KR102659322B1 - 피부병 치료를 위한 융합된 헤테로방향족-아닐린 화합물 - Google Patents
피부병 치료를 위한 융합된 헤테로방향족-아닐린 화합물 Download PDFInfo
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- XOOUIPVCVHRTMJ-UHFFFAOYSA-L zinc stearate Chemical compound [Zn+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O XOOUIPVCVHRTMJ-UHFFFAOYSA-L 0.000 description 1
- 229940036139 zyrtec Drugs 0.000 description 1
- 125000004933 β-carbolinyl group Chemical group C1(=NC=CC=2C3=CC=CC=C3NC12)* 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4355—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762508997P | 2017-05-19 | 2017-05-19 | |
| US62/508,997 | 2017-05-19 | ||
| PCT/US2018/033544 WO2018213807A1 (en) | 2017-05-19 | 2018-05-18 | Fused heteroaromatic-aniline compounds for treatment of dermal disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20200026812A KR20200026812A (ko) | 2020-03-11 |
| KR102659322B1 true KR102659322B1 (ko) | 2024-04-22 |
Family
ID=62620965
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020197037274A Active KR102659322B1 (ko) | 2017-05-19 | 2018-05-18 | 피부병 치료를 위한 융합된 헤테로방향족-아닐린 화합물 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US10988483B2 (https=) |
| EP (1) | EP3624795B1 (https=) |
| JP (1) | JP7237941B2 (https=) |
| KR (1) | KR102659322B1 (https=) |
| CN (1) | CN111093658B (https=) |
| AU (1) | AU2018270292B2 (https=) |
| CA (1) | CA3063535A1 (https=) |
| DK (1) | DK3624795T3 (https=) |
| ES (1) | ES2913213T3 (https=) |
| IL (1) | IL270576B (https=) |
| MA (1) | MA49140A (https=) |
| MX (1) | MX2019013562A (https=) |
| WO (1) | WO2018213807A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7237941B2 (ja) * | 2017-05-19 | 2023-03-13 | エヌフレクション セラピューティクス インコーポレイテッド | 皮膚障害の処置用の融合複素環式芳香族アニリン化合物 |
| CA3120351A1 (en) * | 2018-11-20 | 2020-05-28 | Nflection Therapeutics, Inc. | Aryl-aniline and heteroaryl-aniline compounds for treatment of skin cancers |
| WO2020106308A1 (en) | 2018-11-20 | 2020-05-28 | Nflection Therapeutics, Inc. | Naphthyridinone-aniline compounds for treatment of dermal disorders |
| WO2020106306A1 (en) | 2018-11-20 | 2020-05-28 | Nflection Therapeutics, Inc. | Cyanoaryl-aniline compounds for treatment of dermal disorders |
| WO2020106305A1 (en) | 2018-11-20 | 2020-05-28 | Nflection Therapeutics, Inc. | Thienyl-aniline compounds for treatment of dermal disorders |
| EP4233834A3 (en) * | 2018-11-20 | 2023-10-25 | NFlection Therapeutics, Inc. | Aryl-aniline and heteroaryl-aniline compounds for treatment of birthmarks |
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| US4008719A (en) | 1976-02-02 | 1977-02-22 | Alza Corporation | Osmotic system having laminar arrangement for programming delivery of active agent |
| HU196714B (en) | 1984-10-04 | 1989-01-30 | Monsanto Co | Process for producing non-aqueous composition comprising somatotropin |
| IE58110B1 (en) | 1984-10-30 | 1993-07-14 | Elan Corp Plc | Controlled release powder and process for its preparation |
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| IT1229203B (it) | 1989-03-22 | 1991-07-25 | Bioresearch Spa | Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative. |
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| US5733566A (en) | 1990-05-15 | 1998-03-31 | Alkermes Controlled Therapeutics Inc. Ii | Controlled release of antiparasitic agents in animals |
| US5580578A (en) | 1992-01-27 | 1996-12-03 | Euro-Celtique, S.A. | Controlled release formulations coated with aqueous dispersions of acrylic polymers |
| TW333456B (en) | 1992-12-07 | 1998-06-11 | Takeda Pharm Ind Co Ltd | A pharmaceutical composition of sustained-release preparation the invention relates to a pharmaceutical composition of sustained-release preparation which comprises a physiologically active peptide. |
| US5591767A (en) | 1993-01-25 | 1997-01-07 | Pharmetrix Corporation | Liquid reservoir transdermal patch for the administration of ketorolac |
| US6087324A (en) | 1993-06-24 | 2000-07-11 | Takeda Chemical Industries, Ltd. | Sustained-release preparation |
| IT1270594B (it) | 1994-07-07 | 1997-05-07 | Recordati Chem Pharm | Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida |
| AU6242096A (en) | 1995-06-27 | 1997-01-30 | Takeda Chemical Industries Ltd. | Method of producing sustained-release preparation |
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| JP2909418B2 (ja) | 1995-09-18 | 1999-06-23 | 株式会社資生堂 | 薬物の遅延放出型マイクロスフイア |
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| PT3624796T (pt) | 2017-05-19 | 2025-06-02 | Nflection Therapeutics Inc | Compostos de pirrolopiridina-anilina para tratamento de distúrbios dérmicos |
| JP7237941B2 (ja) | 2017-05-19 | 2023-03-13 | エヌフレクション セラピューティクス インコーポレイテッド | 皮膚障害の処置用の融合複素環式芳香族アニリン化合物 |
-
2018
- 2018-05-18 JP JP2020514155A patent/JP7237941B2/ja active Active
- 2018-05-18 EP EP18731592.4A patent/EP3624795B1/en active Active
- 2018-05-18 MX MX2019013562A patent/MX2019013562A/es unknown
- 2018-05-18 ES ES18731592T patent/ES2913213T3/es active Active
- 2018-05-18 CN CN201880048242.4A patent/CN111093658B/zh active Active
- 2018-05-18 CA CA3063535A patent/CA3063535A1/en active Pending
- 2018-05-18 WO PCT/US2018/033544 patent/WO2018213807A1/en not_active Ceased
- 2018-05-18 US US16/615,059 patent/US10988483B2/en active Active
- 2018-05-18 KR KR1020197037274A patent/KR102659322B1/ko active Active
- 2018-05-18 MA MA049140A patent/MA49140A/fr unknown
- 2018-05-18 AU AU2018270292A patent/AU2018270292B2/en active Active
- 2018-05-18 DK DK18731592.4T patent/DK3624795T3/da active
-
2019
- 2019-11-11 IL IL270576A patent/IL270576B/en unknown
-
2021
- 2021-04-20 US US17/235,018 patent/US11542271B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US11542271B2 (en) | 2023-01-03 |
| CA3063535A1 (en) | 2018-11-22 |
| US20210380601A1 (en) | 2021-12-09 |
| CN111093658B (zh) | 2022-10-14 |
| US10988483B2 (en) | 2021-04-27 |
| CN111093658A (zh) | 2020-05-01 |
| US20200172550A1 (en) | 2020-06-04 |
| MA49140A (fr) | 2020-03-25 |
| EP3624795B1 (en) | 2022-04-20 |
| IL270576B (en) | 2022-01-01 |
| EP3624795A1 (en) | 2020-03-25 |
| JP7237941B2 (ja) | 2023-03-13 |
| WO2018213807A1 (en) | 2018-11-22 |
| JP2020520994A (ja) | 2020-07-16 |
| KR20200026812A (ko) | 2020-03-11 |
| MX2019013562A (es) | 2020-08-03 |
| DK3624795T3 (da) | 2022-05-23 |
| ES2913213T3 (es) | 2022-06-01 |
| AU2018270292A1 (en) | 2019-12-05 |
| AU2018270292B2 (en) | 2022-02-10 |
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