KR102473971B1 - 항종양 활성을 갖는 아릴 아마이드 유도체 - Google Patents
항종양 활성을 갖는 아릴 아마이드 유도체 Download PDFInfo
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- KR102473971B1 KR102473971B1 KR1020227002880A KR20227002880A KR102473971B1 KR 102473971 B1 KR102473971 B1 KR 102473971B1 KR 1020227002880 A KR1020227002880 A KR 1020227002880A KR 20227002880 A KR20227002880 A KR 20227002880A KR 102473971 B1 KR102473971 B1 KR 102473971B1
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- fluoro
- methyl
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- difluoro
- iodoanilino
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- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
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- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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| US20160222014A1 (en) | 2013-09-10 | 2016-08-04 | Asana Biosciences, Llc | Compounds for regulating fak and/or src pathways |
| JP2016534027A (ja) | 2013-10-25 | 2016-11-04 | シャンハイ ヘンルイ ファーマスーティカル カンパニー リミテッドShanghai Hengrui Pharmaceutical Co., Ltd. | ピリジンのケトン誘導体、それらの製造方法、およびそれらの医薬適用 |
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