KR20010029185A - Antiviral agent and anticancer agent containing unsaturated fatty acid extract of sasamum indicum l. and alkaline extract of potato as active ingredients - Google Patents

Abstract

PURPOSE: Provided is an antiviral agent which contains unsaturated fatty acid extract of sasamum indicum L. and alkaline extract of potato as active ingredients, shows inhibiting effects on infection of various viruses such as influenza virus and retrovirus, and on bacteria growth, as well as destroys malignant tumor without any side effect. CONSTITUTION: An antiviral agent, which comprises unsaturated fatty acid extract of sasamum indicum L. and alkaline extract of potato, as effective ingredients, is manufactured by the following steps of: washing sasamum indicum L. and drying it to lose 15% of water; heating it in a microwave followed by press extracting it to obtain unsaturated fatty acid extract thereof; washing potato and followed by press extracting it to obtain alkaline extract thereof; mixing the unsaturated fatty acid extract and the alkaline extract in a mixing ratio of 1:1. Wherein, an unsaturated fatty acid component is one of Palmiticaicd, 0.4-1.1% of Stearicaicd, 0.3-0.6% of Sesamin, 0.3-0.6% of Seamolin and Sesamol, and an alkaline component is one of 0.04mg of Vitamin B1, 0.04mg of Vitamin B2, 0.4mg of Niacin and 99mg of Vitamin C.

Description

Antiviral and Anticancer Agents {.}

The present invention relates to an antiviral agent and an anticancer agent comprising an unsaturated fatty acid of sesame seeds (Sesamum indjcum) and an alkali extract of potato (potato).

Numerous antiviral and anticancer agents have been known in the art. However, antiviral drugs mainly work only on bacteria and are extremely weak, even if they are effective against viruses. Moreover, antibiotics usually have side effects, which can sometimes be very harsh and severe.

Many diseases are caused by viruses such as influenza, hepatitis, cancer, hypotension, obesity, AIDS and diabetes, but unfortunately there are few drug treatments that show clear efficacy against these conventional viral diseases. There is no medicament that is effective enough against retroviruses that cause adult T-diabetes or AIDS.

There was also no known antiviral agent that could be taken in a daily diet and had a preventive effect without any side effects. Thus, studies on the effective treatment of HIV- and AIDS-related complexes that have no adverse effects are particularly difficult, and some medications that have limited effects through long-term chemotherapy may have serious side effects. Since anticancer drugs known as anticancer agents have not only destroyed cancer cells but also damaged normal cells, these anticancer drugs have had severe side effects. In addition, these anticancer agents have been commonly used for intravenous injection because of difficulty in oral administration. There have been many problems with these anticancer agents. Therefore, it was necessary to invent an agent which has no side effects as an anti-HIV agent and has an action of inhibiting viral adsorption on cells, inhibiting virus replication and activating immune activity.

Accordingly, an object of the present invention is to provide an anticancer agent that solves the above problems and is effective against retroviruses and destroys malignant tumors (cancer) without side effects.

The present inventors have studied diligently to solve the above problems, and as a result, unsaturated fatty acids and alkali extracts of sesame seeds (Sesamum indicum L.) and potato (Patato) have strong antiviral and anticancer activity, and the unsaturated fatty acid alkali extracts are used in animals or humans. The present invention was developed by discovering that it is extremely safe and has no side effects.

The active ingredient of the present invention is a sesame seed is settled in moisture 15%, dried in an microwave oven, heated to compression to extract the unsaturated fatty acid and pressed potatoes, vitamin C, B1, B2, nisin, pantotanic acid (B3) Inorganic nutrients such as), potassium (K), phosphorus, and calcium are destroyed when heat is applied for a long time. In order to preserve the nutrients, the mixture is extracted by applying heat in a microwave oven and then mixed with an alkaline solution in a 1: 1 ratio. The components of the unsaturated fatty acid solution include palmitic acid, stearic acid, oleic acid, linoleic acid, antioxidants, sesamin 0.4-1.1%, sesamoline 0.3-0.6%, sesamol and the like, and known extraction methods such as heating and compression extraction. Can be used. Ethanol, acetone, or the like may be used as an extraction solvent other than the heat compression extract.

The active ingredient of the extract may be mixed with a suitable carrier such as excipients, binders, or ignitants, for example, capsules, ointments, syrups, suppositories, injections, orally or parenterally, or mixed, as a solution, as the capsule In the form of a single dose, the concentrate may be used or mixed with other foods.

The dosage varies depending on the type and extent of the disease, but in the case of liquid form, 1 to 100 mg of 1 solution should be administered in 1 ml to 500 ml.

Sesame unsaturated fatty acid extract and potato alkali extract were tested in rats and mice. There was no mortality, no abnormal behavior was observed, and no value was found in blood biochemical tests and tissue pathology experiments.

The present invention is an antiviral agent, an anticancer agent, and an antibacterial agent. According to the present invention, it prevents the infection and prevents the replication of various viruses such as influenza virus and hepatitis virus and retrovirus such as adult T-diabetic or HIV (human immunodeficiency virus). It also prevents the growth or coronation of microorganisms, such as bacteria and bears, and also obtains extracts that improve and treat malignant tumors without causing any side effects.

Example

Manufacturing Example 1

Put sesame seeds in water and dry 15% of water, put them in a container and heat them in a microwave oven so that they do not burn.

Experiments were conducted on rats and mice with 1: 1 mixture of unsaturated fatty acid extracts and alkaline extracts of potatoes. No mortality was observed and no abnormal behavior was observed in the animals. Does not appear

The present invention is an antiviral agent, an anticancer agent, and an antibacterial agent. According to the present invention, it is possible to prevent infection of various viruses such as influenza virus, rotavirus and hepatitis virus, and retroviruses such as adult T-diabetes or HIV (human immunodeficiency virus). Extracts that inhibit replication, prevent the growth or enema of non-living organisms such as bacteria and fungi, and also improve and treat malignant tumors without causing any side effects can be obtained.

Experimental Example 1

NUGC-4 (1 × 10 cells / ml) extracted from cancer was injected subcutaneously into 20 rats. As a test tube from the next day, 10 of these mice were injected with 100 ml of the extract obtained in Preparation Example 1. The extract is used as a rat control group not administered. Cell growth is calculated for three weeks after administration of the extract. The number of cells in the control group is significantly increased while the increase in tumor cells in the experimental group is significantly suppressed.

Experimental Example 2

NUGC-4 from cancer is injected subcutaneously into 20 rats. From the next day, 100 rats of these rats were injected daily with 500 mg / ml of the extract obtained in Preparation Example 1. Mice not administered the extract were used as controls. The growth of cells after administration of the extract is calculated for one month. After one month, the cells in the control group increased markedly, and there was some cooking area, and some animals died, but the number of cells in the test tube was significantly suppressed, and no animals died.

Claims (10)

The present invention is an antiviral agent consisting of sesame seeds (Sasamum indicum L.) unsaturated fatty acid and potato (Patato) alkali extract The antiviral agent according to claim 1, wherein the sesame seed oil fruit is used as an active ingredient of heat-extracted unsaturated fatty acid and potato alkali extract. The antiviral agent according to claim 1 or 2, wherein the virus is human immunodeficiency virus (HIV). The unsaturated fatty acid component according to claim 1 or 2 is palmitic acid, stearic acid, sasamin 0.4-1.1%, sesamolin 0.3-0.6%, sesamol ) Alkali extract component is one of vitamin (Vitamins) B1 (Thia-mine) 0.04mg B2 (Ribo-favin) 0.04mg Niacim 0.4mg C (Asodrbic acid) 99mg. The present invention is an anticancer agent consisting of EC as sesame, unsaturated fatty acid and alkali extract of potato as an active ingredient. [Claim 6] The anticancer agent according to claim 5, wherein the unsaturated fatty acid and the alkaline extract extracted after heat compression compression of sesame and potatoes are used as an active ingredient. The unsaturated fatty acid component according to claim 5 or 6 is palmitic acid, stearic acid, oleic acid, linoleic acid, antioxidant sesamin 0.4 to 1.1. %, Sesamolin 0.3 ~ 0.6%, Sesamol Potato Ingredients: Vitamin (Vitamins), B1 (Thia-mime) 0.04mg, B2 (Ribo-favin) 0.04mg, Niacin 0.4mg, C (Asodrbic acid) 99mg, unsaturated fatty acid, an anticancer agent characterized in that the alkali extract The present invention is a method for producing an antiviral agent by mixing sesame seed with 15% moisture and drying it in an e-zen container, heating and compressing it without burning, and mixing the unsaturated fatty acid in the compressed extract alkaline solution in a 1: 1 manner. The unsaturated fatty acid component according to claim 8 is palmitic acid, stearic acid, oleic acid linoleic acid, antioxidant sasamin 0.4-1.1%, sesamolin ) 0.3 ~ 0.6%, Sesamol potato component is Vitamin EC in Vitamin (Vitamins) B1 (Thia-mine) 0.04mg B2 (Ribo-favin) 0.04mg Niacim 0.4mg C (Asodrbic acid) 99mg Method for producing an antiviral agent, characterized in that made. The present invention is a method for producing an anticancer agent by mixing sesame extract with 1: 1 in a microwave oven, dried in a microwave oven, heat-pressed and put into a microwave oven in a sterilized manner.