KR102664751B1 - Cosmetic composition in freeze-dried formulation containing spicules and method for producing the same - Google Patents

Abstract

The present invention relates to a cosmetic composition in a freeze-dried formulation containing spicules and a method for producing the same. In particular, the liquid mixture containing spicules is freeze-dried to facilitate storage and use, and the spicules are easily dried during the freeze-drying process. It relates to a cosmetic composition in a freeze-dried formulation containing spicules with an improved freeze-drying method to reduce damage and a method for manufacturing the same.

Description

Cosmetic composition in freeze-dried formulation containing spicules and method for producing the same}

The present invention relates to a cosmetic composition in a freeze-dried formulation containing spicules and a method for producing the same. In particular, the liquid mixture containing spicules is freeze-dried to facilitate storage and use, and the spicules are easily dried during the freeze-drying process. It relates to a cosmetic composition in a freeze-dried formulation containing spicules with an improved freeze-drying method to reduce damage and a method for manufacturing the same.

In general, spicule is one of the substances widely used in skin care. It is a fine structure that forms the skeleton of a sponge (Spongilla Lacustris). It is a natural composite material made up of calcium and silicate in the form of fine needles taken from seaweed or coral. am. The fibrous skeleton of sponges has the ability to absorb through capillary action and is used in various fields, including medical applications. For example, bone fragments from sponges contain antibiotics for the treatment of osteomyelitis and are used for the treatment and prevention of the disease.

Since spicules have a needle-shaped structure, they are particularly suitable for delivering active ingredients to the dermal layer of the skin, so much research has been conducted to apply them to cosmetic compositions. Through these studies, spicules have been shown to improve acne skin, reduce acne marks and shallow scars. It can be used for many purposes, including alleviating fine wrinkles, large pores, surface pigmentation, managing blemishes and freckles, and removing dead skin cells.

Meanwhile, cosmetic compositions are manufactured containing water-soluble and fat-soluble raw materials and various additives. Due to the influence of beauty water (moisture) contained in the product itself, there is a possibility of causing a significant decrease in the potency of bioactive substances even within the expiration date or the occurrence of microorganisms. There are problems such as the need to add preservatives harmful to the human body to suppress this. This problem was also present in existing cosmetic compositions containing spicules, and cosmetic compositions using freeze-drying methods emerged as a solution to this problem.

After manufacturing and selling moisture-excluding freeze-dried cosmetics, consumers hand-make them and apply them to the skin by re-dissolving them in beauty water or an aqueous-based activator mixed with various water-soluble ingredients. Due to the nature of the formulation, water-soluble polymers such as hyaluronic acid and collagen are used. It is generally manufactured by simple freeze-drying or by including these ingredients as active raw materials for functional cosmetics.

In this regard, Korean Patent Publication No. 10-1892055 has excellent stability of the active ingredient based on a three-dimensional structure using mushroom-derived polysaccharides and collagen, and completely dissolves in a small amount of aqueous solution, and foaming occurs when dissolved, thereby reducing the amount of active ingredient. A cosmetic composition containing freeze-dried balls exhibiting high skin absorption and penetration rates is disclosed.

However, in the case of spicules, they are not simply cosmetics applied to the skin, but have the characteristic of penetrating into the transdermal layer through a needle-shaped structure, so there is a problem that the size of spicules must be uniform and the structure must be prevented from being deformed by freeze-drying. And research is needed to solve these problems.

Korean Patent Publication No. 10-1892055

In order to solve the above problems, the present invention freeze-dries a liquid mixture containing spicules for easy storage and use, and improves the freeze-drying method to reduce damage to spicules during the freeze-drying process. A cosmetic composition in a freeze-dried formulation containing cul and a method for producing the same are provided.

The purpose is a spicule purification step of separating and purifying spicules; A liquid mixing step of preparing a liquid mixture by mixing the purified spicules, sodium hyaluronate, and algin; A freeze-drying step of filling the liquid mixture into a freeze-drying mold and then freeze-drying it to prepare a solid mixture; and a packaging step of packaging the solid mixture; This can be achieved by a method for producing a cosmetic composition of a freeze-dried formulation containing spicules, which includes.

Specifically, in the freeze-drying step, 10 parts by weight of a 70-90 volume% ethanol aqueous solution and 2 parts by weight of mineral oil are added to the liquid mixture relative to 100 parts by weight of the liquid mixture before filling the freeze-drying mold, and then heated to 50-60°C. It may further include the step of inducing emulsion by mixing.

Specifically, the liquid mixing step further includes adding 5 to 10 parts by weight of the fermentation mixture based on 100 parts by weight of the liquid mixture, and the fermentation mixture includes persimmon leaves, ginseng fruit, bokbunja seed oil, cacao nibs, purified water, and The Cheonggukguk bacteria culture may be ground and mixed at a weight ratio of 10: 20: 10: 15: 44: 1 and then fermented for 30 to 50 hours.

Specifically, the spicule purification step involves applying mineral oil to the spicules after purification, drying them with hot air at 230-250°C, applying a mixed oil of argan oil and ginkgo oil in a 1:1 weight ratio, and then naturally drying. It may additionally include.

In addition, the above object can be achieved by a cosmetic composition in a freeze-dried formulation containing spicules prepared by the above-mentioned production method.

The cosmetic composition of the freeze-dried formulation containing spicules according to the present invention is easy to store and use by freeze-drying the liquid mixture containing spicules. In order to reduce damage to spicules during the freeze-drying process, a freeze-drying method is used. has been improved, so it can be used as a cosmetic composition that has the efficacy of spicules and is easy to store for a long time.

Figure 1 is a flowchart illustrating a method of manufacturing a freeze-dried cosmetic composition containing spicules according to an embodiment.

Hereinafter, embodiments will be described in detail with reference to the attached drawings. However, various changes can be made to the embodiments, so the scope of the patent application is not limited or limited by these embodiments. It should be understood that all changes, equivalents, or substitutes for the embodiments are included in the scope of rights.

Specific structural or functional descriptions of the embodiments are disclosed for illustrative purposes only and may be modified and implemented in various forms. Accordingly, the embodiments are not limited to the specific disclosed form, and the scope of the present specification includes changes, equivalents, or substitutes included in the technical spirit.

Terms such as first or second may be used to describe various components, but these terms should be interpreted only for the purpose of distinguishing one component from another component. For example, a first component may be named a second component, and similarly, the second component may also be named a first component.

When a component is referred to as being “connected” to another component, it should be understood that it may be directly connected or connected to the other component, but that other components may exist in between.

The terms used in the examples are for descriptive purposes only and should not be construed as limiting. Singular expressions include plural expressions unless the context clearly dictates otherwise. In this specification, terms such as “comprise” or “have” are intended to designate the presence of features, numbers, steps, operations, components, parts, or combinations thereof described in the specification, but are not intended to indicate the presence of one or more other features. It should be understood that it does not exclude in advance the possibility of the existence or addition of elements, numbers, steps, operations, components, parts, or combinations thereof.

Unless otherwise defined, all terms used herein, including technical or scientific terms, have the same meaning as generally understood by a person of ordinary skill in the technical field to which the embodiments belong. Terms defined in commonly used dictionaries should be interpreted as having a meaning consistent with the meaning in the context of the related technology, and unless explicitly defined in the present application, should not be interpreted in an ideal or excessively formal sense. No.

The advantages and features of the present invention and methods for achieving them will become clear by referring to the embodiments described in detail below along with the accompanying drawings. However, the present invention is not limited to the embodiments disclosed below and will be implemented in various different forms. The present embodiments only serve to ensure that the disclosure of the present invention is complete and that common knowledge in the technical field to which the present invention pertains is not limited. It is provided to fully inform those who have the scope of the invention, and the present invention is only defined by the scope of the claims.

In the embodiments of the present invention, unless otherwise defined, all terms used herein, including technical or scientific terms, are the same as those commonly understood by a person of ordinary skill in the technical field to which the present invention pertains. It has meaning. Terms defined in commonly used dictionaries should be interpreted as having a meaning consistent with the meaning in the context of the related technology, and unless clearly defined in the embodiments of the present invention, have an ideal or excessively formal meaning. It is not interpreted as

The shapes, sizes, proportions, angles, numbers, etc. disclosed in the drawings for explaining embodiments of the present invention are illustrative, and the present invention is not limited to the matters shown. Additionally, in describing the present invention, if it is determined that a detailed description of related known technologies may unnecessarily obscure the gist of the present invention, the detailed description will be omitted. When 'includes', 'has', 'consists of', etc. mentioned in this specification are used, other parts may be added unless 'only' is used. When a component is expressed in the singular, the plural is included unless specifically stated otherwise.

When interpreting a component, it is interpreted to include the margin of error even if there is no separate explicit description.

The size and thickness of each component shown in the drawings are shown for convenience of explanation, and the present invention is not necessarily limited to the size and thickness of the components shown.

Each feature of the various embodiments of the present invention can be partially or fully combined or combined with each other, and as can be fully understood by those skilled in the art, various technical interconnections and operations are possible, and each embodiment may be implemented independently of each other. It may be possible to conduct them together due to a related relationship.

One aspect of the present application includes a spicule purification step of separating and purifying spicules; A liquid mixing step of preparing a liquid mixture by mixing the purified spicules, sodium hyaluronate, and algin; A freeze-drying step of filling the liquid mixture into a freeze-drying mold and then freeze-drying it to prepare a solid mixture; and a packaging step of packaging the solid mixture; It provides a method for producing a cosmetic composition in a freeze-dried formulation containing spicules, which includes a.

Hereinafter, a method for manufacturing a freeze-dried cosmetic composition containing spicules according to an embodiment of the present invention can be explained through Figure 1.

First, spicules are separated and purified.

The spicule is a fine structure that forms the skeleton of a sponge (Spongilla Lacustris) and is a natural composite material made of calcium and silicate in the form of fine needles taken from seaweed or coral. The fibrous skeleton of the spicule has an absorption ability due to capillary action, and has a needle-like structure that allows it to penetrate the dermal layer of the skin and deliver active ingredients. Due to the above characteristics, it is mainly used as a cosmetic composition because it can improve acne skin, relieve acne marks and shallow scars, and show effects such as fine wrinkles, large pores, surface pigmentation, blemishes and blemishes management, and exfoliation.

The separation and purification in the present invention may be to separate the spicules according to size and select a size suitable for the purpose, and the separation and purification method may be performed in various ways known in the art as long as the spicule needle structure is not destroyed. and purification methods can be used without limitation.

In one embodiment, the spicule purification process involves applying mineral oil to the spicules after purification, drying them with hot air at 230-250°C, applying a mixed oil of argan oil and ginkgo oil in a 1:1 weight ratio, and then natural It may additionally include a drying step.

The mineral oil refers to a liquid hydrocarbon mixture extracted by refining petroleum. Mineral oils of low purity are used for industrial purposes, and mineral oils refined to high purity are used as cosmetics and edible ingredients.

The argan oil is an oil extracted from the fruit seeds of the Argania tree and is used as a raw material for medicine and cosmetics, as well as a spice used in salad dressings, soups, dipping sauces, etc.

The ginkgo oil refers to oil obtained by adding ginkgo fruit to cooking oil, heating it, extracting the fat-soluble active ingredients of the ginkgo, and then removing the ginkgo fruit.

In the present invention, the process of applying and drying mineral oil and then applying and drying the mixed oil improves the durability of the spicules during the oil coating and drying process, prevents damage to the spicules during freeze-drying, and prevents damage to the spicules during freeze-drying. When used on the skin, it may improve the skin penetration of spicules.

Next, the purified spicules, sodium hyaluronate, and algin are mixed to prepare a liquid mixture.

Sodium Hyaluronate is a sodium salt form of Hyaluronic Acid and is a type of mucopolysaccharide. Hyaluronic acid is a mucous substance that exists in the human body's connective tissue, joints, and eyes, and has the characteristic of being able to absorb and retain a lot of water. However, because hyaluronic acid has a large molecule, it is not easily absorbed into the skin, so sodium hyaluronate is made by combining hyaluronic acid with sodium to reduce the size of the molecule and facilitate skin absorption. Sodium hyaluronate is mainly used as an ingredient in cosmetics for the purpose of hydrating and moisturizing the skin.

The algin is the sodium salt of alginate, a carbohydrate purified by extracting brown algae (Phaeophyceae) with a dilute alkaline solution, and is also called sodium alginate. Algin is a type of organic acid that has high viscosity and is mainly used as an adhesive or emulsifier material.

In one embodiment, the mixing ratio of the purified spicule, sodium hyaluronate, and algin may be 2 to 4: 5: 2 by weight, respectively. If it deviates from the above mixing ratio conditions, the effective ingredient delivery effect of the cosmetic composition manufactured including it may be reduced.

In one embodiment, the liquid mixture manufacturing process further includes adding 5 to 10 parts by weight of the fermentation mixture based on 100 parts by weight of the liquid mixture, and the fermentation mixture includes persimmon leaves, ginseng fruit, bokbunja seed oil, and cacao. Nibs, purified water, and Cheonggukguk culture broth may be ground and mixed at a weight ratio of 10:20:10:15:44:1 and then fermented for 30 to 50 hours.

The persimmon leaves refer to the leaves of the persimmon tree (Diospyros kaki), a deciduous broad-leaved tree of the dicotyledonous plant Persimmon family. Persimmon leaves are rich in vitamin C, which has the effect of strengthening immunity and suppressing viral infections. It contains catechin, which prevents cell damage that causes fatigue, and contains rutin, which has the effect of improving blood circulation.

The ginseng fruit refers to the fruit produced from 4-year-old ginseng among ginseng (Panax ginseng), a perennial herb belonging to the dicotyledonous Araliaceae family. Ginseng fruit is rich in saponin and is known to improve blood flow, enhance immunity, have antioxidant effects, and improve cholesterol levels, and is mainly used as a health functional food.

The bokbunja seed oil refers to oil extracted from the fruit of the bokbunja (Rubus coreanus), a deciduous shrub belonging to the Rosaceae family, by removing the pulp and pressing the remaining seeds. Bokbunja seed oil contains omega-3, omega-6, polyphenol, and gamma-linolenic acid, and is known to improve blood circulation and cholesterol levels, and is effective against osteoporosis and dementia.

The cacao nibs refer to the kernels obtained by drying, fermenting, and roasting cacao beans of the cacao tree (Theobroma cacao), a tree of the dicotyledonous plant mallow family, and removing the skin. Cacao nibs are less processed than chocolate and contain more of the original ingredients of cacao, making them popular as a health food. Cacao nibs contain polyphenols such as catechin and procyanidin, which are effective in preventing aging, relieving fatigue, and improving immunity. They are also rich in dietary fiber, which helps with diet.

The Cheongguk bacteria are also called Cheongguk enteric bacteria and refer to bacteria produced during the fermentation of Cheonggukjang. However, in modern times, excellent bacteria are selected and inoculated. It is a type of Bacillus subtilis and is known to grow best when using soybeans as a medium.

In the present invention, the Cheonggukgyun culture medium may be mixed with persimmon leaves, ginseng fruit, bokbunja seed oil, cacao nibs, and purified water to increase the active ingredient content of the fermentation mixture through a fermentation process.

The fermentation mixture in the present invention may be added to the liquid mixture to reduce inflammatory reactions in the skin and promote skin cell recovery when using a cosmetic composition containing it. The cosmetic composition to which the fermentation mixture according to an embodiment of the present invention is added suppresses the inflammatory response that may occur when spicules penetrate the skin and promotes the recovery of skin cells, thereby promoting the active ingredient of the cosmetic composition containing spicules. This may be to maintain the penetration effect and at the same time reduce the inflammatory response and stinging that may occur when using a cosmetic composition containing spicules.

Next, the liquid mixture is filled into a freeze-drying mold and then freeze-dried to prepare a solid mixture.

The freeze-drying mold is used as a mold to create a formulation of the desired shape and size during the process of freeze-drying the liquid mixture. Molds of various structures can be used as long as they do not deteriorate or reduce the efficacy of the cosmetic composition or damage the shape of the cosmetic composition. It can be used without restrictions.

The freeze-drying method can be used without limitation as long as it does not deteriorate or reduce the efficacy of the cosmetic composition or damage the shape of the cosmetic composition. However, the freeze-drying method in the present invention specifically involves the liquid phase. A freezing step of freezing the mixture at -1°C or lower; sequentially maintaining the frozen mixture at temperatures below -40°C and below -10°C for 2 to 6 hours at 100 to 1,000 ubar; Maintaining above -10°C and below -5°C for 2 to 6 hours; Maintaining above -5°C and below 0°C for 2 to 6 hours; Maintaining above 0°C and below 10°C for 30 minutes to 2 hours; Maintaining the temperature above 10°C and below 20°C for 30 minutes to 2 hours; Maintaining the temperature above 20°C and below 30°C for 30 minutes to 2 hours; Maintaining above 30°C and below 45°C for 30 minutes to 2 hours; and separating the lyophilized solid mixture from the mold; It may include.

In one embodiment, the freeze-drying step is performed by adding 10 parts by weight of a 70 to 90% by volume ethanol aqueous solution and 2 parts by weight of mineral oil to the liquid mixture relative to 100 parts by weight of the liquid mixture before filling the freeze-drying mold, and then drying the liquid mixture for 50 to 60 parts by weight. It may further include the step of heating to ℃ and then mixing to induce emulsion.

The ethanol refers to an alcohol in which one hydrogen atom of ethane, which has two carbon atoms among chain hydrocarbons, is replaced with a hydroxy group. It is the main ingredient in alcohol, a widely used disinfectant, and a major solvent in industrial chemistry. 70-90% by volume ethanol aqueous solution is ethanol diluted in water, meaning 70-90% by volume of ethanol mixed with 10-30% by volume of water. In the present invention, ethanol may be included in the liquid mixture to help dry the liquid mixture into a porous solid mixture during freeze-drying and at the same time prevent spicules from being damaged during the freeze-drying process. If the purity of ethanol is less than 70% or more than 90%, the above effect may be reduced.

The mineral oil refers to a liquid hydrocarbon mixture extracted by refining petroleum. Mineral oils of low purity are used for industrial purposes, and mineral oils refined to high purity are used as cosmetics and edible ingredients.

The emulsification is also called emulsification and means dispersing another liquid that does not mix with another liquid into fine particles or the dispersed state. One of the two liquids that do not dissolve in each other becomes fine particles and dissolves in the other liquid. This refers to the phenomenon of creating an emulsion by dispersing it in the body.

In the present invention, the process of adding ethanol and mineral oil to the liquid mixture before freeze-drying may help dry the liquid mixture into a porous solid mixture during freeze-drying and prevent spicules from being damaged during the freeze-drying process.

Finally, the solid mixture is packaged to complete a freeze-dried cosmetic composition containing spicules.

The packaging can use various conventionally known packaging methods without limitation as long as it does not deteriorate or reduce the efficacy of the cosmetic composition or damage the shape of the cosmetic composition.

Another aspect of the present application provides a cosmetic composition in a freeze-dried formulation containing spicules prepared by the above-described manufacturing method.

In the cosmetic composition, in addition to the above essential ingredients, other ingredients may be appropriately mixed within the range that does not impair the purpose of the present invention depending on the type of formulation or purpose of use, etc. in each formulation.

The cosmetic composition may contain a generally acceptable carrier, and may be appropriately mixed with, for example, oil, water, surfactant, moisturizer, lower alcohol, thickener, chelating agent, colorant, preservative, fragrance, etc., but is limited thereto. no.

The acceptable carrier may vary depending on the formulation. For example, when formulated into ointments, pastes, creams or gels, animal oil, vegetable oil, wax, paraffin, starch, tracant, cellulose derivatives, polyethylene glycol, silicone, bentonite, silica, talc, zinc oxide or these are used as carrier ingredients. Mixtures may be used.

The cosmetic composition may contain fatty substances, organic solvents, solubilizers, thickeners, gelling agents, softeners, antioxidants, suspending agents, stabilizers, foaming agents, and fragrances commonly used in the industry depending on the quality or function of the final product. , surfactants, water, ionic or non-ionic emulsifiers, fillers, sequestering agents, chelating agents, preservatives, blocking agents, wetting agents, essential oils, dyes, pigments, hydrophilic or lipophilic activators, commonly used in cosmetics. It may additionally contain auxiliaries commonly used in the fields of cosmetology or dermatology, such as any other ingredients.

However, the auxiliaries and their mixing ratio may be appropriately selected so as not to affect the desirable properties of the cosmetic composition according to the present invention.

Hereinafter, the configuration of the present invention and its effects will be described in more detail through specific examples and comparative examples. However, these examples are for illustrating the present invention in more detail, and the scope of the present invention is not limited to these examples.

[Example 1]

First, spicules were placed in a test tube containing a solution of water and agar powder mixed at a weight ratio of 9:1, centrifuged, and then discarded, leaving behind only the sediment that had settled on the lower layer of the test tube. Then, the sediment was dissolved in a water tank and filtered. The spicules obtained by filtering were naturally dried to obtain purified spicules.

Next, the purified spicule, sodium hyaluronate, and algin were mixed at a weight ratio of 4:5:2, respectively, to prepare a liquid mixture.

Next, the liquid mixture was filled into a freeze-drying mold and the liquid mixture was frozen at -1°C or lower. The frozen mixture was sequentially kept at -20°C for 4 hours under 600 ubar for primary drying, and then kept at -8°C for 4 hours for secondary drying. The second-dried mixture was kept at -3°C for 4 hours for third drying, and then kept at 5°C for 1 hour for fourth drying. The fourth-dried mixture was kept at 15°C for 1 hour to dry the fifth time, and then kept at 25°C for one hour to dry the sixth time. The sixth dried mixture was kept at 40°C for 30 minutes to complete final drying, and then the freeze-dried solid mixture was separated from the mold.

Finally, the solid mixture was packaged to complete a freeze-dried cosmetic composition containing spicules. The completed cosmetic composition was named Example 1.

[Example 2]

It was prepared in the same manner as Example 1, but during the freeze-drying process, before filling the freeze-drying mold, 10 parts by weight of a 70-90% by volume ethanol aqueous solution and 2 parts by weight of mineral oil were added to the liquid mixture for 100 parts by weight of the liquid mixture. The cosmetic composition prepared by additionally including the step of heating to 50-60°C and then mixing to induce emulsion was named Example 2.

[Example 3]

It was prepared in the same manner as Example 1, but in the process of preparing the liquid mixture, persimmon leaves, ginseng fruit, bokbunja seed oil, cacao nibs, purified water, and Cheonggukgung culture medium were ground and mixed at a weight ratio of 10: 20: 10: 15: 44: 1. The cosmetic composition prepared by further including the step of adding 6 parts by weight of the fermented mixture prepared by fermenting for 30 to 50 hours based on 100 parts by weight of the liquid mixture was named Example 3.

[Example 4]

It was prepared in the same manner as in Example 1, but during the spicule separation and purification process, mineral oil was applied to the spicules after purification, then dried with hot air at 230-250°C, and then argan oil and ginkgo oil were mixed in a 1:1 weight ratio. The cosmetic composition prepared by additionally including the step of applying oil and drying naturally was named Example 4.

[Comparative Example 1]

A cosmetic manufactured in the same manner as Example 1, but replacing the freeze-drying process by freezing the liquid mixture at -1°C or lower during the freeze-drying process and then maintaining the frozen mixture at -10°C for 24 hours under 1000 ubar. The composition was named Comparative Example 1.

[Experimental Example 1: Comparison of spicule damage rates]

An experiment was conducted to confirm whether spicules were intact in the freeze-dried cosmetic composition.

The cosmetic compositions of Examples 1 to 4 and Comparative Example 1 were placed in a petri dish, and 30 ml of distilled water was added to dissolve the solid cosmetic composition.

The dissolved cosmetic composition was measured through a microscope to count the number of spicules in an area of 5mm

Example 1 Example 2 Example 3 Example 4 Comparative Example 1 Damage rate (%) 9.1 4.4 9.3 5.6 22.3

As shown in Table 1, the spicule damage rate of the cosmetic compositions of Examples 1 to 4 was confirmed to be less than 10%, showing that the spicules were well preserved even after the cosmetic composition according to the manufacturing method of the present invention was freeze-dried. could be confirmed.

In particular, it was confirmed that the breakage rate of Examples 2 and 4 was lower than that of Example 1, and the process of adding ethanol and mineral oil to the liquid mixture before freeze-drying and emulsifying it, and the process of applying oil to spicules and drying them It was confirmed that the progress of the process affected the spicule damage rate.

On the other hand, it was confirmed that the damage rate of Comparative Example 1 was increased compared to Example 1, and it was determined that freeze-drying performed while sequentially changing the temperature lowered the damage rate.

Claims (3)

A spicule purification step of separating and purifying spicules;
A liquid mixture is prepared by mixing the purified spicule, sodium hyaluronate, and algin, and then 5 to 10 parts by weight of the fermentation mixture is added to 100 parts by weight of the liquid mixture, and the fermentation mixture includes persimmon leaves, ginseng fruits, Bokbunja seed oil, cacao nibs, purified water, and Cheonggukgye culture broth were crushed and mixed in a weight ratio of 10: 20: 10: 15: 44: 1, and then fermented for 30 to 50 hours. Liquid mixing step;
A freeze-drying step of filling the liquid mixture into a freeze-drying mold and then freeze-drying it to prepare a solid mixture; and
A packaging step of packaging the solid mixture; A method for producing a cosmetic composition in a freeze-dried formulation containing spicules, comprising:
According to paragraph 1,
In the freeze-drying step, before filling the mold for freeze-drying, 10 parts by weight of 70-90 volume% ethanol aqueous solution and 2 parts by weight of mineral oil are added to the liquid mixture, heated to 50-60 ° C., and then mixed. A method for producing a cosmetic composition in a freeze-dried formulation containing spicules, further comprising the step of inducing emulsion. delete