KR102499918B1 - 근위축성 측삭 경화증 치료제 - Google Patents
근위축성 측삭 경화증 치료제 Download PDFInfo
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- KR102499918B1 KR102499918B1 KR1020227012378A KR20227012378A KR102499918B1 KR 102499918 B1 KR102499918 B1 KR 102499918B1 KR 1020227012378 A KR1020227012378 A KR 1020227012378A KR 20227012378 A KR20227012378 A KR 20227012378A KR 102499918 B1 KR102499918 B1 KR 102499918B1
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- ghrelin
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Classifications
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
- C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Immunology (AREA)
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- Pain & Pain Management (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Marine Sciences & Fisheries (AREA)
- Cell Biology (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012234300 | 2012-10-24 | ||
| JPJP-P-2012-234300 | 2012-10-24 | ||
| PCT/JP2013/078743 WO2014065341A1 (ja) | 2012-10-24 | 2013-10-23 | 筋萎縮性側索硬化症治療剤 |
| KR1020207026038A KR20200108494A (ko) | 2012-10-24 | 2013-10-23 | 근위축성 측삭 경화증 치료제 |
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| Application Number | Title | Priority Date | Filing Date |
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| KR1020207026038A Division KR20200108494A (ko) | 2012-10-24 | 2013-10-23 | 근위축성 측삭 경화증 치료제 |
Publications (2)
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| KR20220051418A KR20220051418A (ko) | 2022-04-26 |
| KR102499918B1 true KR102499918B1 (ko) | 2023-02-14 |
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| EA201791038A1 (ru) | 2014-11-12 | 2017-11-30 | Лирик Фармасьютикалз Инк. | Лечение непереносимости энтерального питания |
| WO2017083882A1 (en) * | 2015-11-11 | 2017-05-18 | Lyric Pharmaceuticals Inc. | Treatment of enteral feeding intolerance and other conditions using ulimorelin analogs |
| MA54383A (fr) * | 2018-12-06 | 2021-10-13 | Biogen Ma Inc | Protéine neurofilamenteuse pour guider une intervention thérapeutique dans la sclérose laterale amyotrophique |
| EP3924739A1 (en) | 2019-02-12 | 2021-12-22 | Biogen MA Inc. | Biomarkers of progressive multifocal leukoencephalopathy |
| GEAP202516774A (en) | 2022-11-03 | 2025-06-25 | Lumos Pharma Inc | Compactable oral formulations of ibutamoren |
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| US5668254A (en) | 1990-05-11 | 1997-09-16 | Romano Deghenghi | D-2-alkyl-tryptophan and peptides containing same |
| US5663146A (en) | 1991-08-22 | 1997-09-02 | Administrators Of The Tulane Educational Fund | Polypeptide analogues having growth hormone releasing activity |
| US5578593A (en) | 1992-12-11 | 1996-11-26 | Merck & Co., Inc. | Spiro piperidines and homologs promote release of growth hormone |
| TW432073B (en) | 1995-12-28 | 2001-05-01 | Pfizer | Pyrazolopyridine compounds |
| CN1161333C (zh) | 1998-08-20 | 2004-08-11 | 住友制药株式会社 | 作为生长激素释放剂的2-羟基吲哚衍生物 |
| CA2380058C (en) * | 1999-07-23 | 2011-08-09 | Kenji Kangawa | Novel peptides |
| UA73530C2 (uk) | 1999-11-10 | 2005-08-15 | Ново Нордіск А/С | Сполука з властивостями вивільнювати гормон росту |
| ATE304373T1 (de) * | 1999-12-28 | 2005-09-15 | Kaken Pharma Co Ltd | Nervenschutzmittel |
| ATE302181T1 (de) | 2000-06-13 | 2005-09-15 | Zentaris Gmbh | Verbindungen zur stimulation der sekretion von wachstumshormonen |
| EP1493747B1 (en) | 2002-04-11 | 2012-12-19 | Daiichi Sankyo Company, Limited | Process for producing modified peptide |
| US7476653B2 (en) | 2003-06-18 | 2009-01-13 | Tranzyme Pharma, Inc. | Macrocyclic modulators of the ghrelin receptor |
| JP2005239712A (ja) | 2004-01-30 | 2005-09-08 | Kaken Pharmaceut Co Ltd | 神経突起伸展剤 |
| WO2006079077A2 (en) * | 2005-01-20 | 2006-07-27 | Acadia Pharmaceuticals Inc. | Use of diltiazem or analogs thereof as modulators of ghrelin receptor |
| US7829589B2 (en) | 2005-06-10 | 2010-11-09 | Elixir Pharmaceuticals, Inc. | Sulfonamide compounds and uses thereof |
| EP1938814A4 (en) * | 2005-10-18 | 2009-06-03 | Ono Pharmaceutical Co | PHARMACEUTICAL PRODUCT FOR PROTECTING MOTOR NERVE IN PATIENTS WITH AMYOTROPHIC LATERAL SCLEROSIS |
| HUE044182T2 (hu) | 2006-06-07 | 2019-10-28 | Genzyme Corp | Génterápia amiotrófiás laterális szklerózis és más gerincvelõ-rendellenességek kezelésére |
| JP2008127377A (ja) | 2006-11-24 | 2008-06-05 | Jichi Medical Univ | Ｇｈｓ−ｒ作動薬を含有してなるメタボリックシンドローム又は高血圧症の予防・治療剤。 |
| KR100946084B1 (ko) | 2008-03-27 | 2010-03-10 | 주식회사 하이닉스반도체 | 반도체 소자의 수직형 트랜지스터 및 그 형성방법 |
| WO2009121759A2 (en) * | 2008-04-03 | 2009-10-08 | F. Hoffmann-La Roche Ag | Use of pegylated igf-i variants for the treatment of neuromuscular disorders |
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2013
- 2013-10-23 CA CA2889499A patent/CA2889499C/en active Active
- 2013-10-23 WO PCT/JP2013/078743 patent/WO2014065341A1/ja not_active Ceased
- 2013-10-23 AU AU2013335678A patent/AU2013335678B9/en active Active
- 2013-10-23 CN CN201380066625.1A patent/CN104853778A/zh active Pending
- 2013-10-23 RU RU2015119472A patent/RU2655811C2/ru active
- 2013-10-23 EP EP13848825.9A patent/EP2913063B1/en not_active Not-in-force
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- 2013-10-23 CN CN201910808882.7A patent/CN110354265A/zh active Pending
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- 2013-10-23 IN IN4172DEN2015 patent/IN2015DN04172A/en unknown
- 2013-10-23 KR KR1020157010085A patent/KR20150070180A/ko not_active Ceased
- 2013-10-23 US US14/437,459 patent/US20150265680A1/en not_active Abandoned
- 2013-10-23 KR KR1020207026038A patent/KR20200108494A/ko not_active Withdrawn
- 2013-10-23 BR BR112015009107A patent/BR112015009107A2/pt not_active Application Discontinuation
Non-Patent Citations (1)
| Title |
|---|
| Lee et al., Korean J Physiol Pharmacol., 16, pp.43-48 (2012.02.)* |
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| EP2913063A4 (en) | 2016-07-20 |
| RU2015119472A (ru) | 2016-12-20 |
| US20150265680A1 (en) | 2015-09-24 |
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| KR20200108494A (ko) | 2020-09-18 |
| BR112015009107A2 (pt) | 2017-11-14 |
| KR20150070180A (ko) | 2015-06-24 |
| CA2889499A1 (en) | 2014-05-01 |
| JP6262661B2 (ja) | 2018-01-17 |
| RU2655811C2 (ru) | 2018-05-29 |
| AU2013335678B2 (en) | 2017-10-26 |
| CN110354265A (zh) | 2019-10-22 |
| AU2013335678B9 (en) | 2024-12-12 |
| KR20220051418A (ko) | 2022-04-26 |
| HK1214152A1 (en) | 2016-07-22 |
| EP2913063B1 (en) | 2019-09-11 |
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