KR20040007034A - Germicidal Fertillizing Aqua-solution Comprising Colloidal Silver and Minor Species - Google Patents

Abstract

PURPOSE: Provided is a liquid trace element fertilizer for improving sterilization of insects and harmful microbes, and growth condition for crops by containing colloidal silver particles in trace element fertilizer composition. CONSTITUTION: The composition of sterilizing trace element fertilizer solution contains the components of: 10-1000ppm of colloidal silver particles less than 20nm in size; at least one trace element source selected from B-source more than 500ppm based on B2O3, Cu-source more than 500ppm based on Cu, Fe-source more than 1000ppm based on Fe, Mn-source more than 1000ppm based on MnO, Mo-source more than 5ppm based on Mo, Zn-source more than 500ppm based on Zn; and optionally at least one macro nutrient element selected from N, P, K, S, Ca, Mg and Cl. The sources of trace elements are water soluble, and B-source is sodium borate or boric acid, Cu-source is copper sulfate, F-source is ferric citrate, iron sulfate or Fe-EDTA, Mn-source is manganese sulfate, Mo-source is sodium molybdate, and Zn-source is zinc sulfate or Zn-EDTA. The prepared liquid fertilizer sterilizes virus, mold and bacteria.

Description

Germicidal Fertillizing Aqua-solution Comprising Colloidal Silver and Minor Species

The present invention relates to a bactericidal microurea fertilizer comprising silver colloidal particles. Silver powder has long been commercially available in the form of silver. The antibacterial and bactericidal effects of silver are known empirically and silver products manufactured by various methods without specific and clear experimental data have been used as folk remedies for treating a wide range of human diseases. The field of disease treatment is diverse, and it is used as a concept of panacea for almost all kinds of bacterial diseases and diseases caused by viruses such as colds, which are not solved in modern medicine, as well as cancers that still have no perfect solution. This widespread use of silver products tends to be used as alternative medicine concepts as the problem of resistance to chemically synthesized antibiotics is seriously raised and the cost of manufacturing silver products drops sharply. However, responsible authorities, for example, the US FDA, do not recognize the product as a treatment for human disease. In case of insufficient effect or prolonged overuse due to various manufacturing methods and quality problems that have not been approved, Argyria symptom with silver deposit on skin and blue color has been reported. Because

There are many ways to apply silver products, 1) using powder form, 2) chemically producing silver ion water, 3) dispersing powder in water, 4) electrochemically decomposing There is a method of making silver ionized water.

Except for the direct drinking of silver, patents and utility models have been disclosed in which silver is plated on a substrate using antiseptic properties of silver particles to provide antibacterial and bactericidal properties. Korean Patent Publication No. 1020000024652 (published date; 2000/05/06) discloses an agricultural piping material manufactured by plating silver on a plastic substrate, and Korean Patent Publication No. 20020011310 (published date; 2002/02/08) includes silver nitrate. Techniques for impregnating and fixing antimicrobial properties to fibers are disclosed, and Korean Patent Publication No. 2002008375 (published date; 2001/01/30) describes a spray agent containing colloidal silver. This prior art utilizes the general antimicrobial properties of silver.

On the other hand, in order for plants to grow normally, hydrogen, oxygen and carbon obtained from water or air, as well as large elements such as nitrogen, potassium, calcium, magnesium, phosphorus and sulfur, as well as chlorine, boron, iron, manganese, zinc, copper and molybdenum Trace element of is required. These microelements include microurea complex fertilizers (also known as "four kinds of microurea complex fertilizers") containing a single fertilizer and two or more trace elements above a prescribed value, such as boric acid fertilizer, borax and zinc sulfate fertilizer. Trace urea fertilizers have much less requirements than large elements, but are essential for the growth of plants.

In the cultivation of crops, there is a need for a natural-friendly farming method that reduces the residual toxicity of crops and does not harm nature by cultivating no pesticides or low pesticides. The present inventors can identify the physical and chemical properties of silver particles and spread the microbicidal microurea fertilizer containing silver colloidal particles in combination with the microurea fertilizer element to the crops to significantly improve the growth conditions of the crops as well as the bactericidal effect of plant pests. The present invention has been completed and the present invention has been completed. An object of the present invention is to provide a bactericidal microelement fertilizer that can improve the growth conditions of crops with the sterilizing effect of pests while helping the environment-friendly farming without the problem of residual toxicity.

The present invention provides a water-soluble boron source of 500 ppm or more on the basis of B ₂ O ₃ , a water-soluble copper source of 500 ppm or more on the basis of Cu, a water-soluble iron source of 1000 ppm or more on the basis of Fe, a water-soluble manganese source of 1000 ppm or more on the basis of MnO, and a water-soluble molybdenum source of 5 ppm or more on the basis of Mo and Provided is a bactericidal concentrated urea fertilizer concentrated aqueous solution composition comprising at least one trace element source selected from the group consisting of 500 ppm or more of water-soluble zinc source and 10-1000 ppm of silver-closed particles having a particle size of 20 nm or less.

Surfactants may be further included to improve the dispersibility of the silver colloid particles and to increase the scattering effect on the crops. Surfactants used to improve the susceptibility of silver particles include, for example, polyethoxylated alcohols, polyethoxylated alkylphenols, polyethoxylated sorbitan fatty acid esters, dialkylsulfosuccinates, alkyl sulfates, Alkylbenzene sulfonates, organosilicones, N, N-dialkyltaurates, lignin sulfonates, naphthalene sulfonates, formaldehyde concentrates, polycarboxylates and the like.

The boron source is BO ₃ ^3- or B ₄ O ₇ ^2- , for example obtained by dissolving sodium borate or boric acid. The copper source is for example copper sulfate, the iron source is for example iron citrate, ferrous sulfate or chelated iron and the chelated iron is EDTA-Fe, for example. However, ferric chloride is not preferred as an iron source. Chlorine combines with silver particles to eliminate the sterilization properties of the silver particles (poison) and to reduce the dispersibility by removing the charge of the silver particles significantly reduces the sterilization effect. The manganese source is for example EDTA-Mn or manganese sulfate and the molybdenum source is for example ammonium molybdate or soda molybdate and the zinc source is for example zinc sulfate or chelated zinc of EDTA-Zn. If necessary, it may further include one or more multi-element selected from the group consisting of nitrogen, phosphorus, kali, sulfur, calcium and magnesium in an aqueous solution.

Such a bactericidal microelement fertilizer concentrated aqueous solution composition is properly diluted and used as necessary to actually apply to the crop. Dilution by 500 times is selected from the group consisting of 0.1 ppm or more of water-soluble boron source, 0.1 ppm or more of water-soluble copper source, 0.2 ppm or more of water-soluble iron source, 0.2 ppm or more of water-soluble manganese source, 0.001 ppm or more of water-soluble molybdenum source and 0.1 ppm or more of water-soluble zinc source A disinfectant microurea fertilizer aqueous solution composition comprising at least one trace element source and 0.1-50 ppm of dispersed silver clad particles having a particle size of 20 nm or less. Such a disinfectant microurea fertilizer aqueous solution composition may be directly distributed on the side or stem of the plant, or in some cases, in the adjacent soil. Direct spraying on plants can have a good bactericidal effect. It is particularly preferable that the trace elements are directly dispersed in plants in the case of manganese or zinc.

It is acceptable that some of the silver colloidal particles be silver ions. Most important to the present invention are the size and dispersibility of the particles. The particle size is less than 20 nm. Preferably the particle size is 10 nm or less. Although particles larger than 20 nm are not allowed, the control effect is significantly lower than the silver content. If the particle size is small and the dispersibility is not ions, a large sterilization effect can be obtained with a small amount of silver. It is desirable to reduce the size of the particles, but there are limitations in the production method. The smaller the particle size, the better the dispersibility. This is because silver particles are thought to act on phytopathogens at their interface and prevent the metabolism of pathogens. The positive charge of the particles favors dispersibility but is not a requirement.

The silver particles of the present invention may include ionic silver particles prepared by a chemical method by diluting silver acetate or silver nitrate to water and diluting them to an appropriate range, or by volatilizing the acetic acid component or nitric acid component. These ionic silver particles are excellent in dispersibility and poor sterilization by themselves but are absorbed better than larger particles in plants. Silver ions particles absorbed into plants are believed to enhance the growth conditions of plants by giving them resistance to persistent pests.

Silver particles suitable for the present invention can be produced by an electrolysis method. In the electrolysis method, a direct current having a relatively low voltage (less than 50 V) or an alternating current having a relatively high voltage (greater than 100 V) may be produced by energizing water purified to distilled water. Adding an appropriate amount of silver nitrate salt has the advantage of obtaining a silver colloid containing ionic particles and accelerating the reaction at an early stage.

Another method of preparing the silver particles of the present invention may be prepared by dispersing a silver powder having a particle size of 20 nm or less prepared by a method of arc discharge with a silver electrode in water.

Phytopathogens that can be applied to the bactericidal effect of the bactericidal microelement fertilizer of the present invention is a wide range. It is useful for bacterial and viral pathogens in plants. Particularly useful for fungal pathogens, it is effective against fungi (oomycetes) and true fungi. In fungi, for example, it is effective against rots of the fungal pathogens (Peronosporales) and fungi of the Pythiaceae family and the fungal pathogens (Peronosporaceae). For example, the Pythium genus and the Phytophthora genus also have significant effects on the rot family. The genus Phytophthora causes late blight, depending on the host plant: P. infestans P. cactorum, P. cambivora, P. cinnammori, P. citrophthora, P. frgariae, P. palmivora, P. syringae P. nicotianae, P. parasitica, Fungi of P. drechsleri, P. melonis species. Some species of the phytophthora invade one or two types of host plants, but the range of host invasion is quite wide. For example, P. infestans cause potato and tomato blight, P. capsici causes pepper, cucumber, melon, watermelon, pumpkin, tomato, eggplant plague, P. nicotianae causes potato, eggplant strawberry, leek plague, and P. cactorum Apple, ginseng, and strawberry blight, P. parasitica causes downy blight, tobacco blight, P. drechsleri causes watermelon, melon, lettuce, cabbage, spinach plague, and P. melonis causes watermelon, melon, cucumber blight The silver particle colloid of the present invention has a particularly remarkable effect on such late blight.

In soothing fungi, for example, powdery mildew, rice blasting, boat rice disease; Basidiomycetes, for example, grain rust and Laa-tononia disease was found to have an effective control. In particular, there was an excellent control effect with respect to rice blast.

The aqueous disinfectant microurea fertilizer solution of the present invention can obtain excellent growth effects as well as control of plant diseases by being dispersed more than once in plants.

Hereinafter, the present invention will be described in detail with reference to Examples. These examples are intended to illustrate the invention and should not be construed as limiting the scope of the invention.

Example 1

In order to increase the silver colloid concentration, the zinc sulfate + manganese sulfate aqueous solution was diluted without directly diluting the concentrated aqueous solution of the present invention, and a separate silver colloidal aqueous solution was added to give 2 ppm of zinc sulfate, 2 ppm of manganese sulfate, and the particle size of 20 nm or less. 200 ml of an aqueous solution of the present invention was prepared with 5 ppm silver colloid and 50 ppm surfactant Tween 20 (registered trademark of ICI America as polyethoxylated sorbitan laurate). The growth and control effects were tested for the following seven types of plant diseases.

Aqueous treatment is rotated by placing two sets of potted plants inoculated with each subject bottle inoculated or vaccinated host plants on a turntable. One tank was sprayed with a spray gun (1 kg / cm ² ) to evenly attach the aqueous solution to the entire plant. The other bath is sprayed with water containing only 50 ppm of surfactant. After the test plants were grown in a greenhouse for 1 day, the pathogens were inoculated as follows and the lesions and growth conditions (leaf width and leaf length) were examined.

Plant diseases: The plant diseases used in the experiments for the in vivo bactericidal activity test of the bactericidal microurea fertilizer solution were rice blast (RCB), rice sheath blight (RSB) and tomato gray mold. Bottles (tomato gray mold, TGM), tomato late blight (TLB), red pepper blight (RPB), wheat leaf rust (WLR), and barley powdery mildew (BPM) 7 kinds

Pathogen inoculation and the development of plant diseases:

Rice blast was inoculated in rice bran agar medium (Rice Polish 20g, Dextrose 10g, Agar 15g, distilled water 1L) strain Magnaporthe grisea KJ201 strain was incubated for 2 weeks in a 25 ℃ incubator. Pathogen-grown media was rubbed with a Rubber Polishman to remove the media hyphae, and spores were formed on a fluorescent lamp-turned shelf (25-28 ° C.) for 48 hours. The inoculation was performed by condensing spores using sterilized distilled water to make a spore suspension (1 × 10 ⁶ conidia / ml) at a certain concentration, and then spraying it in Nakdong rice (2 ~ 3 leaf). After inoculated rice and non-inoculated rice were kept in a dark place for 24 hours in a dark state, the relative humidity of more than 80% and the temperature of 26 ℃ were left in a humid chamber for 5 days and the leaf width and leaf length were measured. The lesion area was investigated.

Rice leaf blight (RSB) was sterilized by placing an appropriate amount of bran in a 1L culture bottle. Inoculated with the pathogen Rhizoctonia solani AG-1 strain in sterile medium and incubated in a 25 ℃ incubator for 7 days. The bottle inoculation was inoculated by finely crushing the cultured mycelium masses and pouring them into pots grown with 3-4 leaf Nakdong rice. Inoculated rice and non-inoculated rice were incubated for 7 days in a separate wet room (25 ℃). The leaf width and leaf length of the leaves were measured, and the pathologic area rate of the diseased leaves was investigated.

Tomato gray mold disease (TGM) is inoculated with the pathogen Botrytis cinerea in potato agar medium for 7 days at 25 ℃ thermostat (cancer), and then incubated for 12 days a day by crossing the light cancer for 7 days to form spores I was. The bottle was inoculated with spores formed in the medium by Potato dextrose broth, and the spore concentration was 5 × 10 ⁵ conidia / ml using a hemocytometer, and then sprayed onto tomato seedlings (3 leaf phase). The inoculated tomato seedlings and the non-inoculated seedlings were placed in an isolated 20 ° C. wethouse (95% relative humidity) for 3 days, and then the leaf width and leaf length of the leaves were measured, and the lesion area ratio was determined from the lesions formed on the leaves. Investigated.

Tomato Blight (TLB) was inoculated with the pathogen Phytophthora infestans PIT strain in oatmeal agar medium for 7 days in a 20 ° C thermostat (cancer), followed by irradiation for 16 hours a day, followed by another 7 days. To form a zygote sac. Germ inoculation was harvested by adding sterilized distilled water, and spore concentration was measured with a hemocytometer under an optical microscope to make a spore suspension of 5 × 10 ⁵ sporangia / ml. Tomato seedlings (two to three leafy days) were sprayed. Inoculated tomato seedlings and non-inoculated seedlings are wetted for 4 days in a 20 ° C isolated room. After wet treatment, leaf width and leaf length of leaves were measured and lesion area ratio was investigated.

Red pepper plague (RPB) was inoculated with the pathogen Phytophthora capsici CY6225 in oatmeal agar medium and incubated in a 25 ° C thermostat for 7 days, followed by removing aerial hyphae with a brush and turning on a fluorescent lamp (25-28 ° C). Spores were formed for 24 hours. The spores formed were harvested with sterile water, and after distilling the strainer, the spore concentration was examined by using a hemocytometer under an optical microscope to make a spore suspension of 1 × 10 ⁵ zoospores / ml and sprayed the red pepper seedlings. Pepper and inoculated pepper inoculated with the pathogen are wet-treated in a separate, 25 ° C wet room for 1 day. Take out the plants and grow them in the greenhouse. Leaf width and leaf length of leaves were measured and lesions were examined.

Wheat red rust (WLR) is a pathogen, Puccinia recondita, is a parasitic bacterium. Therefore, the spores formed in wheat seedlings were used as inoculum while the plants were passaged directly to plants. To investigate the efficacy of the strain, five seed grains (variety: light) were seeded in disposable pots (diameter: 6.5 cm) and spore suspension (spore 0.67 g / L) was added to the seedlings grown in greenhouse for 8 days. Spray inoculation. Inoculated wheat seedlings and non-inoculated seedlings were wet-treated for one day in an isolated 20 ° C. chamber and then transferred to a 20 ° C. constant temperature and humidity chamber with a relative humidity of 70%. Seven days after inoculation, the leaf width and leaf length of the leaves were measured and the lesion area ratio was investigated.

Barley powdery mildew (BPM) is a pathogen Erysiphe graminis f. sp. Since hordel is a biomolecular bacterium, spores formed in barley were used as inoculum during subculture to barley seedlings in the laboratory. Pharmacokinetic investigation was inoculated by spraying barley powdery spores on the first seedling barley seedlings grown in a greenhouse for 8 days by sowing five barley seeds (variety: copper barley) in a disposable pot (diameter: 6.5 cm). Inoculated barley seedlings and non-inoculated seedlings are kept in a constant temperature and humidity room at 20-23 ° C. and 50% relative humidity for 7 days. Leaf width and leaf length of leaves were measured and lesion area ratio was investigated.

(Results and Discussion)

The bactericidal trace urea fertilizer solution tested showed about 70-95% control against tomato and pepper late blight, and had little control against the remaining five pests. The bactericidal trace urea fertilizer solution was thought to be effective against most of the late blight caused by Phytophthora genus.

Table 1.Prevention and Growth Effect of Disinfectant Microurea Fertilizer Aqueous Solution

(Inoculation is 1 day after aqueous solution treatment)

division RCB RSB TGM WLR TLB RPB BPM No vaccination Inventive solution Sickness 100 100 100 100 49 18 100 0 Growth effect 73 80 71 81 89 95 67 112 Only surfactant (Comparative solution) Sickness 100 100 100 100 100 100 100 0 Growth effect 52 61 48 64 60 57 49 100

RCB: Rice Blast, RSB: Rice Leaf Blight, TGM: Tomato Blight,

TLB: Tomato plague, RPB: Pepper plague, WLR: Wheat rust, BPM: Barley flour

Growth effect: Calculates the product of leaf width and leaf length and displays the percentage (%) for treatment of non-inoculated comparative solution (containing only surfactant)

Example 2

Control and Growth Effects of Six Different Diseases after Treatment with Different Number of Treatments

In the same manner as in Example 1, 2 ppm of zinc sulfate, 2 ppm of manganese sulfate, 5 ppm of silver colloid having a particle size of 20 nmd or less, 80 ppm or more, and 50 ppm of surfactant Tween 20 (registered trademark of ICI America as polyethoxylated sorbitan laurate) 200 ml of an aqueous solution was prepared. The growth and control effects of the following six plant diseases were tested in the same manner as in Example 1. One tank was sprayed with an aqueous solution of the present invention to evenly attach the aqueous solution to the entire plant with a spray gun. The other bath is sprayed with water with only 50 ppm of surfactant added to the water for comparison.

In this experiment, several germicidal microurea fertilizers containing silver colloidal particles were used to test plant disease control and growth effects. After spraying the bactericidal microurea fertilizer aqueous solution twice a day (morning and afternoon) from day 1 to day 3, 6 pathogens were inoculated and developed to investigate the growth and control effects. Plants treated with an aqueous solution were grown in a greenhouse for 1 day, and then inoculated with pathogens, and the lesions, leaf width, and leaf length were examined.

Plant diseases: The plant diseases used in the experiments for the in vivo bactericidal activity test of the bactericidal microurea fertilizer solution were rice blast (RCB), rice sheath blight (RSB) and tomato gray mold. 6 types including bottle (tomato gray mold, TGM), tomato late blight (TLB), wheat leaf rust (WLR) and barley powdery mildew (BPM)

Preparation and Treatment of Aqueous Solution: Aqueous solution was cultivated in a 4potsTlr greenhouse for each target bottle, and sprayed to distribute the aqueous solution evenly to the whole plant with a hand sprayer, and inoculated with the pathogen 1 day after the final aqueous solution treatment.

Pathogen inoculation and plant disease onset: The same as in Example 1.

( Results and Discussion)

In this experiment, the bactericidal microurea fertilizer solution was sprayed twice a day (morning and afternoon) from day 1 to day 3, and then 6 pathogens were inoculated and developed to investigate the control effect. As a result, as the frequency of treatment of the bactericidal microurea fertilizer solution per week increased, the control effect was increased for all six plant diseases (Table 2). In the first experiment, it showed excellent control effect not only in tomato blight, but also in rice blast and wheat rust. In particular, rice blasting showed high control effect even twice a day. In addition, about 50% of barley powdery disease and tomato ash mold were found to show bactericidal activity.

In addition, when the aqueous solution of the present invention is used, the growth effect of about 2-3 times can be confirmed at the time of inoculation of the germ compared to the agitation solution.

Table 2. Effect of Disinfectant Trace Urea Fertilizer Solution on Six Plant Diseases

(Indicated by the area area)

division RCB RSB TGM TLB WLR BPM No vaccination Twice a day Inventive solution Sickness 5 65 70 10 15 45 0 Growth effect 98 75 69 95 96 87 115 Comparative amount Sickness 100 100 100 100 100 100 0 Growth effect 41 39 33 47 35 36 100 4 times a day Inventive solution Sickness 0 62 69 8 12 40 0 Growth effect 102 80 74 101 99 92 123 Comparative amount Sickness 100 100 100 100 100 100 0 Growth effect 30 45 40 36 29 43 100 6 times 3 days Inventive solution Sickness 0 58 61 5 10 38 0 Growth effect 115 83 81 113 109 105 121 Comparative amount Sickness 100 100 100 100 100 100 0 Growth effect 37 33 28 45 36 32 100

^a RCB: rice blast, RSB: rice leaf blight, TGM: tomato gray mold,

TLB: Tomato blight, WLR: Wheat rust, BPM: Barley powdery mildew

^b lesion area percentage (%) = 100-controlled value (%)

Growth effect: Comparing solution of vaccinated tank by calculating the product of leaf width and leaf length

Display percentage (%) for treatment (contains only surfactant)

Example 3

Therapeutic Effect on Three Plant Diseases by Multiple Treatments

(Experimental method)

Plant diseases: The plant pathogens used in the experiments for the in vivo treatment effect of the bactericidal microurea fertilizer solution were rice blast (RCB), wheat leaf rust (WLR), and barley flour (barley). powdery mildew, BPM).

Preparation and Treatment of Aqueous Solution: An aqueous solution preparation prepared 200 ml of an aqueous solution in the same manner as in Example 1. Aqueous treatment was inoculated with 6 pathogens to each plant grown in the greenhouse, and plants inoculated with five plant diseases except powdery mildew were wet-treated in a wet room for one day, and plants inoculated with powdery mildew were placed on the growth shelf in a constant temperature and humidity room. After inducing pathogens, treatment was done once a morning, afternoon twice a day, once a day, two days, and three days a week to treat three plant diseases. ) Was investigated. Same as the above preventive effect experiment, but the number of treatments was different. Rice leaf blight, tomato gray mold, and tomato late blight were excluded from the experiment due to the characteristics of the disease.

Pathogen inoculation and plant disease outbreak: The same as the preventive effect experiment.

(Results and Discussion)

After inoculating pathogens in rice, barley, and wheat, the treatment effect of bactericidal trace urea fertilizer solution was repeatedly treated after 1 day of treatment, and there was no cure effect for rice blast and barley flour disease, but wheat rust was an aqueous solution. The treatment effect increased as the number of treatments was increased (Table 3). Therefore, it is thought that the treatment of wheat red rust can be treated by treating the disinfectant microurea fertilizer solution in the early stage even if the disease occurred.

Table 3. Therapeutic Effect of Bactericidal Microurea Fertilizer

division RCB WLR BPM 1 day per week Aqueous solution of the present invention 7 2 0 Comparative amount 0 0 0 2 days per week Aqueous solution of the present invention 0 10 0 Comparative amount 0 0 0 3 days per week Aqueous solution of the present invention 5 50 0 Comparative amount 0 0 0

It was confirmed that the bactericidal microurea fertilizer aqueous solution of the present invention has a prophylactic and therapeutic effect against various plant pathogens while maintaining the growth effect of the plant. In particular, excellent preventive effects have been demonstrated against late blight, which is known to be relatively difficult to control. It also showed excellent effects against rice blasts. When used as an aqueous solution of the disinfectant microurea fertilizer aqueous solution of the present invention does not require a separate hand and there is almost no problem of residual toxicity. The aqueous disinfectant microurea fertilizer solution of the present invention is not only economically feasible but also economical because it is easy to use for process storage.

Claims (9)

500 ppm or more water-soluble boron source based on B ₂ O ₃ , 500 ppm or more water-soluble copper source based on Cu, 1000 ppm or more water-soluble iron source based on Fe, 1000 ppm or more water-soluble manganese source based on MnO, 5 ppm or more water-soluble molybdenum source based on Mo, and Zn standard A concentrated aqueous solution of a bactericidal trace urea fertilizer comprising at least one trace element source selected from the group consisting of 500 ppm or more of water-soluble zinc and 10 to 1000 ppm of silver-clade particles having a particle size of 20 nm or less. The method of claim 1, further comprising a surfactant bactericidal microelement fertilizer concentrated aqueous solution composition. 3. The method of claim 1 or 2, wherein the boron source is sodium borate or boric acid, the copper source is copper sulfate, the iron source is iron citrate, ferrous sulfate or iron chelate, and the manganese source is manganese sulfate and the molybdenum A sterilized microurea fertilizer concentrated aqueous solution composition wherein the source is ammonium molybdate or soda molybdate and the zinc source is zinc sulfate or chelated zinc. 500 ppm or more water-soluble boron source based on B ₂ O ₃ , 500 ppm or more water-soluble copper source based on Cu, 1000 ppm or more water-soluble iron source based on Fe, 1000 ppm or more water-soluble manganese source based on MnO, 5 ppm or more water-soluble molybdenum source based on Mo, and Zn standard At least one trace element source selected from the group consisting of 500 ppm or more water-soluble zinc sources; 10 to 1000 ppm of silver-clad particles having a particle size of 20 nm or less; and one or more multi-elements selected from the group consisting of nitrogen, phosphorus, kali, sulfur, calcium, magnesium and chlorine are further contained in an aqueous solution. Aqueous solution composition. At least one trace element source selected from the group consisting of at least 0.1 ppm water-soluble boron source, at least 0.1 ppm water-soluble copper source, at least 0.2 ppm water-soluble iron source, at least 0.2 ppm water-soluble manganese source, at least 0.001 ppm water-soluble molybdenum source, and at least 0.1 ppm water-soluble zinc source And 0.1-50 ppm of dispersed silver clad particles having a particle size of 20 nm or less. 6. The method of claim 5, wherein the boron source is sodium borate or boric acid, the copper source is copper sulfate, the iron source is iron citrate, ferrous sulfate, or chelate iron, the manganese source is manganese sulfate, and the molybdenum source is molybdate A sterilizing microurea fertilizer aqueous solution composition comprising ammonium or soda molybdate and the zinc source is zinc sulfate or zinc chelating zinc. 7. The aqueous disinfectant microurea fertilizer solution composition of claim 6, wherein a part of the silver colloidal particles is silver ions. 8. The aqueous solution of the bactericidal microurea fertilizer according to claim 7, wherein the plant pathogen to be sterilized is a virus, a bacterium or a fungus. According to claim 8, wherein the plant pathogen is Phytophthora genus pathogens, rust pathogens or rice fever pathogens bactericidal microurea fertilizer aqueous solution composition.