KR102583062B1 - 동종중합체 인코딩된 핵산 메모리 - Google Patents

동종중합체 인코딩된 핵산 메모리 Download PDF

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KR102583062B1
KR102583062B1 KR1020197038747A KR20197038747A KR102583062B1 KR 102583062 B1 KR102583062 B1 KR 102583062B1 KR 1020197038747 A KR1020197038747 A KR 1020197038747A KR 20197038747 A KR20197038747 A KR 20197038747A KR 102583062 B1 KR102583062 B1 KR 102583062B1
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nucleic acid
homopolymer
strand
data
tracks
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KR20200027927A (ko
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윌리엄 제이. 에프카비치
매튜 티. 홀덴
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몰레큘러 어셈블리즈, 인크.
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    • G06—COMPUTING OR CALCULATING; COUNTING
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    • G06N3/12—Computing arrangements based on biological models using genetic models
    • G06N3/123—DNA computing
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    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
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    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
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    • G11B7/00—Recording or reproducing by optical means, e.g. recording using a thermal beam of optical radiation by modifying optical properties or the physical structure, reproducing using an optical beam at lower power by sensing optical properties; Record carriers therefor
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    • G—PHYSICS
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    • G11C11/00—Digital stores characterised by the use of particular electric or magnetic storage elements; Storage elements therefor
    • G11C11/54—Digital stores characterised by the use of particular electric or magnetic storage elements; Storage elements therefor using elements simulating biological cells, e.g. neuron
    • G—PHYSICS
    • G11—INFORMATION STORAGE
    • G11C—STATIC STORES
    • G11C13/00—Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00
    • G11C13/0002—Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00 using resistive RAM [RRAM] elements
    • G11C13/0009—RRAM elements whose operation depends upon chemical change
    • G11C13/0014—RRAM elements whose operation depends upon chemical change comprising cells based on organic memory material
    • G11C13/0019—RRAM elements whose operation depends upon chemical change comprising cells based on organic memory material comprising bio-molecules
    • G—PHYSICS
    • G11—INFORMATION STORAGE
    • G11C—STATIC STORES
    • G11C13/00—Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00
    • G11C13/02—Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00 using elements whose operation depends upon chemical change
    • G—PHYSICS
    • G11—INFORMATION STORAGE
    • G11C—STATIC STORES
    • G11C13/00—Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00
    • G11C13/04—Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00 using optical elements ; using other beam accessed elements, e.g. electron or ion beam
    • G11C13/048—Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00 using optical elements ; using other beam accessed elements, e.g. electron or ion beam using other optical storage elements
    • G—PHYSICS
    • G11—INFORMATION STORAGE
    • G11C—STATIC STORES
    • G11C7/00—Arrangements for writing information into, or reading information out from, a digital store
    • G—PHYSICS
    • G11—INFORMATION STORAGE
    • G11C—STATIC STORES
    • G11C7/00—Arrangements for writing information into, or reading information out from, a digital store
    • G11C7/10—Input/output [I/O] data interface arrangements, e.g. I/O data control circuits, I/O data buffers
    • G11C7/1006—Data managing, e.g. manipulating data before writing or reading out, data bus switches or control circuits therefor
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/10—Sequence alignment; Homology search
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
    • G16B50/30—Data warehousing; Computing architectures

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  • Physics & Mathematics (AREA)
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  • Chemical & Material Sciences (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
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  • Spectroscopy & Molecular Physics (AREA)
  • Analytical Chemistry (AREA)
  • Medical Informatics (AREA)
  • Biomedical Technology (AREA)
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  • Computational Linguistics (AREA)
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  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioethics (AREA)
  • Databases & Information Systems (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Computer Hardware Design (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
KR1020197038747A 2017-05-31 2018-05-31 동종중합체 인코딩된 핵산 메모리 Active KR102583062B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762513111P 2017-05-31 2017-05-31
US62/513,111 2017-05-31
PCT/US2018/035365 WO2018222853A1 (en) 2017-05-31 2018-05-31 Homopolymer encoded nucleic acid memory

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KR20200027927A KR20200027927A (ko) 2020-03-13
KR102583062B1 true KR102583062B1 (ko) 2023-09-25

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US (1) US10982276B2 (https=)
EP (1) EP3630350A4 (https=)
JP (1) JP7277054B2 (https=)
KR (1) KR102583062B1 (https=)
WO (1) WO2018222853A1 (https=)

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US10774366B2 (en) 2016-03-11 2020-09-15 President And Fellows Of Harvard College Method of making polynucleotides using closed-loop verification
WO2017176541A1 (en) 2016-04-04 2017-10-12 President And Fellows Of Harvard College Enzymatic nucleic acid synthesis
US10745814B2 (en) 2016-05-09 2020-08-18 President And Fellows Of Harvard College Enzymatic nucleic acid synthesis
AU2017363139B2 (en) 2016-11-16 2023-09-21 Catalog Technologies, Inc. Nucleic acid-based data storage
US11174512B2 (en) 2017-05-31 2021-11-16 Molecular Assemblies, Inc. Homopolymer encoded nucleic acid memory
US11612873B2 (en) * 2017-05-31 2023-03-28 Molecular Assemblies, Inc. Homopolymer encoded nucleic acid memory
GB201801768D0 (en) 2018-02-02 2018-03-21 Oxford Nanopore Tech Ltd Synthesis method
WO2019178551A1 (en) 2018-03-16 2019-09-19 Catalog Technologies, Inc. Chemical methods for nucleic acid-based data storage
US11339423B2 (en) * 2018-03-18 2022-05-24 Bryan Bishop Systems and methods for data storage in nucleic acids
AU2019311199B2 (en) 2018-07-23 2024-12-19 Dna Script Massively parallel enzymatic synthesis of nucleic acid strands
US12437841B2 (en) 2018-08-03 2025-10-07 Catalog Technologies, Inc. Systems and methods for storing and reading nucleic acid-based data with error protection
SG11202105441WA (en) 2018-12-13 2021-06-29 Dna Script Direct oligonucleotide synthesis on cells and biomolecules
GB201821155D0 (en) * 2018-12-21 2019-02-06 Oxford Nanopore Tech Ltd Method
EP3959330A4 (en) * 2019-04-24 2023-07-05 Molecular Assemblies, Inc. HOMOPOLYMER ENCODED NUCLEIC ACID MEMORY
US11610651B2 (en) 2019-05-09 2023-03-21 Catalog Technologies, Inc. Data structures and operations for searching, computing, and indexing in DNA-based data storage
WO2020243075A1 (en) 2019-05-31 2020-12-03 Illumina, Inc. Storage device, system, and method
CN115151652B (zh) * 2020-02-25 2025-02-07 Dna斯克瑞普特公司 用于酶促合成多核苷酸的方法和设备
CN111489791B (zh) * 2020-04-07 2023-05-26 中国科学院重庆绿色智能技术研究院 固态纳米孔高密度编码dna数字存储读取方法
JP2023546315A (ja) * 2020-09-08 2023-11-02 カタログ テクノロジーズ， インコーポレイテッド 核酸の配列決定による書き込みのためのシステムおよび方法
EP4377476A4 (en) * 2021-07-28 2025-06-18 NAIO, Inc. Compositions, systems, and methods for nucleic acid data storage
US12014256B2 (en) 2022-01-12 2024-06-18 Dell Products L.P Polysaccharide archival storage

Citations (1)

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US20170017436A1 (en) * 2015-07-13 2017-01-19 President And Fellows Of Harvard College Methods for Retrievable Information Storage Using Nucleic Acids

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EP2952590B1 (en) * 2010-06-11 2017-07-26 Life Technologies Corporation Alternative nucleotide flows in sequencing-by-synthesis methods
WO2012088339A2 (en) 2010-12-22 2012-06-28 Genia Technologies, Inc. Nanopore-based single dna molecule characterization using speed bumps
JP6333179B2 (ja) * 2012-01-20 2018-05-30 ジニア テクノロジーズ， インコーポレイテッド ナノポアベースの分子検出および配列決定
CN108875312A (zh) * 2012-07-19 2018-11-23 哈佛大学校长及研究员协会 利用核酸存储信息的方法
US10683536B2 (en) 2013-04-02 2020-06-16 Molecular Assemblies, Inc. Reusable initiators for synthesizing nucleic acids
CN105264085B (zh) * 2013-10-15 2020-10-13 分子组装有限责任公司 合成核酸的方法和设备
JP7023842B2 (ja) * 2015-10-29 2022-02-22 テンプル ユニヴァーシティ － オブ ザ コモンウェルス システム オブ ハイアー エデュケーション Ｄｎａポリメラーゼシータによる核酸の３’末端の修飾
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JP7277054B2 (ja) 2023-05-18
EP3630350A1 (en) 2020-04-08
EP3630350A4 (en) 2021-03-31
KR20200027927A (ko) 2020-03-13
US10982276B2 (en) 2021-04-20
WO2018222853A1 (en) 2018-12-06
JP2020522257A (ja) 2020-07-30
US20190040459A1 (en) 2019-02-07

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