KR20040033117A - Compositions for hair cosmetic containing nano-emulsion - Google Patents

Abstract

PURPOSE: Provided is a composition of a hair-care product containing a nano-emulsion which includes active ingredients to have scalp and hair care effects. CONSTITUTION: A composition of a hair-care product is characterized by containing, based on the total weight of the composition, 0.0005-10.0 wt.% of a nano-emulsion which includes lecithin saturated with 30-95 wt.% of phosphatidylcholine as well as bioactive compounds, as active ingredient. The bioactive compounds are selected from lipid soluble vitamins, such as vitamin A, vitamin D, vitamin E, and vitamin K, water soluble vitamins, such as vitamin C, vitamin B and vitamin PP, their derivatives, triclosan and salicylic acid.

Description

Composition for hair cosmetic containing nano-emulsion

The present invention relates to a cosmetic composition for hair containing a nanoemulsion in which the active ingredient for improving the health of the scalp and hair is collected. More specifically, the lecithin having a saturated fatty acid chain is used as the main surfactant, and the oil in the particles The present invention relates to a hair cosmetic composition containing a nanoemulsion stabilized by collecting an effective vitamin component and oil in a phase.

Our hair is stressed by damage factors such as frequent perming, dyeing, strong heat of dry and ultraviolet rays, and there have been many attempts to restore damaged hair and protect hair by supplying active ingredients to damaged hair. Furthermore, attempts are being made to fundamentally approach hair health through scalp care, which is the basis of hair.

In particular, many studies have been conducted to strengthen hair by supplying hair proteins or lipids to repair damaged hair, but there are still many mentions of vitamins, which are components of skin and hair, as representative ingredients for hair and scalp. It is recognized as the most effective ingredient. Panthenol, a vitamin B5 ingredient, is useful for many products due to its moisturizing and balancing effect. It is adsorbed on the hair cuticle layer, penetrates into the cortex, and penetrates the scalp to convert into pantothenic acid, which leads to hair root or skin. It will act as a micronutrient of. Vitamin A and its derivatives are also known to have a beneficial effect on dry skin where keratin occurs and helps to form keratin, the main component of hair.

Panthenol prevents hair from drying, especially with vitamin E derivatives to achieve proper moisturizing effect. This moisturizing effect prevents the hair from drying out and crumbles. Vitamin E derivatives act as antioxidants. Antioxidants act to prevent oxidation, preventing or delaying the oxidation of fats, fats and fats and their derivatives. Sebum on the scalp surface is broken down into free fatty acids and lipid peroxides. Among them, lipid peroxide may cause the dandruff production of the scalp and may cause aging. Vitamin E derivatives also act to reduce dandruff by inhibiting the production of lipid peroxide. In addition, as mentioned above, in combination with panthenol, it has a moderate moisturizing effect and also has anti-inflammatory action.

In addition, vitamin PP, known as niacinamide, which has an effective antioxidant effect on hair damage caused by dyeing and prevents hair from discoloring, also acts on the hair root to strengthen the hair root and contribute to hair production. Retinol, better known as a functional ingredient in skin aging prevention, is known to have a beneficial effect on dry skin where keratinization occurs by improving the deprivation of the scalp.

The vitamins and the like have been typically used in the hair and scalp and has shown a synergy effect when used with the vitamin components.

However, such a vitamin component is easily washed by a detergent in the formulation, especially in the case of fat-soluble vitamins, it is difficult to exist in a stable state, and the other effects have a disadvantage that its efficacy is reduced.

In order to solve the above problems and increase the efficacy effect of the vitamin component, the present inventors use a saturated lecithin as a surfactant and a hair cosmetic composition containing a nanoemulsion prepared by collecting various vitamin components inside the particles to absorb vitamins. It has been found to be effective in increasing the amount and promoting the health of hair.

Accordingly, an object of the present invention is to provide a nanoemulsion prepared by using saturated lecithin as a surfactant and trapping vitamin and oil components in the particles, and by containing the nanoemulsion, the penetration of the active ingredient is excellent, and thus To provide a cosmetic composition for hair that promotes health.

1 is a particle size distribution diagram of a nanoemulsion containing tocopherol acetate.

2 is a skin absorption test results of tocopherol acetate.

(A: Reference Example 1, B: Comparative Example 2, C: Example 1, D: Example 2)

(Reference Example 1: 2% solution in water)

3 is a skin absorption test results of tocopherol acetate.

(A: Reference Example 1, B: Comparative Example 4, C: Example 3, D: Example 4)

4 is a test result of the tensile strength of the hair.

(A: Comparative Example 1, B: Comparative Example 2, C: Example 1, D: Example 2)

5 is a test result of tensile strength of hair.

(A: Comparative Example 3, B: Comparative Example 4, C: Example 3, D: Example 4)

The present invention relates to a hair cosmetic composition comprising a nanoemulsion prepared by using lecithin having a saturated fatty acid chain as a main surfactant, and having an inside of the particle as an oil phase, which contains an effective vitamin component and oil in the oil phase, It is prepared by using a saturated lecithin containing a certain amount of phosphatidylcholine as a main surfactant and a nanoemulsion stabilized by using a co-surfactant together in the hair cosmetic composition.

First, a nanoemulsion according to the present invention is prepared.

In the present invention, the nanoemulsion refers to an emulsion in which the particles have a size in nanometers, and the preparation process is as follows:

Mixing and warming and dissolving the physiologically active ingredients such as saturated lecithin, oil and humectant, blood circulation promoter, bactericidal and antibacterial agent having a phosphatidylcholine content of 30 to 95% by weight;

Mixing and emulsifying the heated distilled water to the dissolved solution;

The emulsified emulsion comprises the steps of preparing a homogeneous nanoemulsion using a high pressure emulsifier, and through the above steps to prepare a nanoemulsion in which the inner phase is an oil phase and the outer phase is an aqueous phase.

Lecithin, which is the main surfactant used to prepare nanoemulsions in the present invention, is prepared by extracting from soybean or egg yolk (egg) and purifying it. Phospholipids having fatty acid chains having 12 to 24 carbon atoms, that is, phosphatidylcholine and phosphatidyl Ethanolamine, phosphatidylserine, phosphatidylglycerol, phosphatidylinositol, phosphatidic acid and other fatty acids produced by hydrolysis thereof. The fatty acid chain constituting the hydrophobic group of the lecithin is an unsaturated lecithin having an average of about 0 to 3 double bonds, and a mixture of 30 to 95% by weight of phosphatidylcholine may be used depending on the degree of purification. Since double bonds of unsaturated fatty acid chains of lecithin are easily oxidized by water or active oxygen, lecithin with saturated fatty acid chains prepared by hydrogenation can be used to increase the chemical stability of lecithin.

More specifically, the lecithin used in the present invention is a phospholipid extracted from soybean, and saturated lecithin having a phosphatidylcholine content of 30 to 95 wt% uses 0.2 to 5 wt% of the total nanoemulsion content, preferably 0.5 to 2 wt%. % use.

Nanoemulsion according to the present invention is an emulsion containing an oil in the inner phase and water in the outer phase, at least one oil having a low solubility in water and at least one bioactive active ingredient, preferably hair and scalp It can be produced by collecting the ingredients that are effective for the treatment. The active ingredient and oil may contain 2 to 30% by weight based on the total weight of the nanoemulsion, preferably 5 to 20% by weight based on the total weight of the nanoemulsion, but the type and content thereof are used for the purpose and the case. It can be adjusted accordingly.

As the physiologically active ingredient, a moisturizer for increasing the moisturizing effect on the scalp and the hair, a blood circulation promoter for strengthening the hair root, and a bactericidal and antimicrobial agent effective in scalp fungus, etc. Fat-soluble vitamins such as vitamin A, vitamin D, vitamin E and vitamin K, which may be contained in the particles of the nanoemulsion, water-soluble vitamins such as vitamin C, vitamin B and vitamin PP, panthenol and derivatives thereof, triclosan, and salicylic acid Can be used.

The oils used in the present invention are selected from oils of animal or vegetable origin, mineral oils, synthetic oils, silicone oils and mixtures thereof. More specifically caprylic / capric triglyceride, cetylethyl hexanoate, octyldodeces myristate, isopropyl myristate, isopropyl palmitate, butylene glycol dicaprylate / dicaprate, pentaerythryl tetraoctano Eight, octyl dodecanol, dicaprylyl carbonate, hydrogenated polydecene, dimethicone, cyclomethicone, phenyl trimethicone, squalane, phytosqualane, sunflower seed oil, meadowfoam seed oil, yoyoba oil, polyglyceryl- 2 triisostearate, diisosteayl malate, coconut oil, hexyl laurate, cetyl octanoate, trioctanoin, mineral oil, dialkyl malate and the like can be used.

The droplet size of the nanoemulsion according to the present invention is 50-800 nm in diameter, and the hydrogen ion concentration index (pH) is distributed between 5-7. In order to correct the pH, bases such as triethanolamine, calcium hydroxide and sodium hydroxide may be added in an amount of 0.01 to 0.1% by weight based on the total content.

In addition, a polymer thickener may be used for the emulsion stability of the nanoemulsion according to the present invention. Polymeric thickeners for the growth include polyacrylic acid, polymethacrylic acid, polyurethanes having a hydrophilic group of polyethylene glycol, polyvinyl alcohol, diblock and triblock copolymers in which polyethylene oxide and polypropylene oxide are combined with blocks. Natural polymers such as polymer and xanthan gum, hyaluronic acid, carrageenan gum, hydroxyethylcellulose, hydroxypropylmethylcellulose, carboxymethylcellulose, hydroxybutyl methylcellulose, methyl hydroxyethylcellulose, hydroxyethylcellulose, polyglutamic acid and chitosan Derivatives of polymers or natural polymers can be used.

The present invention also relates to a cosmetic composition for hair containing the nanoemulsion.

The cosmetic composition for hair according to the present invention preferably contains 0.0005 to 10.0% by weight, preferably 0.001 to 5% by weight, based on the total weight of the nanoemulsion. If the content of the nanoemulsion is less than 0.0005% by weight can not exert its efficacy properly, if the content of more than 10.0% by weight may cause formulation problems.

Looking at the shampoo composition containing a nanoemulsion according to the present invention, it contains a commonly used foaming agent, cleaning agent, conditioning agent, pH adjusting agent, pearling agent, preservatives, flavoring agent, viscosity adjusting agent and the like.

As the foaming agent and the detergent, ammonium lauryl sulfate (ALS), ammonium laureth sulfate (ALES), and sodium laureth sulfate (SLES), which are anionic detergents, may be used. It is preferable to use 1 to 30% by weight, preferably 5 to 20% by weight.

As a conditioning agent, dimethicone base, hydrogenated polydecene, cationic polymer, or the like may be used alone or in combination of two or more, and 0.1 to 10% by weight, preferably 0.5 to 5% by weight, based on the total weight of the composition. .

As the pH adjusting agent, sodium phosphate, disodium phosphate, citric acid, sodium citrate and the like can be used.

As the pulping agent, glycol distearate, glycol monostearate, fatty acids and the like can be used.

As antiseptics, methyl paraoxybenzoate, propyl paraoxybenzoate, sodium benzoate, methylchloroisothiazolinone, methylisothiazolinone, or the like may be used alone or in combination of two or more thereof.

As the viscosity adjusting agent, coamide amide, cocaramide DEA, sodium chloride, and the like, which are amide nonionic surfactants, can be used.

In addition, the conditioner composition containing the nanoemulsion includes preservatives, thickeners, viscosity regulators, pH adjusters, fragrances, etc. as tertiary amidoamines, quaternary ammonium compounds, high melting point compounds, silicone compounds, and optional components. It contains.

The quaternary ammonium compound which is the cationic surfactant includes alkyl (14-22) trimethyl ammonium chloride, dialkyl (14-22) dimethyl ammonium chloride, hydrogenated tallow alkyl trimethyl ammonium chloride, ditallow alkyl dimethyl ammonium chloride, and the like. The tertiary amidoamine is, for example, cocaamidopropyldimethylamine, stearamidopropyldimethylamine, beheniramidopropyldimethylamine, oleamidopropyldimethylamine, isostearamidopropyldimethylamine, or the like. have. The amines are preferably neutralized with acids such as L-glutamic acid, lactic acid, hydrochloric acid, malic acid, succinic acid, acetic acid, fumaric acid, citric acid and EDTA. These cationic surfactants may be used singly or in mixture of two or more thereof, using 1 to 30% by weight, preferably 5 to 20% by weight, based on the total weight of the total composition.

The high melting point compound is a compound consisting of fatty alcohol, fatty acid, fatty alcohol derivative, hydrocarbon, and mixtures thereof, and includes, for example, cetyl alcohol, stearyl alcohol, cetostearyl alcohol, and the like. It uses -10 weight%.

Silicone compounds used in the present invention include polyalkylsiloxane-based, polyarylsiloxane-based, polyalkylarylsiloxane-based, polyethersiloxane copolymers and mixtures thereof, cyclopolysiloxanes, and suitable alkyl amino-substituted compounds. 1 to 10% by weight is used.

The optional ingredients used in the present invention are well known to those skilled in the art as customary optional ingredients for maintaining basic physical properties and qualities. Specific examples include preservatives, thickeners, viscosity regulators, pH regulators, fragrances and the like.

The following is described in more detail with reference to the following embodiments of the present invention configured as described above. However, these examples are intended to illustrate the present invention, it is obvious to those skilled in the art that the scope of the present invention is not limited to these examples.

Hereinafter, the structure and effect of the hair shampoo composition containing the nanoemulsion containing the vitamin component according to the present invention will be described in more detail with reference to Examples and Test Examples. Compounding amount is shown by weight%.

Reference Example 1 Preparation of Nanoemulsion in which Tocopherol Acetate was Collected

As an active ingredient, a nanoemulsion was prepared in which tocopherol acetate, a derivative of vitamin E, was collected inside the particles.

1.5 g of phosphatidylcholine content (70-75%) extracted from soybean, 3 g of rapeseed sterol added with 5 mol of polyethylene glycol, 15 g of caprylic / capric triglyceride, ethanol 5 g, propylene glycol 5 g, methyl paraben 0.2 g, and 10 g of tocopherol acetate were mixed and warmed and dissolved at 65 ° C., and then mixed with 70 g of distilled water heated to 70 ° C. and emulsified at 5,000 rpm for 10 minutes with a homogenizer. The pre-emulsion made through emulsification was made into a homogeneous nanoemulsion through a high pressure emulsifier. At this time, the high pressure emulsification was operated at room temperature at 1,000 atm, and recirculated three times. The aqueous solution in which the prepared low-viscosity nanoemulsion was dispersed was dissolved in xanthan gum at 0.2% by weight to complete a nanoemulsion in which tocopherol acetate was collected.

[Examples 1 and 2 and Comparative Examples 1 and 2] Preparation of Shampoo

Table 1 summarizes the composition ratio of each component of the hair shampoo composition in the embodiment according to the present invention. The composition ratio of each composition is weight%.

Furtherance Comparative Example 1 Comparative Example 2 Example 1 Example 2 Ammonium Laures Sulfate * 40 40 40 40 Glycol distearate 2.0 2.0 2.0 2.0 Cetyl alcohol 0.8 0.8 0.8 0.8 Cocamide MEA 1.0 1.0 1.0 1.0 Ammonium Lauryl Sulfate ** 30 30 30 30 Cationic Polymer *** 0.3 0.3 0.3 0.3 Hydrocarbon **** 0.5 0.5 0.5 0.5 silicon 2.0 2.0 2.0 2.0 Sodium chloride 1.2 1.2 1.2 1.2 Disodium EDTA 0.05 0.05 0.05 0.05 Spices 0.8 0.8 0.8 0.8 antiseptic 0.03 0.03 0.03 0.03 Citric acid 0.1 0.1 0.1 0.1 Panthenol 0.0 0.2 0.2 0.2 Tocopherol Acetate 0.0 0.2 0.0 0.0 Tocopherol acetate nanoemulsion (contains 10% tocopherol acetate) 0.0 0.0 0.2 2.0 Dilution water to 100 to 100 to 100 to 100

*: Ammonium laures sulfate (25%), **: ammonium lauryl sulfate (25%),

***: Polyquaternium-10, ****: Hydrogenated Polydecene

To prepare a hair shampoo composition containing a nanoemulsion containing tocopherol acetate as an active ingredient, a shampoo was prepared according to the composition of Table 1 and a conventional shampoo preparation method.

Examples 3 and 4 and Comparative Examples 3 and 4 Preparation of Conditioner

Table 2 summarizes the composition ratio of each component of the hair conditioner composition in an embodiment of the present invention. The composition ratio of each composition is weight%.

Furtherance Comparative Example 3 Comparative Example 4 Example 3 Example 4 Stearamidopropyldimethylamine 2 2 2 2 Citric acid 0.4 0.4 0.4 0.4 Cetyl alcohol 2 2 2 2 Stearyl alcohol 4 4 4 4 silicon 4 4 4 4 Spices 0.7 0.7 0.7 0.7 antiseptic 0.03 0.03 0.03 0.03 Panthenol 0.0 0.2 0.2 0.2 Tocopherol Acetate 0.0 0.2 0.0 0.0 Tocopherol acetate nanoemulsion (contains 10% tocopherol acetate) 0.0 0.0 0.2 2.0 Dilution water to 100 to 100 to 100 to 100

Conditioners were prepared according to the compositions and conventional methods of Table 1 above to prepare a hair conditioner composition containing a nanoemulsion containing tocopherol acetate as an active ingredient.

Test Example 1 Measurement of Particle Droplet Size of Nanoemulsion by Dynamic Light Scattering

In order to measure the average particle size of the nanoemulsion prepared in Reference Example 1 was measured by dynamic light scattering (Dynamic light scattering, instrument model Zetasizer 3000HS, Malvern, UK), the fall angle is fixed at 90 degrees, the temperature is Measured while maintaining at 25 degrees. The average particle diameter is the average particle diameter calculated from the Stokes-Einstein equation and the size distribution of the emulsion droplets was calculated according to the CONTIN method. The results are shown in FIG.

As shown in Figure 1, it was found that the average particle size of the tocopherol acetate-containing nanoemulsion used in the present invention is 70 ~ 100nm having the highest skin absorption.

Test Example 2 Measurement of Skin Absorption Rate

The skin absorption test was performed using the hair cosmetic composition prepared in Examples 1-4 and Comparative Examples 1-4. Guinea pigs (strain IAF / HA-hrBP) of 8 weeks of age were used for skin absorption experiments. Hairy skin of guinea pigs was cut out and mounted in Frans-type diffusion cells (lab fine instruments). 5 ml of distilled water was placed in a receptor vessel, which is a Franz type permeable cell vessel. The permeation cell was mixed and dispersed at 6000 rpm while maintaining 32 ° C., and 300 µl of the solution prepared in Examples 1 to 4 and Comparative Examples 1 to 4 was placed in a donor container and maintained for 3 minutes. After adding 1 ml of distilled water and maintaining the mixture for 1 minute, a sample and a mixture of distilled water were prepared, and this process was performed for 20 times.

The area of skin where absorption diffusion occurs was 0.64cm2. After absorption diffusion of nanoemulsion, the skin surface is washed with 1 ml of distilled water, and tip type homogenizer is used in 6 ml of ethanol (Polytron PT2100, Switzerland). After the skin having the active ingredient absorbed and diffused was changed, the extract was filtered using a 0.45 μm nylon filtration membrane, and the content was measured by high pressure liquid chromatography.

In Figure 2, Example 2 (D) containing 2.0% by weight of tocopherol acetate nanoemulsion showed the best skin absorption, the absorption of the nanoemulsion contained in the hair cosmetic formulation is more promoted by the surfactant and the like Showed. However, in the case of tocopherol acetate which is not contained in the nanoemulsion, the skin absorption amount was lower than that of Example 2, and it was confirmed that the nanoemulsion promoted the skin absorption of tocopherol acetate.

In Figure 3, Example 4 (D) containing 2.0 wt% of tocopherol acetate nanoemulsion showed the best skin absorption, which indicates that the absorption of the nanoemulsion contained in the hair conditioner formulation is more promoted by the surfactant or the like. Showed. However, in the case of tocopherol acetate which is not contained in the nanoemulsion, it was confirmed that the nanoemulsion promoted the skin absorption of tocopherol acetate as shown in FIG.

Test Example 3 Measurement of Hair Tensile Strength

Hair tensile strength of the shampoos and conditioners prepared in Examples 1 to 4 and Comparative Examples 1 to 4 were measured. First, normal hair tress was prepared. 5 g of each conditioner was applied to the hair tress and then washed 10 times in constant flowing ionized water. The washed hair tress was left to stand at least 24hr under constant temperature, constant humidity (relative humidity: 40%, temperature: 25 ° C) and dried sufficiently. Hairs with a thickness of 80 ± 10 μm were collected from a fully dried tress. Using Instron (model: 4443), the collected hair was measured for tensile strength and the breaking point of the hair was recorded. After experimenting with 8 to 10 hairs, the average breaking point was used as data, and the results are shown in FIGS. 4 and 5.

As shown in FIGS. 4 and 5, both the shampoo and the conditioner containing tocopherol acetate showed an increased breaking point. The nanoemulsion of tocopherol acetate, together with the panthenol component, enhances the hair's moisturizing effect. It was found that the absorption of the nanoemulsion contained in the shampoo and conditioner formulation is promoted to impart this moisturizing synergy.

Test Example 4 Results of Use Quality Tests by Composition

A panel composed of 50 women aged 20 to 30 years was used for 2 weeks for the products manufactured in Examples 1 to 4 and Comparative Examples 1 to 4, and the questionnaire items were answered on a 7-point scale. The following results were obtained by evaluating the quality of use through the simple monadic test.

Survey Item Comparative Example 1 Comparative Example 2 Example 1 Example 2 1. Air bubbles are good and air bubbles feel good 5.6 5.7 5.4 5.5 2. Feels good when rinsing and fingers pass well 4.8 5.0 5.0 4.9 3. Combing is easy and soft during semi-drying 5.5 5.6 5.5 5.6 4. Hair care is easy and soft after drying 5.2 5.4 5.2 5.4 5. Moisturizes hair after drying 4.6 5.2 4.9 5.5 6. The gloss of hair is felt after drying 3.8 4.2 4.0 4.5

Survey Item Comparative Example 3 Comparative Example 4 Example 3 Example 4 1. Spreads well and has good nutrition when applied 5.4 5.6 5.4 5.6 2. Feels good when rinsing and fingers pass well 6.2 6.4 6.2 6.5 3. Combing is easy and soft during semi-drying 5.7 5.8 5.7 5.8 4. Hair care is easy and soft after drying 5.6 5.8 5.6 5.8 5. Moisturizes hair after drying 5.2 5.8 5.5 5.9 6. The gloss of hair is felt after drying 4.8 5.2 5.0 5.5

As described above, it was found that the cosmetic composition for hair according to the present invention had an effect equal to or greater than that of the comparative example even in the feeling of use.

The cosmetic composition for hair produced by the present invention enhances the absorption of the active ingredient in the hair or scalp by containing a certain amount of the nanoemulsion in the formulation containing the active ingredient which improves the scalp and the health of the hair in the nanoparticles of 50 to 500 nm. To improve the health of the hair.

Claims (6)

A cosmetic composition for hair containing saturated lecithin having a phosphatidylcholine content of 30 to 95% by weight and a nanoemulsion in which a bioactive active ingredient is collected. The hair cosmetic composition of claim 1, wherein the nanoemulsion is contained in an amount of 0.0005 to 10.0% by weight based on the total weight of the composition. The cosmetic composition for hair according to claim 1, wherein the nanoemulsion has a particle diameter of 50 to 500 nm. The hair cosmetic composition according to claim 1, wherein the composition has a shampoo formulation further containing a foaming agent, a cleaning agent, a conditioning agent, a pH adjusting agent, a pearling agent, a preservative, a flavoring agent, and a viscosity adjusting agent. The composition of claim 1, wherein the composition is a conditioner formulation further containing a tertiary amidoamine and a quaternary ammonium compound, a high melting point compound, a silicone compound, a preservative, a thickener, a viscosity adjuster, a pH adjuster, and a fragrance as a cationic surfactant. Cosmetic composition for hair, characterized in that. According to claim 1, wherein the physiologically active active ingredient is composed of a water-soluble vitamin such as vitamin A, vitamin D, vitamin E, vitamin K, vitamin C, vitamin B, vitamin PP, panthenol and derivatives thereof, triclosan and salicylic acid Cosmetic composition for hair, characterized in that selected from the group.