KR102599298B1 - 전기천공을 사용하여 지방 조직의 생체내 형질감염을 최소로 침습성으로 하기 위한 방법 및 장치 - Google Patents

전기천공을 사용하여 지방 조직의 생체내 형질감염을 최소로 침습성으로 하기 위한 방법 및 장치 Download PDF

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KR102599298B1
KR102599298B1 KR1020227024752A KR20227024752A KR102599298B1 KR 102599298 B1 KR102599298 B1 KR 102599298B1 KR 1020227024752 A KR1020227024752 A KR 1020227024752A KR 20227024752 A KR20227024752 A KR 20227024752A KR 102599298 B1 KR102599298 B1 KR 102599298B1
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tissue
electrode
contact surface
electroporation device
electroporation
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Korean (ko)
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KR20220104077A (ko
Inventor
폴 피셔
케이트 브로데릭
제이 맥코이
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이노비오 파마수티컬즈, 인크.
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Priority to KR1020237037846A priority Critical patent/KR20230155616A/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/327—Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
    • A61N1/0416—Anode and cathode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
    • A61N1/0416—Anode and cathode
    • A61N1/042—Material of the electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
    • A61N1/0416—Anode and cathode
    • A61N1/0424—Shape of the electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Surgical Instruments (AREA)
  • Electrotherapy Devices (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Prostheses (AREA)
KR1020227024752A 2016-09-23 2017-09-22 전기천공을 사용하여 지방 조직의 생체내 형질감염을 최소로 침습성으로 하기 위한 방법 및 장치 Active KR102599298B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020237037846A KR20230155616A (ko) 2016-09-23 2017-09-22 전기천공을 사용하여 지방 조직의 생체내 형질감염을 최소로 침습성으로 하기 위한 방법 및 장치

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201662398932P 2016-09-23 2016-09-23
US62/398,932 2016-09-23
US201762480180P 2017-03-31 2017-03-31
US62/480,180 2017-03-31
KR1020217032742A KR102423446B1 (ko) 2016-09-23 2017-09-22 전기천공을 사용하여 지방 조직의 생체내 형질감염을 최소로 침습성으로 하기 위한 방법 및 장치
PCT/US2017/052970 WO2018057900A1 (en) 2016-09-23 2017-09-22 Method and device for minimally invasive in vivo transfection of adipose tissue using electroporation

Related Parent Applications (1)

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KR1020217032742A Division KR102423446B1 (ko) 2016-09-23 2017-09-22 전기천공을 사용하여 지방 조직의 생체내 형질감염을 최소로 침습성으로 하기 위한 방법 및 장치

Related Child Applications (1)

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KR1020237037846A Division KR20230155616A (ko) 2016-09-23 2017-09-22 전기천공을 사용하여 지방 조직의 생체내 형질감염을 최소로 침습성으로 하기 위한 방법 및 장치

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KR20220104077A KR20220104077A (ko) 2022-07-25
KR102599298B1 true KR102599298B1 (ko) 2023-11-07

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KR1020197010846A Active KR102313881B1 (ko) 2016-09-23 2017-09-22 전기천공을 사용하여 지방 조직의 생체내 형질감염을 최소로 침습성으로 하기 위한 방법 및 장치
KR1020237037846A Pending KR20230155616A (ko) 2016-09-23 2017-09-22 전기천공을 사용하여 지방 조직의 생체내 형질감염을 최소로 침습성으로 하기 위한 방법 및 장치
KR1020217032742A Active KR102423446B1 (ko) 2016-09-23 2017-09-22 전기천공을 사용하여 지방 조직의 생체내 형질감염을 최소로 침습성으로 하기 위한 방법 및 장치
KR1020227024752A Active KR102599298B1 (ko) 2016-09-23 2017-09-22 전기천공을 사용하여 지방 조직의 생체내 형질감염을 최소로 침습성으로 하기 위한 방법 및 장치

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KR1020197010846A Active KR102313881B1 (ko) 2016-09-23 2017-09-22 전기천공을 사용하여 지방 조직의 생체내 형질감염을 최소로 침습성으로 하기 위한 방법 및 장치
KR1020237037846A Pending KR20230155616A (ko) 2016-09-23 2017-09-22 전기천공을 사용하여 지방 조직의 생체내 형질감염을 최소로 침습성으로 하기 위한 방법 및 장치
KR1020217032742A Active KR102423446B1 (ko) 2016-09-23 2017-09-22 전기천공을 사용하여 지방 조직의 생체내 형질감염을 최소로 침습성으로 하기 위한 방법 및 장치

Country Status (10)

Country Link
US (2) US11684777B2 (enExample)
EP (2) EP4238607A3 (enExample)
JP (3) JP7181186B2 (enExample)
KR (4) KR102313881B1 (enExample)
CN (2) CN117482374A (enExample)
AU (4) AU2017331263B2 (enExample)
CA (2) CA3204936A1 (enExample)
ES (1) ES2970888T3 (enExample)
MX (2) MX2019003335A (enExample)
WO (1) WO2018057900A1 (enExample)

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CN110741076A (zh) * 2017-04-26 2020-01-31 拉瓦塔解决方案股份有限公司 用于电穿孔的微电极技术
WO2022115609A1 (en) * 2020-11-25 2022-06-02 Flagship Pioneering, Inc. Adipogenic cell compositions and methods

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US20030149451A1 (en) 2001-08-17 2003-08-07 Chomenky Victor I. Apparatus and method for reducing subcutaneous fat deposits by electroporation with improved comfort of patients
US20050182462A1 (en) 2000-08-17 2005-08-18 Chornenky Victor I. Apparatus and method for reducing subcutaneous fat deposits, virtual face lift and body sculpturing by electroporation
US20140277219A1 (en) 2013-03-14 2014-09-18 Zeltiq Aesthetics, Inc. Multi-modality treatment systems, methods and apparatus for altering subcutaneous lipid-rich tissue

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US20030149451A1 (en) 2001-08-17 2003-08-07 Chomenky Victor I. Apparatus and method for reducing subcutaneous fat deposits by electroporation with improved comfort of patients
US20140277219A1 (en) 2013-03-14 2014-09-18 Zeltiq Aesthetics, Inc. Multi-modality treatment systems, methods and apparatus for altering subcutaneous lipid-rich tissue

Also Published As

Publication number Publication date
KR20230155616A (ko) 2023-11-10
CA3037527A1 (en) 2018-03-29
AU2020250317A1 (en) 2020-11-12
JP2022188120A (ja) 2022-12-20
ES2970888T3 (es) 2024-05-31
US20200016400A1 (en) 2020-01-16
KR20220104077A (ko) 2022-07-25
EP4238607A3 (en) 2023-11-08
AU2017331263A1 (en) 2019-04-18
KR102313881B1 (ko) 2021-10-18
BR112019005740A2 (pt) 2019-06-18
EP4238607A2 (en) 2023-09-06
KR102423446B1 (ko) 2022-07-21
CN110022931B (zh) 2023-11-14
EP3515549B1 (en) 2023-11-22
AU2020250317B2 (en) 2023-01-05
US11684777B2 (en) 2023-06-27
AU2023202108A1 (en) 2023-05-04
KR20190055155A (ko) 2019-05-22
JP7448603B2 (ja) 2024-03-12
AU2025213675A1 (en) 2025-08-28
KR20210127797A (ko) 2021-10-22
CA3204936A1 (en) 2018-03-29
AU2017331263B2 (en) 2020-07-09
CN110022931A (zh) 2019-07-16
CN117482374A (zh) 2024-02-02
JP2024054418A (ja) 2024-04-16
JP2020500039A (ja) 2020-01-09
EP3515549A4 (en) 2020-06-10
MX2024007241A (es) 2024-06-26
JP7181186B2 (ja) 2022-11-30
US20230248965A1 (en) 2023-08-10
MX2019003335A (es) 2019-12-11
WO2018057900A1 (en) 2018-03-29
EP3515549A1 (en) 2019-07-31

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