KR102505995B1 - FcRn 항체 및 이의 사용 방법 - Google Patents

FcRn 항체 및 이의 사용 방법 Download PDF

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KR102505995B1
KR102505995B1 KR1020197006049A KR20197006049A KR102505995B1 KR 102505995 B1 KR102505995 B1 KR 102505995B1 KR 1020197006049 A KR1020197006049 A KR 1020197006049A KR 20197006049 A KR20197006049 A KR 20197006049A KR 102505995 B1 KR102505995 B1 KR 102505995B1
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cdr
seq
sequence
antibody
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KR20190037285A (ko
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레오나 이. 링
수카리타 로이
나타니엘 워쉬번
마릴린 케리
데이비드 제이. 킹
제임스 삼세 미도르
안토니 매닝
잔 힐슨
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모멘타 파머슈티컬스 인코포레이티드
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/283—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against Fc-receptors, e.g. CD16, CD32, CD64
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
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    • C07—ORGANIC CHEMISTRY
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    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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    • C07K2317/565—Complementarity determining region [CDR]
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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KR1020197006049A 2016-07-29 2017-07-31 FcRn 항체 및 이의 사용 방법 Active KR102505995B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020237006882A KR102717601B1 (ko) 2016-07-29 2017-07-31 FcRn 항체 및 이의 사용 방법

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662368803P 2016-07-29 2016-07-29
US201662368770P 2016-07-29 2016-07-29
US62/368,770 2016-07-29
US62/368,803 2016-07-29
PCT/US2017/044765 WO2018023136A1 (en) 2016-07-29 2017-07-31 Fcrn antibodies and methods of use thereof

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KR1020237006882A Division KR102717601B1 (ko) 2016-07-29 2017-07-31 FcRn 항체 및 이의 사용 방법

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KR20190037285A KR20190037285A (ko) 2019-04-05
KR102505995B1 true KR102505995B1 (ko) 2023-03-08

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KR1020197006049A Active KR102505995B1 (ko) 2016-07-29 2017-07-31 FcRn 항체 및 이의 사용 방법
KR1020247033727A Pending KR20240151878A (ko) 2016-07-29 2017-07-31 FcRn 항체 및 이의 사용 방법
KR1020237006882A Active KR102717601B1 (ko) 2016-07-29 2017-07-31 FcRn 항체 및 이의 사용 방법

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KR1020237006882A Active KR102717601B1 (ko) 2016-07-29 2017-07-31 FcRn 항체 및 이의 사용 방법

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US (2) US11345751B2 (https=)
EP (2) EP3491025B1 (https=)
JP (3) JP7094941B2 (https=)
KR (3) KR102505995B1 (https=)
CN (2) CN109790221B (https=)
AU (1) AU2017301915B2 (https=)
BR (1) BR112019001806A2 (https=)
CA (1) CA3032415A1 (https=)
DK (1) DK3491025T3 (https=)
ES (1) ES2968439T3 (https=)
FI (1) FI3491025T3 (https=)
HR (1) HRP20240048T1 (https=)
HU (1) HUE065780T2 (https=)
IL (3) IL320058A (https=)
LT (1) LT3491025T (https=)
NZ (1) NZ789871A (https=)
PL (1) PL3491025T3 (https=)
PT (1) PT3491025T (https=)
RS (1) RS65070B1 (https=)
SG (1) SG11201900813RA (https=)
SI (1) SI3491025T1 (https=)
SM (1) SMT202400004T1 (https=)
WO (1) WO2018023136A1 (https=)

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SMT202400004T1 (it) * 2016-07-29 2024-03-13 Momenta Pharmaceuticals Inc Anticorpi fcrn e loro metodi di utilizzo
SG10202112298TA (en) * 2017-05-11 2021-12-30 Nat Univ Singapore Targeted prevention of maternal to foetal vertical transmission of infection
CA3081144A1 (en) 2017-12-08 2019-06-13 Argenx Bvba Use of fcrn antagonists for treatment of generalized myasthenia gravis
KR102904658B1 (ko) * 2017-12-13 2025-12-29 모멘타 파머슈티컬스 인코포레이티드 FcRn 항체 및 이의 사용 방법
US12054558B2 (en) 2018-05-23 2024-08-06 The Jackson Laboratory Anti-NGly-1 antibodies and methods of use
US12202900B2 (en) 2018-06-08 2025-01-21 argenx BV Compositions and methods for treating immune thrombocytopenia
WO2020023310A1 (en) * 2018-07-20 2020-01-30 Williams Eva Compositions of fcrn antibodies and methods of use thereof
CN113518783A (zh) * 2018-07-20 2021-10-19 动量制药公司 FcRn抗体组合物
EP3969125A4 (en) * 2019-05-17 2023-01-11 Alexion Pharmaceuticals, Inc. USE OF ANTI-FCRN ANTIBODIES IN THE TREATMENT OF PEMPHIGHUS AND PEMPHIGOID DISEASES
EP4007605A4 (en) * 2019-08-01 2023-08-16 Momenta Pharmaceuticals, Inc. ANTI-FCRN ANTIBODIES AND METHODS OF USE THEREOF
AU2020387399A1 (en) * 2019-11-19 2022-05-19 Immunovant Sciences Gmbh Methods of treating warm autoimmune hemolytic anemia using anti-FcRn antibodies
JP2023509195A (ja) 2020-01-08 2023-03-07 アルジェニクス ビーブイ 天疱瘡症を治療する方法
CN116234827A (zh) * 2021-09-03 2023-06-06 舒泰神（北京）生物制药股份有限公司 特异性识别FcRn的抗体及其应用
CN113912730B (zh) * 2021-12-14 2022-03-04 北京科诺信诚科技有限公司 缓释的抗FcRn抗体或抗原结合片段及其应用
CN119698429A (zh) 2022-06-15 2025-03-25 阿根思有限公司 Fcrn结合分子及使用方法
AR131560A1 (es) * 2023-01-06 2025-04-09 argenx BV Métodos para tratar pots mediante el uso de antagonistas de fcrn
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