KR20000069346A - 의약용 항산화제로서 사용하기 위한 17α-디하이드로에퀼레닌 - Google Patents

의약용 항산화제로서 사용하기 위한 17α-디하이드로에퀼레닌 Download PDF

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Publication number
KR20000069346A
KR20000069346A KR1019997005048A KR19997005048A KR20000069346A KR 20000069346 A KR20000069346 A KR 20000069346A KR 1019997005048 A KR1019997005048 A KR 1019997005048A KR 19997005048 A KR19997005048 A KR 19997005048A KR 20000069346 A KR20000069346 A KR 20000069346A
Authority
KR
South Korea
Prior art keywords
dihydroequilenin
disease
free radical
salt
pharmaceutically acceptable
Prior art date
Application number
KR1019997005048A
Other languages
English (en)
Korean (ko)
Inventor
아델먼스티븐제이
프로지알렉도로씨헬렌
클락도날드유진
Original Assignee
이곤 이 버그
아메리칸 홈 푸로닥츠 코포레이션
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 이곤 이 버그, 아메리칸 홈 푸로닥츠 코포레이션 filed Critical 이곤 이 버그
Publication of KR20000069346A publication Critical patent/KR20000069346A/ko

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/5685Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1019997005048A 1996-12-09 1997-12-05 의약용 항산화제로서 사용하기 위한 17α-디하이드로에퀼레닌 KR20000069346A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US76263496A 1996-12-09 1996-12-09
US8/762,634 1996-12-09

Publications (1)

Publication Number Publication Date
KR20000069346A true KR20000069346A (ko) 2000-11-25

Family

ID=25065657

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019997005048A KR20000069346A (ko) 1996-12-09 1997-12-05 의약용 항산화제로서 사용하기 위한 17α-디하이드로에퀼레닌

Country Status (13)

Country Link
EP (1) EP0946182A1 (xx)
JP (1) JP2001506629A (xx)
KR (1) KR20000069346A (xx)
CN (1) CN1239890A (xx)
AR (1) AR010336A1 (xx)
AU (1) AU743519B2 (xx)
BR (1) BR9714382A (xx)
CA (1) CA2272089A1 (xx)
HU (1) HUP0000570A3 (xx)
IL (1) IL130069A0 (xx)
NZ (1) NZ336341A (xx)
WO (1) WO1998025627A1 (xx)
ZA (1) ZA9711053B (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6271221B1 (en) * 1996-12-10 2001-08-07 American Home Products Corporation Use of equilenin as an antioxidant
DE10154221A1 (de) * 2001-11-07 2003-05-15 Max Delbrueck Centrum Mittel zur Behandlung von Läsionen des Nervensystems

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4338314C1 (de) * 1993-11-10 1995-03-30 Jenapharm Gmbh Pharmazeutische Präparate zur Prophylaxe und Therapie radikalvermittelter Zellschädigungen

Also Published As

Publication number Publication date
JP2001506629A (ja) 2001-05-22
ZA9711053B (en) 1999-06-09
IL130069A0 (en) 2000-02-29
EP0946182A1 (en) 1999-10-06
BR9714382A (pt) 2000-05-16
CN1239890A (zh) 1999-12-29
AR010336A1 (es) 2000-06-07
AU743519B2 (en) 2002-01-31
AU5464498A (en) 1998-07-03
CA2272089A1 (en) 1998-06-18
HUP0000570A2 (hu) 2000-10-28
WO1998025627A1 (en) 1998-06-18
NZ336341A (en) 2002-02-01
HUP0000570A3 (en) 2000-12-28

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Legal Events

Date Code Title Description
A201 Request for examination
E902 Notification of reason for refusal
E601 Decision to refuse application