 description 6
- 239000002904 solvent Substances 0.000 description 6
- 238000001514 detection method Methods 0.000 description 5
- 230000002401 inhibitory effect Effects 0.000 description 5
- 239000002245 particle Substances 0.000 description 5
- 230000008929 regeneration Effects 0.000 description 5
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- 230000002829 reductive effect Effects 0.000 description 4
- 239000011734 sodium Substances 0.000 description 4
- 239000000758 substrate Substances 0.000 description 4
- 239000004698 Polyethylene Substances 0.000 description 3
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 description 3
- 239000003011 anion exchange membrane Substances 0.000 description 3
- 239000011324 bead Substances 0.000 description 3
- 239000013000 chemical inhibitor Substances 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 238000000909 electrodialysis Methods 0.000 description 3
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- 239000012492 regenerant Substances 0.000 description 3
- 230000000717 retained effect Effects 0.000 description 3
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 description 2
- SLBOQBILGNEPEB-UHFFFAOYSA-N 1-chloroprop-2-enylbenzene Chemical compound C=CC(Cl)C1=CC=CC=C1 SLBOQBILGNEPEB-UHFFFAOYSA-N 0.000 description 2
- 239000004696 Poly ether ether ketone Substances 0.000 description 2
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 2
- 235000011114 ammonium hydroxide Nutrition 0.000 description 2
- 239000003153 chemical reaction reagent Substances 0.000 description 2
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- 229920003303 ion-exchange polymer Polymers 0.000 description 2
- 230000014759 maintenance of location Effects 0.000 description 2
- 229920002530 polyetherether ketone Polymers 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 238000005086 pumping Methods 0.000 description 2
- 229910001415 sodium ion Inorganic materials 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- VDZOOKBUILJEDG-UHFFFAOYSA-M tetrabutylammonium hydroxide Chemical compound [OH-].CCCC[N+](CCCC)(CCCC)CCCC VDZOOKBUILJEDG-UHFFFAOYSA-M 0.000 description 2
- GETQZCLCWQTVFV-UHFFFAOYSA-N trimethylamine Chemical compound CN(C)C GETQZCLCWQTVFV-UHFFFAOYSA-N 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- KEQGZUUPPQEDPF-UHFFFAOYSA-N 1,3-dichloro-5,5-dimethylimidazolidine-2,4-dione Chemical compound CC1(C)N(Cl)C(=O)N(Cl)C1=O KEQGZUUPPQEDPF-UHFFFAOYSA-N 0.000 description 1
- KGIGUEBEKRSTEW-UHFFFAOYSA-N 2-vinylpyridine Chemical compound C=CC1=CC=CC=N1 KGIGUEBEKRSTEW-UHFFFAOYSA-N 0.000 description 1
- JLBJTVDPSNHSKJ-UHFFFAOYSA-N 4-Methylstyrene Chemical compound CC1=CC=C(C=C)C=C1 JLBJTVDPSNHSKJ-UHFFFAOYSA-N 0.000 description 1
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 description 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- UEEJHVSXFDXPFK-UHFFFAOYSA-N N-dimethylaminoethanol Chemical compound CN(C)CCO UEEJHVSXFDXPFK-UHFFFAOYSA-N 0.000 description 1
- 108091034117 Oligonucleotide Proteins 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 description 1
- FKNQFGJONOIPTF-UHFFFAOYSA-N Sodium cation Chemical class [Na+] FKNQFGJONOIPTF-UHFFFAOYSA-N 0.000 description 1
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 125000005210 alkyl ammonium group Chemical group 0.000 description 1
- 239000000908 ammonium hydroxide Substances 0.000 description 1
- 238000005349 anion exchange Methods 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 239000002585 base Substances 0.000 description 1
- 229920005601 base polymer Polymers 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 235000013361 beverage Nutrition 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- XTHPWXDJESJLNJ-UHFFFAOYSA-N chlorosulfonic acid Substances OS(Cl)(=O)=O XTHPWXDJESJLNJ-UHFFFAOYSA-N 0.000 description 1
- 239000012539 chromatography resin Substances 0.000 description 1
- 239000011243 crosslinked material Substances 0.000 description 1
- 229960002887 deanol Drugs 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 239000012972 dimethylethanolamine Substances 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 239000003651 drinking water Substances 0.000 description 1
- 235000020188 drinking water Nutrition 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- VEWLDLAARDMXSB-UHFFFAOYSA-N ethenyl sulfate;hydron Chemical compound OS(=O)(=O)OC=C VEWLDLAARDMXSB-UHFFFAOYSA-N 0.000 description 1
- 239000012510 hollow fiber Substances 0.000 description 1
- 239000003317 industrial substance Substances 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 230000037427 ion transport Effects 0.000 description 1
- 229910000000 metal hydroxide Inorganic materials 0.000 description 1
- 230000005012 migration Effects 0.000 description 1
- 238000013508 migration Methods 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000012811 non-conductive material Substances 0.000 description 1
- 229920001542 oligosaccharide Polymers 0.000 description 1
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- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 1
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- 229920000915 polyvinyl chloride Polymers 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- 235000017550 sodium carbonate Nutrition 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000007480 spreading Effects 0.000 description 1
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- 229940117958 vinyl acetate Drugs 0.000 description 1
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/96—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation using ion-exchange
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
- B01D15/367—Ion-suppression
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/42—Electrodialysis; Electro-osmosis ; Electro-ultrafiltration; Membrane capacitive deionization
- B01D61/44—Ion-selective electrodialysis
- B01D61/46—Apparatus therefor
- B01D61/48—Apparatus therefor having one or more compartments filled with ion-exchange material, e.g. electrodeionisation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/42—Electrodialysis; Electro-osmosis ; Electro-ultrafiltration; Membrane capacitive deionization
- B01D61/44—Ion-selective electrodialysis
- B01D61/52—Accessories; Auxiliary operation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/42—Electrodialysis; Electro-osmosis ; Electro-ultrafiltration; Membrane capacitive deionization
- B01D61/44—Ion-selective electrodialysis
- B01D61/54—Controlling or regulating
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2325/00—Details relating to properties of membranes
- B01D2325/42—Ion-exchange membranes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
Landscapes
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Water Supply & Treatment (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/356,345 | 2003-01-30 | ||
| US10/356,345 US7517696B2 (en) | 2003-01-30 | 2003-01-30 | Chemical suppressors and method of use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20050098876A true KR20050098876A (ko) | 2005-10-12 |
Family
ID=32770777
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020057014088A Withdrawn KR20050098876A (ko) | 2003-01-30 | 2003-12-09 | 개선된 능력을 갖는 화학적 억제기 및 이의 사용 방법 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US7517696B2 (enExample) |
| EP (1) | EP1587597B1 (enExample) |
| JP (1) | JP4485368B2 (enExample) |
| KR (1) | KR20050098876A (enExample) |
| CN (1) | CN1764493A (enExample) |
| AU (1) | AU2003296431B2 (enExample) |
| CA (1) | CA2514844C (enExample) |
| WO (1) | WO2004070377A2 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6752927B2 (en) * | 2001-03-01 | 2004-06-22 | Dionex Corporation | Suppressed chromatography and salt conversion system |
| US8216515B2 (en) * | 2004-09-16 | 2012-07-10 | Dionex Corporation | Capillary ion chromatography |
| US7618826B2 (en) * | 2006-09-19 | 2009-11-17 | Dionex Corporation | Membrane suppressor with an outlet substantially non-retentive for ionic species |
| WO2013028922A1 (en) | 2011-08-23 | 2013-02-28 | Board Of Regents, The University Of Texas System | Three- electrode buffer generator and method |
| WO2013067509A1 (en) | 2011-11-04 | 2013-05-10 | Bio-Rad Laboratories, Inc. | Simultaneous purification of cell components |
| US9766207B2 (en) | 2011-11-04 | 2017-09-19 | Bio-Rad Laboratories, Inc. | Affinity methods and compositions employing electronic control of pH |
| US9658195B2 (en) | 2012-02-15 | 2017-05-23 | Bio-Rad Laboratories, Inc. | Electronic control of pH and ionic strength |
| US9321012B2 (en) | 2012-04-04 | 2016-04-26 | Bio-Rad Laboratories, Inc. | Electronic protein fractionation |
| US10048233B2 (en) | 2012-11-12 | 2018-08-14 | Dionex Corporation | Suppressor device |
| US9914651B2 (en) | 2013-05-08 | 2018-03-13 | Dionex Corporation | Current efficient electrolytic device and method |
| EP3126038B1 (en) | 2014-04-02 | 2021-06-02 | Mangrove Water Technologies Ltd. | Conversion of gas and treatment of a solution |
| CN104007219B (zh) * | 2014-06-05 | 2016-03-30 | 浙江省中医药研究院 | 一种液相色谱-酶电极联用装置及其应用 |
| US9400268B2 (en) * | 2014-08-08 | 2016-07-26 | Dionex Corporation | Method for reducing suppressor noise |
| US20160137530A1 (en) | 2014-11-13 | 2016-05-19 | Dionex Corporation | Ion exchange based volatile component removal device for ion chromatography |
| US10175211B2 (en) * | 2014-12-31 | 2019-01-08 | Dionex Corporation | Current-efficient suppressor and pretreatment device and method |
| US10416137B2 (en) * | 2016-09-07 | 2019-09-17 | Board Of Regents, University Of Texas System | Electrodialytic capillary suppressor for suppressed conductometric ion chromatography |
| US10948466B2 (en) * | 2017-03-03 | 2021-03-16 | Dionex Corporation | Flow control in an electrolytic reagent concentrator for ion chromatography |
| US11243194B2 (en) | 2019-01-25 | 2022-02-08 | Dionex Corporation | Suppressors with eluent screens for use in ion chromatography |
| CN111214848B (zh) * | 2020-01-20 | 2020-11-20 | 青岛盛瀚色谱技术有限公司 | 一种离子色谱抑制器 |
| CN115103819B (zh) * | 2020-02-18 | 2023-11-21 | 株式会社F.C.C. | 离子交换装置 |
| US20230184728A1 (en) * | 2021-12-09 | 2023-06-15 | Dionex Corporation | Suppressor |
| CN114894942B (zh) * | 2022-03-16 | 2024-04-05 | 中国石油化工股份有限公司 | 一种快速检测醇胺溶液中热稳盐阴离子的装置及方法 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3920397A (en) * | 1973-08-06 | 1975-11-18 | Dow Chemical Co | Apparatus and method for quantitative analysis of ionic species by liquid column chromatography |
| US3926559A (en) * | 1973-08-06 | 1975-12-16 | Dow Chemical Co | Method and apparatus for quantitative chromatographic analysis of cationic species |
| US3925019A (en) * | 1973-08-06 | 1975-12-09 | Dow Chemical Co | Chromatographic analysis of ionic species |
| US3897213A (en) * | 1973-08-06 | 1975-07-29 | Dow Chemical Co | Automated quantitative analysis of ionic species |
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-
2003
- 2003-01-30 US US10/356,345 patent/US7517696B2/en not_active Expired - Lifetime
- 2003-12-09 CA CA2514844A patent/CA2514844C/en not_active Expired - Fee Related
- 2003-12-09 EP EP03815773.1A patent/EP1587597B1/en not_active Expired - Lifetime
- 2003-12-09 KR KR1020057014088A patent/KR20050098876A/ko not_active Withdrawn
- 2003-12-09 AU AU2003296431A patent/AU2003296431B2/en not_active Ceased
- 2003-12-09 JP JP2004568022A patent/JP4485368B2/ja not_active Expired - Lifetime
- 2003-12-09 WO PCT/US2003/039219 patent/WO2004070377A2/en not_active Ceased
- 2003-12-09 CN CNA2003801102229A patent/CN1764493A/zh active Pending
-
2009
- 2009-03-04 US US12/398,095 patent/US20090166293A1/en not_active Abandoned
-
2012
- 2012-02-08 US US13/368,663 patent/US8636963B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2514844C (en) | 2010-09-14 |
| CA2514844A1 (en) | 2004-08-19 |
| US20040149581A1 (en) | 2004-08-05 |
| AU2003296431B2 (en) | 2009-07-16 |
| US20120141328A1 (en) | 2012-06-07 |
| US8636963B2 (en) | 2014-01-28 |
| US20090166293A1 (en) | 2009-07-02 |
| WO2004070377A3 (en) | 2005-01-13 |
| JP4485368B2 (ja) | 2010-06-23 |
| AU2003296431A1 (en) | 2004-08-30 |
| US7517696B2 (en) | 2009-04-14 |
| EP1587597B1 (en) | 2019-01-23 |
| WO2004070377A2 (en) | 2004-08-19 |
| CN1764493A (zh) | 2006-04-26 |
| JP2006514279A (ja) | 2006-04-27 |
| EP1587597A2 (en) | 2005-10-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
Patent event date: 20050729 Patent event code: PA01051R01D Comment text: International Patent Application |
|
| PG1501 | Laying open of application | ||
| PC1203 | Withdrawal of no request for examination | ||
| WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |