KR20030068696A - 스탓3 (stat3) 분자 활성화에 의한 줄기세포의 생체내이식생착효율 증가 - Google Patents

스탓3 (stat3) 분자 활성화에 의한 줄기세포의 생체내이식생착효율 증가 Download PDF

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KR20030068696A
KR20030068696A KR1020020008272A KR20020008272A KR20030068696A KR 20030068696 A KR20030068696 A KR 20030068696A KR 1020020008272 A KR1020020008272 A KR 1020020008272A KR 20020008272 A KR20020008272 A KR 20020008272A KR 20030068696 A KR20030068696 A KR 20030068696A
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stat3
stem cells
transplantation
cells
engraftment
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KR1020020008272A
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English (en)
Korean (ko)
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오일환
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오일환
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Priority to KR1020020008272A priority Critical patent/KR20030068696A/ko
Priority to AU2003245073A priority patent/AU2003245073A1/en
Priority to KR1020047012711A priority patent/KR101027288B1/ko
Priority to PCT/IB2003/000515 priority patent/WO2003068952A1/en
Priority to JP2003568067A priority patent/JP4834291B2/ja
Priority to US10/369,053 priority patent/US7510870B2/en
Publication of KR20030068696A publication Critical patent/KR20030068696A/ko
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0647Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48Reproductive organs
    • A61K35/51Umbilical cord; Umbilical cord blood; Umbilical stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48Reproductive organs
    • A61K35/54Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
    • A61K35/545Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60Transcription factors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00Coculture with; Conditioned medium produced by
    • C12N2502/99Coculture with; Conditioned medium produced by genetically modified cells

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Reproductive Health (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gynecology & Obstetrics (AREA)
  • Oncology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020020008272A 2002-02-15 2002-02-15 스탓3 (stat3) 분자 활성화에 의한 줄기세포의 생체내이식생착효율 증가 Pending KR20030068696A (ko)

Priority Applications (6)

Application Number Priority Date Filing Date Title
KR1020020008272A KR20030068696A (ko) 2002-02-15 2002-02-15 스탓3 (stat3) 분자 활성화에 의한 줄기세포의 생체내이식생착효율 증가
AU2003245073A AU2003245073A1 (en) 2002-02-15 2003-02-17 Stat3 activated stem cell
KR1020047012711A KR101027288B1 (ko) 2002-02-15 2003-02-17 스탓3 활성화 줄기세포
PCT/IB2003/000515 WO2003068952A1 (en) 2002-02-15 2003-02-17 Stat3 activated stem cell
JP2003568067A JP4834291B2 (ja) 2002-02-15 2003-02-17 Stat3活性化幹細胞
US10/369,053 US7510870B2 (en) 2002-02-15 2003-02-18 STAT3 activated stem cell

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020020008272A KR20030068696A (ko) 2002-02-15 2002-02-15 스탓3 (stat3) 분자 활성화에 의한 줄기세포의 생체내이식생착효율 증가

Publications (1)

Publication Number Publication Date
KR20030068696A true KR20030068696A (ko) 2003-08-25

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020020008272A Pending KR20030068696A (ko) 2002-02-15 2002-02-15 스탓3 (stat3) 분자 활성화에 의한 줄기세포의 생체내이식생착효율 증가
KR1020047012711A Expired - Fee Related KR101027288B1 (ko) 2002-02-15 2003-02-17 스탓3 활성화 줄기세포

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020047012711A Expired - Fee Related KR101027288B1 (ko) 2002-02-15 2003-02-17 스탓3 활성화 줄기세포

Country Status (5)

Country Link
US (1) US7510870B2 (https=)
JP (1) JP4834291B2 (https=)
KR (2) KR20030068696A (https=)
AU (1) AU2003245073A1 (https=)
WO (1) WO2003068952A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101322889B1 (ko) * 2004-08-16 2013-10-30 셀리서치 코포레이션 피티이 리미티드 제대의 양막으로부터 줄기/전구세포의 추출
US7838503B2 (en) * 2005-06-15 2010-11-23 Children's Medical Center Corporation Methods for extending the replicative lifespan of cells
WO2007030693A2 (en) * 2005-09-08 2007-03-15 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Methods for promoting stem cell proliferation and survival
AU2008289209A1 (en) * 2007-08-16 2009-02-26 The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services Methods for promoting stem cell proliferation and survival
US8445517B2 (en) 2009-12-11 2013-05-21 Dana-Farber Cancer Institute Stat modulators
EP2630232A4 (en) * 2010-10-22 2014-04-02 Biotime Inc METHOD FOR MODIFYING TRANSCRIPTIONAL REGULATORY NETWORKS IN STEM CELLS
WO2013010045A1 (en) 2011-07-12 2013-01-17 Biotime Inc. Novel methods and formulations for orthopedic cell therapy
US20190127700A1 (en) * 2016-04-06 2019-05-02 The Catholic University Of Korea Industry-Academic Cooperation Foundation Technique for Enhancing Stem Cell Regeneration Through Interaction of Vascular Endothelial Cell and Mesenchymal Stem Cell
US20210222128A1 (en) * 2020-01-22 2021-07-22 Massachusetts Institute Of Technology Inducible tissue constructs and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4645791A (en) * 1985-06-24 1987-02-24 Ford Motor Company Environmentally durable elastomer composition with excellent low temperature dynamic properties
US6235873B1 (en) * 1999-07-31 2001-05-22 The Rockefeller University Constitutively active transcription factors and their uses for identifying modulators of activity including dysproliferative cellular changes

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Annu.Rev.Biomed.Eng., Peter W.Zandstra et al., 2001, Vol.3, p.275-305 *
Proc.Natl.Acad.Sci.USA, Regina Raz et al., 1999, Vol.96, p.2846-2851 *
The EMBO Journal, Takahiko Matsuda et al., 1999, 18(15),p.4261-4269 *

Also Published As

Publication number Publication date
US20030157711A1 (en) 2003-08-21
JP2005517404A (ja) 2005-06-16
KR20040084918A (ko) 2004-10-06
JP4834291B2 (ja) 2011-12-14
WO2003068952A1 (en) 2003-08-21
KR101027288B1 (ko) 2011-04-06
AU2003245073A1 (en) 2003-09-04
US7510870B2 (en) 2009-03-31

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