KR20050086924A - Hpv-16 l1 vlp 및 hpv-18 l1 vlp 백신 - Google Patents

Hpv-16 l1 vlp 및 hpv-18 l1 vlp 백신 Download PDF

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Publication number
KR20050086924A
KR20050086924A KR1020057011497A KR20057011497A KR20050086924A KR 20050086924 A KR20050086924 A KR 20050086924A KR 1020057011497 A KR1020057011497 A KR 1020057011497A KR 20057011497 A KR20057011497 A KR 20057011497A KR 20050086924 A KR20050086924 A KR 20050086924A
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South Korea
Prior art keywords
hpv
vlps
types
groups
group
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Ceased
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KR1020057011497A
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English (en)
Korean (ko)
Inventor
게리 두빈
브루스 인니스
몬세프 모하메드 슬라오우이
마틴 앤 세실 웨텐도르프
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글락소스미스클라인 바이오로지칼즈 에스.에이.
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Publication of KR20050086924A publication Critical patent/KR20050086924A/ko
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5258Virus-like particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55572Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/20011Papillomaviridae
    • C12N2710/20022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/20011Papillomaviridae
    • C12N2710/20023Virus like particles [VLP]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/20011Papillomaviridae
    • C12N2710/20034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020057011497A 2002-12-20 2003-12-18 Hpv-16 l1 vlp 및 hpv-18 l1 vlp 백신 Ceased KR20050086924A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US43503502P 2002-12-20 2002-12-20
US60/435,035 2002-12-20
US49665303P 2003-08-20 2003-08-20
US60/496,653 2003-08-20

Related Child Applications (2)

Application Number Title Priority Date Filing Date
KR1020127026719A Division KR20120118087A (ko) 2002-12-20 2003-12-18 Hpv-16 l1 vlp 및 hpv-18 l1 vlp 백신
KR1020127027784A Division KR101361769B1 (ko) 2002-12-20 2003-12-18 Hpv-16 l1 vlp 및 hpv-18 l1 vlp 백신

Publications (1)

Publication Number Publication Date
KR20050086924A true KR20050086924A (ko) 2005-08-30

Family

ID=32685362

Family Applications (3)

Application Number Title Priority Date Filing Date
KR1020057011497A Ceased KR20050086924A (ko) 2002-12-20 2003-12-18 Hpv-16 l1 vlp 및 hpv-18 l1 vlp 백신
KR1020127027784A Expired - Lifetime KR101361769B1 (ko) 2002-12-20 2003-12-18 Hpv-16 l1 vlp 및 hpv-18 l1 vlp 백신
KR1020127026719A Withdrawn KR20120118087A (ko) 2002-12-20 2003-12-18 Hpv-16 l1 vlp 및 hpv-18 l1 vlp 백신

Family Applications After (2)

Application Number Title Priority Date Filing Date
KR1020127027784A Expired - Lifetime KR101361769B1 (ko) 2002-12-20 2003-12-18 Hpv-16 l1 vlp 및 hpv-18 l1 vlp 백신
KR1020127026719A Withdrawn KR20120118087A (ko) 2002-12-20 2003-12-18 Hpv-16 l1 vlp 및 hpv-18 l1 vlp 백신

Country Status (28)

Country Link
US (2) US20060251676A1 (https=)
EP (1) EP1572233B1 (https=)
JP (1) JP5475939B2 (https=)
KR (3) KR20050086924A (https=)
AP (1) AP2005003347A0 (https=)
AR (1) AR042530A1 (https=)
AT (1) ATE503492T1 (https=)
AU (1) AU2003293942B2 (https=)
BE (3) BE2015C068I2 (https=)
BR (1) BR0317544A (https=)
CA (1) CA2510457C (https=)
CY (1) CY1111552T1 (https=)
DE (1) DE60336581D1 (https=)
DK (1) DK1572233T3 (https=)
EA (2) EA200701633A1 (https=)
EC (1) ECSP055869A (https=)
IL (1) IL169085A (https=)
IS (1) IS2811B (https=)
MA (1) MA27581A1 (https=)
MX (1) MXPA05006764A (https=)
MY (1) MY144492A (https=)
NO (1) NO20052846L (https=)
NZ (1) NZ540811A (https=)
OA (1) OA13147A (https=)
PL (1) PL215257B1 (https=)
PT (1) PT1572233E (https=)
TW (1) TWI349557B (https=)
WO (1) WO2004056389A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20130083426A (ko) * 2009-06-19 2013-07-22 아이진 주식회사 자궁경부암 백신

Families Citing this family (19)

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KR100629028B1 (ko) * 1998-10-16 2006-09-26 글락소스미스클라인 바이오로지칼즈 에스.에이. 애쥬번트 시스템 및 백신
GB0206360D0 (en) 2002-03-18 2002-05-01 Glaxosmithkline Biolog Sa Viral antigens
US7858098B2 (en) 2002-12-20 2010-12-28 Glaxosmithkline Biologicals, S.A. Vaccine
JP2008502633A (ja) * 2004-06-16 2008-01-31 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム Hpv16およびhpv18ならびにhpv31、45または52から選ばれる少なくとも1つの別のhpv型に対するワクチン
US7758866B2 (en) 2004-06-16 2010-07-20 Glaxosmithkline Biologicals, S.A. Vaccine against HPV16 and HPV18 and at least another HPV type selected from HPV 31, 45 or 52
EP1877087B1 (en) 2005-04-15 2013-02-20 GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Methods and compositions for producing an enhanced immune response to a human papillomavirus immunogen
AR053715A1 (es) * 2005-04-26 2007-05-16 Glaxosmithkline Biolog Sa Vacuna multivalente de vph
WO2006114312A2 (en) * 2005-04-26 2006-11-02 Glaxosmithkline Biologicals S.A. Vaccine
WO2008134935A1 (en) 2007-04-29 2008-11-13 Beijing Wantai Biological Pharmacy Enterprise Co., Ltd. Truncated human papillomavirus type 18 l1 proteins
US9428555B2 (en) 2007-04-29 2016-08-30 Beijing Wantai Biological Pharmacy Enterprise Co., Ltd. Truncated L1 protein of Human Papillomavirus type 16
DK2403507T3 (en) * 2009-03-05 2018-06-06 Jenny Colleen Mccloskey TREATMENT OF INFECTION
US20170212116A1 (en) 2014-01-31 2017-07-27 Ulisse Biomed Srl Biosensors for the detection of infection and associated maladies
US10799574B2 (en) 2014-10-24 2020-10-13 Hpvvax. Llc Method and composition for treating cancer or skin lesion using a vaccine
CN107001430A (zh) 2014-10-24 2017-08-01 哈普威克斯有限责任公司 癌症和皮肤病变治疗
WO2016194685A1 (ja) * 2015-06-02 2016-12-08 テルモ株式会社 アルミニウムを含有するアジュバント組成物およびこれを含むワクチン組成物
KR20250136930A (ko) 2018-03-06 2025-09-16 프레시전 인코포레이티드 사람 파필로마바이러스 백신 및 이의 용도
IL277128B2 (en) 2018-03-06 2025-11-01 Precigen Inc Hepatitis b vaccines and uses of the same
WO2019233412A1 (zh) * 2018-06-04 2019-12-12 厦门大学 一种人乳头瘤病毒18型l1蛋白的突变体
WO2020117715A1 (en) 2018-12-03 2020-06-11 Board Of Regents, The University Of Texas System Oligo-benzamide analogs and their use in cancer treatment

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DE4332596A1 (de) * 1993-09-24 1995-03-30 Martin Josef Dr Sapp Monoklonale Antikörper
EP1015561B1 (en) 1997-09-05 2006-07-19 Medimmune, Inc. In vitro method for disassembly/reassembly of papillomavirus virus-like particles (vlps)
AU764138B2 (en) * 1999-02-05 2003-08-14 Merck Sharp & Dohme Corp. Human papilloma virus vaccine formulations
US6245568B1 (en) 1999-03-26 2001-06-12 Merck & Co., Inc. Human papilloma virus vaccine with disassembled and reassembled virus-like particles
GB9921146D0 (en) * 1999-09-07 1999-11-10 Smithkline Beecham Biolog Novel composition
US6908613B2 (en) * 2000-06-21 2005-06-21 Medimmune, Inc. Chimeric human papillomavirus (HPV) L1 molecules and uses therefor
NZ523408A (en) * 2000-06-26 2006-02-24 Stressgen Biotechnologies Corp Human papilloma virus treatment

Cited By (1)

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Publication number Priority date Publication date Assignee Title
KR20130083426A (ko) * 2009-06-19 2013-07-22 아이진 주식회사 자궁경부암 백신

Also Published As

Publication number Publication date
ATE503492T1 (de) 2011-04-15
US20060251676A1 (en) 2006-11-09
BR0317544A (pt) 2005-11-22
KR20120118087A (ko) 2012-10-25
CY1111552T1 (el) 2015-08-05
IS7885A (is) 2005-06-09
EP1572233A1 (en) 2005-09-14
TW200423957A (en) 2004-11-16
IL169085A0 (en) 2007-07-04
TWI349557B (en) 2011-10-01
OA13147A (en) 2006-12-13
HK1085378A1 (en) 2006-08-25
DK1572233T3 (da) 2011-06-27
PT1572233E (pt) 2011-06-07
AP2005003347A0 (en) 2005-06-30
AR042530A1 (es) 2005-06-22
BE2015C069I2 (https=) 2024-08-08
KR20120123616A (ko) 2012-11-08
KR101361769B1 (ko) 2014-02-10
AU2003293942B2 (en) 2009-12-10
WO2004056389A1 (en) 2004-07-08
BE2015C067I2 (https=) 2024-08-08
IL169085A (en) 2014-04-30
CA2510457A1 (en) 2004-07-08
EA200701633A1 (ru) 2007-12-28
NZ540811A (en) 2007-03-30
JP2006512413A (ja) 2006-04-13
ECSP055869A (es) 2005-09-20
EA009179B1 (ru) 2007-12-28
AU2003293942A1 (en) 2004-07-14
CA2510457C (en) 2011-12-06
BE2015C068I2 (https=) 2024-08-08
JP5475939B2 (ja) 2014-04-16
EP1572233B1 (en) 2011-03-30
IS2811B (is) 2012-11-15
MY144492A (en) 2011-09-30
MA27581A1 (fr) 2005-10-03
PL377710A1 (pl) 2006-02-06
US20050287161A1 (en) 2005-12-29
DE60336581D1 (de) 2011-05-12
PL215257B1 (pl) 2013-11-29
NO20052846L (no) 2005-07-13
MXPA05006764A (es) 2005-09-08
EA200500834A1 (ru) 2006-02-24

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