KR102518146B1 - 향상된 인터페론 치료 - Google Patents

향상된 인터페론 치료 Download PDF

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KR102518146B1
KR102518146B1 KR1020207018114A KR20207018114A KR102518146B1 KR 102518146 B1 KR102518146 B1 KR 102518146B1 KR 1020207018114 A KR1020207018114 A KR 1020207018114A KR 20207018114 A KR20207018114 A KR 20207018114A KR 102518146 B1 KR102518146 B1 KR 102518146B1
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KR20200078693A (ko
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나이젤 파커
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에프케이디 테라피즈 리미티드,
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/212—IFN-alpha
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K16/3023—Lung
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3061—Blood cells
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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  • Immunology (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
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  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Hematology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1020207018114A 2016-02-15 2017-02-11 향상된 인터페론 치료 Active KR102518146B1 (ko)

Priority Applications (1)

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KR1020227035962A KR20220147693A (ko) 2016-02-15 2017-02-11 향상된 인터페론 치료

Applications Claiming Priority (4)

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US201662295268P 2016-02-15 2016-02-15
US62/295,268 2016-02-15
PCT/US2017/017568 WO2017142818A1 (en) 2016-02-15 2017-02-11 Improved interferon therapy
KR1020187026724A KR102129195B1 (ko) 2016-02-15 2017-02-11 향상된 인터페론 치료

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US (2) US10335461B2 (enExample)
EP (1) EP3416727A4 (enExample)
JP (5) JP6995061B2 (enExample)
KR (3) KR102518146B1 (enExample)
CN (2) CN113925964A (enExample)
CA (2) CA3014759C (enExample)
WO (1) WO2017142818A1 (enExample)

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EP3810151B1 (en) * 2018-06-20 2025-08-06 Yale University Rig-i agonists and treatments using same
KR20210106531A (ko) * 2018-12-21 2021-08-30 에임 이뮤노테크 인코포레이티드 암 치료를 위한 조성물 및 방법
MX2021011654A (es) * 2019-04-03 2022-02-21 Targimmune Therapeutics Ag Inmunoterapia para el tratamiento del cancer.
AU2021250709A1 (en) * 2020-03-30 2022-10-13 Trizell Ltd. Compositions and methods for treating cancer

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WO2015095811A2 (en) * 2013-12-20 2015-06-25 The Board Institute Inc. Combination therapy with neoantigen vaccine

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US20090028857A1 (en) * 2007-07-23 2009-01-29 Cell Genesys, Inc. Pd-1 antibodies in combination with a cytokine-secreting cell and methods of use thereof
EP2262837A4 (en) * 2008-03-12 2011-04-06 Merck Sharp & Dohme PD-1 BINDING PROTEINS
US20130017199A1 (en) * 2009-11-24 2013-01-17 AMPLIMMUNE ,Inc. a corporation Simultaneous inhibition of pd-l1/pd-l2
CN103536917B (zh) * 2013-10-30 2015-03-11 苏州丁孚靶点生物技术有限公司 干扰素在治疗肿瘤中的用途及相关的产品和方法
KR20160093012A (ko) * 2013-11-05 2016-08-05 코그네이트 바이오서비시즈, 인코포레이티드 암 치료를 위한 체크포인트 억제제 및 치료제의 배합물
MX389663B (es) * 2014-10-14 2025-03-20 Novartis Ag Moleculas de anticuerpo que se unen a pd-l1 y usos de las mismas.

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WO2015095811A2 (en) * 2013-12-20 2015-06-25 The Board Institute Inc. Combination therapy with neoantigen vaccine

Non-Patent Citations (1)

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Tobias Bald 등. Cancer Discov. 4(6) 674-87. 2014.*

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KR102129195B1 (ko) 2020-07-01
KR20220147693A (ko) 2022-11-03
JP7030156B2 (ja) 2022-03-04
CN108697781A (zh) 2018-10-23
CN113925964A (zh) 2022-01-14
CA3014759C (en) 2020-09-22
CA3089875A1 (en) 2017-08-24
JP2020122017A (ja) 2020-08-13
EP3416727A1 (en) 2018-12-26
US20190255153A1 (en) 2019-08-22
JP2019508497A (ja) 2019-03-28
CA3014759A1 (en) 2017-08-24
KR20200078693A (ko) 2020-07-01
JP2020122018A (ja) 2020-08-13
EP3416727A4 (en) 2019-10-09
JP6995061B2 (ja) 2022-02-04
JP2020122019A (ja) 2020-08-13
KR20180123676A (ko) 2018-11-19
JP2022113832A (ja) 2022-08-04
US20170232071A1 (en) 2017-08-17
WO2017142818A1 (en) 2017-08-24
US10335461B2 (en) 2019-07-02
JP7113864B2 (ja) 2022-08-05

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