KR102827626B1 - 멜록시캄을 포함하는 약학 조성물 - Google Patents

멜록시캄을 포함하는 약학 조성물 Download PDF

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Publication number
KR102827626B1
KR102827626B1 KR1020237021609A KR20237021609A KR102827626B1 KR 102827626 B1 KR102827626 B1 KR 102827626B1 KR 1020237021609 A KR1020237021609 A KR 1020237021609A KR 20237021609 A KR20237021609 A KR 20237021609A KR 102827626 B1 KR102827626 B1 KR 102827626B1
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South Korea
Prior art keywords
meloxicam
cyclodextrin
pharmaceutical composition
solid pharmaceutical
pain
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KR1020237021609A
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Korean (ko)
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KR20230098923A (ko
Inventor
에리오 타뷔토
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액섬 테라퓨틱스, 인크.
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=60389519&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR102827626(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 액섬 테라퓨틱스, 인크. filed Critical 액섬 테라퓨틱스, 인크.
Priority to KR1020257021329A priority Critical patent/KR20250099425A/ko
Publication of KR20230098923A publication Critical patent/KR20230098923A/ko
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/724Cyclodextrins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cosmetics (AREA)
KR1020237021609A 2015-02-10 2016-04-11 멜록시캄을 포함하는 약학 조성물 Active KR102827626B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020257021329A KR20250099425A (ko) 2015-02-10 2016-04-11 멜록시캄을 포함하는 약학 조성물

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201562114215P 2015-02-10 2015-02-10
US62/114,215 2015-02-10
US201562259993P 2015-11-25 2015-11-25
US62/259,993 2015-11-25
PCT/US2016/026991 WO2016131067A2 (en) 2015-02-10 2016-04-11 Pharmaceutical compositions comprising meloxicam
KR1020237007407A KR102550497B1 (ko) 2015-02-10 2016-04-11 멜록시캄을 포함하는 약학 조성물

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020237007407A Division KR102550497B1 (ko) 2015-02-10 2016-04-11 멜록시캄을 포함하는 약학 조성물

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020257021329A Division KR20250099425A (ko) 2015-02-10 2016-04-11 멜록시캄을 포함하는 약학 조성물

Publications (2)

Publication Number Publication Date
KR20230098923A KR20230098923A (ko) 2023-07-04
KR102827626B1 true KR102827626B1 (ko) 2025-06-30

Family

ID=60389519

Family Applications (9)

Application Number Title Priority Date Filing Date
KR1020237021609A Active KR102827626B1 (ko) 2015-02-10 2016-04-11 멜록시캄을 포함하는 약학 조성물
KR1020257021329A Pending KR20250099425A (ko) 2015-02-10 2016-04-11 멜록시캄을 포함하는 약학 조성물
KR1020227038441A Active KR102507663B1 (ko) 2015-02-10 2016-04-11 멜록시캄을 포함하는 약학 조성물
KR1020227024833A Active KR102465027B1 (ko) 2015-02-10 2016-04-11 멜록시캄을 포함하는 약학 조성물
KR1020217027341A Active KR102429352B1 (ko) 2015-11-25 2016-04-11 멜록시캄을 포함하는 약학 조성물
KR1020227026291A Active KR102447080B1 (ko) 2015-11-25 2016-04-11 멜록시캄을 포함하는 약학 조성물
KR1020177025448A Active KR102163404B1 (ko) 2015-02-10 2016-04-11 멜록시캄을 포함하는 약학 조성물
KR1020237007407A Active KR102550497B1 (ko) 2015-02-10 2016-04-11 멜록시캄을 포함하는 약학 조성물
KR1020207028181A Active KR102424013B1 (ko) 2015-02-10 2016-04-11 멜록시캄을 포함하는 약학 조성물

Family Applications After (8)

Application Number Title Priority Date Filing Date
KR1020257021329A Pending KR20250099425A (ko) 2015-02-10 2016-04-11 멜록시캄을 포함하는 약학 조성물
KR1020227038441A Active KR102507663B1 (ko) 2015-02-10 2016-04-11 멜록시캄을 포함하는 약학 조성물
KR1020227024833A Active KR102465027B1 (ko) 2015-02-10 2016-04-11 멜록시캄을 포함하는 약학 조성물
KR1020217027341A Active KR102429352B1 (ko) 2015-11-25 2016-04-11 멜록시캄을 포함하는 약학 조성물
KR1020227026291A Active KR102447080B1 (ko) 2015-11-25 2016-04-11 멜록시캄을 포함하는 약학 조성물
KR1020177025448A Active KR102163404B1 (ko) 2015-02-10 2016-04-11 멜록시캄을 포함하는 약학 조성물
KR1020237007407A Active KR102550497B1 (ko) 2015-02-10 2016-04-11 멜록시캄을 포함하는 약학 조성물
KR1020207028181A Active KR102424013B1 (ko) 2015-02-10 2016-04-11 멜록시캄을 포함하는 약학 조성물

Country Status (22)

Country Link
EP (3) EP4470614A3 (https=)
JP (6) JP6746612B2 (https=)
KR (9) KR102827626B1 (https=)
CN (2) CN113144218A (https=)
AU (4) AU2016218992C1 (https=)
CA (4) CA3278634A1 (https=)
CY (1) CY1125193T1 (https=)
DK (1) DK3256138T3 (https=)
ES (1) ES2913288T3 (https=)
HU (1) HUE058677T2 (https=)
IL (3) IL316648A (https=)
LT (1) LT3256138T (https=)
MX (2) MX380762B (https=)
MY (1) MY191574A (https=)
NZ (1) NZ734233A (https=)
PL (1) PL3256138T3 (https=)
PT (1) PT3256138T (https=)
RS (1) RS63260B1 (https=)
SG (2) SG11201706123XA (https=)
SI (1) SI3256138T1 (https=)
SM (1) SMT202200194T1 (https=)
WO (1) WO2016131067A2 (https=)

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