JP7277054B2 - ホモポリマーコード化核酸メモリ - Google Patents

ホモポリマーコード化核酸メモリ Download PDF

Info

Publication number
JP7277054B2
JP7277054B2 JP2019566571A JP2019566571A JP7277054B2 JP 7277054 B2 JP7277054 B2 JP 7277054B2 JP 2019566571 A JP2019566571 A JP 2019566571A JP 2019566571 A JP2019566571 A JP 2019566571A JP 7277054 B2 JP7277054 B2 JP 7277054B2
Authority
JP
Japan
Prior art keywords
nucleic acid
tracts
data
strand
acid memory
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2019566571A
Other languages
English (en)
Japanese (ja)
Other versions
JPWO2018222853A5 (https=
JP2020522257A (ja
JP2020522257A5 (https=
Inventor
ジェイ. ウィリアム エフカビッチ,
マシュー ティー. ホールデン,
Original Assignee
モレキュラー アッセンブリーズ, インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by モレキュラー アッセンブリーズ, インコーポレイテッド filed Critical モレキュラー アッセンブリーズ, インコーポレイテッド
Publication of JP2020522257A publication Critical patent/JP2020522257A/ja
Publication of JPWO2018222853A5 publication Critical patent/JPWO2018222853A5/ja
Publication of JP2020522257A5 publication Critical patent/JP2020522257A5/ja
Application granted granted Critical
Publication of JP7277054B2 publication Critical patent/JP7277054B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B50/00ICT programming tools or database systems specially adapted for bioinformatics
    • G16B50/20Heterogeneous data integration
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N3/00Computing arrangements based on biological models
    • G06N3/12Computing arrangements based on biological models using genetic models
    • G06N3/123DNA computing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • GPHYSICS
    • G11INFORMATION STORAGE
    • G11BINFORMATION STORAGE BASED ON RELATIVE MOVEMENT BETWEEN RECORD CARRIER AND TRANSDUCER
    • G11B7/00Recording or reproducing by optical means, e.g. recording using a thermal beam of optical radiation by modifying optical properties or the physical structure, reproducing using an optical beam at lower power by sensing optical properties; Record carriers therefor
    • G11B7/24Record carriers characterised by shape, structure or physical properties, or by the selection of the material
    • G11B7/241Record carriers characterised by shape, structure or physical properties, or by the selection of the material characterised by the selection of the material
    • G11B7/242Record carriers characterised by shape, structure or physical properties, or by the selection of the material characterised by the selection of the material of recording layers
    • G11B7/244Record carriers characterised by shape, structure or physical properties, or by the selection of the material characterised by the selection of the material of recording layers comprising organic materials only
    • G11B7/245Record carriers characterised by shape, structure or physical properties, or by the selection of the material characterised by the selection of the material of recording layers comprising organic materials only containing a polymeric component
    • GPHYSICS
    • G11INFORMATION STORAGE
    • G11CSTATIC STORES
    • G11C11/00Digital stores characterised by the use of particular electric or magnetic storage elements; Storage elements therefor
    • G11C11/54Digital stores characterised by the use of particular electric or magnetic storage elements; Storage elements therefor using elements simulating biological cells, e.g. neuron
    • GPHYSICS
    • G11INFORMATION STORAGE
    • G11CSTATIC STORES
    • G11C13/00Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00
    • G11C13/0002Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00 using resistive RAM [RRAM] elements
    • G11C13/0009RRAM elements whose operation depends upon chemical change
    • G11C13/0014RRAM elements whose operation depends upon chemical change comprising cells based on organic memory material
    • G11C13/0019RRAM elements whose operation depends upon chemical change comprising cells based on organic memory material comprising bio-molecules
    • GPHYSICS
    • G11INFORMATION STORAGE
    • G11CSTATIC STORES
    • G11C13/00Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00
    • G11C13/02Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00 using elements whose operation depends upon chemical change
    • GPHYSICS
    • G11INFORMATION STORAGE
    • G11CSTATIC STORES
    • G11C13/00Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00
    • G11C13/04Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00 using optical elements ; using other beam accessed elements, e.g. electron or ion beam
    • G11C13/048Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00 using optical elements ; using other beam accessed elements, e.g. electron or ion beam using other optical storage elements
    • GPHYSICS
    • G11INFORMATION STORAGE
    • G11CSTATIC STORES
    • G11C7/00Arrangements for writing information into, or reading information out from, a digital store
    • GPHYSICS
    • G11INFORMATION STORAGE
    • G11CSTATIC STORES
    • G11C7/00Arrangements for writing information into, or reading information out from, a digital store
    • G11C7/10Input/output [I/O] data interface arrangements, e.g. I/O data control circuits, I/O data buffers
    • G11C7/1006Data managing, e.g. manipulating data before writing or reading out, data bus switches or control circuits therefor
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/10Sequence alignment; Homology search
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B50/00ICT programming tools or database systems specially adapted for bioinformatics
    • G16B50/30Data warehousing; Computing architectures

Landscapes

  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Theoretical Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Evolutionary Biology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Analytical Chemistry (AREA)
  • Medical Informatics (AREA)
  • Biomedical Technology (AREA)
  • Evolutionary Computation (AREA)
  • Artificial Intelligence (AREA)
  • Mathematical Physics (AREA)
  • Software Systems (AREA)
  • Computing Systems (AREA)
  • Data Mining & Analysis (AREA)
  • Computational Linguistics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioethics (AREA)
  • Databases & Information Systems (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Computer Hardware Design (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2019566571A 2017-05-31 2018-05-31 ホモポリマーコード化核酸メモリ Active JP7277054B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762513111P 2017-05-31 2017-05-31
US62/513,111 2017-05-31
PCT/US2018/035365 WO2018222853A1 (en) 2017-05-31 2018-05-31 Homopolymer encoded nucleic acid memory

Publications (4)

Publication Number Publication Date
JP2020522257A JP2020522257A (ja) 2020-07-30
JPWO2018222853A5 JPWO2018222853A5 (https=) 2023-04-03
JP2020522257A5 JP2020522257A5 (https=) 2023-04-03
JP7277054B2 true JP7277054B2 (ja) 2023-05-18

Family

ID=64455058

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019566571A Active JP7277054B2 (ja) 2017-05-31 2018-05-31 ホモポリマーコード化核酸メモリ

Country Status (5)

Country Link
US (1) US10982276B2 (https=)
EP (1) EP3630350A4 (https=)
JP (1) JP7277054B2 (https=)
KR (1) KR102583062B1 (https=)
WO (1) WO2018222853A1 (https=)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10774366B2 (en) 2016-03-11 2020-09-15 President And Fellows Of Harvard College Method of making polynucleotides using closed-loop verification
WO2017176541A1 (en) 2016-04-04 2017-10-12 President And Fellows Of Harvard College Enzymatic nucleic acid synthesis
US10745814B2 (en) 2016-05-09 2020-08-18 President And Fellows Of Harvard College Enzymatic nucleic acid synthesis
AU2017363139B2 (en) 2016-11-16 2023-09-21 Catalog Technologies, Inc. Nucleic acid-based data storage
US11174512B2 (en) 2017-05-31 2021-11-16 Molecular Assemblies, Inc. Homopolymer encoded nucleic acid memory
US11612873B2 (en) * 2017-05-31 2023-03-28 Molecular Assemblies, Inc. Homopolymer encoded nucleic acid memory
GB201801768D0 (en) 2018-02-02 2018-03-21 Oxford Nanopore Tech Ltd Synthesis method
WO2019178551A1 (en) 2018-03-16 2019-09-19 Catalog Technologies, Inc. Chemical methods for nucleic acid-based data storage
US11339423B2 (en) * 2018-03-18 2022-05-24 Bryan Bishop Systems and methods for data storage in nucleic acids
AU2019311199B2 (en) 2018-07-23 2024-12-19 Dna Script Massively parallel enzymatic synthesis of nucleic acid strands
US12437841B2 (en) 2018-08-03 2025-10-07 Catalog Technologies, Inc. Systems and methods for storing and reading nucleic acid-based data with error protection
SG11202105441WA (en) 2018-12-13 2021-06-29 Dna Script Direct oligonucleotide synthesis on cells and biomolecules
GB201821155D0 (en) * 2018-12-21 2019-02-06 Oxford Nanopore Tech Ltd Method
EP3959330A4 (en) * 2019-04-24 2023-07-05 Molecular Assemblies, Inc. HOMOPOLYMER ENCODED NUCLEIC ACID MEMORY
US11610651B2 (en) 2019-05-09 2023-03-21 Catalog Technologies, Inc. Data structures and operations for searching, computing, and indexing in DNA-based data storage
WO2020243075A1 (en) 2019-05-31 2020-12-03 Illumina, Inc. Storage device, system, and method
CN115151652B (zh) * 2020-02-25 2025-02-07 Dna斯克瑞普特公司 用于酶促合成多核苷酸的方法和设备
CN111489791B (zh) * 2020-04-07 2023-05-26 中国科学院重庆绿色智能技术研究院 固态纳米孔高密度编码dna数字存储读取方法
JP2023546315A (ja) * 2020-09-08 2023-11-02 カタログ テクノロジーズ, インコーポレイテッド 核酸の配列決定による書き込みのためのシステムおよび方法
EP4377476A4 (en) * 2021-07-28 2025-06-18 NAIO, Inc. Compositions, systems, and methods for nucleic acid data storage
US12014256B2 (en) 2022-01-12 2024-06-18 Dell Products L.P Polysaccharide archival storage

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015505458A (ja) 2012-01-20 2015-02-23 ジニア テクノロジーズ, インコーポレイテッド ナノポアベースの分子検出および配列決定
JP2015533077A (ja) 2012-07-19 2015-11-19 プレジデント アンド フェローズ オブ ハーバード カレッジ 核酸を用いた情報記憶方法
JP2016515391A (ja) 2013-10-15 2016-05-30 モレキュラー アセンブリー, エルエルシー 核酸を合成するための方法および装置
WO2017011492A1 (en) 2015-07-13 2017-01-19 President And Fellows Of Harvard College Methods for retrievable information storage using nucleic acids
WO2017075421A1 (en) 2015-10-29 2017-05-04 Temple University-Of The Commonwealth System Of Higher Education Modification of 3' terminal ends of nucleic acids by dna polymerase theta

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2952590B1 (en) * 2010-06-11 2017-07-26 Life Technologies Corporation Alternative nucleotide flows in sequencing-by-synthesis methods
WO2012088339A2 (en) 2010-12-22 2012-06-28 Genia Technologies, Inc. Nanopore-based single dna molecule characterization using speed bumps
US10683536B2 (en) 2013-04-02 2020-06-16 Molecular Assemblies, Inc. Reusable initiators for synthesizing nucleic acids
RU2022101599A (ru) 2016-02-29 2022-02-25 Айридия, Инк. Способы, композиции и устройства для хранения информации
AU2017363139B2 (en) 2016-11-16 2023-09-21 Catalog Technologies, Inc. Nucleic acid-based data storage
CN110431148A (zh) 2017-01-10 2019-11-08 罗斯威尔生命技术公司 用于dna数据存储的方法和系统

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015505458A (ja) 2012-01-20 2015-02-23 ジニア テクノロジーズ, インコーポレイテッド ナノポアベースの分子検出および配列決定
JP2015533077A (ja) 2012-07-19 2015-11-19 プレジデント アンド フェローズ オブ ハーバード カレッジ 核酸を用いた情報記憶方法
JP2016515391A (ja) 2013-10-15 2016-05-30 モレキュラー アセンブリー, エルエルシー 核酸を合成するための方法および装置
WO2017011492A1 (en) 2015-07-13 2017-01-19 President And Fellows Of Harvard College Methods for retrievable information storage using nucleic acids
WO2017075421A1 (en) 2015-10-29 2017-05-04 Temple University-Of The Commonwealth System Of Higher Education Modification of 3' terminal ends of nucleic acids by dna polymerase theta

Also Published As

Publication number Publication date
EP3630350A1 (en) 2020-04-08
EP3630350A4 (en) 2021-03-31
KR20200027927A (ko) 2020-03-13
US10982276B2 (en) 2021-04-20
WO2018222853A1 (en) 2018-12-06
KR102583062B1 (ko) 2023-09-25
JP2020522257A (ja) 2020-07-30
US20190040459A1 (en) 2019-02-07

Similar Documents

Publication Publication Date Title
JP7277054B2 (ja) ホモポリマーコード化核酸メモリ
US11174512B2 (en) Homopolymer encoded nucleic acid memory
US20230264164A1 (en) Homopolymer encoded nucleic acid memory
CN102083998B (zh) 通过展开进行高通量核酸测序
Shendure et al. Overview of DNA sequencing strategies
CN107849598B (zh) 簇中的表面引物的增强利用
ES2889875T3 (es) Secuenciación a partir de cebadores múltiples para incrementar la velocidad y la densidad de los datos
CN106795554A (zh) 使用核苷酸可逆终止子的离子传感器dna和rna合成测序
WO2023196499A1 (en) Substrate cleavage for nucleic acid synthesis
Myllykangas et al. Overview of sequencing technology platforms
US20230313273A1 (en) Selecting aptamers using sequencing
US20240427528A1 (en) Compositions, systems, and methods for nucleic acid data storage
JP7710993B2 (ja) ホモポリマーエンコードされた核酸メモリ
WO2025054432A1 (en) Systems and methods for dna reading
KR20240026950A (ko) 3'-차단된 뉴클레오티드의 정제 및 중합
Chen DNA sequencing and short reads assembly
HK1246366B (en) Enhanced utilization of surface primers in clusters

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20210531

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20220328

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20220330

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20220627

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20220712

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20221031

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20230130

A524 Written submission of copy of amendment under article 19 pct

Free format text: JAPANESE INTERMEDIATE CODE: A524

Effective date: 20230324

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20230404

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20230504

R150 Certificate of patent or registration of utility model

Ref document number: 7277054

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150