KR102798514B1 - Dux4의 발현을 조절하기 위한 화합물, 방법 및 의약조성물 - Google Patents

Dux4의 발현을 조절하기 위한 화합물, 방법 및 의약조성물 Download PDF

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KR102798514B1
KR102798514B1 KR1020217033941A KR20217033941A KR102798514B1 KR 102798514 B1 KR102798514 B1 KR 102798514B1 KR 1020217033941 A KR1020217033941 A KR 1020217033941A KR 20217033941 A KR20217033941 A KR 20217033941A KR 102798514 B1 KR102798514 B1 KR 102798514B1
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residues
modified
nucleoside
dux4
nucleic acid
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KR20210142699A (ko
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신지 구마가이
다카시 야시로
도모 아라키
다카유키 가나가와
지에코 오카가키
히로유키 후루카와
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미쓰비시 타나베 파마 코퍼레이션
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KR1020217033941A 2019-03-29 2020-03-27 Dux4의 발현을 조절하기 위한 화합물, 방법 및 의약조성물 Active KR102798514B1 (ko)

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JPJP-P-2019-067914 2019-03-29
JP2019067914 2019-03-29
PCT/JP2020/014307 WO2020203880A1 (ja) 2019-03-29 2020-03-27 Ｄｕｘ４の発現を調節するための化合物、方法及び医薬組成物

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KR20210142699A KR20210142699A (ko) 2021-11-25
KR102798514B1 true KR102798514B1 (ko) 2025-04-18

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US (1) US20220228140A1 (https=)
EP (1) EP3950006A4 (https=)
JP (2) JP7667074B2 (https=)
KR (1) KR102798514B1 (https=)
CN (3) CN120290561A (https=)
AR (1) AR118513A1 (https=)
AU (1) AU2020252710B8 (https=)
BR (1) BR112021018793A2 (https=)
CA (4) CA3135579A1 (https=)
IL (1) IL286733A (https=)
MX (1) MX2021011921A (https=)
PH (1) PH12021552257A1 (https=)
SG (1) SG11202110674XA (https=)
TW (1) TW202104595A (https=)
WO (1) WO2020203880A1 (https=)

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US11555190B2 (en) 2020-03-19 2023-01-17 Avidity Biosciences, Inc. Compositions and methods of treating Facioscapulohumeral muscular dystrophy
CA3174286A1 (en) 2020-04-02 2021-10-07 Robert PLACE Targeted inhibition using engineered oligonucleotides
EP4252846A4 (en) * 2020-11-06 2025-12-03 Sumitomo Pharma Co Ltd REGULATOR FOR THE EXPRESSION AND/OR FUNCTION OF THE RPS25 GENE
US20240336915A1 (en) * 2021-01-22 2024-10-10 Ionis Pharmaceuticals, Inc. Compounds and methods for reducing dux4 expression
MX2024003266A (es) 2021-09-16 2024-04-03 Avidity Biosciences Inc Composiciones y metodos de tratamiento de la distrofia muscular facioescapulohumeral.
CN120418261A (zh) 2022-12-21 2025-08-01 田边三菱制药株式会社 制造中间体的制造方法、该制造中间体及使用其的桥连型人工核酸中间体的制造方法

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