KR20040039663A - cosmectics for prerention and improvement of atopic dermatitis and manufacturing method therefor - Google Patents

Abstract

PURPOSE: Provided is a cosmetics containing bamboo extract which shows excellent improving and preventing effects on atopic dermatitis including erythema, edema, pruritus, exudation and crusting, and a manufacturing method thereof. CONSTITUTION: A manufacturing method of cosmetics for the prevention and improvement of atopic dermatitis comprises the steps of: dissolving a water phase raw ingredient of and an oil phase raw ingredient of cosmetics, followed by mixing, defoaming, cooling to 45 deg.C and filtration to remove impurities to manufacture cosmetics; and adding 0.5-30 wt.% of bamboo extract to the cosmetics.

Description

Cosmectics for prerention and improvement of atopic dermatitis and manufacturing method therefor}

The present invention relates to a cosmetic that has a symptom relief and amelioration effect of atopic dermatitis patients, and more particularly, cosmetics such as water lotion, milk lotion, cream, etc., which contain an undiluted solution of bamboo, which is an extract extracted by heating bamboo. The present invention relates to a cosmetic preparation for preventing and improving atopic dermatitis having an excellent effect on improving and preventing atopic dermatitis.

Atopic skin is a type of skin inflammation characterized by erythema, edema, severe pruritis, exudation and crusting.

The acute phase forms blisters in the epidermis, while the chronic phase develops scaling and thickening of the skin. It is well known that genetic factors of atopic dermatitis are involved and have a family history of atopic dermatitis, asthma and allergic rhinitis in more than 50% of the patient family. Clinical observations show that foods such as eggs, milk, and flour are important allergens in young children, while indoors, dust, pollen, mold, and dandruff in hairy animals are the main causes in large children. The frequency of occurrence varies from 0.25-20% of the total population, and it is reported that the incidence of 11.2% in children under 6 years old in Korea. Atopic dermatitis takes the stages of first infancy and second childhood. Infancy symptoms begin 2-3 months after birth, which can cause redness and redness of the face and spread to the entire face, neck, limbs and whole body. Lesions of the limbs usually occur on the extension surface rather than on the flexion surface. About 75% of childhood atopic dermatitis is lost in two stones, and these children become resistant to foods that have caused allergies. However, about 25% of infants develop childhood atopic dermatitis and sometimes develop new ones. Chronicized lesions are passed on to adulthood as lichenification becomes more pronounced, but often heals in the 40s and 50s.

To date, atopic dermatitis has been treated with immunotherapy and pharmacotherapy, but there are no special treatments. If the symptoms are severe, steroids (adrenal corticosteroids) have been used, but they are effective only for short-term clinical symptoms. Most of the effects are induced. Long-term topical administration of steroids leads to a decrease in adrenal function, resulting in side effects caused by various corticosteroids, which is inappropriate for continuous use. As there is no appropriate treatment for atopic dermatitis patients, in many cases, depending on the constitution improvement, folk remedies, and herbal treatment, expect to alleviate the clinical symptoms and treatment effect, but until now, the treatment or skin coating agent that can be used without long-term side effects has been developed. It didn't work.

Therefore, for atopic dermatitis patients gradually increasing due to environmental changes and industrialization, the development of external preparations without side effects after long-term use is urgently required.

Recently, external preparations including substances that have symptomatic and therapeutic effects using herbal medicines have been used, but the effects are not meeting expectations.

The present invention has been made in order to solve this problem, by adding a extract extracted by heating bamboo (bamboo) by manufacturing a cosmetic, atopic dermatitis prevention and improvement cosmetics having an excellent effect on the improvement and prevention of atopic dermatitis And to provide a method for producing the object.

1 is a process chart showing a water lotion manufacturing process by the manufacturing method of the present invention.

Figure 2 is a process chart showing a mill lotion manufacturing process according to the production method of the present invention.

Figure 3 is a process chart showing a cream manufacturing process by the manufacturing method of the present invention.

In order to achieve the above object, the present invention in the cosmetics prepared by dissolving, mixing, degassing and cooling the water raw material and the oily raw material which is a common cosmetic raw material, by mixing 0.5 ~ 30% by weight of the extract extracted from bamboo It was created.

Looking at the manufacturing process for manufacturing such cosmetics,

A mixing step of melting and mixing each of the water and raw materials, which are common cosmetic raw materials;

A degassing step of removing bubbles in the mixture;

A cooling step of cooling the degassed mixture to 45 ° C;

In the cosmetic manufacturing method consisting of a filtration step to remove foreign matter,

The bamboo is heated to a high temperature to extract a liquid bamboo extract, which comprises a bamboo extract addition step of mixing 0.5 to 30% by weight to the mixture through the cooling process.

Hereinafter, embodiments of the present invention will be described in detail with reference to the accompanying drawings.

Table 1 below shows the composition when preparing the water lotion and milk lotion, cream by the production method of the present invention.

Classification Water lotion (% by weight) Milk Croissant cream Award material Beta Glucan (2) Hyaluronic Acid (2) aminocoat (3) Ennacomplex 262 (3) Beta Glucan (2) phytocollagen (5) D-panthenol (2) Aloe Extracts (3) unimoist U-125 (5) vitamin E acetat (0.2) Ennacomplex 262 (3) Na-Hyaluronate (3) vitamin E acetate (0.2) allantoin (2) dipotassiumglycyrrhizate (1) vitamin E acetate (0.2) Paid raw materials vaseline (5) vaseline (10) phytosterol (8) phytosterol (8) squalane (8) squalane (13) Vegetable Ceramides (2) Vegetable Ceramides (2) additive Bamboo Extract (3) Bamboo Extract (3) Bamboo Extract (3) Ingredient Paraoxybenzoic acid ester (proper) Paraoxybenzoic acid ester (proper) Paraoxybenzoic acid ester (proper) Emulsifier Vegetable surfactant (appropriate) Vegetable surfactant (appropriate) Purified Water to 100 Purified Water to 100 Purified Water to 100

Example 1 A water lotion was prepared by the same process as shown in FIG.

As shown in Table 1, water raw materials are weighed and dissolved in a 75 ℃ water melting tank. After cooling to 45 ° C., add the additive force, mix strongly, and remove bubbles. After cooling down completely, it is filtered and stored in a container.

(Example 2) The milk lotion was prepared by the same process as shown in FIG.

As shown in Table 1, water and raw materials are weighed to dissolve the water in a 75 ℃ emulsifying kiln, and the oil is dissolved in an oil bath. After mixing the two ingredients strongly, emulsifier is added to emulsify, and then thickener is added to neutralize. After removing the bubbles and cooled to 45 ℃ and added 3% by weight of the bamboo extract as an additive and filtered.

Example 3 A cream was prepared by the same process as shown in FIG. 3 using the composition shown in Table 1 above.

As shown in Table 1, water and raw materials are weighed to dissolve the water in a 75 ℃ emulsifying kiln, and the oil is dissolved in an oil bath. The two materials are mixed strongly and emulsified by adding an emulsifier. After removing the bubbles and cooled to 45 ℃ and added 3% by weight of the bamboo extract as an additive and filtered.

Clinical trials conducted to confirm the effects of water lotion, milk lotion, and cream on atopic dermatitis patients were carried out to study the immune response of atopic diseases. This was done with the participation of the College of Basic Medicine and clinical specialists. Eighty patients were selected and divided into four groups of 20 patients in one group. For each group of 20 people, the effects of water lotion, milk lotion, and cream containing bamboo extract (throat) were observed.

Each patient was given a topical lotion, either milk lotion or cream, and applied to the affected area three times daily. After using, the effect was observed, and if necessary, the patient was visited individually to confirm the effect and the question was answered to summarize the results.

The content of the survey includes;

① User's address, name, name, age

② Start date and time of use of external preparation

③ How to use and frequency of use

④ Area of use and quantity

⑤ Atopic symptoms of the patient (time of onset, duration, severity, site, etc.)

⑥ Effect after use

⑦ Start of effect after use (after days from use)

⑧ When symptoms reappear (Symptoms appear after treatment stops)

⑨ Current state after use

부작용 Side effects of external preparation

⑪ impression

⑫ Suggestions and improvements, other

The questionnaire was collected between 10 days and 1 month after the spread of external preparations. Some patients were observed for more than 3 months to observe side effects and long-term effects on external preparations. In addition, some patients visited from time to time to check the change in the status of the photograph was used as data.

As a result of the above clinical trials, 77 (96.3%) of 80 atopic patients who participated in the experiment showed a great effect.

Therefore, similar effects were observed in the use of all formulations of the lotion, milk lotion, and cream form, indicating that the effect was due to the bamboo extract. In the case of patients who had been effective, most patients were able to reduce pruritus and normalize skin lesions regardless of the time of onset and the severity of symptoms. It was confirmed that 69 patients had reduced pruritus significantly before and after 10 days of use.

In addition, the cosmetics of the present invention has been confirmed that the progress of the effect in a completely different way from the steroid preparations used to date, so that the effect of the control method of other immunological factors other than the mechanism by steroids. In the first two days, there was no response at all, and after 3 days, sensible response (redness of use area) appeared in many patients. After 6 days of use, pruritus decreased and skin changes began to occur.

On the other hand, the bamboo bamboo, which is a heated bamboo extract used in the present invention, refers to a liquid in which medicine ingredients have flown directly or indirectly from bamboo, and are transparent and burnt in blue-yellow or yellow-brown juice. Critically used for stroke and high blood pressure, it can be used to squeeze phlegm and to treat stroke disorders and limb pain.

In the present invention, the indirect heating method was selected by placing in a container for 8 hours at a temperature of 120 ℃. Among the bamboos growing in our country, we took the year-ends of the kings grown in Damyang and used bamboo leaves and stems to heat them.

In addition, the basic ingredients in creams and lotions are used in general moisturizers and ointments, which are not related to the treatment of atopy, and are used for the protection of the skin barrier. Amino coat, Phytocollagen, Unimoist U-125, Na-Hyaluronate, Allantoin, Dipotassium Glycyrrhizate, Vaseline, Phytosterol, Squalane, Vitamin E Acetate and vegetable ceramide.

As described above, the present invention manufactures cosmetics, such as water lotion, milk lotion, cream, and the like, and extracts bamboo, and uses it on the skin of atopic patients, such as skin changes, pruritus changes, and the like according to the number of times and period of use. As a result of the observation, the effect of bamboo extract on atopic skin was confirmed.

As described above, the present invention produces cosmetics such as water lotion, milk lotion, cream, etc. by adding an extract extracted by heating bamboo, and has an excellent effect on improving and preventing atopic dermatitis.

Claims (2)

In order to achieve the above object, the present invention in the cosmetics prepared by dissolving, mixing, degassing and cooling the water raw material and the oily raw material which is a common cosmetic raw material, by mixing 0.5 ~ 30% by weight of the extract extracted from bamboo Cosmetics for the prevention and improvement of atopic dermatitis, characterized in that the composition. A mixing step of melting and mixing each of the water and raw materials, which are common cosmetic raw materials; A degassing step of removing bubbles in the mixture; A cooling step of cooling the degassed mixture to 45 ° C; In the cosmetic manufacturing method consisting of a filtration step to remove foreign matter, Heating bamboo to a high temperature to extract a liquid bamboo extract, and the process of the cosmetic treatment for atopic dermatitis, characterized in that it comprises a bamboo extract addition step of mixing 0.5 ~ 30% by weight to the mixture through the cooling process Manufacturing method.