KR20010089983A - Camouflage cream composition for mosquito control - Google Patents
Camouflage cream composition for mosquito control Download PDFInfo
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- KR20010089983A KR20010089983A KR1020000018559A KR20000018559A KR20010089983A KR 20010089983 A KR20010089983 A KR 20010089983A KR 1020000018559 A KR1020000018559 A KR 1020000018559A KR 20000018559 A KR20000018559 A KR 20000018559A KR 20010089983 A KR20010089983 A KR 20010089983A
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- 239000000203 mixture Substances 0.000 title claims abstract description 29
- 239000006071 cream Substances 0.000 title claims abstract description 12
- 241000255925 Diptera Species 0.000 title abstract description 9
- 239000000049 pigment Substances 0.000 claims abstract description 9
- 239000004166 Lanolin Substances 0.000 claims abstract description 5
- 229940039717 lanolin Drugs 0.000 claims abstract description 5
- 235000019388 lanolin Nutrition 0.000 claims abstract description 5
- 239000001993 wax Substances 0.000 claims abstract description 5
- 239000004215 Carbon black (E152) Substances 0.000 claims abstract description 4
- 235000014113 dietary fatty acids Nutrition 0.000 claims abstract description 4
- 239000000194 fatty acid Substances 0.000 claims abstract description 4
- 229930195729 fatty acid Natural products 0.000 claims abstract description 4
- -1 fatty acid ester Chemical class 0.000 claims abstract description 4
- 150000002191 fatty alcohols Chemical class 0.000 claims abstract description 4
- 229930195733 hydrocarbon Natural products 0.000 claims abstract description 4
- 150000002430 hydrocarbons Chemical class 0.000 claims abstract description 4
- 229940057995 liquid paraffin Drugs 0.000 claims abstract description 4
- 239000003795 chemical substances by application Substances 0.000 claims abstract 2
- 239000000077 insect repellent Substances 0.000 claims description 17
- 230000002496 gastric effect Effects 0.000 claims description 8
- 239000003921 oil Substances 0.000 claims description 7
- WNLRTRBMVRJNCN-UHFFFAOYSA-N adipic acid Chemical compound OC(=O)CCCCC(O)=O WNLRTRBMVRJNCN-UHFFFAOYSA-N 0.000 claims description 4
- 239000010632 citronella oil Substances 0.000 claims description 4
- GHVNFZFCNZKVNT-UHFFFAOYSA-N decanoic acid Chemical compound CCCCCCCCCC(O)=O GHVNFZFCNZKVNT-UHFFFAOYSA-N 0.000 claims description 4
- POULHZVOKOAJMA-UHFFFAOYSA-N dodecanoic acid Chemical compound CCCCCCCCCCCC(O)=O POULHZVOKOAJMA-UHFFFAOYSA-N 0.000 claims description 4
- IPCSVZSSVZVIGE-UHFFFAOYSA-N hexadecanoic acid Chemical compound CCCCCCCCCCCCCCCC(O)=O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 claims description 4
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 claims description 4
- 235000019271 petrolatum Nutrition 0.000 claims description 4
- 150000004671 saturated fatty acids Chemical class 0.000 claims description 4
- 235000021122 unsaturated fatty acids Nutrition 0.000 claims description 4
- 150000004670 unsaturated fatty acids Chemical class 0.000 claims description 4
- WBVGGGQBQHMEFT-UHFFFAOYSA-N 2,3-diethyl-6-methylbenzamide N,N-diethyl-3-methylbenzamide Chemical compound CCN(CC)C(=O)C1=CC=CC(C)=C1.CCC1=CC=C(C)C(C(N)=O)=C1CC WBVGGGQBQHMEFT-UHFFFAOYSA-N 0.000 claims description 3
- 239000004264 Petrolatum Substances 0.000 claims description 3
- 235000021355 Stearic acid Nutrition 0.000 claims description 3
- 239000002253 acid Substances 0.000 claims description 3
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 claims description 3
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 claims description 3
- 229940066842 petrolatum Drugs 0.000 claims description 3
- 239000000546 pharmaceutical excipient Substances 0.000 claims description 3
- 239000008117 stearic acid Substances 0.000 claims description 3
- OYHQOLUKZRVURQ-NTGFUMLPSA-N (9Z,12Z)-9,10,12,13-tetratritiooctadeca-9,12-dienoic acid Chemical compound C(CCCCCCC\C(=C(/C\C(=C(/CCCCC)\[3H])\[3H])\[3H])\[3H])(=O)O OYHQOLUKZRVURQ-NTGFUMLPSA-N 0.000 claims description 2
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 claims description 2
- DSSYKIVIOFKYAU-XCBNKYQSSA-N (R)-camphor Chemical compound C1C[C@@]2(C)C(=O)C[C@@H]1C2(C)C DSSYKIVIOFKYAU-XCBNKYQSSA-N 0.000 claims description 2
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 claims description 2
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 claims description 2
- 239000005632 Capric acid (CAS 334-48-5) Substances 0.000 claims description 2
- 239000005635 Caprylic acid (CAS 124-07-2) Substances 0.000 claims description 2
- 241000723346 Cinnamomum camphora Species 0.000 claims description 2
- YUXIBTJKHLUKBD-UHFFFAOYSA-N Dibutyl succinate Chemical compound CCCCOC(=O)CCC(=O)OCCCC YUXIBTJKHLUKBD-UHFFFAOYSA-N 0.000 claims description 2
- 239000005639 Lauric acid Substances 0.000 claims description 2
- 239000005642 Oleic acid Substances 0.000 claims description 2
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 claims description 2
- 235000021314 Palmitic acid Nutrition 0.000 claims description 2
- 239000001361 adipic acid Substances 0.000 claims description 2
- 235000011037 adipic acid Nutrition 0.000 claims description 2
- DTOSIQBPPRVQHS-PDBXOOCHSA-N alpha-linolenic acid Chemical compound CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O DTOSIQBPPRVQHS-PDBXOOCHSA-N 0.000 claims description 2
- 235000020661 alpha-linolenic acid Nutrition 0.000 claims description 2
- 229960000846 camphor Drugs 0.000 claims description 2
- 229930008380 camphor Natural products 0.000 claims description 2
- 239000010627 cedar oil Substances 0.000 claims description 2
- 229960002097 dibutylsuccinate Drugs 0.000 claims description 2
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 claims description 2
- 229960004488 linolenic acid Drugs 0.000 claims description 2
- KQQKGWQCNNTQJW-UHFFFAOYSA-N linolenic acid Natural products CC=CCCC=CCC=CCCCCCCCC(O)=O KQQKGWQCNNTQJW-UHFFFAOYSA-N 0.000 claims description 2
- WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 claims description 2
- 229960002446 octanoic acid Drugs 0.000 claims description 2
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 claims description 2
- 229960002969 oleic acid Drugs 0.000 claims description 2
- WBHHMMIMDMUBKC-XLNAKTSKSA-N ricinelaidic acid Chemical compound CCCCCC[C@@H](O)C\C=C\CCCCCCCC(O)=O WBHHMMIMDMUBKC-XLNAKTSKSA-N 0.000 claims description 2
- 229960003656 ricinoleic acid Drugs 0.000 claims description 2
- FEUQNCSVHBHROZ-UHFFFAOYSA-N ricinoleic acid Natural products CCCCCCC(O[Si](C)(C)C)CC=CCCCCCCCC(=O)OC FEUQNCSVHBHROZ-UHFFFAOYSA-N 0.000 claims description 2
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 230000003020 moisturizing effect Effects 0.000 claims 1
- TUNFSRHWOTWDNC-HKGQFRNVSA-N tetradecanoic acid Chemical compound CCCCCCCCCCCCC[14C](O)=O TUNFSRHWOTWDNC-HKGQFRNVSA-N 0.000 claims 1
- MMOXZBCLCQITDF-UHFFFAOYSA-N N,N-diethyl-m-toluamide Chemical compound CCN(CC)C(=O)C1=CC=CC(C)=C1 MMOXZBCLCQITDF-UHFFFAOYSA-N 0.000 abstract description 4
- 229940099259 vaseline Drugs 0.000 abstract 1
- 239000000975 dye Substances 0.000 description 6
- 239000004480 active ingredient Substances 0.000 description 5
- 230000000694 effects Effects 0.000 description 4
- 241000607479 Yersinia pestis Species 0.000 description 3
- 229960001673 diethyltoluamide Drugs 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 239000003960 organic solvent Substances 0.000 description 2
- 208000001490 Dengue Diseases 0.000 description 1
- 206010012310 Dengue fever Diseases 0.000 description 1
- 206010014596 Encephalitis Japanese B Diseases 0.000 description 1
- 208000010201 Exanthema Diseases 0.000 description 1
- 201000005807 Japanese encephalitis Diseases 0.000 description 1
- 241000710842 Japanese encephalitis virus Species 0.000 description 1
- 208000004554 Leishmaniasis Diseases 0.000 description 1
- 239000004909 Moisturizer Substances 0.000 description 1
- 206010035148 Plague Diseases 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 208000011312 Vector Borne disease Diseases 0.000 description 1
- 208000003152 Yellow Fever Diseases 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 239000000443 aerosol Substances 0.000 description 1
- 239000001569 carbon dioxide Substances 0.000 description 1
- 229910002092 carbon dioxide Inorganic materials 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000007123 defense Effects 0.000 description 1
- 208000025729 dengue disease Diseases 0.000 description 1
- 208000028104 epidemic louse-borne typhus Diseases 0.000 description 1
- 201000005884 exanthem Diseases 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- 201000004792 malaria Diseases 0.000 description 1
- 230000001333 moisturizer Effects 0.000 description 1
- 208000027753 pain disease Diseases 0.000 description 1
- 239000000575 pesticide Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 206010037844 rash Diseases 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 235000015096 spirit Nutrition 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 206010061393 typhus Diseases 0.000 description 1
- 239000003871 white petrolatum Substances 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/18—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N<, e.g. carboxylic acid amides or imides; Thio analogues thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/02—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings containing insect repellants
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F41—WEAPONS
- F41H—ARMOUR; ARMOURED TURRETS; ARMOURED OR ARMED VEHICLES; MEANS OF ATTACK OR DEFENCE, e.g. CAMOUFLAGE, IN GENERAL
- F41H3/00—Camouflage, i.e. means or methods for concealment or disguise
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Agronomy & Crop Science (AREA)
- Dermatology (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicinal Preparation (AREA)
Abstract
Description
본 발명은 모기퇴치제를 군인들이 사용하는 위장용 크림 형태로 제조하여 적으로부터의 노출방지와 모기퇴치를 병행하며 그 효력이 장시간 지속되도록 한 모기퇴치제 조성물에 관한 것이다.The present invention relates to a mosquito repellent composition prepared by preparing a mosquito repellent in the form of a camouflage cream used by soldiers to prevent exposure from the enemy and mosquito repellent, so that the effect lasts for a long time.
모기는 세계적인 분포를 하고 있어 열대지방과 온대지방은 물론이고 극지부근에서도 서식한다. 또한 지하터널, 깊은 탄광내 및 해발 4000m 높이에서도 발견된다. 일반적으로 열대지방에 더 많은 것이 사실이나 북방지역에도 높은 발생밀도를 보이는 곳도 많다. 인류 보건 역사상 가장 중요한 질병은 대부분 곤충이 매개하는 것들로서 말라리아, 사상충증, 뎅그열, 황열, 흑사병, 수면병, 발진티프스, 리슈마니아증 등이 있고 우리나라의 경우는 일본뇌염, 쓰쓰가무시병 등이 있다. 그리고 이러한 곤충 매개성 질환중 많은 것이 모기에 의해 전염되고 있다.Mosquitoes have a worldwide distribution and live in the tropics and temperate regions as well as in the polar regions. It is also found in underground tunnels, deep mines, and at an altitude of 4000 meters above sea level. In general, more is true in the tropics, but many have high density in the north. The most important diseases in the history of human health are mostly insect-borne media such as malaria, filamentous fever, dengue fever, yellow fever, plague, sleep sickness, rash typhus, and leishmaniasis. In Korea, Japanese encephalitis and Tsutsuga musiosis. And many of these insect-borne diseases are transmitted by mosquitoes.
특히, 모기가 많이 서식하는 노출된 외부환경에서 장시간 경계근무를 서야 하는 군인들의 경우에는 모기에 의한 피해가 더욱 크다고 할 수 있다. 군인들은야간 경계근무시 적에게 노출되는 것을 방지하기 위하여 주변 환경과 유사한 색의 안료 또는 염료가 섞인 야간 위장용 크림을 사용하게 된다. 그러나 여름철 야외에서 현재의 야간위장용 크림을 바르고 근무를 설 경우 근무자의 호흡으로 인한 주위의 이산화탄소 농도상승과 인체의 배출가스 등에 의해 모기들이 근무자를 집중 공격하게 된다. 따라서, 근무자의 신체적 고통과 모기매개성 질환의 감염우려는 물론 근무자의 본능적인 방어, 즉 모기의 공격을 받은 근무자가 간지럽거나 따가운 느낌을 받아 본인의 신체를 때리게 됨으로써 적에게 노출될 위험까지 있게 된다.In particular, the mosquitoes are more likely to be affected by soldiers who have to stay alert for a long time in the exposed external environment where mosquitoes live more. Soldiers use night-time camouflage creams that are mixed with pigments or dyes of similar color to their surroundings to prevent exposure to enemies at night. However, when working outdoors with the current night gastrointestinal cream in summer, mosquitoes will attack workers by increasing concentration of carbon dioxide due to worker's breathing and exhaust gas of human body. Therefore, the worker's physical pain and mosquito-borne disease are not only infected, but the worker's instinctive defense, that is, the worker who is attacked by the mosquitoes and smacks his body and hits his body. .
이러한 이유로 군인들은 피부나 의류에 모기퇴치제를 뿌리고 야간 근무를 서게 된다. 현재 인체에 직·간접적으로 적용하는 모기퇴치제로는 노출된 신체의 일부에 도포 적용하는 타입과 의류에 뿌리는 에어로졸 타입 등이 있다. 그러나 어느 타입이든 현재의 모기퇴치제는 유기용매가 많이 함유된 혼합물의 형태이기 때문에 모기퇴치의 효능시간이 짧아 자주 반복하여 도포 또는 분무하여야 하므로 장시간 경계근무를 서거나 또는 적진에서 싸워야 하는 군인들이 사용하기에는 적합하지 않으며, 또한 야간 근무시 군인들은 야간 위장용 크림과 모기퇴치제를 각각 별개로 사용하여야 하므로 이에 따른 불편이 있다.For this reason, soldiers stay at night with mosquito repellents on their skin or clothing. Currently, mosquito repellents applied directly or indirectly to the human body include a type applied to a part of the exposed body and an aerosol type applied to clothing. However, since the current mosquito repellent is in the form of a mixture containing a lot of organic solvents, the potency of mosquito repellent is short, so it has to be applied or sprayed frequently repeatedly. It is not suitable, and also during the night duty soldiers have to use the night camouflage cream and mosquito repellent separately, so there is inconvenience.
이에 본 발명자는 군인들이 어차피 사용하여야 하는 위장용 크림의 형태로 모기퇴치제를 제조하고 그 효능을 장시간 지속화시킬 수 있는 제제에 관해 연구한 결과 본 발명에 이르게 되었다.Accordingly, the present inventors have studied the preparation of a mosquito repellent in the form of gastrointestinal creams which should be used by soldiers anyway, and the present invention has been studied.
본 발명은 군인들이 어차피 사용하여야 하는 위장용 크림의 형태로 모기퇴치제를 제조함으로써 적으로부터의 노출방지와 모기퇴치를 병행하도록 하는 것을 목적으로 한다.An object of the present invention is to prepare a mosquito repellent in the form of camouflage cream that soldiers should use anyway to prevent exposure from enemy and mosquito repellent.
또한, 본 발명은 장시간 근무를 서는 군인들이 사용하기에 적합하도록 효능이 장시간 발휘되도록 한 모기퇴치제를 제공하는 것을 목적으로 한다.In addition, an object of the present invention is to provide a mosquito repellent having a long time efficacy to be suitable for use by soldiers standing for a long time.
상기와 같은 목적을 달성하기 위하여, 본 발명에서는 (a) 바셀린, 유동파라핀, 플라스티베이스, 정제라놀린, 탄화수소 오일, 지방산 에스테르, 지방알콜, 왁스 및 이들의 혼합물로 구성된 군으로부터 선택된 친유성 기제 25∼80 중량부; (b) 안료 또는 염료 5∼20 중량부; 및 (c) 디에틸톨루아미드(N,N-diethyl-m-toluamide) 2∼45 중량부를 포함하는 것을 특징으로 하는 위장용 크림 형태의 모기퇴치제 조성물을 제공한다.In order to achieve the above object, in the present invention (a) lipophilic base selected from the group consisting of petrolatum, liquid paraffin, plastibase, purified lanolin, hydrocarbon oils, fatty acid esters, fatty alcohols, waxes and mixtures thereof 80 parts by weight; (b) 5 to 20 parts by weight of pigment or dye; And (c) 2 to 45 parts by weight of diethyltoluamide (N, N-diethyl-m-toluamide).
이하, 본 발명을 상세히 설명한다.Hereinafter, the present invention will be described in detail.
본 조성물 중의 친유성 기제는 바셀린, 유동파라핀, 플라스티베이스, 정제라놀린, 탄화수소 오일, 지방산 에스테르, 지방알콜, 왁스 및 이들의 혼합물로 구성된 군으로부터 선택된다.The lipophilic base in the composition is selected from the group consisting of petrolatum, liquid paraffin, plastibase, purified lanolin, hydrocarbon oils, fatty acid esters, fatty alcohols, waxes and mixtures thereof.
더욱 바람직하게는 상기 친유성 기제는 포화지방산 및 불포화지방산을 함유하는 천연오일 및 합성오일로서, 상기 포화지방산은 아디프산, 카프릴산, 카프르산, 라우르산, 미리스트산, 팔미트산, 스테아르산 및 이들의 혼합물로 구성된 군으로부터 선택되고, 상기 불포화지방산은 리놀레산, 리롤렌산, 리시놀레산, 올레산, 엘라이드산 및 이들의 혼합물로 구성된 군으로부터 선택된다.More preferably, the lipophilic base is a natural oil and a synthetic oil containing saturated fatty acid and unsaturated fatty acid, wherein the saturated fatty acid is adipic acid, caprylic acid, capric acid, lauric acid, myristic acid, palmitic. Acid, stearic acid and mixtures thereof, the unsaturated fatty acid is selected from the group consisting of linoleic acid, linolenic acid, ricinoleic acid, oleic acid, ellide acid and mixtures thereof.
본 조성물에는 안료 또는 염료가 5∼20 중량부 포함된다. 안료 또는 염료는 군인이 적에게 노출되는 것을 방지하기 위하여 주변 환경과 유사한 색을 선택하여 사용하며, 인체에 대한 안전성이 확보된 공지의 모든 안료 또는 염료가 사용 가능하다.The composition contains 5 to 20 parts by weight of a pigment or dye. Pigments or dyes are used by selecting a color similar to the surrounding environment in order to prevent soldiers from being exposed to the enemy, all known pigments or dyes that can ensure the safety to the human body can be used.
본 조성물은 모기퇴치의 유효성분으로 디에틸톨루아미드(N,N-diethyl-m-toluamide) 2∼40 중량부를 포함한다.The composition contains 2 to 40 parts by weight of diethyltoluamide (N, N-diethyl-m-toluamide) as an active ingredient for mosquito repellent.
또한, 본 발명의 조성물에는 보습제가 5∼10 중량부 포함될 수 있다.In addition, the composition of the present invention may contain 5 to 10 parts by weight of a moisturizer.
또한, 본 발명의 조성물에는 디부틸석시네이트(Dibutyl succinate), 시더유(Cedar oil), 시트로넬라-유(Citronella oil), 캄파정(Spirits of Camphor)과 같은 첨가제가 부가될 수 있으며, 이밖에도 제제의 안정성, 도포성, 사용성, 방향성, 보존성 등을 향상시키기 위한 통상의 약제학적 첨가제가 부가될 수 있다.In addition, additives such as dibutyl succinate, cedar oil, citronella oil, Citronella oil, and Spirits of Camphor may be added to the composition of the present invention. In addition, conventional pharmaceutical additives may be added to improve the stability, applicability, usability, fragrance, preservation, and the like of the formulation.
본 발명에 따른 조성물은 친유성 베이스와 안료 또는 염료를 혼합하고 70∼150℃로 가열한 후 디에틸톨루아미드를 혼합·교반하고 곧바로 냉각하는 방법으로 제조한다.The composition according to the present invention is prepared by mixing a lipophilic base with a pigment or dye, heating to 70-150 ° C., then mixing and stirring diethyltoluamide and immediately cooling it.
이하, 다음의 실시예를 통해 본 발명을 보다 상세하게 설명한다. 그러나 다음의 실시예에 의해 본 발명의 범위가 한정되는 것은 아니다.Hereinafter, the present invention will be described in more detail with reference to the following examples. However, the scope of the present invention is not limited by the following examples.
실시예 1Example 1
(제조예)(Production example)
팔미트산, 스테아르산의 트리글리세라이드와 왁스로 구성된 친유성 기제 60 중량부에 안료 5 중량부를 가하고 90℃로 가열한 후 디에틸톨루아미드 20 중량부를 가하여 완전히 혼합·교반한 후 상온으로 냉각하여 본 발명의 위장용 크림 형태의 해충퇴치제 조성물을 제조하였다.To 60 parts by weight of a lipophilic base consisting of palmitic acid and stearic acid and a wax, 5 parts by weight of a pigment was added thereto, heated to 90 ° C., 20 parts by weight of diethyltoluamide was added, mixed and stirred thoroughly, and then cooled to room temperature. A pest control composition in the form of a gastrointestinal cream of the present invention was prepared.
실시예 2Example 2
(제조예)(Production example)
친유성 기제로 정제 라놀린을 사용하는 것을 제외하고는 실시예 1과 동일한 방법으로 위장용 크림 형태의 해충퇴치제 조성물을 제조하였다.A gastrointestinal pest control composition was prepared in the same manner as in Example 1 except for using the purified lanolin as a lipophilic base.
실시예 3Example 3
(제조예)(Production example)
친유성 기제로 정제된 백색 바셀린을 사용하는 것을 제외하고는 실시예 1과 동일한 방법으로 위장용 크림 형태의 해충퇴치제 조성물을 제조하였다.A pesticide composition in the form of a gastrointestinal cream was prepared in the same manner as in Example 1 except for using white petrolatum purified as a lipophilic base.
실시예 4Example 4
효과테스트Effect test
상기 실시예에서 제조한 본 발명의 조성물을 피부에 도포한 후 시간의 경과에 따른 유효성분(디에틸톨루아미드)의 잔류량을 측정하였다. 도포시 유효성분의 함량을 100%하여 측정된 결과를 나타내었다. 결과는 다음의 표 1과 같다.After applying the composition of the present invention prepared in the above Example to the skin was measured the residual amount of the active ingredient (diethyl toluamide) over time. The results were measured by 100% of the content of the active ingredient at the time of application. The results are shown in Table 1 below.
유기용매를 다량 함유하는 기존제제의 경우 도포 후 4시간이 경과하면 대부분 유효성분의 함량이 50% 이하로 감소되나, 상기 표 1로부터 알 수 있는 바와 같이 본 발명의 조성물은 도포 후 4시간이 경과한 때에도 유효성분이 65% 이상 잔류하여 효력이 보다 장시간 지속됨을 알 수 있다.In the case of existing formulations containing a large amount of organic solvent, the content of the active ingredient is reduced to 50% or less after 4 hours of application. It can be seen that the active ingredient lasts more than 65% even at one time.
본 발명의 조성물은 경계근무를 서는 군인들이 어차피 사용하여야 하는 위장용 크림의 형태로 모기퇴치제를 제조함으로써 위장효과와 모기퇴치효과를 동시에 거두고 또한 효능을 장시간 발휘하도록 함으로써 군인들이 간편하고 손쉽게 사용할 수 있도록 한다.The composition of the present invention by preparing a mosquito repellent in the form of a gastrointestinal cream that must be used by the soldiers who are on duty at the same time to achieve the gastrointestinal effect and mosquito repellent effect at the same time, and to exhibit the effect for a long time so that soldiers can use easily and easily do.
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| KR1020000018559A KR100383886B1 (en) | 2000-04-10 | 2000-04-10 | Camouflage cream composition for mosquito control |
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| KR1020000018559A KR100383886B1 (en) | 2000-04-10 | 2000-04-10 | Camouflage cream composition for mosquito control |
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| KR20190123909A (en) | 2018-04-25 | 2019-11-04 | 숙명여자대학교산학협력단 | Environmentally friendly camouflage cosmetic composition |
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