KR102499746B1 - 세포 분비 분석을 위한 장치 및 방법 - Google Patents

세포 분비 분석을 위한 장치 및 방법 Download PDF

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KR102499746B1
KR102499746B1 KR1020227004273A KR20227004273A KR102499746B1 KR 102499746 B1 KR102499746 B1 KR 102499746B1 KR 1020227004273 A KR1020227004273 A KR 1020227004273A KR 20227004273 A KR20227004273 A KR 20227004273A KR 102499746 B1 KR102499746 B1 KR 102499746B1
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칼 라스 젱히스 한센
캐슬린 리사인고
베로니크 레카울트
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더 유니버시티 오브 브리티쉬 콜롬비아
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    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads or physically stretching molecules
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
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    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
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    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
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    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
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    • C—CHEMISTRY; METALLURGY
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    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/46—Means for regulation, monitoring, measurement or control, e.g. flow regulation of cellular or enzymatic activity or functionality, e.g. cell viability
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
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    • G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
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  • Dispersion Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
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  • Fluid Mechanics (AREA)
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  • Signal Processing (AREA)
  • Virology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
KR1020227004273A 2016-03-17 2017-03-17 세포 분비 분석을 위한 장치 및 방법 Active KR102499746B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201662309663P 2016-03-17 2016-03-17
US62/309,663 2016-03-17
PCT/CA2017/050341 WO2017156634A1 (en) 2016-03-17 2017-03-17 Devices and methods for cellular secretion analysis
KR1020187029795A KR102362176B1 (ko) 2016-03-17 2017-03-17 세포 분비 분석을 위한 장치 및 방법

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KR102499746B1 true KR102499746B1 (ko) 2023-02-16

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KR1020187029795A Active KR102362176B1 (ko) 2016-03-17 2017-03-17 세포 분비 분석을 위한 장치 및 방법

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US (1) US20200156071A1 (https=)
EP (1) EP3430158A4 (https=)
JP (2) JP6980683B2 (https=)
KR (2) KR102499746B1 (https=)
CN (2) CN109154017B (https=)
AU (2) AU2017233729A1 (https=)
CA (1) CA3015237A1 (https=)
WO (1) WO2017156634A1 (https=)

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CN112210487A (zh) * 2020-09-30 2021-01-12 英卓数科(北京)科技有限公司 高通量筛选分泌抗原特异性抗体浆细胞的装置及方法
CN114441752B (zh) * 2020-11-03 2024-11-26 中国科学院苏州纳米技术与纳米仿生研究所 一种筛选方法
CN112785206B (zh) * 2021-03-03 2023-06-30 中国科学院地理科学与资源研究所 一种金属行业涉污企业影响范围模拟与风险评估方法
DE102021204675B4 (de) * 2021-05-07 2023-05-17 Lpkf Laser & Electronics Se Vorrichtung und Verfahren zur Zellkultivierung
US12091715B2 (en) 2022-04-21 2024-09-17 Paragon Genomics, Inc. Methods and compositions for reducing base errors of massive parallel sequencing using triseq sequencing
US11680293B1 (en) 2022-04-21 2023-06-20 Paragon Genomics, Inc. Methods and compositions for amplifying DNA and generating DNA sequencing results from target-enriched DNA molecules
CN115739040B (zh) * 2022-11-01 2023-06-23 南京鼓楼医院 一种仿生水母颗粒吸附剂、制备方法及应用
WO2024155998A1 (en) * 2023-01-20 2024-07-25 Massachusetts Institute Of Technology Hanging drop-based microfluidic system, device, and method for liquid exchange for vitrification of a specimen
CN119881285B (zh) * 2025-03-25 2025-07-11 吉林大学 用于内分泌异常检测的智能分析系统及方法

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US20200156071A1 (en) 2020-05-21
CN109154017A (zh) 2019-01-04
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