KR102540005B1 - Diagnostic strip manufacturing device - Google Patents

Abstract

The present invention relates to an apparatus for manufacturing a diagnostic strip, wherein a flat part is formed on both sides of the flat part, both side walls of which are formed symmetrically on both sides of the flat part and long holes are formed in the longitudinal direction, and a plurality of rail grooves are formed on the upper part of the flat part in the longitudinal direction. body to be; It consists of a rod coupled to both sides of the long hole of both side walls, a plurality of fixtures formed on the rod and inserted into the rail groove, and a drive unit that moves the rod to move forward and backward along the long hole, and the plurality of fixtures A pad holding unit to ensure that the fabric is in close contact with each other; A rotation rod connecting both side walls of the main body, a lower portion connected to the rotation rod and a pad attachment surface formed on the upper portion to attach the pad to one side of the fabric while being rotated; It is mounted on the end of the flat part of the main body and is mounted on the pad holding part, and the cutting part is formed with a cutter blade to cut the conveyed fabric into a certain width.

Description

Diagnostic strip manufacturing device {Diagnostic strip manufacturing device}

The present invention relates to a device for manufacturing a diagnostic strip, and more particularly, to a device that can perform cutting in the horizontal and vertical directions, attachment of a diagnostic pad, and application of reagents in one device, so that it can be conveniently and conveniently used in research institutes and universities. It relates to a diagnostic strip manufacturing apparatus capable of mass-producing diagnostic strips.

Recently, diagnostic strips for diagnosing diseases such as hepatitis, diabetes, anemia, hyperlipidemia, AIDS, etc., or pregnancy using bodily fluids such as urine or blood have been widely used. The diagnostic strip may include a diagnostic strip capable of diagnosing a disease or pregnancy by absorbing the bodily fluid.

In the diagnostic strip, a base card made of plastic and bonding pads, absorbent pads, membrane pads, and sample pads may be attached to the base card through adhesive.

The diagnostic strip may have a bar shape having a predetermined width, and may be obtained by cutting an approximately rectangular diagnostic card. The diagnostic strip may be manufactured by inserting the diagnostic strip into a housing having an opening.

However, in the method of manufacturing the conventional diagnostic kit described above, it is common that the reagent kit is supplied manually to the cutting machine, and productivity is remarkably high as transport or packaging is performed in a separate work process even after cutting. There was a problem with it falling off.

In order to solve these problems, automation equipment has been manufactured and used in the past, but the structure of the equipment is complicated and the productivity is also low due to the problem of poor interconnection.

In view of these conventional problems, Korean Patent Registration No. 1220279 "Diagnosis Kit Production System" has been proposed. a reagent kit supply unit; a cutting unit which cuts the reagent kits supplied from the reagent kit supply unit at regular intervals to form diagnostic kits and discharges them; a transport unit for taking out and transporting the diagnostic kit cut and discharged from the cutting unit; an alignment unit for aligning the diagnostic kits transferred from the transfer unit after being transferred by the guide means; It has a structure including a storage unit for storing the diagnostic kit that has passed through the alignment unit in a packaging container.

The conventional "diagnostic kit production system" described above is designed to simply perform only the process of cutting the diagnostic kit, so that the diagnostic kit without reagents is pre-manufactured and prepared in another space, and then the reagents are applied and cut to increase productivity. In addition, there is a problem of contamination of the kit when transferring the kit to which the diagnostic pad is attached for reagent application, and it is difficult to apply the reagent to the cut kit. There are many reagents that are excessively discarded, and thus the problem of over-consumption of reagents remains.

In addition, pharmaceutical companies, as well as research institutes and universities, have to purchase and use several pieces of equipment such as a pad attachment device, an indicator application device, and a pad cutting device in order to manufacture diagnostic sheets in the past, and excessive expenditure and multiple equipment There is a problem such as an excessive area required to install in one place.

In the present invention, a plurality of pads are adhered to fabric, and a reagent is discharged in a more precise and uniform amount to the area between the plurality of pads to form a reagent strip in a line shape, and then the fabric is cut into a predetermined size to form a strip. Its object is to provide an apparatus for manufacturing a diagnostic strip to be discharged.

Another object of the present invention is a diagnostic strip manufacturing device that can mass-produce diagnostic strips simply and conveniently at a research institute or university while preventing the inconvenience of having to purchase and use several pieces of equipment separately and the resulting excessive expenditure. is providing

The object of the present invention described above, a main body having a plane portion formed on the upper side, symmetrically formed on both sides of the plane portion and long holes formed in the longitudinal direction, and a plurality of rail grooves formed in the longitudinal direction on the upper portion of the plane portion; It consists of a rod coupled to both sides of the long hole of both side walls, a plurality of fixtures formed on the rod and inserted into the rail groove, and a drive unit that moves the rod to move forward and backward along the long hole, and the plurality of fixtures A pad holding unit to ensure that the fabric is in close contact with each other; A rotation rod connecting both side walls of the main body, a lower portion connected to the rotation rod and a pad attachment surface formed on the upper portion to attach the pad to one side of the fabric while being rotated; It can be achieved by an apparatus for manufacturing a diagnostic strip including a cutting part mounted on the end of the flat part of the main body and formed with a cutter blade that is mounted on the pad holding part and cuts the conveyed fabric to a certain width.

The pad receiving portion includes a flat panel, a plurality of protrusions formed on one end of the panel in the width and length direction, a plurality of air intake holes formed on one side of each protrusion, and a vacuum passage formed inside the panel and communicating with the intake holes. and a vacuum pump connected to the vacuum passage to generate a vacuum suction force.

A reagent injection unit mounted on one side wall of the main body and formed on one side of the rail groove, wherein the reagent injection unit includes a mounting table mounted on one side wall of the main body, a mounting rod coupled to the mounting table, and A bracket connected to the mounting rod and movable along the mounting rod, a connecting rod vertically coupled to the lower part of the bracket, a nozzle mounted on the lower end of the connecting rod, a hose connected to the nozzle, and the hose It is characterized in that it includes a reagent container connected to one side wall, a piston coupled to the inside of the reagent container, and a pressurizing unit for inhaling or discharging a drug through a nozzle by raising or lowering the piston.

The pressing unit is characterized in that a motor or a pneumatic cylinder.

The bracket is characterized in that a screw shaft screwed with the connecting rod is formed, and a handle gauge is formed on the screw shaft to adjust the elevation height of the bracket so that the height of the nozzle is adjusted.

and a stopper screwed to the mounting table and composed of a screw shaft and a screw head that are fixed or spaced apart from the mounting rod to exert a fixing force.

According to the present invention, a reagent strip is formed in a line shape by dispensing a reagent in a more precise and uniform amount in the area between a plurality of pads, and then the fabric is cut at specific intervals to mass-produce strip-type diagnostic kits. there is

1 is a perspective view showing an apparatus for manufacturing a diagnostic strip according to the present invention;
2 is a perspective view showing a state in which a control unit is removed from the apparatus for manufacturing a diagnostic strip according to the present invention;
3 is a partially enlarged front view of a 'pad storage unit' in the apparatus for manufacturing a diagnostic strip according to the present invention;
4 is an enlarged view of the pad storage unit in FIG. 3;
Figure 5a is a front view showing the operation of the pad storage unit in Figure 3;
Figure 5b is an enlarged view of the main part of Figure 5a;
6 is an enlarged perspective view of a 'reagent injection unit' in the apparatus for manufacturing a diagnostic strip according to the present invention;
7 is an enlarged perspective view of a main part of FIG. 6;

Hereinafter, embodiments will be described in detail with reference to the accompanying drawings. However, since various changes can be made to the embodiments, the scope of the patent application is not limited or limited by these embodiments. It should be understood that all changes, equivalents or substitutes to the embodiments are included within the scope of rights.

Specific structural or functional descriptions of the embodiments are disclosed for illustrative purposes only, and may be modified and implemented in various forms. Therefore, the embodiments are not limited to the specific disclosed form, and the scope of the present specification includes changes, equivalents, or substitutes included in the technical spirit.

Although terms such as first or second may be used to describe various components, such terms should only be construed for the purpose of distinguishing one component from another. For example, a first element may be termed a second element, and similarly, a second element may be termed a first element.

It should be understood that when an element is referred to as being “connected” to another element, it may be directly connected or connected to the other element, but other elements may exist in the middle.

Terms used in the examples are used only for descriptive purposes and should not be construed as limiting. Singular expressions include plural expressions unless the context clearly dictates otherwise. In this specification, terms such as "include" or "have" are intended to designate that there is a feature, number, step, operation, component, part, or combination thereof described in the specification, but one or more other features It should be understood that the presence or addition of numbers, steps, operations, components, parts, or combinations thereof is not precluded.

Unless defined otherwise, all terms used herein, including technical or scientific terms, have the same meaning as commonly understood by a person of ordinary skill in the art to which the embodiment belongs. Terms such as those defined in commonly used dictionaries should be interpreted as having a meaning consistent with the meaning in the context of the related art, and unless explicitly defined in the present application, they should not be interpreted in an ideal or excessively formal meaning. don't

Among the accompanying drawings, FIG. 1 is a perspective view showing a diagnostic strip manufacturing apparatus according to the present invention, FIG. 2 is a perspective view showing a state in which a control unit is removed from the diagnostic strip manufacturing apparatus according to the present invention, and FIG. 3 is a diagnostic strip manufacturing apparatus according to the present invention. A partially enlarged front view of the 'pad compartment' in the strip manufacturing apparatus, Figure 4 is an enlarged view of the pad compartment in FIG. 3, Figure 5a is a front view showing the operation of the pad compartment in FIG. 5B is an enlarged view of the main part of FIG. 5A, FIG. 6 is an enlarged perspective view of the 'reagent injection unit' in the apparatus for manufacturing a diagnostic strip according to the present invention, and FIG. 7 is an enlarged perspective view of the main part of FIG.

1 to 7, the apparatus for manufacturing a diagnostic strip according to the present invention,

A flat part 120 is formed on the upper part, both side walls 140 formed symmetrically on both sides of the flat part 120 and long holes 142 are formed in the longitudinal direction, and the upper part of the flat part 120 in the longitudinal direction A body 100 in which a plurality of rail grooves 122 are formed;

A rod 210 coupled to both sides of the long hole 142 of both side walls 140, a plurality of fixtures 220 formed on the rod 210 and inserted into the rail groove 122, and the rod 210 A pad holder 200 composed of a driving unit (not shown) for moving the ) to move it forward and backward along the long hole 142, so that the fabric S is adhered to the plurality of fixtures 220;

A rotating rod 320 connecting both side walls 140 of the main body 100, a lower portion connected to the rotating rod 320, and a pad attachment surface 340 formed on the upper portion to rotate the pad P to the fabric ( S) attached to one side of the pad storage unit 300;

The cutting part 400 is mounted on the end of the flat part 120 of the main body 100 and has a cutter blade 420 that is mounted on the pad holding part 200 and cuts the conveyed fabric S to a certain width. It is composed of;

The main body 100 is seated on the ground and has a box shape, a flat flat portion 120 is formed on the top, and side walls 140 are formed on both sides of the flat portion 120, respectively.

A plurality of rail grooves 122 are formed in parallel to the side wall 140 on the plane portion 120 . The fixtures 220 of the pad holder 200 may be coupled to the plurality of rail grooves 122 and moved forward and backward.

The pad holder 200 has both ends of a bar-shaped rod 210 coupled to both side walls 140 of the main body 100, respectively. Long holes 142 are formed in both side walls 140 in the longitudinal direction.

Therefore, the rod 210 is coupled to the long hole 142 of both side walls 140, and the rod 210 can be moved in the forward and backward directions by the driving unit.

The drive unit is attached to the motor 280, the LM guide 282 formed in the longitudinal direction so that the roller (not shown) connected to the motor 280 travels, and the motor 280, and the rod of the pad holder 200 ( 210) is composed of a connecting plate 281 to which it is connected.

Therefore, when the motor 280 is turned on and the roller is rotated forward or backward, it moves forward and backward along the LLM guide 282, and the connecting plate 281 and the rod 210 connected thereto can move forward and backward.

A plurality of fixtures 220 are coupled to the rod 210, and each fixture 220 has a lower portion fitted into the rail groove 122 so that it can move linearly along the rail groove 122.

The plurality of fixtures 220 are arranged in parallel so that the plurality of fixtures 220 move forward or backward along with the movement of the rod 210 at the same time, and the fabric fabric S is placed at the tip of the plurality of fixtures 220. Since it is a state, it is possible to move the fabric (S).

The fabric (S) is a special textile material of approximately rectangular shape, and pads (P) are attached to both sides of the upper surface. A plurality of fixtures 220 are mounted on the long side of the fabric (S).

The pad (P) is mounted in the pad storage unit 300 and then attached to a specific location of the fabric (S).

The pad receiving unit 300 includes a flat panel 330, a plurality of mounting protrusions 350 formed on one end of the panel 330 in the width and length direction, and a plurality of formed on one side of each holding protrusion 350. An air intake hole 360, a vacuum passage 370 formed inside the panel 330 and communicating with the air intake hole 360, and a vacuum pump connected to the vacuum passage 370 to generate a vacuum suction force (not shown). City) is composed of.

Since vacuum pressure is formed by the on operation of the vacuum pump and continuous suction can be performed through the intake hole 360, the pad P is in close contact with the intake hole 360 on the front of the panel 330. It can be in a fixed state.

In addition, since the lower part of the pad P is supported by the protrusion 350, even when the panel 330 is erected, it can be maintained in a fixed state since it is supported by the protrusion 350 together with vacuum pressure.

Rotate the pad storage unit 300 downward so that the pad (P) is attached to one side of the upper surface of the fabric (S).

Since an adhesive is applied to the upper surface of the fabric (S), the pad (P) can be attached thereto.

Two pads (P) are attached to both sides of the fabric (S) at a predetermined distance apart. A reagent is applied between the two pads P.

The reagent is sprayed and applied by the reagent injection unit 500 .

A reagent injection unit 500 mounted on one side wall 140 of the main body 100 and formed on one side of the rail groove 122; is configured to include.

The reagent injection unit 500 includes a mounting table 510 mounted on one side wall 140 of the main body 100, a mounting bar 520 coupled to the mounting table 510, and the mounting bar ( 520), a bracket 530 that can be moved along the mounting bar 520, a connecting rod 540 vertically coupled to the bottom of the bracket 530, and mounted on the lower end of the connecting rod 540 A nozzle 550, a hose 560 connected to the nozzle 550, a reagent bottle 570 connected to the hose 560 and mounted on one side wall 140, and the reagent bottle 570 It is configured to include a piston 580 coupled to the inside of and a pressure unit 590 for inhaling or discharging a drug through a nozzle 550 by raising or lowering the piston 580.

The pressing unit 590 may be a motor or a pneumatic cylinder.

Accordingly, when the pressure unit 590 is turned on and the piston 580 is raised, the reagent may be sucked through the nozzle 550 and filled in the reagent bottle 570 .

That is, when the pressure unit 590 is turned on after the nozzle 550 is inserted into the reagent bottle, the reagent is sucked and filled into the reagent bottle. The nozzle 550 is composed of two. Of course, the number of nozzles 550 may be freely increased or decreased.

Thereafter, the reagent bottle is removed, and when the nozzle 550 is driven forward by the forward movement of the pad holder 200 while the nozzle 550 is in close proximity to the upper surface of the fabric paper S, the piston 580 descends at the same time. A reagent is discharged through the nozzle 550 .

Therefore, the reagent may be continuously discharged to the fabric paper S and applied in the form of two lines.

Preferably, the bracket 530 has a screw shaft 532 screwed to the connector 540, and a handle gauge 533 is formed on the screw shaft 532 to adjust the height of the bracket 530. So that the height of the nozzle 550 is adjusted.

A stopper 515 composed of a screw shaft and a screw head that is screwed to the mount 510 and is fixed or spaced apart from the mount 520 to exert a fixing force.

A roller 542 is formed at the bottom of the connecting rod 540 and can be rotationally driven in a supported state on the upper surface of the fabric (S).

Therefore, in a state in which the nozzle 550 is supported on the top of the fabric fabric S, the roller 542 is rotationally driven by the movement of the fabric fabric S to assist in more stable movement of the fabric fabric S. A distance between the nozzle 550 and the fabric fabric S may be maintained constant.

The operation of the present invention configured as described above is described as follows.

After the fabric (S) is mounted so that the plurality of fixtures 220 of the pad holder 200 support the long side, the controller (R) commands the movement distance to the pad holder by the specified distance.

200 is moved so that the original paper arrives at a predetermined position.

Thereafter, the pad (P) is placed in close contact with the pad storage unit (300), and then the panel (330) is rotated downward in a state where vacuum pressure is applied so that the pad (P) adheres to the fabric (S) and vacuum pressure is applied. The pad (P) is attached to the fabric (S) by blocking it.

Thereafter, the panel 330 is rotated in the opposite direction so that it is erected vertically to return to its original state.

The fabric S to which the pad P is attached is rotated so that one short side faces the forward direction, and the other short side is placed on the fixture 220.

After that, the pad holding part 200 moves forward and approaches the cutting part 400 .

The cutting unit 400 can manufacture diagnostic strips by sequentially cutting from the end of the fabric S while the cutter blade 420 moves up and down according to the cutting interval value previously input to the control unit.

The present invention is not limited by the above-described embodiments and the accompanying drawings, and various modifications and applications not exemplified within the scope of the technical idea of the present invention are possible, as well as substitution of components and equivalent other embodiments. Since it can be changed, the content related to the modification and application of the features of the present invention should be construed as being included within the scope of the present invention.

100: main body 120: flat part
140: side wall 122: rail groove
142: long hole
200: pad holder 210: rod
220: fixture S: fabric
P: pad
300: pad storage unit 320: rotating bar
330: panel 340: pad attachment surface
350: protrusion 360: intake hole
370: vacuum passage
400: cutting part 420: cutter blade
500: reagent injection unit 510: mounting table
520: mounting bar 530: bracket
540: connecting rod 550: nozzle
560: hose 570: reagent bottle
580: Piston 590: Pressing part

Claims (5)

a main body having a plane portion formed on an upper portion, both side walls symmetrically formed on both sides of the plane portion and elongated holes formed in the longitudinal direction, and a plurality of rail grooves formed on the upper portion of the plane portion in the longitudinal direction;
It consists of a rod coupled to both sides of the long hole of the both side walls, a plurality of fixtures formed on the rod and inserted into the rail groove, and a drive unit that moves the rod to move forward and backward along the long hole, and the plurality of fixtures A pad holding portion so that the fabric is in close contact with the;
a rotating rod connecting both side walls of the main body, and a pad storage unit having a lower portion connected to the rotating rod and having a pad attachment surface formed on the upper portion to attach the pad to one side of the fabric while being rotated;
A cutting unit mounted on the end of the flat surface of the main body and having a cutter blade mounted on the pad holding unit to cut the conveyed fabric into a predetermined width;
A diagnostic strip manufacturing apparatus comprising a. According to claim 1,
The pad storage part
A flat panel, a plurality of protrusions formed on one end of the panel in the width and length direction, a plurality of intake holes formed on one side of each protrusion, a vacuum passage formed inside the panel and communicating with the intake holes, and the vacuum An apparatus for manufacturing a diagnostic strip comprising a vacuum pump connected to the passage to generate a vacuum suction force. According to claim 1,
A reagent injection unit mounted on one side wall of the main body and formed on one side of the rail groove;
The reagent injection part
A mounting table mounted on one side wall of the main body, a mounting rod coupled to the mounting table, a bracket connected to the mounting rod and movable along the mounting rod, and a connecting rod vertically coupled to the lower portion of the bracket , a nozzle mounted on the lower end of the connecting table, a hose connected to the nozzle, a reagent container connected to the hose and mounted on one side wall, a piston coupled to the inside of the reagent container, and a nozzle by raising or lowering the piston An apparatus for manufacturing a diagnostic strip, characterized in that it comprises a pressurizing unit for inhaling or discharging a drug through the. According to claim 3,
The pressing part is a motor or a pneumatic cylinder,
The apparatus for manufacturing a diagnostic strip according to claim 1 , wherein a screw shaft screwed to the connecting rod is formed on the bracket, and a handle gauge is formed on the screw shaft to adjust the lift height of the bracket so that the height of the nozzle is adjusted. According to claim 3,
and a stopper screwed to the mount and composed of a screw shaft and a screw head that are fixed or spaced apart from the mounting bar to exert a fixing force.

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