KR20010052418A - Liquid Medicine Preparing Device - Google Patents

Abstract

The present invention relates to an apparatus for preparing a pharmaceutical solution by mixing and dissolving a solid and a liquid medicine by a water stream. The present invention is a device for preparing a drug solution by dissolving and mixing a drug into the water passing through the water supply passage, the device is an inlet (1) for introducing water and water introduced from the inlet (1) And a container having an outlet (3) for discharging the gas, a water passage from the inlet (1) to the outlet (3), and a medicine chamber (4) for accommodating the medicine, and the medicine contained in the medicine chamber (4). Dissolves in contact with water passing through the water channel. This makes it possible to dissolve the drug easily and safely.

Description

Pharmaceutical Solution Preparation Device

Conventionally, many methods for dissolving a drug in solid or liquid form in water are known. However, all of these methods simply could not prepare a desired pharmaceutical solution or required an apparatus such as a stirrer.

Also, conventionally, a method is known in which an effective sterilizing water can be obtained by electrolyzing saline. This electrolysis method is suitable for preparing sterilized water in a large-scale facility that requires a large amount of sterilized water, but it is suitable for preparing sterilized water in a relatively small facility because it requires expensive facilities. Not.

On the other hand, as a method of using the saline solution instead of the electrolysis method, a method of producing sterile water by combining drugs is proposed. For example, Japanese Patent Laid-Open No. Hei 10-81610 discloses a method of dissolving a sterilizing agent consisting of a chlorine agent and a powder in water to prepare an acidic sterilizing water. This fungicide was considered to be useful in that sterilization water similar to the sterilization water obtained by the above-described electrolysis method can be obtained.

However, no suitable means have been developed for easily dissolving solid and liquid fungicides in water. Therefore, it was necessary to disinfect the disinfectant in a tank in which water was accumulated and stir with a stirrer or a stirring rod to dissolve it, or to disinfect the disinfectant in an empty tank and flush the water. For this reason, it took time until the disinfectant did not melt | dissolve completely or it dissolves completely. In addition, in the case of the disinfectant which generates chlorine, if the generated chlorine is not dissolved in water efficiently, the concentration of chlorine in the air becomes high and the working environment is contaminated.

[Technical Challenges]

An object of the present invention is to provide a pharmaceutical solution preparation device for preparing a pharmaceutical solution by dissolving a drug, in particular a fungicide, easily and safely in water.

[Resolution]

The inventors of the present invention have repeatedly examined aberrations in order to solve the above problems, and as a result, a device for dissolving and incorporating a drug into water passing through the water supply passage, the device is used to introduce water. A container having an inlet, an outlet for discharging water introduced from the inlet, a water passage from the inlet to the outlet, and a medicine chamber for accommodating a medicine, wherein the medicine contained in the medicine chamber passes through the water channel. It has been found that the above problems are solved by using a pharmaceutical solution preparation device, characterized in that it is dissolved in contact with water. The present invention is explained in more detail below.

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an apparatus for preparing a pharmaceutical solution by mixing and dissolving a solid and a liquid in a liquid form by water flow. More particularly, the present invention relates to sterilization used in various fields such as medical care, food, general households, and swimming pools. A pharmaceutical solution preparation device for preparing water.

1 is a cross-sectional view of a pharmaceutical solution preparation device according to an embodiment of the present invention in a state capable of releasing a pharmaceutical solution in the form of a shower.

2 is a cross-sectional view of a pharmaceutical solution preparation device according to one embodiment of the present invention in a state capable of releasing the pharmaceutical solution in the form of straights.

3 is a bottom view of a pharmaceutical solution preparation device according to one embodiment of the present invention.

4 is a cross-sectional view of a pharmaceutical solution preparation device according to one embodiment of the present invention.

5 is a view illustrating a state in which a faucet is mounted and used.

6 is a view showing a state in which the apparatus according to the present invention is mounted on a circulating water supply passage.

7 shows a device according to the invention mounted on a tank.

8 shows a device according to the invention mounted on a tank with a stirrer.

9 is a sectional view of a cartridge type pharmaceutical solution preparation device according to the present invention.

10 is a cross-sectional view of a continuous pharmaceutical solution preparation device according to the present invention.

Next, the present invention will be described in more detail with reference to Examples.

The present invention can be designed in a single use type for putting a single amount of a medicine into a pharmaceutical solution preparation device and a continuous double type for putting a plurality of medicines in succession several times. The disposable type is described as the first embodiment and the continuous type is described as the second embodiment.

[First Embodiment]

1 to 3 is a pharmaceutical solution preparation device 101 according to an embodiment of the present invention. This chemical | medical agent solution preparation apparatus 1 is attached to a faucet, and is a disposable type apparatus which uses all the quantity of the chemical | medical agent injected once at once.

The chemical solution preparation device 101 is constituted by a container including an upper case 2 and a lower case 5 having a chemical chamber 4 therein, an inlet 1 for introducing water, and the inlet. An outlet 3 for discharging the water introduced from (1), a water passage from the inlet 1 to the outlet 3, and a chemical chamber 4 for accommodating the medicine are provided.

The inlet 1 formed in the upper case 2 is provided with a mounting hole consisting of a packing 7, a guard-shaped assisting tool 8, and a fixing tool 9 so as to be mounted on the faucet 6. Have When attaching this mounting hole to a faucet, the pipe part of a faucet is first inserted into the hole part 9 'formed in the fixture, and a guard-shaped mounting hole is attached to the guard part 6' of the faucet. 8), the faucet 6 with the guard-shaped mounting hole is brought into contact with the packing 7, and the nut screw 11 formed in the fastener and the bolt screw 12 formed in the upper case are engaged. By fixing. In the apparatus of the present invention attached to the faucet as described above, water is introduced into the chemical chamber 4 when the faucet is opened.

This chemical | medical agent chamber 4 consists of the large diameter wall part 17 and the bottom part 18, and the small diameter wall part 16 is provided inside the large diameter wall part 17 of this chemical | medical agent room. Therefore, the chemical | medical agent room of this invention is divided into two chambers which consist of the small diameter groove part 20 and the wheel-shaped groove part 21 formed in the outer side. In the bottom portion 18 constituting the medicine chamber, a portion of the bottom portion 18 corresponding to the wheel-shaped groove portion 21 is formed with small pores 22 small in size so that the undissolved drug does not escape downstream. A large hole 23 having a relatively large dimension is formed in a portion corresponding to the small-diameter groove 20, and a filter 8 is attached to the large hole 23.

Since water flows in the chemical | medical agent room 4 vigorously, the chemical | medical agent put into the small diameter recessed part 20 and the wheel-shaped recessed part 21 is melt-mixed. Moreover, since the bottom part of the chemical | medical agent chamber becomes the small hole 22 which does not let the filter 8 and the undissolved chemical | medical agent pass, only the chemical | medical agent which melt | dissolved completely passes through a filter. Therefore, dissolution is accelerated by running water without passing the undissolved drug.

Arbitrary drugs can be put into the chemical | medical agent room of this invention. The drug suitable for being put into the medicine chamber of the present invention is as described later. However, since the medicine chamber 4 is divided into two chambers, the small-diameter recess 20 and the wheel-shaped recess 21, for example, a chlorine agent. In the case of separately putting two kinds of chemicals which do not want to be mixed before use, such as a disinfectant made of powder and powder, for example, chlorine is added to the small groove 20 and powder to the wheel-shaped groove 21. I can put it. In addition, the apparatus shown in FIG. 1 may be configured to further form a wall for partitioning the medicine chamber 5 so as to dissolve and mix more kinds of medicines. The wall for partitioning is not limited to the small-diameter wall portion 16 as in the above embodiment, but may be partitioned so as to extend upward from the bottom portion so as to put different kinds of medicines separately.

In addition, since the height of the wall 16 for dividing the small-diameter recessed portion 20 of the chemical chamber 4 shown in FIG. 1 is lower than the height of the large-diameter wall portion 17, when water flows into the chemical chamber, the small-diameter recessed portion The chemical | medical agent put into the encased medicine | medical agent and the wheel-shaped recessed part can move between a small diameter recessed part and a wheel-shaped recessed part mutually.

In the bottom portion of the chemical chamber, a guide tube portion 26 extending downwardly along the large hole is formed, and the disk tube 24 is attached to the guide tube portion 26. Below this disk, the lever 10 which has the rail 32 which engages with the groove | channel 31 made inside the axial hole 34 formed in the lower case, and moves along this groove | channel 31 is mounted | worn. It is. When the lever 10 is rotated, the disk front 24 moves up and down together with the chemical chamber 4.

The lower case 5 is coupled to the upper case 2 so as to accommodate the medicine chamber therein. As shown in FIG. 3, the lower case 5 includes a shaft hole 34 formed near the center of the bottom surface thereof, and a plurality of shower holes 9 formed radially around the shaft hole 34. . In this lower case, the intermediate surface 29 on which the rectifying holes 25 are formed is formed above the lower surface, and the rectifying chamber 30 is formed. And, on the intermediate surface 29 outside the rectifying hole 25, when the front of the disk 24 is in the lowered position, formed in the shape of a wheel to prevent the drug solution from entering the rectifying hole 25 The projection 27 is provided.

Therefore, as shown in FIG. 1, when the disk 24 is in the ascending position, the drug solution prepared by dissolving the drug contained in the medicine chamber is formed by the small holes 22 and the rectifying holes 25 formed in the recesses in the wheel shape. And through the rectification chamber 30, it is discharged from the shower hole 9 into a shower shape. In addition, since the water permeability of the small holes 22 formed in the wheel-shaped recesses of the chemical chamber is larger than the water permeability of the filter 8 mounted on the small-diameter recesses, most of all chemical solutions are in the disk transition rising position. Is discharged from the shower hole (9).

On the other hand, as shown in FIG. 2, when the former 24 is in the lowered position, the rectifying hole 24 is blocked, so that the chemical solution obtained through the chemical chamber 4 passes through the filter 8. Is discharged from the shaft hole 34 as a straight stream (direct current).

As shown in FIG. 5, the outlet 3 of the drug solution preparation device 1 according to the present invention is equipped with a hose 42 for guiding the prepared drug solution to the polyethylene tank 46. The prepared chemical solution is stored in the polyethylene tank 46. 5, the confirmation window 43 for confirming the quantity of the chemical | medical agent which remains in the chemical | medical agent chamber 4 is made in the upper case 2. As shown in FIG.

In addition, when the water flowing in the water supply passage does not completely dissolve the drug by passing through the apparatus according to the present invention, such as when a drug having a relatively low solubility in water is used or when a large amount of drug is dissolved. 6, the apparatus of the present invention may be installed on a circulating water supply passage. In order to circulate the feed passage, for example, a pump 44 for pumping the solution stored in the polyethylene tank 46 back to the apparatus of the present invention is arranged as shown in FIG. 6.

In addition, the pharmaceutical solution preparation device 1 according to the present invention may be mounted on a large tank 46 ', as shown in FIG.

Furthermore, as shown in Fig. 8, a large tank may be equipped with an agitator having a motor 51 to promote dissolution of the drug.

[Drug selection]

In this invention, the kind of chemical | medical agent put into a chemical | medical agent room is not specifically limited. The agent may be in any form of liquid, solid and powder.

Preferred medicaments include, for example, a medicament consisting of a disinfectant which is dissolved in water and added sterilizing water. A medicament consisting of a powder and a chlorine agent is further mentioned.

Here, a suitable chlorine agent is selected from one or two species from the group consisting of sodium dichloroisocyanurate, sodium hypochlorite, high bleaching power and chloramine T. Suitable powders may also be used in the form of one or two species from citric acid, malic acid, tartaric acid, maleic acid, succinic acid, oxalic acid, glycolic acid, acetic acid, hydrochloric acid, sulfuric acid, nitric acid, sodium hydrogen sulfate, sulfamic acid, phosphoric acid and hydrogen peroxide. Is selected. The sterilizing water obtained by adding the above sterilizing agent to the pharmaceutical solution preparation device according to the present invention exhibits strong sterilizing action, and also has low toxicity and can drain the used sterilizing water as it is.

In addition, in the case of discharging the sterilizing water by adding the above sterilizing agent as a medicament, it is preferable to add the sterilizing agent so that the sterilizing water discharged from the apparatus according to the present invention has a pH of 5.5 or less, a redox potential of +800 kPa or more, and a residual chlorine content of 30 ppm or more. . Sterilizing water having a pH, redox potential and residual chlorine in the above ranges exhibits effective sterilizing power. In addition, sterilized water having a pH of 5.5 to 4.5, a redox potential of +800 to 1000 kPa, and a residual chlorine amount of 50 to 80 ppm is sterilized water close to weakly acidic electrolytic water, and has a pH of 2.7 or less, a redox potential of +1100 kPa and a residual chlorine of 30 to 40 ppm. The sterilizing water becomes sterilizing water close to the strongly acidic electrolytic water.

[Inspection of Solubility]

Using the apparatus according to the present invention shown as the first example, the dissolution ease of the fungicide was investigated.

In the chemical chamber described above, a bactericide (aqua acid 70) consisting of 100 l of highly bleached powder and a pH adjusting agent was placed, and 50 l of sterilized water was prepared. It was waterproofed with showers and straights at a water supply rate of 8 L / sec to 24 L / sec. After waterproofing, it was checked whether or not a fungicide remained in the drug room.

As a result, the disinfectant was completely dissolved in both the sours and the straights.

[Measurement of Chlorine Concentration]

The concentration of chlorine released into the atmosphere was investigated using a fungicide which generates chlorine upon dissolution. In the experiment, 1000 L of polyethylene tank 46 'was used to prepare 50 L of sterile water. In addition, the same amount of fungicide was used at the time of preparation of the following sample.

Sterilizing water was prepared by using a pharmaceutical solution preparation device according to the present invention in a shower at a water supply rate of 3 l / sec. Let this be sample 1.

As Comparative Example 1, a sterilant was added to water previously collected in a polyethylene tank and stirred with a stirrer to prepare sterilized water. Let this be sample 2.

As Comparative Example 2, a sterilant was added to an empty polyethylene tank, and then water was supplied at a water supply rate of 3 L / min to prepare sterilized water. Let this be sample 3.

With respect to each obtained sample, the change over time of the chlorine concentration at the height of 10 cm from the water surface was examined. Chlorine concentration was measured using a commercial gas detector. The results are shown in Table 1.

From Table 1, it can be seen that the sterilizing water prepared by the pharmaceutical solution preparation device according to the present invention significantly reduces the amount of chlorine released into the atmosphere.

TABLE 1

Chlorine concentration (ppm) Elapsed time (minutes) Sample 1 Sample 2 Sample 3 Immediately after 4 25 50 0.5 One 45 53 One One 35 52 3 0 30 45

In addition, the drug solution preparation device according to the present invention is not limited to mounting the filter 8 only on the bottom surface of the small-diameter recessed portion constituting the drug chamber, and as shown in FIG. 8 'can be mounted. In this case, it is preferable that the filter 8 'attached to the wheel-shaped groove portion has a higher water permeability than the filter 8 attached to the small-diameter groove portion 21. This makes it possible to discharge the chemical solution in the form of a shower when the disc is placed in the ascending position.

In addition, a filter is not limited to being arrange | positioned in the container of this invention provided with a chemical | medical agent chamber, For example, a filter (not shown) is put on the downstream water supply path | route of the container provided with a chemical | medical agent chamber. Can be made separately.

And it is preferable that the material which comprises the pharmaceutical solution preparation apparatus which concerns on this invention consists of a corrosion-resistant (especially acid-resistant) material.

In addition, as shown in Fig. 9, by storing the medicines in cartridges 61 and 62, each of which has a cylindrical case of upper and lower surfaces meshed, until the water flows into the channel in the pharmaceutical solution preparation device of the present invention. It is possible to prevent the drug of contact. Thus, a plurality of drugs that do not want to be preserved in a mixed state can be used in combination safely.

Second Embodiment

10 is a pharmaceutical solution preparation device according to another embodiment of the present invention. In this chemical solution preparation device, an appropriate amount of chemical is supplied to the channel for each constant amount of water flowing in the channel.

In the pharmaceutical solution preparation device, a concave portion 73 is formed in a tubular channel 71 directed to the mixing chamber 78 for mixing water and a sterilizing agent. This narrow portion 73 is equipped with two thin tubes 72 extending from the bottom surfaces of the cartridges 76 and 77 containing chlorine and powder. Therefore, when water flows into the water channel 71, the flow velocity is sharply increased in the constricted portion 73, so that the inside of the thin tube 72 is depressurized, whereby the sterilant in the cartridge is gradually sucked up. Each thin tube 72 is also equipped with a check valve (non-return valve) 74 to prevent water from entering the cartridge.

The chlorine agent and the powder sucked up from the thin tube 72 join the water in the concave portion 73, and then are supplied to the mixing chamber 4 and dissolved in the water in the mixing chamber.

In addition, as in the present embodiment, by using the aspirator principle, if the required amount of the drug is supplied to the mixing chamber and the drug other than the required amount is not wetted with water, it may be any supply means. As another supply means for realizing a continuous type, for example, a flow sensor generates a signal for promoting the supply of the sterilizer and supplies the sterilizer to the pump receiving the signal, or a sterilizer stored in the cartridge according to the flow of water. The method of releasing slowly is mentioned.

Claims (8)

In the device for preparing a drug solution by dissolving and mixing the drug in water passing through the water supply passage, The apparatus includes a container having an inlet for introducing water, an outlet for discharging water introduced from the inlet, a channel from the inlet to the outlet, and a medicine chamber for containing the medicine, The pharmaceutical solution preparation device, characterized in that the medicament contained in the drug room is dissolved in contact with the water passing through the water channel. According to claim 1, wherein the drug chamber is installed in the middle of the channel, the drug solution preparation device, characterized in that the water passing through the channel enters the drug chamber and in contact with the drug. The said chemical | medical agent chamber which comprises the said container is a recess which has a bottom provided with the ball for the water which passes through the said channel, and the wall extended upward so as to surround the outline of the said bottom. And a filter for filtering the drug which is not dissolved in the cavity. 4. The medicine chamber according to claim 3, wherein the medicine chamber further has a wall extending upwardly from the bottom in the groove portion for partitioning the inside of the groove into a plurality of rooms, wherein different medicines are formed in each of the yarns. Pharmaceutical solution preparation device characterized in that it is put in. The pharmaceutical solution preparation device according to claim 1 or 2, wherein the pharmaceutical solution preparation device has a filter for filtering the drug which is not dissolved in the middle of the channel on the downstream side rather than the container. The pharmaceutical solution preparation device according to any one of claims 1 to 5, wherein the water supply passage is circulated. The pharmaceutical solution preparation device according to any one of claims 1 to 6, wherein the medicament is a fungicide. 8. The pharmaceutical solution preparation device according to claim 7, wherein the fungicide is made of chlorine and powder.