KR102561068B1 - Hir cleaning composition containing Indirubin and Manufacturing Method Using Thereof - Google Patents

Abstract

The present invention relates to a solid shampoo bar containing indirubin, that is a plant extract with pharmacological action such as antibacterial, anti-inflammatory, and antioxidant action and to a manufacturing method thereof. More specifically, the present invention relates to a shampoo bar containing: a powder material including starch and a powdery surfactant; a liquid surfactant; a liquid material including indirubin oil extracted by stirring Niram in oil; and additives, wherein, based on 100 parts by weight of the powder material, 20 to 30 parts by weight of the liquid material and 2 to 3 parts by weight of the additives are mixed. The present invention increases the immunity of the scalp using indirubin, which is a plant extract with pharmacological action such as antibacterial, anti-inflammatory, and antioxidant action and exhibits antibacterial and anti-inflammatory action to be effective in hair root reinforcement, hair loss prevention, moisturization, fungus resistance, and sensitive scalp alleviation.

Description

Shampoo bar containing indirubin and manufacturing method thereof {Hir cleaning composition containing Indirubin and Manufacturing Method Using Thereof}

The present invention relates to a solid shampoo bar containing indirubin, a plant extract having pharmacological actions such as antibacterial, anti-inflammatory and antioxidant actions, and a method for manufacturing the same, and more particularly, to a liquid material containing indirubin obtained by oil extraction of nyram and It relates to a shampoo bar containing indirubin composed of powder materials and additives including starch and surfactant and a method for manufacturing the same.

Indigo is a representative blue dye plant and has been widely used since the longest time in human history. Ram in Chinese characters and indigo in English. In general, indigo is an old natural dye as a main component of natural indigo, and dyes produced from indigo and its isomers are collectively referred to as indigoid dyes. These natural extracts of indigo exist together with their various isomers, such as native indigo (Polygonumtinctorium), indigo (Indigofera tinctoria), wild water (Indigofera anil), plants of the genus Indigofera, Isatis tinctoria and Yoruba. It can be obtained from various plants, such as indigo (Lonchocarpus cyanescens), and is mainly obtained by fermenting the indica present in them. Among the plants that produce such indigo, P. tinctorium has long been used as a medicinal plant as well as a major source of blue dye.

Indigo reacts anthranilic acid with chloroacetic acid to produce phenylglycine-o-carboxylic acid, which is reacted with strong bases such as potassium hydroxide, sodium hydroxide, and sodium amide. It is industrially synthesized by heating in the presence of to produce indoxyl and oxidizing the aqueous solution through air.

However, unlike indigo, which is industrially synthesized in this way, other dyes such as indirubin, which is an isomer, are produced in small amounts as by-products in the industrial production process of indigo, and are not mass-produced.

In particular, indirubin is a reddish-purple pigment that generally exists together with indigo, and is also called indigo red. Indirubin is a shiny brown needle-like crystal that sublimates into red needle-like crystals. Indirubin is difficult to use because it has low solubility in water and is insoluble in water.

On the other hand, sweet potato (Ipomoea batatas L.) has recently been known as a health food, and its use as a subsidiary material of various foods is gradually expanding. Sweet potatoes contain a lot of dietary fiber, vitamins and minerals, and also contain a large amount of antioxidants such as phenolic compounds, anthocyanins, tocopherols, and β-carotene. Compared to sweet potato roots, sweet potato leaves or stems are less utilized and are insignificant.

It contains various physiologically active substances and antioxidants, so it shows various effects such as anti-aging, anti-cancer, anti-inflammatory, and immune function improvement, but after extraction, it is unstable and sometimes irritating, so it is often toxic to the human body. Many attempts have been made to increase the effect by stabilizing natural extracts, reducing toxicity, or converting them into stable derivatives, and fermentation is one of them. Fermentation is a process of decomposing organic matter using enzymes of microorganisms to produce substances useful for human life. Representative fermentation microorganisms that produce substances useful for the human body include lactic acid bacteria and yeast, and various foods are It is produced by a fermentation process. In addition to producing useful substances in fermentation, microorganisms involved in fermentation play a role in immunity and toxin removal in the intestine. Accordingly, efforts are being made to increase the utilization of sweet potato leaves or stems by obtaining stabilized antioxidants using sweet potato leaves or stems.

Meanwhile, the skin is composed of keratin, epidermis, dermis, and subcutaneous tissue, and functions to protect the human body from external factors or physical and chemical stimuli from the environment. Among them, the epidermis is the thinnest layer among the three skin structures, and as a function responsible for moisturizing and protecting the skin, studies on skin beauty are being actively conducted.

There are problems such as hair loss and deterioration of hair health due to various causes such as increased interest in hygiene of modern people, environmental pollution, and stress.

Soap is made by adding sodium hydroxide or potassium hydroxide called caustic soda to vegetable, animal, mineral oil (oil) ingredients, stirring well to coagulate, removing moisture from the coagulated material, It has a form of manufacturing in which it is put into a mold to create a shape.

It is prepared using caustic soda used in the manufacture of such soap, and lye, which is a strong alkali component, may cause skin burns by giving considerable irritation when in contact with weakly acidic skin. If you wipe your face after using the alkaline soap used in this way, you may feel a strong tightening sensation. It becomes dry, and due to the process of shrinking and clogging the pores, sebum secretion may be hindered.

Most people use a lot of chemical cleansers to cleanse and clean their skin, scalp, and hair, but their main ingredients are surfactants, foam enhancers, emulsifiers, thickeners, and additives such as preservatives. There is a possibility of irritation, and the treatment effect for hair damage as well as itching is low. In addition, since various types of soaps currently on the market use synthetic oil, for example, synthetic oils such as beef tallow, lard, fatty acids, and chemical components such as propylene glycol are artificially mixed with ethanol and paraffin wax, which is not environmentally friendly. In addition, it has been reported that it causes accumulation of dermal poison, which can be said to be the toxicity of petroleum-based chemicals, and causes atopy, skin cancer, hair loss, allergy, etc. when used for a long time.

Therefore, various hair care products are being developed for the purpose of promoting blood circulation, strengthening hair root function, moisturizing the scalp, preventing dandruff, antioxidant effect, and extending the hair growth period. There is a demand for the development of products containing herbal medicines that can be reduced.

Korean Patent Registration No. 10-2255269 Korean Patent Registration No. 10-2377359

The present invention is to solve the above problems, and an object of the present invention is to provide a method for preparing a shampoo bar using indirubin and a shampoo bar manufactured by the method.

An object of the present invention is to provide a shampoo bar containing indirubin capable of long-term scalp care with low toxicity and a manufacturing method thereof.

In addition, an object of the present invention is to provide a shampoo bar containing indirubin having a low risk of rancidity by containing sweet potato leaf and stem extracts and a manufacturing method thereof.

In order to achieve the above object, the present invention consists of a powder material including starch and a powdery surfactant, a liquid surfactant, and a liquid material and additives including indirubin oil extracted by stirring nyram into oil. It is characterized in that, compared to 100 parts by weight of the powder material, 20 to 30 parts by weight of the liquid material and 2 to 3 parts by weight of the additives are mixed.

The powder material is characterized by comprising 40 to 45 parts by weight of starch and 50 to 60 parts by weight of a surfactant.

The liquid material is characterized by comprising 80 to 95 parts by weight of a liquid surfactant and 1 to 25 parts by weight of indirubin oil.

The additive is characterized in that it comprises 2 to 5 parts by weight of glycerin, 1 to 2 parts by weight of vitamin E, 2 to 3 parts by weight of a moisturizer, and 1 to 2.5 parts by weight of 1,2-hexanediol.

The indirubin oil is obtained by drying nyram to a water content of 20 to 25% at 40 to 50 ° C, mixing the dried nyram with water, pulverizing the nyram to a particle size of 50 to 75 μm, mixing the pulverized nyram with oil, stirring, and aging. After filtering, it is characterized in that it is stirred by heating to 140 ~ 150 ℃.

The indigo plant is impregnated with a mixture of water and acetic acid having a pH of 3 to 4 and aged at 23 to 25 ° C for 36 to 48 hours. It is characterized in that it is a solid precipitate obtained by removing the liquid phase.

The liquid material is lyophilized and pulverized sweet potato leaves and sweet potato stems, then put in a culture medium in which Candida utilis is cultured and cultured at 30 to 40 ° C for 24 to 72 hours to make fermented sweet potato leaves and stems, 95% ethanol solvent was added to the fermented sweet potato leaves and stems in an amount of 20 times the volume of fermented sweet potato leaves and stems, extracted at room temperature, filtered, concentrated under reduced pressure, and diluted with purified water. 2 to 5 weight of sweet potato leaf and stem extracts It is characterized in that it is configured to further include a part.

Step 1 of fermenting indigo plant to produce nyram; Step 2 of preparing indirubin oil by stirring nyram into oil; A third step of preparing a solid shampoo bar by mixing the indirubin oil with a powder material including starch and a powdered surfactant, a liquid material including a liquid surfactant, and additives; and 100 weight of the powder material It is characterized in that it is mixed with 20 to 30 parts by weight of liquid material and 2 to 3 parts by weight of additives.

The additive is characterized in that it comprises 2 to 5 parts by weight of glycerin, 1 to 2 parts by weight of vitamin E, 2 to 3 parts by weight of a moisturizer, and 1 to 2.5 parts by weight of 1,2-hexanediol.

In the first step, the indigo plant is impregnated with a mixture of water and acetic acid of pH 3 ~ 4 and aged at 23 ~ 25 ℃ for 36 ~ 48 hours. After that, the liquid phase is removed and Niram is prepared.

The second step is to dry the nyram at 40 ~ 50 ℃ to a moisture content of 20 ~ 25%, mix the dried nyram with water and pulverize it to a particle size of 50 ~ 75, mix the pulverized nyram with oil, stir, and filter after aging. And, it is characterized by heating to 140 ~ 150 ℃ and stirring to produce indirubin oil.

In the third step, 80 to 95 parts by weight of liquid surfactant and 1 to 25 parts by weight of indirubin oil are included as the liquid material, and sweet potato leaves and sweet potato stems are lyophilized and pulverized, and then Candida utilis is cultured It was put in one medium and cultured at 30 ~ 40 ℃ for 24 ~ 72 hours to make fermented sweet potato leaves and stems, and to the fermented sweet potato leaves and stems, 95% ethanol solvent was added in an amount 20 times the volume of fermented sweet potato leaves and stems. Extracted at room temperature, filtered and concentrated under reduced pressure, characterized in that it further comprises 2 to 5 parts by weight of sweet potato leaf and stem extract diluted with purified water.

The present invention increases the immunity of the scalp by using indirubin, a plant extract with antibacterial, anti-inflammatory, and antioxidant pharmacological actions, and exhibits antibacterial and anti-inflammatory effects to strengthen hair roots, prevent hair loss, moisturize, antifungal, and relieve sensitive scalp. It works.

In addition, the present invention is effective in improving scalp psoriasis by mixing nyram with oil and heating the aged nyram and oil mixture at a high temperature to include indirubin, which is low-toxic and capable of long-term scalp care with low irritation to the skin. .

In the present invention, the oxidation stability of a shampoo bar containing indirubin is improved by antioxidant activity by containing sweet potato leaf and stem extracts.

1 is a manufacturing process diagram of a shampoo bar containing indirubin according to an embodiment of the present invention;
2 is a photograph showing a shampoo bar containing indirubin oil and indirubin according to an embodiment of the present invention.

Hereinafter, the present invention will be described in detail. Terms used in this specification should be interpreted as generally understood by those skilled in the art unless otherwise defined. The drawings and embodiments in this specification are for those skilled in the art to easily understand and practice the present invention, and contents that may obscure the subject matter of the invention in the drawings and embodiments may be omitted, and the present invention is shown in the drawings and embodiments. is not limited to

In addition, in the following description of the embodiments of the present invention, for parts that are the same as or similar to the contents of the prior art or are determined to be easily understood and implemented at the level of those skilled in the art, the detailed descriptions are provided to simplify the description. It should be noted that .

Hereinafter, with reference to the accompanying drawings, a shampoo bar containing indirubin rich in saponin according to the present invention and a manufacturing method thereof will be described in detail.

1 is a manufacturing process diagram of a shampoo bar containing indirubin according to an embodiment of the present invention, Figure 2 is a shampoo bar containing indirubin oil (a) and indirubin (b) according to an embodiment of the present invention This is a photo that shows

The shampoo bar containing indirubin according to the present invention comprises a powder material including starch and a powdery surfactant, a liquid surfactant, and a liquid material and additives including indirubin oil extracted by stirring nyram into oil. It consists of, and is mixed with 20 to 30 parts by weight of liquid material and 2 to 3 parts by weight of additives compared to 100 parts by weight of the powder material.

The powder material includes starch and a powdery surfactant, and is composed of 40 to 45 parts by weight of starch and 50 to 60 parts by weight of surfactant.

Starch is a high-molecular carbohydrate in which several glucoses are linked by glucosidic bonds and has viscosity, so it is processed into a solid shampoo bar shape. When starch is added in an amount of less than 40 parts by weight, processing into a solid is not smooth, and when starch is added in an amount exceeding 45 parts by weight, foaming is reduced during use. Starch contains cornstarch and allantoin.

Allantoin is a natural substance extracted from perennials such as camphor, oak, and wheat sprouts. Allantoin removes dead skin cells, softens the skin by giving moisture to the skin, and promotes cell proliferation to help heal wounds on the skin.

Cornstarch is a starch obtained from corn, which keeps the ingredients together well and prevents them from separating after completion. It has the effect of adsorbing sebum and waste.

As a powder material, the surfactant is in a powder form and includes sodium cocoyl isethionate, glyceryl stearate, and sorbitan olivate. Sodium cocoyl isethionate is a natural surfactant derived from coconut to replace animal surfactant sodium salt, and is a sodium salt of a condensate of palm oil fatty acid and isethionic acid. It has a cleansing and moisturizing effect. Sodium cocoyl isethionate is mildly (slightly) acidic with a pH of 4.5 to 6.0 and provides rich foam while being hypoallergenic. When used together with the apple wash described later, the cleaning power is further enhanced.

Glyceryl stearate is a natural ingredient based on coconut and soybean oil, and is an emulsifier as a mixture of lipophilic glyceryl stearate and other surfactants. It is less irritating to the skin and acts as an emollient on the skin surface to make the skin soft and smooth. It also forms a barrier on the skin surface to slow down the loss of moisture from the skin. It forms a film on the skin and has the function of storing moisture, preventing dryness and promoting skin absorption of active ingredients.

Sorbitan Olivate is a monoester component of hexitol anhydride derived from sorbitol and fatty acid derived from olive oil.

Next, the liquid material is composed of a liquid surfactant and indirubin oil extracted by stirring nyram into oil.

Liquid surfactants can be used by mixing anionic surfactants and natural surfactants. Apple wash is a natural surfactant. Apple wash does not denature skin proteins and is a natural surfactant without preservatives, so there is little irritation even to sensitive skin. Anionic surfactants include olive liquid and potassium cocoyl glycinate, and the surfactant is included in 80 to 95 parts by weight based on the total weight of the liquid material.

On the other hand, indirubin is extracted by stirring nyram into oil, and indirubin oil and liquid surfactant are contained in 20 to 30 parts by weight of liquid material based on 100 parts by weight of powder material.

The liquid material is composed of 80 to 95 parts by weight of a liquid surfactant and 1 to 25 parts by weight of indirubin oil.

The indirubin oil is obtained by drying nyram to a water content of 20 to 25% at 40 to 50 ° C, mixing the dried nyram with water, pulverizing the nyram to a particle size of 50 to 75 μm, mixing the pulverized nyram with oil, stirring, and aging. After filtering, heated to 140 ~ 150 ℃ and stirred.

The aged indirubin oil is heated to 140 ~ 150 ℃ and stirred for 30 minutes to oxidize. The heated and oxidized indirubin oil is filtered, left at room temperature for about 12 hours, and filtered under reduced pressure to extract red, high-quality indirubin oil.

At least one selected from among 1,2-hexanediol and 1,3-butylene glycol is added to the indirubin oil for antiseptic and antibacterial properties.

On the other hand, the indigo plant is impregnated with a mixture of water and acetic acid of pH 3 ~ 4 and aged at 23 ~ 25 ℃ for 36 ~ 48 hours. It is a solid precipitate obtained after removing the liquid phase.

The liquid material is lyophilized and pulverized sweet potato leaves and sweet potato stems, then put in a culture medium in which Candida utilis is cultured and cultured at 30 to 40 ° C for 24 to 72 hours to make fermented sweet potato leaves and stems, 95% ethanol solvent was added to the fermented sweet potato leaves and stems in an amount of 20 times the volume of fermented sweet potato leaves and stems, extracted at room temperature, filtered, concentrated under reduced pressure, and diluted with purified water. 2 to 5 weight of sweet potato leaf and stem extracts It consists of more parts.

Sweet potato leaves and stems contain many antioxidants, including anthocyanins, polyphenols, flavonoids and caffeic acid derivatives. When a large amount of vegetables or fruits containing antioxidants such as carotenoids, flavonoids, and polyphenols are consumed, the effect of suppressing the occurrence of cardiovascular disease or cancer and suppressing inflammatory reactions is known.

Sweet potato leaves and stems are harvested, washed, freeze-dried, and finely pulverized using a crusher. To obtain an ethanol extract, the sweet potato leaves and stems are freeze-dried and pulverized, put into a medium in which microorganisms are cultured, and kept at 30 to 40 ° C for 24 Incubate for 72 hours.

Fermentation can be selectively transformed using microorganisms to produce useful products. Microorganisms used for fermentation of sweet potato leaf and stem extracts of the present invention are Bacillus subtilis, Lactobacillus plantarum, Lactobacillus casei, Candida utilis It is selected from the group consisting of and fermented sweet potato leaves and stems.

Harvested, washed and dried sweet potato leaves and stems were placed in a medium in which the microorganism was cultured and cultured at 30 to 40 ° C for 24 to 72 hours to make fermented sweet potato leaves and stems, and 95% ethanol solvent was added to the fermented sweet potato leaves and stems. is added in an amount of 20 times the volume of fermented sweet potato leaves and stems. Then, sweet potato leaf and stem extracts are extracted at room temperature for 1 to 5 weeks. After filtering, the mixture is concentrated under reduced pressure to remove the solvent. Sweet potato leaf and stem extracts are prepared by diluting by adding 2.5 parts by weight of purified water to 1 part by weight of the extract concentrated under reduced pressure. The fermented sweet potato leaf and stem extract has excellent antioxidant activity by fermentation at pH 3.5 to pH 9, preferably pH 4 to pH 6, and the antioxidant activity of sweet potato leaf and stem extract is The oxidation stability of shampoo bars containing indirubin is improved.

Additives are further mixed with the powder material and the liquid material.

The additives include 2 to 5 parts by weight of glycerin, 1 to 2 parts by weight of vitamin E, 2 to 3 parts by weight of a moisturizer, and 1 to 2.5 parts by weight of 1,2-hexanediol.

The additive further comprises 1 to 2.5 parts by weight of essential oil.

Glycerin is a natural moisturizer that absorbs into hair and remains even after rinsing, providing a moisturizing effect. Glycerin is added in 2 to 5 parts by weight. When added in less than 2 parts by weight, the moisturizing effect is insignificant, and when added in excess of 5 parts by weight, there is a problem in that a large amount of glycerin is adsorbed to the hair and the hair becomes sticky.

Vitamin E has an antioxidant function and is added in 1 to 2 parts by weight. Vitamin E is a type of fat-soluble vitamin and suppresses the action of active oxygen to suppress oxidation of various cells such as skin and blood vessels. When vitamin E is added in an amount of less than 1 part by weight, the antioxidant effect is insignificant, and when added in an amount exceeding 2 parts by weight, the cost becomes excessive. In addition to vitamin E, vitamins that can be added include vitamin A and its derivatives, vitamin B1 and its derivatives, vitamin B2 and its derivatives, vitamin B6 hydrochloride, vitamin B6 tripalmitate, vitamin B6 dioctanoate, vitamin B12, B vitamins such as vitamin B15 and its derivatives, α-tocopherol, β-tocopherol, γ-tocopherol, vitamin E such as vitamin E acetate, vitamin D, vitamin H, pantothenic acid, pantethine, vitamin F, bioflavonoids such as vitamin K, rutin, hesperidin, and naringin, and derivatives thereof; derivatives thereof, such as vitamin U, ferulic acid, α-lipoic acid orotic acid, and coenzyme Q10; and salts thereof may be included. .

Moisturizers are added in 2 to 3 parts by weight. One or more moisturizers selected from glycerin, propylene glycol, sodium hyaluronate, and the like are added. Examples of humectants include glycerin, erythritol, xylitol, maltitol, glycerin, propylene glycol, 1,3-butylene glycol, sorbitol, maltitol, polyglycerin, polyethylene glycol, dipropylene glycol, 1,2-pentanediol, and isoprene. Polyhydric alcohols such as glycol, glycoose, maltose, trehalose, saccharide derivatives of trehalose, dextrins, cyclodextrins, branched cyclodextrins, cyclonigerosylnigerose, cyclomaltosylmaltose, sugars, amino acids, Peptides, sodium lactate, sodium pyrrolidonecarboxylate, xyloglucan, quince seed, carrageenan, pectin, mannan, cadran, galactan, dermatan sulfate, glycogen, keratan sulfate, chondroitin, chondroitin sulfate, mucoy water-soluble polymer substances such as tin sulfate, kerato sulfate, locust bean gum, succinoglucan, caronic acid, hyaluronic acid, heparan sulfate, sodium hyaluronate, collagen and mucopolysaccharide, silicones such as dimethylpolysiloxane and methylphenylsiloxane; Cultured supernatant of lactic acid bacteria and bifidobacteria, eucalyptus, hops, ginger, Uncaria gambier Roxburgh, rosa polyantha, horse chestnut, adlay, cattail, loquat tree, ginseng, bubble gum , plant extracts such as birch, mountain hydrangea, clove tree, safflower, cucumber plant, white iris, linden tree, hamamelis, peony and arborvitae, etc. can be exemplified. Among them, trehalose having a strong moisturizing effect, saccharide derivatives of trehalose, cyclic tetrasaccharides, hyaluronic acid and its salts, chondroitin sulfate and its salts are used alone or in combination of two or more. it is desirable

On the other hand, as a thickener, polyoxyethylene derivatives, glycerin fatty acid esters, sucrose fatty acid esters, sorbitan fatty acid esters, propylene glycol fatty acid esters, surfactants such as lecithin, carboxyvinyl polymers, xanthan gum, carboxymethyl cellulose, carboxymethyl cellulose sodium salts, hydra At least one selected from the group consisting of hydroxypropyl cellulose, hydroxypropyl methyl cellulose, sodium palm kernelate, sodium tallowate, and sodium palmate may be added.

Meanwhile, 1,2-hexanediol is mixed in an amount of 1 to 2.5 parts by weight. 1-2 Hexanediol is not a preservative, but it serves as a preservative and is used as a solvent. Unlike other preservatives, it has little toxicity and does not significantly affect cosmetic formulations. It also mixes well with water and has excellent moisturizing and antibacterial properties.

Essential oils are included in 1 to 2.5 parts by weight, and antibacterial natural fragrances include grapefruit, neroli, niauli, lavender, lime, lemon, lemongrass, lemon balm, rose, rosemary, rosewood, linden blossom, marjoram, mandarin, and myrtle. , myrrh, violet, basil, verbena, birch, bergamot, bay, vetiver, benzoin, cypress, sandalwood, cinnamon, cedarwood, citronella, orange, eucalyptus, ylang ylang, jasmine, geranium, juniper berry, ginger, It can be used by selecting one or more from the group consisting of cardamom, chamomile, cayuput, camphor, clary sage, thyme, tangerine, tea tree, palmarosa, patchouli, pettigren, peppermint, hyssop, and frankincense. When the essential oil is included in an amount of less than 1 part by weight, the addition effect is insignificant, and when the essential oil is added in an amount exceeding 2.5 parts by weight, the scalp is stimulated and the cost becomes excessive.

Hereinafter, a process for manufacturing a shampoo bar containing indirubin according to the present invention will be described with reference to FIG. 1 .

The method for producing a shampoo bar containing indirubin of the present invention includes a first step of fermenting indigo plant to produce nyram; Step 2 of preparing indirubin oil by stirring nyram into oil; 3 steps of preparing a solid shampoo bar by mixing the indirubin with starch, a powder material containing a powdered surfactant, a liquid material containing a liquid surfactant, and an additive, compared to 100 parts by weight of the powder material , 20 ~ 30 parts by weight of liquid material and 2 ~ 3 parts by weight of additives are mixed and used.

When mixing less than 20 parts by weight of liquid material compared to 100 parts by weight of powder material or mixing in excess of 30 parts by weight, it is difficult to mold solid shampoo soap. More preferably, 27 parts by weight of the liquid material is mixed with 100 parts by weight of the powder material.

Additives are mixed in 2 to 3 parts by weight based on 100 parts by weight of the powder material, more preferably 2.5 parts by weight.

In the first step, indigo is fermented to produce nyram.

As a method of manufacturing nyram, the indigo is harvested first, washed with water at room temperature, and weeds are removed. Next, put the indigo plant in a container for extraction, press down the indigo plant so that it does not float on top of the water, and mix water and acetic acid to submerge the indigo plant. Indigo should not float in water so that it is not contaminated by germs. The mixture of water and acetic acid is set to pH 3 ~ pH 4, and through this, the color of indigo is excellently extracted.

After that, it is aged for 36 to 48 hours at a temperature of 23 to 25 ° C. When the salt solution (indigo water) becomes a deep jade color, the indigo plant is removed, and the acidity of the aged salt solution is measured to maintain pH 3 ~ pH 4. At this time, the acidity is adjusted while adding acetic acid. If acetic acid is added, the red color deepens, and if acetic acid is reduced, the color becomes closer to purple.

Dissolve the shell flour (clam powder) in the aged salt solution (indigo water) and stir for more than 4 hours using a mixer to combine the salt solution and pan flour. Oxygen is supplied during the stirring process to combine the salt solution and pan powder. Cheongdae, the primary product of the indigo dye manufacturing process, is a very light, fine blue particle that is produced in very small quantities. After that, if you continue to stir, the bubbles fade to white, the color of the water is oxidized to dark blue, and the indigo pigment combined with shell dust sinks into insoluble particles, indigotin, and begins to separate from the upper water. After settling for about 24 hours, the upper water is discarded, and the submerged indigo pigment is put on a filter and filtered for 3 to 4 hours to drain the water. A well-filtered nyram is useful because it has little specific odor and no impurities.

At this time, 0.9 ~ 1.2 kg of shell powder is added to 200L of the indigo water. If the shell content is less than 0.9 kg, there is a problem in that the recovery rate of the pigment dissolved in water is lowered, and if the shell content exceeds 1.2 kg, the color of the obtained nyram becomes pale and the content of indigo pigment is lowered.

On the other hand, in the process of manufacturing niram, surfactants, preservatives (antibacterial agents), humectants, thickeners, water-soluble polymers, antioxidants, chelating agents, One or two or more selected from pigments, flavors, pH adjusters, vitamins containing L-ascorbic acid or derivatives thereof, and additives may be added. In addition, there is no particular limitation on the addition timing or addition amount of these components, as long as the effect of the present invention is not hindered, and they are added at any time in the extraction step.

The second step is to prepare indirubin oil by stirring nyram into oil.

First, the niram is dried to a moisture content of 20 to 25% in a drying room by maintaining a temperature of 40 ~ 50 ℃. Next, the dried nyram and water are mixed and pulverized for 48 to 72 hours to collect nyram having a particle size of 50 to 75 μm. If the particle diameter of niram is less than 50 μm, the filtration rate decreases, and if the particle diameter of niram exceeds 75 μm, the niram is lost during filtration. The collected niram is screened through a vibrating screen to sort out those with a particle diameter of more than 75 μm.

The selected niram is mixed with oil, stirred at room temperature for about 1 hour, and precipitated to separate the supernatant. This process is repeated twice. 5 to 20 parts by weight of Niram is mixed with 100 parts by weight of the oil. More preferably, 10 to 15 parts by weight of nyram is mixed with 100 parts by weight of oil. The supernatant is separated and aged in a refrigerator to maintain acidity. The acidity is maintained to remove the supernatant suspension and extract high quality indirubin oil.

After the aging, a heating process is performed to increase indirubin extraction, and it is preferable to use oil with a high smoke point so that there is no risk of rancidity of the oil. In order to extract oil, indirubin is heated to 140 ~ 150 ° C. to sublimate with air. When exposed to high heat, there is a risk of rancidity of the oil, so it is preferable to use oil with a high smoke point. Since oil with a low smoke point has a problem with rancidity, indirubin oil is prepared by mixing and heating refined olive oil, sunflower oil, coconut oil, camellia oil, palm oil, avocado oil, etc. with high smoke point. Preferably, extra olive oil is used.

The aged indirubin oil is heated to extract indirubin. The aged indirubin oil is heated to 140 ~ 150 ℃ and stirred for 30 minutes to oxidize. As time passes, indirubin is extracted as it changes from blue to purple. When indirubin oil is heated to less than 140 ° C, indirubin extraction is insufficient, and when heated to more than 145 ° C, irritants are produced due to acidification of the oil, and the smoke point decreases and the viscosity increases.

The heated and oxidized indirubin oil is filtered, left at room temperature for about 12 hours, and filtered under reduced pressure to extract red, high-quality indirubin oil.

At least one selected from among 1,2-hexanediol and 1,3-butylene glycol is added to the indirubin oil for antiseptic and antibacterial properties.

The third step is a step of preparing a solid shampoo bar by mixing the indirubin with starch, a powder material including a powdery surfactant, a liquid material including a liquid surfactant, and additives.

First, prepare the ingredients for the shampoo bar. It is composed of a powder material including starch and a powder surfactant, a liquid surfactant, and a liquid material and additives including indirubin oil extracted by stirring nyram into oil, relative to 100 parts by weight of the powder material, liquid phase Weigh 20 to 30 parts by weight of the material and 2 to 3 parts by weight of the additive, and mix the above materials.

More specifically, surfactant powders of sodium cocoyl isethionate and glyceryl stearate were mixed with cornstarch and allantoin powders, and apple amino acid, potassium cocoyl glycinate, and olive liquid (PEG-7) were used as liquid ingredients. 20 to 30 parts by weight of the liquid surfactant is measured based on 100 parts by weight of the powder material.

80 to 95 parts by weight of a liquid surfactant and 1 to 25 parts by weight of indirubin oil as the liquid material, freeze-dried and pulverized sweet potato leaves and sweet potato stems, and then added to a culture medium in which Candida utilis was cultured Incubation at 30 ~ 40 ℃ for 24 ~ 72 hours to make fermented sweet potato leaves and stems, and to the fermented sweet potato leaves and stems, 95% ethanol solvent was added in an amount of 20 times the volume of fermented sweet potato leaves and stems, extracted at room temperature, , It is composed of further comprising 2 to 5 parts by weight of sweet potato leaf and stem extract diluted with purified water after filtration and concentrated under reduced pressure. By using sweet potato leaves and stems, which are insignificantly used, the antioxidant activity of sweet potato leaf and stem extracts improves the oxidation stability of shampoo bars containing indirubin.

After mixing the powder material and the liquid material, indirubin oil, vitamin E, and 1,2-hexanediol are added, the first kneading is performed for 15 to 20 minutes. The vitamin E and 1,2-hexanediol impart antiseptic effects and antibacterial properties. In order to prevent the shampoo bar from shrinking in the first kneaded material, a second kneading is performed by adding sodium palm kernelate derived from palm kernel oil as a thickener. The second dough is kneaded for 5 to 10 minutes. The second kneaded material is matured for 60 to 120 minutes at room temperature in a sealed room to activate the ingredients of indirubin oil. While pushing the matured kneaded material into the injection machine, it is automatically cut in fixed quantities. The injection process may be repeated 2 to 4 times, and a shampoo bar in which hard and dense foam is produced is manufactured through the repeated injection process. More preferably, the repeated injection process is performed three times.

The mixture cut in the above quantity is put into a molding machine and a shampoo bar of a desired shape is stamped out.

Thereafter, after drying at 40 ° C. for 45 hours with a low-temperature dryer, it is taken out, dried at room temperature for 4 to 5 days, and then packaged to prepare shampoo.

The primary irritation test by skin patch was performed on 33 subjects for the shampoo bar containing indirubin according to the present invention, and the skin patch test was performed on 32 study subjects, except for one dropout. After diluting 1% of the shampoo bar containing indirubin according to the present invention in sterilized distilled water, loading 20 μl using a pipette into a 1 cm × 1 cm product category (IQ Ultimate ^TM ), fixing it on the skin, and then fixing it on the skin for 24 hours attached to. The first visual evaluation by a dermatologist was conducted 30 minutes after the patch was removed, and the second visual evaluation was conducted 24 hours after the patch was removed.

Visual evaluation was based on PCPC (Personal Care Products Council) Safety Testing Guidelines and ICDRG (International Contract Dermatitis Research Group) criteria. Based on this, the skin irritation index was calculated, and the skin irritation was evaluated with reference to the skin irritation index table, and the results are shown in Table 1.

The skin irritation index calculation formula is as follows.

The skin patch test result judgment table is as follows.

The skin types of the study subjects were 19 neutral and 13 dry, and as a result of the judgment, the skin irritation index of the shampoo bar containing indirubin oil of the present invention was 0.00, which was confirmed to be mild.

Claims (11)

Consisting of powder materials including starch and powdery surfactants, liquid surfactants, liquid materials and additives including indirubin oil extracted by stirring nyram into oil,
Compared to 100 parts by weight of the powder material, 20 to 30 parts by weight of liquid material and 2 to 3 parts by weight of additives are mixed,
The powdered material is
It is composed of 40 to 45 parts by weight of starch and 50 to 60 parts by weight of surfactant,
The liquid material is
It is composed of 80 to 95 parts by weight of a liquid surfactant and 1 to 25 parts by weight of indirubin oil,
The indirubin oil is
Dry the niram at 40 ~ 50 ℃ to a moisture content of 20 ~ 25%,
Mix the dried nyram with water and pulverize it to a particle size of 50 ~ 75 μm,
The pulverized nyram was mixed with oil, stirred, filtered after aging,
Shampoo bar containing indirubin, characterized in that heated to 140 ~ 150 ℃ and stirred. delete delete According to claim 1,
The additives
A shampoo bar containing indirubin, characterized in that it is composed of 2 to 5 parts by weight of glycerin, 1 to 2 parts by weight of vitamin E, 2 to 3 parts by weight of a moisturizer, and 1 to 2.5 parts by weight of 1,2-hexanediol. delete According to claim 1,
The above niram is
Indigo is impregnated in a mixed solution of water and acetic acid of pH 3 ~ 4 and aged at 23 ~ 25 ℃ for 36 ~ 48 hours. After removing the indigo plant, the remaining matured salt solution of pH 3 ~ 4 is mixed with shell meal, stirred, and the liquid phase is removed. A shampoo bar containing indirubin, characterized in that it is a solid precipitate obtained by doing. According to claim 1,
The liquid material is
Sweet potato leaves and sweet potato stems are lyophilized and pulverized, put in a culture medium in which Candida utilis is cultured, and cultured at 30 to 40 ° C for 24 to 72 hours to make fermented sweet potato leaves and stems, 95% ethanol solvent was added to the fermented stem product in an amount of 20 times the volume of the fermented sweet potato leaf and stem, extracted at room temperature, filtered and concentrated under reduced pressure, diluted with purified water, and 2 to 5 parts by weight of sweet potato leaf and stem extract Shampoo bar containing indirubin, characterized in that the composition. Step 1 of fermenting indigo plant to produce nyram;
Step 2 of preparing indirubin oil by stirring nyram into oil;
A third step of preparing a solid shampoo bar by mixing the indirubin oil with starch, a powder material including a powdery surfactant, a liquid material including a liquid surfactant, and additives; and
The first step is
Indigo is impregnated in a mixed solution of water and acetic acid of pH 3 ~ 4 and aged at 23 ~ 25 ℃ for 36 ~ 48 hours. After removing the indigo plant, the remaining matured salt solution of pH 3 ~ 4 is mixed with shell meal, stirred, and the liquid phase is removed. and made neram,
The second step is
Dry the niram at 40 ~ 50 ℃ to a moisture content of 20 ~ 25%,
Water was mixed with the dried nyram and pulverized to a particle size of 50 ~ 75 μm,
The pulverized nyram was mixed with oil, stirred, filtered after aging,
Heating and stirring to 140 ~ 150 ℃ to prepare indirubin oil,
Shampoo bar manufacturing method containing indirubin, characterized in that mixed with 20 to 30 parts by weight of liquid material and 2 to 3 parts by weight of additives compared to 100 parts by weight of the powder material. delete delete According to claim 8,
The above 3 steps are
with the liquid material
80 to 95 parts by weight of liquid surfactant, 1 to 25 parts by weight of indirubin oil,
Sweet potato leaves and sweet potato stems are lyophilized and pulverized, put in a culture medium in which Candida utilis is cultured, and cultured at 30 to 40 ° C for 24 to 72 hours to make fermented sweet potato leaves and stems, 95% ethanol solvent was added to the fermented stem product in an amount of 20 times the volume of the fermented sweet potato leaf and stem, extracted at room temperature, filtered and concentrated under reduced pressure, diluted with purified water, and 2 to 5 parts by weight of sweet potato leaf and stem extract Method for producing a shampoo bar containing indirubin, characterized in that the configuration.