KR102780121B1 - 면역 결핍 및 자가면역 질환을 치료하기 위한 조혈모세포에서 foxp3 을 발현하는 렌티바이러스 벡터 - Google Patents

면역 결핍 및 자가면역 질환을 치료하기 위한 조혈모세포에서 foxp3 을 발현하는 렌티바이러스 벡터 Download PDF

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KR102780121B1
KR102780121B1 KR1020207008314A KR20207008314A KR102780121B1 KR 102780121 B1 KR102780121 B1 KR 102780121B1 KR 1020207008314 A KR1020207008314 A KR 1020207008314A KR 20207008314 A KR20207008314 A KR 20207008314A KR 102780121 B1 KR102780121 B1 KR 102780121B1
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foxp3
cells
vector
expression
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도날드 비 콘
마리아 그라치아 론카롤로
로저 피 홀리스
케이틀린 이 메지우크
로사 베체타
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더 리전트 오브 더 유니버시티 오브 캘리포니아
더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티
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KR1020207008314A 2017-08-22 2018-08-22 면역 결핍 및 자가면역 질환을 치료하기 위한 조혈모세포에서 foxp3 을 발현하는 렌티바이러스 벡터 Active KR102780121B1 (ko)

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US201762548891P 2017-08-22 2017-08-22
US62/548,891 2017-08-22
PCT/US2018/047586 WO2019040655A1 (en) 2017-08-22 2018-08-22 LENTIVIRAL VECTORS EXPRESSING FOXP3 IN HEMATOPOIETIC STEM CELLS TO TREAT IMMUNITY DEFICIENCIES AND AUTOIMMUNE DISEASES

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KR102780121B1 true KR102780121B1 (ko) 2025-03-12

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EP (1) EP3672617A4 (https=)
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Families Citing this family (11)

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Publication number Priority date Publication date Assignee Title
CN110139675B (zh) 2016-10-31 2023-09-29 西雅图儿童医院（Dba西雅图儿童研究所） 用具有工程化稳定的内源性foxp3基因表达的cd4t细胞治疗自身免疫疾病的方法
EP3672617A4 (en) 2017-08-22 2021-06-23 The Regents of the University of California LENTIVIRAL VECTORS EXPRESSING FOXP3 IN HEMATOPOIETIC STEM CELLS TO TREAT IMMUNITY DEFICIENCIES AND AUTOIMMUNE DISEASES
US11713459B2 (en) 2018-04-27 2023-08-01 Seattle Children's Hospital Expression of FOXP3 in edited CD34+ cells
CA3091491A1 (en) * 2018-04-27 2019-10-31 Seattle Children's Hospital (dba Seattle Children's Research Institute) Expression of human foxp3 in gene edited t cells
US20220168394A1 (en) * 2019-04-23 2022-06-02 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods of inducing or restoring immune tolerance
CA3140910A1 (en) * 2019-06-07 2020-12-10 The Board Of Trustees Of The Leland Stanford Junior University Foxp3 engineered cd4+ t cells for use in treg-based immunotherapy
WO2021028359A1 (en) * 2019-08-09 2021-02-18 Sangamo Therapeutics France Controlled expression of chimeric antigen receptors in t cells
US20240400993A1 (en) * 2021-09-27 2024-12-05 Kyoto University Method for producing t cell
EP4474476A4 (en) * 2022-02-04 2026-02-18 Univ Kyoto T-LYMPHOCYTE PRODUCTION PROCESS
US20250230411A1 (en) * 2022-03-23 2025-07-17 Kyoto University Method for producing regulatory t cells
JPWO2024071010A1 (https=) * 2022-09-26 2024-04-04

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US7507542B2 (en) 2001-05-08 2009-03-24 Ucb Sa Method for regulating immune function using the FOXP3 protein
JP2004208548A (ja) 2002-12-27 2004-07-29 Institute Of Physical & Chemical Research 免疫反応の抗原特異的抑制
US8158596B2 (en) * 2007-05-11 2012-04-17 The Regents Of The University Of Michigan Materials and methods for FOXP3 tumor suppression
US20140065110A1 (en) * 2012-08-31 2014-03-06 The Regents Of The University Of California Genetically modified msc and therapeutic methods
US9663564B2 (en) * 2013-03-15 2017-05-30 The Regents Of The University Of California Vectors and methods to treat ischemia
WO2014121840A1 (en) * 2013-02-07 2014-08-14 Medizinische Hochschule Hannover Induced dendritic cells and uses thereof
GB201318347D0 (en) * 2013-10-16 2013-11-27 Ucl Business Plc Retroviral vectors
EP3307887A1 (en) 2015-06-09 2018-04-18 Editas Medicine, Inc. Crispr/cas-related methods and compositions for improving transplantation
EP3672617A4 (en) 2017-08-22 2021-06-23 The Regents of the University of California LENTIVIRAL VECTORS EXPRESSING FOXP3 IN HEMATOPOIETIC STEM CELLS TO TREAT IMMUNITY DEFICIENCIES AND AUTOIMMUNE DISEASES

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Science, Vol.341, No.6148, pp.1233151(2013.07.11.)*

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KR20200054210A (ko) 2020-05-19
EP3672617A4 (en) 2021-06-23
JP7290288B2 (ja) 2023-06-13
WO2019040655A1 (en) 2019-02-28
EP3672617A1 (en) 2020-07-01
US20200347404A1 (en) 2020-11-05
US12060566B2 (en) 2024-08-13
JP2020533969A (ja) 2020-11-26
US20240336935A1 (en) 2024-10-10

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