KR102777370B1 - 돌연변이된 ras에 대한 hla 클래스 ii-제한된 t 세포 수용체 - Google Patents

돌연변이된 ras에 대한 hla 클래스 ii-제한된 t 세포 수용체 Download PDF

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KR102777370B1
KR102777370B1 KR1020207011112A KR20207011112A KR102777370B1 KR 102777370 B1 KR102777370 B1 KR 102777370B1 KR 1020207011112 A KR1020207011112 A KR 1020207011112A KR 20207011112 A KR20207011112 A KR 20207011112A KR 102777370 B1 KR102777370 B1 KR 102777370B1
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라미 요세프
갤 카프리
폴 에프 로빈스
스티븐 에이 로젠버그
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더 유나이티드 스테이츠 오브 어메리카, 애즈 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈
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KR1020207011112A 2017-09-20 2018-09-19 돌연변이된 ras에 대한 hla 클래스 ii-제한된 t 세포 수용체 Active KR102777370B1 (ko)

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KR1020257006999A KR20250037592A (ko) 2017-09-20 2018-09-19 돌연변이된 ras에 대한 hla 클래스 ii-제한된 t 세포 수용체

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US201762560930P 2017-09-20 2017-09-20
US62/560,930 2017-09-20
PCT/US2018/051641 WO2019060349A1 (en) 2017-09-20 2018-09-19 CLASS II HLA RESTRICTED T LYMPHOCYTE RECEPTORS AGAINST KRAS MUTATED

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KR1020257006999A Pending KR20250037592A (ko) 2017-09-20 2018-09-19 돌연변이된 ras에 대한 hla 클래스 ii-제한된 t 세포 수용체

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CN112759641B (zh) * 2019-11-01 2023-01-20 香雪生命科学技术（广东）有限公司 一种识别Kras G12V的高亲和力TCR
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AU2021220957A1 (en) * 2020-02-14 2022-09-01 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services HLA class I-restricted T cell receptors against ras with G12V mutation
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TWI900533B (zh) * 2020-02-26 2025-10-11 美國衛生與公眾服務部 針對含有ｇ１２ｖ突變之ｒａｓ之ｈｌａ第ｉｉ類限制性ｔ細胞受體
WO2021262829A2 (en) * 2020-06-24 2021-12-30 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Hla class i-restricted t cell receptors against cd20
WO2022015694A1 (en) * 2020-07-13 2022-01-20 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Hla class ii–restricted drb t cell receptors against ras with g12d mutation
CN116348484A (zh) * 2020-07-16 2023-06-27 美国卫生和人力服务部 针对含有g12v突变的ras的hla-ii类限制性drb t细胞受体
CN112300269B (zh) * 2020-09-29 2022-12-09 中国科学院微生物研究所 Kras突变特异性t细胞受体筛选及抗肿瘤用途
TW202540156A (zh) * 2020-10-02 2025-10-16 美國衛生與公眾服務部 針對含有g13d突變之ras之hla第ii類限制性dq t細胞受體
US20240000834A1 (en) * 2020-11-24 2024-01-04 Shanghai GenBase Biotechnology Co., Ltd. Ras mutant epitope peptide and t cell receptor recognizing ras mutant
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CN117264043B (zh) * 2022-06-14 2024-05-10 上海镔铁生物科技有限责任公司 靶向kras g12v突变多肽的t细胞受体及其用途
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WO2026019786A1 (en) * 2024-07-16 2026-01-22 Board Of Regents, The University Of Texas System Peptides and engineered t cell receptors targeting brachyury antigen and methods of use
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MA50180A (fr) 2021-05-26
TWI825029B (zh) 2023-12-11
CN120082603A (zh) 2025-06-03
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WO2019060349A1 (en) 2019-03-28
BR112020005469A2 (pt) 2020-09-29
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KR20200051804A (ko) 2020-05-13
US20220204584A1 (en) 2022-06-30
MX2024004610A (es) 2024-04-30
CN111201237B (zh) 2025-03-25
AU2018335274B2 (en) 2025-02-13
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AU2025202532A9 (en) 2025-09-04
TW201920251A (zh) 2019-06-01
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