KR102854980B1 - 약독화 표현형의 범위를 제공하는 m2-2 orf 변이를 가지는 재조합 호흡기 세포융합 바이러스 균주 - Google Patents

약독화 표현형의 범위를 제공하는 m2-2 orf 변이를 가지는 재조합 호흡기 세포융합 바이러스 균주

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KR102854980B1
KR102854980B1 KR1020187019759A KR20187019759A KR102854980B1 KR 102854980 B1 KR102854980 B1 KR 102854980B1 KR 1020187019759 A KR1020187019759 A KR 1020187019759A KR 20187019759 A KR20187019759 A KR 20187019759A KR 102854980 B1 KR102854980 B1 KR 102854980B1
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respiratory syncytial
syncytial virus
rsv
seq
protein
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KR20180085803A (ko
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피터 엘. 콜린스
우르술라 제이. 부흐홀츠
신디 루온고
Original Assignee
더 유나이티드 스테이츠 오브 어메리카, 애즈 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈
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Application filed by 더 유나이티드 스테이츠 오브 어메리카, 애즈 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈 filed Critical 더 유나이티드 스테이츠 오브 어메리카, 애즈 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈
Priority to KR1020257029082A priority Critical patent/KR20250134719A/ko
Publication of KR20180085803A publication Critical patent/KR20180085803A/ko
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KR1020187019759A 2015-12-11 2016-12-12 약독화 표현형의 범위를 제공하는 m2-2 orf 변이를 가지는 재조합 호흡기 세포융합 바이러스 균주 Active KR102854980B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020257029082A KR20250134719A (ko) 2015-12-11 2016-12-12 약독화 표현형의 범위를 제공하는 m2-2 orf 변이를 가지는 재조합 호흡기 세포융합 바이러스 균주

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562266199P 2015-12-11 2015-12-11
US62/266,199 2015-12-11
PCT/US2016/066146 WO2017100759A1 (en) 2015-12-11 2016-12-12 Recombinant respiratory syncytial virus strains with mutations in the m2-2 orf providing a range of attenuation phenotypes

Related Child Applications (1)

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KR1020257029082A Division KR20250134719A (ko) 2015-12-11 2016-12-12 약독화 표현형의 범위를 제공하는 m2-2 orf 변이를 가지는 재조합 호흡기 세포융합 바이러스 균주

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KR20180085803A KR20180085803A (ko) 2018-07-27
KR102854980B1 true KR102854980B1 (ko) 2025-09-03

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KR1020187019759A Active KR102854980B1 (ko) 2015-12-11 2016-12-12 약독화 표현형의 범위를 제공하는 m2-2 orf 변이를 가지는 재조합 호흡기 세포융합 바이러스 균주
KR1020257029082A Pending KR20250134719A (ko) 2015-12-11 2016-12-12 약독화 표현형의 범위를 제공하는 m2-2 orf 변이를 가지는 재조합 호흡기 세포융합 바이러스 균주

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EP (1) EP3386539A1 (enExample)
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CN (1) CN109310752B (enExample)
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EP3630173A1 (en) * 2017-05-29 2020-04-08 The United States of America, as represented by the Secretary, Department of Health and Human Services Recombinant chimeric bovine/human parainfluenza virus 3 expressing rsv g and its use
US20230279362A1 (en) * 2020-06-05 2023-09-07 The United States Of America, As Represented By The Secretary, Department Of Health And Human Live attenuated respiratory syncytial virus
AU2024380679A1 (en) 2023-11-17 2026-07-02 Sanofi Vaccines US Inc. Trehalose vaccine formulation

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DE3224404A1 (de) 1982-06-30 1984-01-05 LuK Lamellen und Kupplungsbau GmbH, 7580 Bühl Reibungskupplung sowie verfahren zu deren montage
US7465574B2 (en) 1994-09-30 2008-12-16 Medimmune, Llc Recombinant RSV virus expression systems and vaccines
US6264957B1 (en) 1995-09-27 2001-07-24 The United States Of America As Represented By The Department Of Health And Human Services Product of infectious respiratory syncytial virus from cloned nucleotide sequences
US6713066B1 (en) 1996-07-15 2004-03-30 The United States Of America As Represented By The Department Of Health And Human Services Production of attenuated respiratory syncytial virus vaccines involving modification of M2 ORF2
US20040005542A1 (en) * 2001-06-22 2004-01-08 Krempl Christine D Respiratory syncytial virus vaccines expressing protective antigens from promotor- proximal genes
WO2002044334A2 (en) * 2000-11-28 2002-06-06 Aviron, Inc. Recombinant rsv virus expression systems and vaccines
DE10118446A1 (de) * 2001-04-12 2002-10-17 Thomas Hartung Prüfverfahren zur Untersuchung fließfähiger Medien auf Gehalte an mikrobiellen Toxinen
PL3511015T3 (pl) 2012-04-13 2021-09-13 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Genetycznie stabilna żywa atenuowana szczepionka przeciw syncytialnemu wirusowi oddechowemu i jej wytwarzanie
WO2015041924A2 (en) * 2013-09-18 2015-03-26 Medimmune, Llc Recombinant respiratory syncytial virus (rsv) and caccines
US10947512B2 (en) 2015-08-14 2021-03-16 Research Institute At Nationwide Children's Hospital Respiratory syncytial virus having altered NS1 protein function and related materials and methods

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SCIENCE TRANSLATIONAL MEDICINE, 2015.11.04., vol. 7, no. 312, pp. 1-9.*

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RU2018125246A3 (enExample) 2020-05-25
CN109310752B (zh) 2022-12-16
BR112018011674A2 (pt) 2018-12-04
US20190040365A1 (en) 2019-02-07
US11332721B2 (en) 2022-05-17
AR106956A1 (es) 2018-03-07
JP2018536428A (ja) 2018-12-13
JP7079197B2 (ja) 2022-06-01
US20200283740A1 (en) 2020-09-10
CN109310752A (zh) 2019-02-05
JP7357709B2 (ja) 2023-10-06
RU2018125246A (ru) 2020-01-15
KR20180085803A (ko) 2018-07-27
KR20250134719A (ko) 2025-09-11
CA3007408A1 (en) 2017-06-15
WO2017100759A1 (en) 2017-06-15
AU2016366771B2 (en) 2022-04-07
EP3386539A1 (en) 2018-10-17
AU2016366771A1 (en) 2018-07-12
JP2022088376A (ja) 2022-06-14
US10655109B2 (en) 2020-05-19

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