KR102716959B1 - 신경변성 장애의 치료 방법 - Google Patents

신경변성 장애의 치료 방법 Download PDF

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Publication number
KR102716959B1
KR102716959B1 KR1020217005803A KR20217005803A KR102716959B1 KR 102716959 B1 KR102716959 B1 KR 102716959B1 KR 1020217005803 A KR1020217005803 A KR 1020217005803A KR 20217005803 A KR20217005803 A KR 20217005803A KR 102716959 B1 KR102716959 B1 KR 102716959B1
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KR
South Korea
Prior art keywords
spa
subject
csf
tramiprosate
disease
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KR1020217005803A
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English (en)
Korean (ko)
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KR20210039415A (ko
Inventor
존 헤이
페트레 코시스
마틴 톨라
닐 윌리엄 플란츠라이히
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알제온, 인크.
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/145Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
KR1020217005803A 2018-08-01 2019-07-30 신경변성 장애의 치료 방법 Active KR102716959B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862713061P 2018-08-01 2018-08-01
US62/713,061 2018-08-01
PCT/US2019/044023 WO2020028290A1 (en) 2018-08-01 2019-07-30 Methods for treating neurodegenerative disorders

Publications (2)

Publication Number Publication Date
KR20210039415A KR20210039415A (ko) 2021-04-09
KR102716959B1 true KR102716959B1 (ko) 2024-10-11

Family

ID=67614642

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020217005803A Active KR102716959B1 (ko) 2018-08-01 2019-07-30 신경변성 장애의 치료 방법

Country Status (27)

Country Link
US (2) US12083082B2 (https=)
EP (1) EP3829563B1 (https=)
JP (1) JP7573512B2 (https=)
KR (1) KR102716959B1 (https=)
CN (1) CN112867485A (https=)
AU (1) AU2019315853B2 (https=)
BR (1) BR112021001739A2 (https=)
CL (1) CL2021000269A1 (https=)
DK (1) DK3829563T3 (https=)
EA (1) EA202190406A1 (https=)
ES (1) ES3011716T3 (https=)
FI (1) FI3829563T3 (https=)
HR (1) HRP20250206T1 (https=)
HU (1) HUE070101T2 (https=)
IL (1) IL280424B2 (https=)
LT (1) LT3829563T (https=)
MX (1) MX2021001287A (https=)
MY (1) MY206530A (https=)
PH (1) PH12021550213A1 (https=)
PL (1) PL3829563T3 (https=)
PT (1) PT3829563T (https=)
RS (1) RS66516B1 (https=)
SG (1) SG11202100767XA (https=)
SI (1) SI3829563T1 (https=)
SM (1) SMT202500080T1 (https=)
UA (1) UA130011C2 (https=)
WO (1) WO2020028290A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112021025504A2 (pt) * 2019-06-17 2022-04-26 Alzheon Inc Métodos para tratar distúrbios neurodegenerativos
MX2024007070A (es) * 2021-12-09 2024-08-22 Alzheon Inc Alz-801 para uso en el tratamiento de la enfermedad de alzheimer.

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017044840A1 (en) 2015-09-10 2017-03-16 Alzheon, Inc. Methods of treating neurodegenerative disorders in a particular patient population

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840294A (en) 1993-03-29 1998-11-24 Queen's University At Kingston Method for treating amyloidosis
PT2089417E (pt) 2006-10-12 2015-04-14 Bhi Ltd Partnership Métodos, compostos, composições e veículos para administrar o ácido 3-amino-1-propanossulfónico
WO2013177367A2 (en) 2012-05-23 2013-11-28 The Johns Hopkins University Compounds and methods of use thereof for treating neurodegenerative disorders
WO2014121083A1 (en) 2013-01-31 2014-08-07 President And Fellows Of Harvard College Methods of increasing neuronal connectivity and/or treating a neurodegenerative condition
CA2941415A1 (en) * 2014-03-21 2015-09-24 Alzheon, Inc. Methods for treating neurological disorders

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017044840A1 (en) 2015-09-10 2017-03-16 Alzheon, Inc. Methods of treating neurodegenerative disorders in a particular patient population

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
The Journal of Prevention of Alzheimer's disease 4(3):149-156 (2017)

Also Published As

Publication number Publication date
PH12021550213A1 (en) 2021-11-03
CA3108150A1 (en) 2020-02-06
US12083082B2 (en) 2024-09-10
CN112867485A (zh) 2021-05-28
FI3829563T3 (fi) 2025-02-17
AU2019315853B2 (en) 2025-05-01
EA202190406A1 (ru) 2021-10-15
MX2021001287A (es) 2021-07-15
JP2021533128A (ja) 2021-12-02
PT3829563T (pt) 2025-02-18
US20210315847A1 (en) 2021-10-14
SG11202100767XA (en) 2021-02-25
HUE070101T2 (hu) 2025-05-28
IL280424A (en) 2021-03-01
US20250213507A1 (en) 2025-07-03
KR20210039415A (ko) 2021-04-09
MY206530A (en) 2024-12-19
CL2021000269A1 (es) 2021-06-18
SI3829563T1 (sl) 2025-05-30
ES3011716T3 (en) 2025-04-08
EP3829563B1 (en) 2024-11-20
UA130011C2 (uk) 2025-10-15
BR112021001739A2 (pt) 2021-04-27
IL280424B1 (en) 2024-09-01
RS66516B1 (sr) 2025-03-31
IL280424B2 (en) 2025-01-01
HRP20250206T1 (hr) 2025-04-11
PL3829563T3 (pl) 2025-04-07
AU2019315853A1 (en) 2021-03-18
WO2020028290A1 (en) 2020-02-06
DK3829563T3 (en) 2025-02-24
LT3829563T (lt) 2025-02-25
EP3829563A1 (en) 2021-06-09
JP7573512B2 (ja) 2024-10-25
SMT202500080T1 (it) 2025-03-12

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